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https://www.readbyqxmd.com/read/29665869/review-risks-of-disease-transmission-through-semen-in-cattle
#1
M D Givens
The purpose of this paper is to review scientific evidence concerning pathogens that could potentially be transmitted via bovine semen. As a result of a careful analysis of the characteristics of infections that may cause transmission of disease through semen, effective control procedures can be identified that provide minimal constraint to the introduction of new bulls into herds for natural breeding and importation of valuable novel genetics through artificial insemination. The potential for transmission through bovine semen and corresponding effective control procedures are described for bovine herpesvirus 1, bovine viral diarrhea virus, bovine leukemia virus, lumpy skin disease virus, bluetongue virus, foot-and-mouth disease virus, and Schmallenberg virus...
April 18, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29660299/infection-induced-thrombin-production-a-potential-novel-mechanism-for-preterm-premature-rupture-of-membranes-pprom
#2
Liping Feng, Terrence K Allen, William P Marinello, Amy P Murtha
BACKGROUND: Preterm premature rupture of membranes (PPROM) is a leading contributor to maternal and neonatal morbidity and mortality. Epidemiologic and experimental studies have demonstrated that thrombin causes fetal membrane weakening and subsequently PPROM. Although blood is suspected as the likely source of thrombin in fetal membranes and amniotic fluid of patients with PPROM, this has not been proven. Ureaplasma Parvum (U. parvum) is emerging as a pathogen involved in prematurity, including PPROM, but until now, prothrombin production directly induced by bacteria in fetal membranes has not been described...
April 13, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29658200/detection-of-ureaplasma-species-by-a-semi-quantitative-pcr-test-in-urine-samples-can-it-predict-clinical-significance
#3
Merav Strauss, Raul Colodner, Dana Sagas, Azmi Adawi, Hanna Edelstein, Bibiana Chazan
BACKGROUND: Ureaplasma species (Usp) are the most prevalent genital Mycoplasma isolated from the urogenital tract of both men and women. Usp may be commensals in the genital tract but may also be contributors to a number of pathological conditions of the genital tract. Because they can also just colonize the genital tract of healthy people, their pathogenic role can be difficult to prove. OBJECTIVES: The aim of the study was to evaluate the efficacy of a quantitative polymerase chain reaction (qPCR) method for the discrimination between infection and colonization by measuring prevalence of Usp in asymptomatic versus symptomatic patients...
January 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29629645/development-and-application-of-two-multiplex-real-time-pcr-assays-for-detection-and-speciation-of-bacterial-pathogens-in-the-koala
#4
Lyndal S Hulse, Danica Hickey, Jessica M Mitchell, Kenneth W Beagley, William Ellis, Stephen D Johnston
Infectious diseases have contributed to the decline in the health of koala ( Phascolarctos cinereus) populations in the wild in some regions of Australia. Herein we report the development and validation of 2 multiplex real-time PCR (rtPCR) panels for the simultaneous detection of Mycoplasma spp., Ureaplasma spp., Bordetella bronchiseptica, and Chlamydia, including speciation and quantification of Chlamydia, in ocular, reproductive, and nasal swab samples in addition to semen and male urogenital and reproductive tissues, from koalas...
April 1, 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29623213/a-case-of-oropharyngeal-ureaplasma-urealyticum-infection-in-a-human-immunodeficiency-virus-positive-bisexual-male-co-infected-with-human-papilloma-virus-and-treponema-pallidum
#5
Nazneen Arif Suri, Sujeesh Sebastian, Deepika Yadav, Neena Khanna, Benu Dhawan
Introduction: Management strategies for sexually transmitted infections (STIs) in their extragenital forms address Neisseria gonorrhoeae and Chlamydia trachomatis alone; whereas increased rates of isolation of other STI agents have been reported from various parts of the world. Their extragenital presence as a reservoir of infection emphasizes the need to screen and treat them at these sites. Case presentation: A 35-year-old human immunodeficiency virus 1 infected bisexual male presented with urethral discharge and multiple ano-genital warts...
