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https://www.readbyqxmd.com/read/29036292/association-between-implantable-cardioverter-defibrillator-therapy-and-different-lead-positions-in-patients-with-cardiac-resynchronization-therapy
#1
Mads Brix Kronborg, Jens Brock Johansen, Jens Haarbo, Sam Riahi, Berit Thornvig Philbert, Ole Dan Jørgensen, Jens Cosedis Nielsen
Aims: To evaluate the impact of different right and left ventricular lead positions (RV-LP and LV-LP) on the risk of therapy for ventricular tachycardia/ventricular fibrillation in patients with a cardiac resynchronization therapy device (CRT-D). Methods and results: We performed a large nationwide cohort study on patients in Denmark receiving a CRT-D device from 2008 to 2012 from the Danish Pacemaker and implantable cardioverter defibrillator (ICD) registry. Lead positions were registered during the implantation and categorized as anterior/lateral/posterior and basal/mid-ventricular/apical for the LV-LP, and as apical/non-apical for the RV-LP...
September 27, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29030709/bleeding-risk-of-submuscular-icd-implantation-with-continued-oral-anticoagulation-versus-heparin-bridging-therapy
#2
Simon Pecha, Ayhan Ayikli, Iris Wilke, Samer Hakmi, Yalin Yildirim, Nils Gosau, Hermann Reichenspurner, Stephan Willems, Muhammet Ali Aydin
Recent studies have shown that subcutaneous or subfascial pacemaker- and ICD implantation with continued oral anticoagulation therapy is associated with lower risk for bleeding complications, when compared to heparin bridging strategies. However, ICD generators are often implanted submuscularly. We therefore compared the bleeding risk with continued phenprocoumon therapy vs. heparin bridging in patients receiving submuscular ICD implantation. Between 01/2013 and 12/2013, 104 patients with need for oral anticoagulation received submuscular ICD or CRT-D implantation in our institution...
October 13, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29030235/impact-of-ventricular-tachycardia-ablation-on-healthcare-utilization
#3
Jeffrey R Winterfield, Alexander R Kent, Edward Karst, Nirav Dalal, Srijoy Mahapatra, T Jared Bunch, Matthew R Reynolds, David J Wilber
BACKGROUND: Catheter ablation of ventricular tachycardia (VT) has been shown to reduce the number of recurrent shocks in patients with implantable cardioverter defibrillators (ICDs). However, it remains unclear how VT ablation affects post-procedural medical and pharmaceutical usage. OBJECTIVES: The objective of this study was to investigate changes in healthcare resource utilization (HCRU) following VT ablation. METHODS: This large-scale, real-world, retrospective study used the MarketScan databases to identify patients in the U...
October 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29028784/manufacturer-change-and-risk-of-system-related-complications-after-implantable-cardioverter-defibrillator-replacement-physicians-survey-and-data-from-the-detect-long-term-complications-after-implantable-cardioverter-defibrillator-replacement-registry
#4
Mauro Biffi, Endrj Menardi, Maria L Narducci, Ernesto Ammendola, Loredana Messano, Fabrizio Giofrè, Claudia Baiocchi, Davide Saporito, Fabio Lissoni, Matteo Bertini, Attilio Pierantozzi, Gianluca Zingarini, Maurizio Malacrida, Matteo Ziacchi
AIMS: Some barriers seem to exist in changing implantable cardioverter defibrillator (ICD) manufacturer at the time of device replacement. We sought to understand the obstacles to changing ICD manufacturer within the cohort of patients enrolled in the Detect Long-term Complications After ICD Replacement Registry. METHODS: We analyzed 784 consecutive ICD/cardiac resynchronization therapy defibrillator (CRT-D) device replacements within a 1.5-year time-frame in 36 Italian centers to evaluate potential factors associated with changing manufacturers and system-related complications...
