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https://www.readbyqxmd.com/read/29318414/accuracy-of-pedicle-screw-insertion-by-airo%C3%A2-intraoperative-ct-in-complex-spinal-deformity-assessed-by-a-new-classification-based-on-technical-complexity-of-screw-insertion
#1
S Rajasekaran, Manindra Bhushan, Siddharth Aiyer, Rishi Kanna, Ajoy Prasad Shetty
PURPOSE: To develop a classification based on the technical complexity encountered during pedicle screw insertion and to evaluate the performance of AIRO® CT navigation system based on this classification, in the clinical scenario of complex spinal deformity. MATERIALS AND METHODS: 31 complex spinal deformity correction surgeries were prospectively analyzed for performance of AIRO® mobile CT-based navigation system. Pedicles were classified according to complexity of insertion into five types...
January 9, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29290127/image-guidance-in-transdiscal-fixation-for-high-grade-spondylolisthesis-in-adults-with-correct-spinal-balance
#2
Juan Delgado-Fernández, Paloma Pulido, María Ángeles García-Pallero, Guillermo Blasco, Natalia Frade-Porto, Rafael G Sola
OBJECTIVE Spondylolisthesis is a prevalent spine disease that recent studies estimate could be detected in 9% of the population. High-grade spondylolisthesis (HGS), however, is much less frequent, which makes it difficult to develop a general recommendation for its treatment. Posterior transdiscal fixation was proposed in 1994 for HGS, and the use of spine navigation could make this technique more accessible and reduce the morbidity associated with the procedure. The purpose of this study was to present a case series involving adult patients with HGS and correct spinal alignment who were treated with transdiscal pedicle screw placement guided with neuronavigation and compare the results to those achieved previously without image guidance...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29277684/commissural-axon-navigation-in-the-spinal-cord-a-repertoire-of-repulsive-forces-is-in-command
#3
REVIEW
Hugo Ducuing, Thibault Gardette, Aurora Pignata, Servane Tauszig-Delamasure, Valérie Castellani
The navigation of commissural axons in the developing spinal cord has attracted multiple studies over the years. Many important concepts emerged from these studies which have enlighten the general mechanisms of axon guidance. The navigation of commissural axons is regulated by a series of cellular territories which provides the diverse guidance information necessary to ensure the successive steps of their pathfinding towards, across, and away from the ventral midline. In this review, we discuss how repulsive forces, by propelling, channelling, and confining commissural axon navigation, bring key contributions to the formation of this neuronal projection...
December 22, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29276476/critical-points-and-traveling-wave-in-locomotion-experimental-evidence-and-some-theoretical-considerations
#4
REVIEW
Philippe Saltiel, Andrea d'Avella, Matthew C Tresch, Kuno Wyler, Emilio Bizzi
The central pattern generator (CPG) architecture for rhythm generation remains partly elusive. We compare cat and frog locomotion results, where the component unrelated to pattern formation appears as a temporal grid, and traveling wave respectively. Frog spinal cord microstimulation with N-methyl-D-Aspartate (NMDA), a CPG activator, produced a limited set of force directions, sometimes tonic, but more often alternating between directions similar to the tonic forces. The tonic forces were topographically organized, and sites evoking rhythms with different force subsets were located close to the constituent tonic force regions...
2017: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/29274387/common-cues-wire-the-spinal-cord-axon-guidance-molecules-in-spinal-neuron-migration
#5
REVIEW
Zhe Chen
Topographic arrangement of neuronal cell bodies and axonal tracts are crucial for proper wiring of the nervous system. This involves often-coordinated neuronal migration and axon guidance during development. Most neurons migrate from their birthplace to specific topographic coordinates as they adopt the final cell fates and extend axons. The axons follow temporospatial specific guidance cues to reach the appropriate targets. When neuronal or axonal migration or their coordination is disrupted, severe consequences including neurodevelopmental disorders and neurological diseases, can arise...