March 2018: JMM Case Reports
https://www.readbyqxmd.com/read/29620787/distribution-of-genital-mollicutes-in-the-vaginal-ecosystem-of-women-with-different-clinical-conditions
#6
Claudio Foschi, Melissa Salvo, Antonietta D'Antuono, Valeria Gaspari, Nicoletta Banzola, Roberto Cevenini, Antonella Marangoni
Ureaplasma urelayticum (UU), Ureaplasma parvum (UP), Mycoplasma hominis (MH) and Mycoplasma genitalium (MG) are the most common Mollicutes of the female genital tract. Although many studies have addressed their possible role in the vaginal ecosystem, many aspects remain to be elucidated. The aim of this study was to evaluate the vaginal presence of ureaplasmas/mycoplasmas in women with different clinical conditions. By means of quantitative PCR assays, the prevalence and load of each Mollicute were assessed in different groups of pre-menopausal women: 'healthy' (n=29), women with bacterial vaginosis (BV) (n=21), patients with Chlamydia trachomatis (CT) infection (n=25) and subjects with vulvo-vaginal candidiasis (VVC) (n=23)...
April 5, 2018: New Microbiologica
https://www.readbyqxmd.com/read/29619908/prevalence-of-sexually-transmitted-diseases-in-asymptomatic-renal-transplant-recipients
#7
Mehmet Sarier, Nevgun Sepin Ozen, Hicran Guler, Ibrahim Duman, Yücel Yüksel, Sabri Tekin, Asuman Havva Yavuz, Levent Yucetin, Mine Erdogan Yilmaz
OBJECTIVES: Sexually transmitted diseases, which may be asymptomatic, have the potential to cause serious health problems in renal transplant recipients. The aim of this study was to determine the prevalence of sexually transmitted diseases in sexually active asymptomatic renal transplant patients by using real-time multiplex polymerase chain reaction assays. MATERIALS AND METHODS: This prospective controlled study was conducted between November 2016 and January 2017 in our hospital...
April 4, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29564244/prevalence-of-mycoplasma-genitalium-and-other-sexually-transmitted-pathogens-among-high-risk-individuals-in-greece
#8
Paraskevi Chra, Joseph Papaparaskevas, Eleni Papadogeorgaki, George Panos, Michalis Leontsinidis, George Arsenis, Athanassios Tsakris
Background: The aim of the present study was to determine the prevalence of Mycoplasma genitalium (MG) infection among individuals at high risk for sexually-transmitted diseases (STDs) at a major urban STD clinic in Athens, in view of the lack of data pertaining to this infection in Greece. Methods: Urethral and cervical samples from 176 individuals consecutively attending the clinic and agreeing to participate were prospectively collected and tested for MG infection using conventional PCR and TaqMan Real-Time PCR...
March 2018: Germs
https://www.readbyqxmd.com/read/29558521/ureaplasma-isolates-stimulate-pro-inflammatory-cc-chemokines-and-matrix-metalloproteinase-9-in-neonatal-and-adult-monocytes
#9
Kirsten Glaser, Christine Silwedel, Markus Fehrholz, Birgit Henrich, Ana Maria Waaga-Gasser, Heike Claus, Christian P Speer
Being generally regarded as commensal bacteria, the pro-inflammatory capacity of Ureaplasma species has long been debated. Recently, we confirmed Ureaplasma-driven pro-inflammatory cytokine responses and a disturbance of cytokine equilibrium in primary human monocytes in vitro. The present study addressed the expression of CC chemokines and matrix metalloproteinase-9 (MMP-9) in purified term neonatal and adult monocytes stimulated with serovar 8 of Ureaplasma urealyticum (Uu) and serovar 3 of U. parvum (Up)...
2018: PloS One
https://www.readbyqxmd.com/read/29556819/phylogenetic-framework-for-the-phylum-tenericutes-based-on-genome-sequence-data-proposal-for-the-creation-of-a-new-order-mycoplasmoidales-ord-nov-containing-two-new-families-mycoplasmoidaceae-fam-nov-and-metamycoplasmataceae-fam-nov-harbouring-eperythrozoon
#10
Radhey S Gupta, Sahil Sawnani, Mobolaji Adeolu, Seema Alnajar, Aharon Oren
The genus Mycoplasma, including species earlier classified in the genera Eperythrozoon and Haemobartonella, contains ~ 120 species and constitutes an extensively polyphyletic assemblage of bacteria within the phylum Tenericutes. Due to their small genome sizes and lack of unique characteristics, the relationships among the mycoplasmas/Tenericutes are not reliably discerned. Using genome sequences for 140 Tenericutes, their evolutionary relationships were examined using multiple independent approaches. Phylogenomic trees were constructed for 63 conserved proteins, 45 ribosomal proteins, three main subunits of RNA polymerase and 16S rRNA gene sequences...