October 11, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29021862/adaptive-cardiac-resynchronization-therapy-for-dilated-cardiomyopathy-with-functional-mitral-regurgitation
#5
Yoshiki Nagata, Yoichiro Nakagawa, Yusuke Takeda, Kenji Emoto, Masaki Kinoshita, Akio Chikata, Michiro Maruyama, Kazuo Usuda
We report the case of a man in his 60s who had dilated cardiomyopathy with severe functional mitral regurgitation. Four years after a cardiac resynchronization therapy (CRT) device with an implantable cardioverter defibrillator was implanted, this device was replaced with an adaptive CRT device because of battery consumption. Seven months after replacement of this device, the left ventricular pacing to right ventricular activation and the atrioventricular delay from automatic adjustments contributed to less functional mitral regurgitation...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29021842/cardiac-resynchronization-therapy-in-ischemic-and-non-ischemic-cardiomyopathy
#6
REVIEW
Hisashi Yokoshiki, Hirofumi Mitsuyama, Masaya Watanabe, Takeshi Mitsuhashi, Akihiko Shimizu
Cardiac resynchronization therapy (CRT) using a biventricular pacing system has been an effective therapeutic strategy in patients with symptomatic heart failure with a reduced left ventricular ejection fraction (LVEF) of 35% or less and a QRS duration of 130 ms or more. The etiology of heart failure can be classified as either ischemic or non-ischemic cardiomyopathy. Ischemic etiology of patients receiving CRT is prevalent predominantly in North America, moderately in Europe, and less so in Japan. CRT reduces mortality similarly in both ischemic and non-ischemic cardiomyopathy, whereas reverse structural left ventricular remodeling occurs more favorably in non-ischemic cardiomyopathy...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29020984/fully-digital-data-processing-during-cardiovascular-implantable-electronic-device-follow-up-in-a-high-volume-tertiary-center
#7
Ingo Staudacher, Asha Roy Nalpathamkalam, Lorenz Uhlmann, Claudius Illg, Sebastian Seehausen, Mohammadreza Akhavanpoor, Anke Buchauer, Nicolas Geis, Patrick Lugenbiel, Patrick A Schweizer, Panagiotis Xynogalos, Maura M Zylla, Eberhard Scholz, Edgar Zitron, Hugo A Katus, Dierk Thomas
BACKGROUND: Increasing numbers of patients with cardiovascular implantable electronic devices (CIEDs) and limited follow-up capacities highlight unmet challenges in clinical electrophysiology. Integrated software (MediConnect(®)) enabling fully digital processing of device interrogation data has been commercially developed to facilitate follow-up visits. We sought to assess feasibility of fully digital data processing (FDDP) during ambulatory device follow-up in a high-volume tertiary hospital to provide guidance for future users of FDDP software...
October 11, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/29016821/super-response-to-cardiac-resynchronization-therapy-reduces-appropriate-implantable-cardioverter-defibrillator-therapy
#8
Ammar M Killu, Anna Mazo, Avishay Grupper, Malini Madhavan, Tracy Webster, Kelly L Brooke, David O Hodge, Samuel J Asirvatham, Paul A Friedman, Michael Glikson, Yong-Mei Cha
Aims: To determine the frequency of implantable cardioverter defibrillator (ICD) therapy following cardiac resynchronization therapy (CRT-D) implantation in super and non-super responders and whether greater improvement in left ventricular (LV) function after CRT is associated with a reduced burden in ICD therapy. Methods and results: This is a two-centre, retrospective study between January 2002 and September 2011. Patients were classified as non-super responders and super-responders based on the post-CRT ejection fraction (EF) of < 50% and ≥50%, respectively...
August 4, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016784/sex-differences-in-outcomes-of-primary-prevention-implantable-cardioverter-defibrillator-therapy-combined-registry-data-from-eleven-european-countries
#9
Christian Sticherling, Barbora Arendacka, Jesper Hastrup Svendsen, Sofieke Wijers, Tim Friede, Jochem Stockinger, Michael Dommasch, Bela Merkely, Rik Willems, Andrzej Lubinski, Michael Scharfe, Frieder Braunschweig, Martin Svetlosak, Christine S Zürn, Heikki Huikuri, Panagiota Flevari, Caspar Lund-Andersen, Beat A Schaer, Anton E Tuinenburg, Leonard Bergau, Georg Schmidt, Gabor Szeplaki, Bert Vanderberk, Emilia Kowalczyk, Christian Eick, Juhani Juntilla, David Conen, Markus Zabel
Aims: Therapy with an implantable cardioverter defibrillator (ICD) is established for the prevention of sudden cardiac death (SCD) in high risk patients. We aimed to determine the effectiveness of primary prevention ICD therapy by analysing registry data from 14 centres in 11 European countries compiled between 2002 and 2014, with emphasis on outcomes in women who have been underrepresented in all trials. Methods and results: Retrospective data of 14 local registries of primary prevention ICD implantations between 2002 and 2014 were compiled in a central database...
June 28, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016777/long-term-impact-of-intrathoracic-impedance-findings-on-survival-and-heart-failure-hospitalizations-after-cardiac-resynchronization-therapy-in-icd-registry-patients
#10
Jason R Brown, Alvaro Alonso, Eduardo N Warman, Kenneth C Bilchick
Aims: To determine adjusted associations among OptiVol® threshold crossings, long-term survival, and hospitalizations among heart failure (HF) patients with Medicare coverage in the United States. Methods and results: A cohort with OptiVol®-enabled cardiac resynchronization therapy defibrillators (CRT-D) devices from the Implantable Cardioverter Defibrillator Registry was linked to both Medicare claims/summary data and Medtronic's CareLink® Network data. An extended multivariable Cox model was used to analyse associations among OptiVol® threshold crossings (treated as time-dependent covariates), mortality, and HF-related hospitalizations (HFH)...
