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Atypical mycobacteriosis

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https://www.readbyqxmd.com/read/27728916/lobar-collapse-therapy-using-endobronchial-valves-as-a-new-complementary-approach-to-treat-cavities-in-multidrug-resistant-tuberculosis-and-difficult-to-treat-tuberculosis-a-case-series
#1
Lorenzo Corbetta, Ariela Tofani, Flavio Montinaro, Lucio Michieletto, Loris Ceron, Chiara Moroni, Pier Giorgio Rogasi
BACKGROUND: The poor treatment outcomes of multidrug-resistant tuberculosis (TB) and the emergence of extensively drug-resistant TB and extremely and totally drug-resistant TB highlight the urgent need for new antituberculous drugs and other adjuvant treatment approaches. OBJECTIVES: We have treated cavitary tuberculosis by the application of endobronchial one-way valves (Zephyr®; Pulmonx Inc., Redwood City, Calif., USA) to induce lobar volume reduction as an adjunct to drug treatment...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27098613/atypical-mycobacteriosis-involving-parotid-and-para-retropharyngeal-spaces
#2
Marco Bonali, Francesco Mattioli, Matteo Alicandri-Ciufelli, Livio Presutti
The incidence of retro-parapharyngeal localization of cervical adenitis due to non-tuberculous mycobacteria is very rare. We present a case of an 18-months-old child with an involvement of parapharyngeal and retropharyngeal areas, right parotid and submandibular regions by atypical mycobacteriosis in the CT and MRI scan. The masses were surgically removed and the frozen-section histological exam upheld their atypical mycobacterial origin.
April 20, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/26651929/-mycobacterium-avium-tumoral-infection-mimicking-a-lung-adenocarcinoma-a-potential-diagnostic-pitfall
#3
A A Fiogbe, G Liistro, D Hoton, T Pieters
INTRODUCTION: The incidence of atypical mycobacterial infection in Europe is estimated at one case per 100,000 persons/year. Despite the low incidence of Mycobacterium avium infection, it can result in a nodular lesion simulating lung cancer. We report a case of atypical mycobacteriosis, mimicking lung cancer, which led to a lobectomy. CASE REPORT: It was a right pulmonary upper lobe nodule found in a 63-year-old COPD patient, partially nephrectomized for renal carcinoma, and weekly treated by methotrexate for rheumatoid arthritis...
April 2016: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/26329680/leukoencephalopathy-resolution-after-atypical-mycobacterial-treatment-a-case-report
#4
Marcos C B Oliveira, Douglas Kazutoshi Sato, Herval R Soares-Neto, Leandro T Lucato, Dagoberto Callegaro, Ricardo Nitrini, Raphael S S Medeiros, Tatsuro Misu, Kazuo Fujihara, Luiz H Castro
BACKGROUND: Association of leukoencephalopathy and atypical mycobacteriosis has been rarely reported. We present a case that is relevant for its unusual presentation and because it may shed further light on the pathogenic mechanisms underlying reversible encephalopathies. CASE REPORT: We report the case of a Hispanic 64-year-old woman with cognitive decline and extensive leukoencephalopathy. Magnetic resonance imaging revealed white-matter lesions with increased water diffusivity, without blood-brain-barrier disruption...
2015: BMC Neurology
https://www.readbyqxmd.com/read/26312697/disseminated-cutaneous-atypical-mycobacteriosis-by-m-chelonae-after-sclerotherapy-of-varicose-veins-in-a-immunocompetent-patient-a-case-report
#5
Nathalia Dias Negrão Murback, Minoru German Higa Júnior, Maurício Antônio Pompílio, Eunice Stella Jardim Cury, Gunter Hans Filho, Luiz Carlos Takita
Atypical mycobacteria are saprophytic organisms not transmitted from person to person, which affect mainly immunosuppressed but also immunocompetent individuals. We present a case of atypical mycobacteriosis after a vascular procedure, with widespread cutaneous lesions associated with polyarthralgia. Mycobacterium chelonae was identified by the polymerase chain reaction (PCR) method. The patient showed improvement after treatment with three antibiotics. Mycobacterium chelonae causes skin lesions after invasive procedures...