March 20, 2018: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29553074/-validation-of-the-kit-for-detecting-mycoplasma-genitalium-from-the-male-urethritis
#11
Ryoichi Hamasuna, Masahiro Matsumoto, Phuong Thi LE, Naohiro Fujimoto, Tetsuro Matsumoto
Mycoplasma genitalium is one of the pathogenic microorganisms in male urethritis as a sexually transmitted infection (STI). M.genitalium is detected in the urine specimens of 15-25% male patients with urethritis. The emergence of macrolide- or fluoroquinolone-resistant M.genitalium has become a serious problem in the treatment of male urethritis worldwide, but there is no commercial-based detecting kits accepted by the national insurance in Japan. In this study, we tested the validity of a molecular kit for detecting seven microorganisms related to STI (Anyplex™ II STI-7 Detection which detects Neisseria gonorrhoeae, Chlamydia trachomatis, M...
2018: Journal of UOEH
https://www.readbyqxmd.com/read/29524791/polybacterial-stimulation-suggests-discrete-il-6-il-6r-signaling-in-human-fetal-membranes-potential-implications-on-il-6-bioactivity
#12
Nathalia Mayumi Noda-Nicolau, Jossimara Polettini, Márcia Guimarães da Silva, Morgan R Peltier, Ramkumar Menon
The polybacterial invasion of the amniotic cavity and risk of preterm birth is often due to cervicovaginal bacteria such as genital mycoplasmas (Mycoplasma hominis and Ureaplasma urealyticum) and Gardnerella vaginalis. The most studied biomarker associated with preterm birth is interleukin-6 (IL-6), a pleiotropic cytokine that performs different functions based on classical or trans-signaling mechanisms. This study evaluated the changes in IL-6 and IL-6 function associated accessory molecules by human fetal membranes to determine the functional availability of IL-6 assessment in an in vitro model of polybacterial infection...
March 2, 2018: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29520664/association-between-genital-mycoplasmas-infection-and-human-papillomavirus-infection-abnormal-cervical-cytopathology-and-cervical-cancer-a-systematic-review-and-meta-analysis
#13
REVIEW
Hui Ye, Tiange Song, Xi Zeng, Lin Li, Minmin Hou, Mingrong Xi
BACKGROUND: Some studies demonstrated that female genital mycoplasmas play important roles in human papillomavirus (HPV) infection, abnormal cervical cytopathology, and cervical cancer. However, those results remained inconclusive. We aimed to perform a systematic review and meta-analysis to investigate the association between female genital mycoplasmas and those disorders. METHODS: Computerized databases were comprehensively searched before 26 January 2017. Pooled odd radios (ORs) and correlative 95% confidence intervals (CIs) were adopted to evaluate the strength of association...
March 8, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29498739/prevalence-and-antimicrobial-resistance-of-genital-mollicutes-in-italy-over-a-two-year-period
#14
Claudio Foschi, Melissa Salvo, Silvia Galli, Alessandra Moroni, Roberto Cevenini, Antonella Marangoni
Knowledge of the prevalence and antimicrobial susceptibility of genital Mollicutes is crucial to offer guidelines for empirical treatments. The aim of this study was to investigate the prevalence and the resistance profile of Mycoplasma hominis (MH) and Ureaplasma urealyticum/Ureaplasma parvum (UU/UP) in genital samples over a two-year period in Bologna, Italy. From January 2015 to December 2016, data on all the subjects providing uro-genital specimens for Mollicutes detection by culture were analyzed. A total of 4660 subjects (84...
March 2, 2018: New Microbiologica
https://www.readbyqxmd.com/read/29477653/the-diagnosis-of-chronic-endometritis-in-infertile-asymptomatic-women-a-comparative-study-of-histology-microbial-cultures-hysteroscopy-and-molecular-microbiology
#15
Inmaculada Moreno, Ettore Cicinelli, Iolanda Garcia-Grau, Marta Gonzalez, Davide Bau, Felipe Vilella, Dominique DE Ziegler, Leonardo Resta, Diana Valbuena, Carlos Simon
BACKGROUND: Chronic endometritis is a persistent inflammation of the endometrial mucosa caused by bacterial pathogens such as Enterobacteriaceae, Enterococcus, Streptococcus, Staphylococcus, Mycoplasma, and Ureaplasma. Although chronic endometritis can be asymptomatic, it is found in up to 40% of infertile patients and is responsible for repeated implantation failure and recurrent miscarriage. Diagnosis of chronic endometritis is based on hysteroscopy of the uterine cavity, endometrial biopsy with plasma cells being identified histologically, while specific treatment is determined based on microbial culture...