August 25, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016772/do-women-benefit-equally-as-men-from-the-primary-prevention-implantable-cardioverter-defibrillator
#11
Sérgio Barra, Rui Providência, Serge Boveda, Kumar Narayanan, Munmohan Virdee, Eloi Marijon, Sharad Agarwal
Women traditionally have been and are still underrepresented in research in many important areas of cardiology, and guideline recommendations which also encompass women are mostly based on research conducted predominantly in men. However, there is plausible cause to believe that sex may have a potential influence on the benefit derived from the implantable cardioverter-defibrillators (ICD), alone or in association with cardiac resynchronization therapy. We assessed the possible relationship between sex and outcome with ICD implantation in the setting of primary prevention, by pooling the results of MUSTT, MADIT-II, DEFINITE, COMPANION, SCD-HeFT and DANISH trials in a meta-analysis...
July 18, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016747/five-year-trends-2008-2012-in-cardiac-implantable-electrical-device-utilization-in-five-european-nations-a-case-study-in-cross-country-comparisons-using-administrative-databases
#12
Helen Banks, Aleksandra Torbica, Cinzia Valzania, Yauheniya Varabyova, Valentina Prevolnik Rupel, Rod S Taylor, Theresa Hunger, Simon Walker, Giuseppe Boriani, Giovanni Fattore
Aims: Common methodologies for analysis of analogous data sets are needed for international comparisons of treatment and outcomes. This study tests using administrative hospital discharge (HD) databases in five European countries to investigate variation/trends in pacemaker (PM) and implantable cardioverter defibrillator (ICD) implant rates in terms of patient characteristics/management, device subtype, and initial implantation vs. replacement, and compares findings with existing literature and European Heart Rhythm Association (EHRA) reports...
June 14, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28990947/ablation-of-epicardial-premature-ventricular-contractions-in-a-patient-with-ischemic-cardiomyopathy-and-implementation-of-cardiac-resynchronization-therapy-in-the-same-procedure
#13
Veysel Kutay Vurgun, Başar Candemir, Ali Timuçin Altın, Ömer Akyürek
Premature ventricular contractions (PVCs) can cause clinical deterioration in patients with heart failure and increase the frequency of shocks delivered by an implantable cardioverter defibrillator (ICD). Epicardial PVC/ventricular tachycardia (VT) is seen less often in ischemic cardiomyopathy. Radiofrequency catheter ablation is the most effective treatment option for the management of PVC/VT and can improve cardiac function. Presently described is a patient with ischemic cardiomyopathy and frequent PVCs and VT runs with multiple ICD therapies who was treated with simultaneous radiofrequency catheter ablation in the anterior interventricular vein and cardiac resynchronization therapy defibrillator upgrade in the same procedure...
October 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28975636/combining-electromagnetic-navigation-and-3-d-mapping-to-reduce-fluoroscopy-time-and-achieve-optimal-crt-response
#14
Umberto Barbero, Carlo Budano, Pier Giorgio Golzio, Davide Castagno, Fiorenzo Gaita
Implantation of cardiac resynchronization therapy (CRT) devices can be challenging, time consuming, and associated with high-dose X-Ray exposure. We present the technique in which an electromagnetic navigation system (MediGuideTM, St. Jude Medical) and an electro-anatomical three-dimensional mapping system (EnSite NavX, St Jude Medical) are usefully combined for implanting ICD-CRT devices with strong reduction of X-ray exposure, and for targeting the most delayed regions in the activation maps avoiding scars for optimal CRT response...
October 4, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28966312/risk-stratification-of-future-left-ventricular-dysfunction-for-patients-with-indications-for-right-ventricular-pacing-due-to-bradycardia
#15
Junichi Ooka, Hidekazu Tanaka, Yutaka Hatani, Keiko Hatazawa, Hiroki Matsuzoe, Hiroyuki Shimoura, Hiroyuki Sano, Takuma Sawa, Yoshiki Motoji, Yasuhide Mochizuki, Keiko Ryo-Koriyama, Kensuke Matsumoto, Koji Fukuzawa, Ken-Ichi Hirata
Although right ventricular (RV) pacing is the only effective treatment for patients with symptomatic bradycardia, it creates left ventricular (LV) dyssynchrony, which can induce LV dysfunction and heart failure. The current criterion for consideration of cardiac resynchronization therapy (CRT) is LV ejection fraction (LVEF) ≤ 35%, but indication for CRT in patients required for RV pacing with LVEF > 35% remains unclear.We studied 40 patients, all LVEF ≥ 35%, who had undergone implantable cardioverter-defibrillator implantation with RV pacing < 5%...