May 2015: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/26049664/pancreatic-atypical-mycobacteriosis-evaluated-by-18-f-fdg-pet-ct
#6
G Treglia, L Ceriani, L Giovanella
No abstract text is available yet for this article.
January 2016: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/26038402/naturally-acquired-mycobacterium-tuberculosis-complex-in-laboratory-pig-tailed-macaques
#7
Gregory A Engel, Alicia K Wilbur, Andrew Westmark, Dara Horn, Jordan Johnson, Lisa Jones-Engel
Here we present a case series from a primate research facility. The index case, a 4-year-old pig-tailed macaque (Macaca nemestrina) experimentally infected with chimeric simian-human immunodeficiency virus (SHIVSF162 P4), developed weight loss and was euthanized. Based on necropsy results the animal was diagnosed with opportunistic atypical mycobacteriosis associated with simian AIDS (SAIDS). Subsequently, tissues from the index animal, as well as tissues and oral mucosal swabs from six SHIV-infected contacts, were analyzed using molecular methods and found to contain nucleic acid sequences characteristic of Mycobacterium tuberculosis complex (MTBC)...
October 2012: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/25992258/concurrent-atypical-diffused-tuberculosis-and-macrorhabdosis-in-a-canary-serinus-canaria
#8
Seyed Ahmad Madani, Mohammad Reza Haddad-Marandi, Fatemeh Arabkhazaeli
A dead canary from a mixed species zoological garden was presented for diagnostic necropsy. Cachexia with prominent atrophy of pectoral muscles, yellowish brown discoloration of the liver and kidney, dark brown to black intestinal contents and moderate proventricular dilatation with some degree of catarrhal gastritis were the significant macroscopic findings. Parenchymatous organs like the liver, the spleen, the lung and the kidneys were extremely affected by massive diffuse necrosis and heavy infiltration of mononuclear inflammatory cells, histopathologically...
2015: Veterinary Research Forum
https://www.readbyqxmd.com/read/25676343/mutations-in-genes-underlying-atypical-familial-mycobacteriosis-are-not-found-in-tuberculosis-patients-from-siberian-populations
#9
Alexey A Rudko, Anna F Garaeva, Elena Yu Bragina, Nadezda P Babushkina, Olga V Kolokolova, Olga N Lipaenkova, Valery P Puzyrev, Maxim B Freidin
OBJECTIVES: Atypical familial mycobacteriosis (AFM, OMIM #209950) is caused by mutations in genes regulating IL12/IFNG pathway. Some of the mutations exhibit incomplete penetrance, and they have been proposed to be involved in the common (polygenic) predisposition to tuberculosis (TB). We set out to test this hypothesis in two populations from Siberian region of Russia with high prevalence of TB. MATERIAL AND METHODS: The prevalence of twelve mutations in IL12/IFNG pathway genes of were analysed in 331 Russians and 238 Tuvinians TB patients and in 279 healthy Russians and 265 healthy Tuvinians...
March 2015: Tuberculosis
https://www.readbyqxmd.com/read/25334365/disseminated-mycobacterium-abscessus-in-a-lung-transplant-patient-manifesting-as-a-chest-wall-mass-and-acute-renal-failure
#10
Ahmad Goodarzi, Neeraj Sinha, Soma Jyothula, Babith Mankidy, Thomas Kaleekal, Victor Fainstein
Miscellaneous Case Report Posters IIISESSION TYPE: Affiliate Case Report PosterPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Atypical Mycobacterial disease is common in lung transplant, however only a few cases of Mycobacterium abscessus in lung transplant recipients have been described, mainly in cystic fibrosis.Disseminated M.abscessus is uncommon and difficult to treat.Here, We report a rare case of lung transplant patient with disseminated M.abscessus involving skin, blood and urinary tract...