February 22, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29455108/ureaplasma-isolates-differentially-modulate-growth-factors-and-cell-adhesion-molecules-in-human-neonatal-and-adult-monocytes
#16
Kirsten Glaser, Christine Silwedel, Ana Maria Waaga-Gasser, Birgit Henrich, Markus Fehrholz, Heike Claus, Christian P Speer
Generally regarded as commensal bacteria, the pathogenicity of Ureaplasma has often been considered low. Controversy remains concerning the clinical relevance of Ureaplasma infection in the pathogenesis of inflammation-related morbidities. Recently, we demonstrated Ureaplasma-driven pro-inflammatory cytokine responses in human monocytes in vitro. We hypothesized that Ureaplasma may induce further inflammatory mediators. Using qRT-PCR and multi-analyte immunoassay, we assessed the expression of granulocyte-colony stimulating factor (G-CSF), vascular endothelial growth factor (VEGF), intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) in term neonatal and adult monocytes exposed to Ureaplasma urealyticum serovar 8 (Uu8) and U...
February 15, 2018: Cytokine
https://www.readbyqxmd.com/read/29428309/mycoplasma-genitalium-can-modulate-the-local-immune-response-in-patients-with-endometriosis
#17
Guilherme B Campos, Lucas M Marques, Izadora S Rezende, Maysa S Barbosa, Mauricio S Abrão, Jorge Timenetsky
OBJECTIVE: To detect Mollicutes in women with endometriosis and healthy peritoneal tissues and evaluate the participation of these bacteria in the immune response during endometriosis. DESIGN: Cross-sectional study. SETTING: University hospitals. PATIENT (S): Women with endometriosis (n = 73) and without endometriosis (n = 31). INTERVENTION(S): Endocervical swabs, peritoneal fluid, and biopsied lesions of endometriosis of women with endometriosis (study group) and healthy peritoneal tissues (control group) were collected during surgery...
February 7, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29396486/in-vivo-microbiome-and-associated-immune-markers-new-insights-into-the-pathogenesis-of-vaginal-dysbiosis
#18
Giuseppina Campisciano, Nunzia Zanotta, Danilo Licastro, Francesco De Seta, Manola Comar
The microbiota fulfils a key role in the training and function of the immune system, which contributes to the symbiosis between the host and complex microbial communities. In this study, we characterized the interplay between vaginal bacteria and local immune mediators during dysbiosis in selected women of reproductive age who were grouped according to Nugent's criteria. The abundance of Gardnerella vaginalis and Bifidobacterium breve was increased in the intermediate dysbiotic status, while the presence of a plethora of non-resident bacteria characterized the group with overt vaginosis...
February 2, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29376609/-concomitant-urogenital-infections-in-men
#19
O A Chubukova, V V Shkarin
The article presents possible combinations of urogenital infections of various etiologies and some pathogenetic, clinical and epidemiological features, and issues of epidemiological surveillance for co-infection. The authors describe in detail combinations with each other and with other diseases of such pathogens as Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis. They also focus on the problem of co-occurrence of human papillomavirus (HPV) with other urogenital pathogens...
December 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29376018/effects-of-infections-with-five-sexually-transmitted-pathogens-on-sperm-quality
#20
Sung Jae Kim, Doo-Jin Paik, Joong Shik Lee, Hyo Serk Lee, Ju Tae Seo, Mi Seon Jeong, Jae-Ho Lee, Dong Wook Park, Sangchul Han, Yoo Kyung Lee, Ki Heon Lee, In Ho Lee, Kyeong A So, Seon Ah Kim, Juree Kim, Tae Jin Kim
Objective: This study investigated the prevalence of infections with human papillomavirus, Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma hominis, and Mycoplasma genitalium in the semen of Korean infertile couples and their associations with sperm quality. Methods: Semen specimens were collected from 400 men who underwent a fertility evaluation. Infection with above five pathogens was assessed in each specimen. Sperm quality was compared in the pathogen-infected group and the non-infected group...
December 2017: Clinical and Experimental Reproductive Medicine
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