September 30, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28960867/clinical-presentation-at-first-heart-failure-hospitalization-does-not-predict-recurrent-heart-failure-admission
#16
Annamaria Kosztin, Jason Costa, Arthur J Moss, Yitschak Biton, Vivien Klaudia Nagy, Scott D Solomon, Laszlo Geller, Scott McNitt, Bronislava Polonsky, Bela Merkely, Valentina Kutyifa
AIMS: There are limited data on whether clinical presentation at first heart failure (HF) hospitalization predicts recurrent HF events. We aimed to assess predictors of recurrent HF hospitalizations in mild HF patients with an implantable cardioverter defibrillator or cardiac resynchronization therapy with defibrillator. METHODS AND RESULTS: Data on HF hospitalizations were prospectively collected for patients enrolled in MADIT-CRT. Predictors of recurrent HF hospitalization (HF2) after the first HF hospitalization were assessed using Cox proportional hazards regression models including baseline covariates and clinical presentation or management at first HF hospitalization...
June 17, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28960673/screening-for-heart-transplantation-and-left-ventricular-assist-system-results-from-the-screening-for-advanced-heart-failure-treatment-see-hf-study
#17
Lars H Lund, Jean-Noel Trochu, Bart Meyns, Kadir Caliskan, Steven Shaw, Jan D Schmitto, David Schibilsky, Laura Damme, Jerry Heatley, Finn Gustafsson
BACKGROUND: Heart transplantation (HTx) and implantable left ventricular assist systems (LVAS) improve outcomes in advanced heart failure but may be underutilized. We hypothesized that screening can identify appropriate candidates. METHODS AND RESULTS: The ScrEEning for advanced Heart Failure treatment (SEE-HF) study was a multicentre prospective study screening patients with existing cardiac resynchronization therapy (CRT) and/or implantable cardioverter-defibrillator (ICD) for ejection fraction ≤40% and New York Heart Association (NYHA) class III-IV, and subsequently for guideline-based HTx and LVAS indication...
September 27, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28957879/perioperative-management-of-cardiac-rhythm-assist-devices-in-ambulatory-surgery-and-nonoperating-room-anesthesia
#18
Lovkesh Arora, Chakradhari Inampudi
PURPOSE OF REVIEW: Patients with cardiac implantable electronic devices (CIEDs) frequently undergo various surgical procedures and in the past perioperative management involved only placing magnet over the device. New programming features, development of implantable cardiac defibrillator (ICD), cardiac resynchronization therapy, and increasing complexity of the operating room equipment have led to new sources of electromagnetic interference (EMI). A comprehensive understanding of the CIED is necessary to provide a timely and optimal care to the patients...
September 27, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28948481/device-management-in-heart-failure
#19
REVIEW
Brett G Angel, Heath Saltzman, Luke S Kusmirek
PURPOSE OF REVIEW: Medical devices have become an integral part of comprehensive heart failure management. Not all heart failure patients, however, accrue benefit from every new device, and even with extensive practice guidelines, this remains an evolving field. RECENT FINDINGS: The addition of implantable devices, like internal cardioverter defibrillators (ICDs), and novel pacing technologies, including cardiac resynchronization therapy (CRT), have helped to compliment goal-directed medical therapy and positively impact prognosis in multiple high-quality clinical trials...
September 25, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28947249/impact-of-tachyarrhythmia-detection-rate-and-time-from-detection-to-shock-on-outcomes-in-nationwide-us-practice
#20
MULTICENTER STUDY
Jonathan P Piccini, Prashanthan Sanders, Riddhi Shah, Greg Roberts, Edward Karst, Mintu P Turakhia
Although higher detection rates and delayed detection improve survival in implantable cardioverter defibrillator clinical trials, their effectiveness in clinical practice has limited validation. To evaluate the effectiveness of programming strategies for reducing shocks and mortality, we conducted a nationwide assessment of patients with implantable cardioverter defibrillators or cardiac resynchronization therapy defibrillators with linked remote monitoring data. We categorized patients based on the presence or absence of high rate detection and delayed detection: higher rate delayed detection (HRDD), higher rate early detection (HRED), lower rate delayed detection (LRDD), and lower rate early detection (LRED)...
October 15, 2017: American Journal of Cardiology
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