October 1, 2014: Chest
https://www.readbyqxmd.com/read/24990793/atypical-mycobacteriosis-in-children-a-diagnostic-and-therapeutic-challenge
#11
C M C Deichmueller, K Emmanouil, H-J Welkoborsky
Atypical mycobacteriosis (AM) is a rare disease, which is caused by an infection with mycobacteria other than tuberculosis (MOTT). In children, the cervical lymph nodes are frequently affected. MOTT are a pathogen or facultative pathogen environmental germs, which can affect otherwise healthy individuals. The diagnostic and therapeutic management is often challenging. Currently, there are only few data published about the systematic investigation and therapy of children with AM. In a retrospective study, 29 children with AM were evaluated...
September 2015: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/24795050/morphological-manifestations-of-the-atypical-mycobacteriosis-caused-by-nontuberculous-mycobacteria-in-the-hiv-infected-patients
#12
Marina U Mayskaya, Tatiana F Otten, Boris M Ariel, Elena P Fedotova, Robert L Hunter, Ruslan A Nasyrov
Infection with atypical mycobacteria (MAC) is a well-known complication of AIDS that typically occurs only in people with advanced immunodeficiency. We studied tissues from 13 patients with HIV and atypical mycobacterial infection who died in St Petersburg Russia from 2009-2012. Three patterns of disease were identified that suggest effects of host resistance. The first pattern was in people paucibacillary disease. They had positive blood cultures and histologic changes consistent with mycobacterial infection, but no stainable acid fast bacilli (AFB)...
2014: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/24633375/-management-of-atypical-cervical-mycobacteriosis-in-childhood
#13
REVIEW
T van Bremen, E Biesinger, F Göke, S Keiner, F Bootz, A Schröck
Atypical mycobacteriosis is a rare cause of cervical lymphadenitis that most frequently affects immunoincompetent children between the ages of 12 months and 5 years. The typical clinical manifestation is a painless unilateral cervical mass. The nonspecific clinical symptoms and laboratory parameters complicate diagnosis and, therefore, therapeutic management. Various therapeutic options, including surgery, antimycobacterial drug therapy and wait-and-scan approaches are discussed in the literature. Complete surgical excision has become the established treatment of choice...
April 2014: HNO
https://www.readbyqxmd.com/read/24388366/nine-pulmonary-aspiration-syndrome-cases-of-atypical-clinical-presentation-in-which-the-final-diagnosis-was-obtained-by-histological-examinations
#14
Masahiro Shimada, Shinji Teramoto, Hirotoshi Matsui, Atsuhisa Tamura, Shinobu Akagawa, Ken Ohta, Akira Hebisawa
BACKGROUND: While pulmonary aspiration syndrome (PAS) is primarily clinically diagnosed, atypical PAS cases can be misdiagnosed clinically and are more accurately diagnosed histologically. To elucidate clinicopathological features of these rare cases, we examined PAS cases determined by histological examination of transbronchial lung biopsy (TBLB) specimens. METHODS: Of 6105 TBLB cases investigated from 1990 to 2007, 11 were diagnosed as PAS based on histology. Of these, we examined 9 records in detail, as the medical records for 2 cases were unavailable...
January 2014: Respiratory Investigation
https://www.readbyqxmd.com/read/24383837/atypical-mycobacteriosis-in-two-patients-with-rheumatoid-arthritis
#15
T Origuchi, K Migita, A Kawakami, S Yamasaki, A Hida, K Shibatomi, H Ida, Y Kawabe, K Eguchi
Abstract We report two cases of rheumatoid arthritis (RA) with atypical mycobacteriosis. Opportunistic infections are critical complications for rheumatic diseases. The use of steroids or immunosuppressants may increase the risk of opportunistic infections. However, these reports are rare in that they demonstrate atypical mycobacterial infections as complications of RA, even though no immunosuppressive agents were used. We discuss the characteristics of atypical mycobacterial infections of the lung in RA.
March 2002: Modern Rheumatology
https://www.readbyqxmd.com/read/24351623/a-case-of-disseminated-nontuberculous-mycobacteriosis-and-cerebellar-toxoplasmosis-with-autoantibody-to-interferon-%C3%AE
#16
Etsuro Yamaguchi, H Tanaka, Takaaki Fukuoka, Y Ohbayashi, M Sato, T Yokoi
Autoantibody against interferon-γ has recently been associated with a variety of opportunistic infections, particularly among Asians. We report the case of a 64-year-old Japanese woman who suffered from concomitant or sequential infections of the skin, lungs, bronchi, uterus, and bladder with nontuberculous mycobacteriosis, cerebellar toxoplasmosis, measles,herpes zoster, and vulvar herpes. Blood mononuclear cells from the patient displayed intact cytokine production in response to various stimuli and interferon-γ...
2013: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/24247002/cytomegalovirus-disease-in-patients-with-common-variable-immunodeficiency-three-case-reports
#17
Pavlina Kralickova, Eva Mala, Doris Vokurkova, Irena Krcmova, Lenka Pliskova, Vlasta Stepanova, Vladimir Bartos, Vladimir Koblizek, Ilja Tacheci, Jan Bures, Jan Brozik, Jiri Litzman
Common variable immunodeficiency (CVID) is the most frequent clinically relevant primary immunodeficiency and shows enormous heterogeneity in clinical presentation. Despite clinical immunodeficiency, opportunistic infections are not a typical manifestation of CVID. A retrospective study of 32 patients followed up for 335 patient-years was performed to determine the frequency of cytomegalovirus (CMV) disease. Symptomatic CMV infection was documented in 3 CVID patients. Patients No. 1 and 2 suffered from CMV pneumonia, with complications due to atypical mycobacteriosis in patient No...
2014: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/24063108/cutaneous-atypical-mycobacteriosis-in-a-clouded-leopard-neofelis-nebulosa
#18
Shannon N S Cerveny, Michelle E Thompson, Sarah M Corner, Amy K Swinford, Rob L Coke
A 16-yr-old male clouded leopard (Neofelis nebulosa) was presented for lethargy and anorexia. A cutaneous abdominal mass extending from the pubis to just caudal to the xiphoid process was present. A biopsy revealed histologic lesions consistent with an atypical mycobacterial infection consisting of diffuse, severe, pyogranulomatous dermatitis and panniculitis, with clear vacuoles and 3-5 microm, intravacuolar, faintly eosinophilic, filamentous bacilli that stained positively with FiteFaraco modified acid-fast stain...
September 2013: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/23813823/mycobacterioses-in-cats-abcd-guidelines-on-prevention-and-management
#19
REVIEW
Albert Lloret, Katrin Hartmann, Maria Grazia Pennisi, Tim Gruffydd-Jones, Diane Addie, Sándor Belák, Corine Boucraut-Baralon, Herman Egberink, Tadeusz Frymus, Margaret J Hosie, Hans Lutz, Fulvio Marsilio, Karin Möstl, Alan D Radford, Etienne Thiry, Uwe Truyen, Marian C Horzinek
OVERVIEW: Mycobacterial infections are important in humans and animals. Cats can be infected by several Mycobacterium species, which may cause different syndromes, mainly tuberculosis, atypical or non-tuberculous mycobacteriosis and leprosy. In recent years, awareness has increased about how to recognise and confirm these infections. More cases are diagnosed today, which probably means that the disease has escaped detection in the past. INFECTION: Most cases in cats are cutaneous, presenting as nodules in the skin and draining tracts, ulceration and local lymphadenopathy; however, systemic dissemination may also occur...
July 2013: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/23455531/atypical-mycobacteriosis-caused-by-mycobacterium-haemophilum-in-an-immunocompromised-patient-diagnosis-by-18-f-fdg-pet-ct
#20
Silvia Münster, Jozef Zustin, Thorsten Derlin
We report a rare case of atypical mycobacteriosis diagnosed by F-FDG PET/CT. A 28-year-old man with a history of kidney transplantation presented with fever, painful nodular skin lesions, and elevated inflammatory markers. FDG PET/CT demonstrated multiple subcutaneous, cutaneous, and osseous areas of increased tracer uptake. Histopathologic and microbiological evaluation revealed disseminated infection with Mycobacterium haemophilum. FDG PET/CT is a valuable tool for early and correct diagnosis of occult sources of infection in immunocompromised patients...
April 2013: Clinical Nuclear Medicine
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