December 20, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29247503/comparison-of-accuracy-of-pedicle-screw-insertion-among-4-guided-technologies-in-spine-surgery
#6
Yong Fan, Jinpeng Du, Jianan Zhang, Shichang Liu, Xukai Xue, Yunfei Huang, Jing Zhang, Dingjun Hao
BACKGROUND As an available new tool for spinal surgery, robotic technology holds great potential and has been demonstrated to have better clinical outcomes compared with traditional techniques. However, it has not been compared with other assisted tools for the treatment of lumbar degenerative disease. This article focused on studying such variances. MATERIAL AND METHODS A total of 176 pedicle screws were inserted in 39 patients using a spine robot (group 1), 134 screws were implanted in 28 patients using navigational template (group 2), 234 screws were implanted in 51 patients by O-arm-based navigation (group 3), and 346 screws were implanted in 72 patients by fluoroscopy-guided assistance (group 4)...
December 16, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29204980/usefulness-and-radiological-evaluation-of-accuracy-of-innovative-smart-hand-technique-for-pedicle-screw-placement-an-anatomical-study
#7
Ayhan Comert, İhsan Dogan, Y Sukru Çaglar
AIM: The aim of this study is to use a smartphone application during pedicle screw placement navigation and examine the accuracy of this application on anatomical dry vertebrae model. MATERIAL AND METHODS: 76 dry vertebrae were used for this study and pedicle entry points, projections of pedicle screw trajectory lines in lateral and superior aspect of vertebral body were identified and drawn for each vertebra bilaterally. In each position, all angulations were measured directly before the procedure manually...
November 1, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29187744/it-is-a-marathon-rather-than-a-sprint-an-initial-exploration-of-unmet-needs-and-support-preferences-of-caregivers-of-children-with-sci
#8
Susan L Ryerson Espino, Erin H Kelly, Anne Rivelli, Kathy Zebracki, Lawrence C Vogel
STUDY DESIGN: Focus group study. OBJECTIVES: Explore unmet needs and support preferences of caregivers of youth with spinal cord injury (SCI). SETTING: One pediatric specialty rehabilitation hospital system in the United States. METHODS: Four focus groups were conducted with a convenience sample of 26 caregivers who were primarily mothers (96%) and married (65%), and had at least some college education (85%). Children living with SCI were on average 12...
November 30, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29174757/anterior-transcorporeal-tunnel-approach-for-cervical-myelopathy-guided-by-ct-based-intraoperative-spinal-navigation-technical-note
#9
Javier Quillo-Olvera, Guang-Xun Lin, Tsz-King Suen, Hyun-Jin Jo, Jin-Sung Kim
Cervical spondylotic myelopathy (CSM) is the most common degenerative disease of the spine in elderly patients. Although there are several surgical options for the treatment of this disease, minimally invasive techniques for localized decompression of the true clinical generator of the patient's disease has revolutionized spinal surgery recently. This article presents an alternate application of the anterior transcorporeal tunnel approach in combination with computed tomography (CT)-based intraoperative navigation in the treatment of patients with cervical myelopathy secondary to spondylosis...
November 22, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29165642/the-corticospinal-reserve-capacity-reorganization-of-motor-area-and-excitability-as-a-novel-pathophysiological-concept-in-cervical-myelopathy
#10
Anna Zdunczyk, Vera Schwarzer, Michael Mikhailov, Brendon Bagley, Tizian Rosenstock, Thomas Picht, Peter Vajkoczy
BACKGROUND: In degenerative cervical myelopathy (DCM), the dynamics of disease progression and the outcome after surgical decompression vary interindividually and do not necessarily correlate with radiological findings. OBJECTIVE: To improve diagnostic power in DCM by better characterization of the underlying pathophysiology using navigated transcranial magnetic stimulation (nTMS). METHODS: Eighteen patients with DCM due to cervical spinal canal stenosis were examined preoperatively with nTMS...
November 18, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29157032/pain-fatigue-function-and-participation-among-long-term-manual-wheelchair-users-partnered-with-a-mobility-service-dog
#11
Claude Vincent, Dany H Gagnon, Frédéric Dumont
PURPOSE: To assess the effects of a mobility service dog (MSD) on pain, fatigue, wheelchair-related functional tasks, participation and satisfaction among manual wheelchair users over a nine-month period. METHOD: A longitudinal study with repeated assessment times before and three, six and nine months after intervention was achieved. Intervention consisted in partnering each participant with a MSD. The setting is a well-established provincial service dog training school and participants homes...
November 20, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29140961/cervical-foraminal-epidural-blood-patch-for-the-targeted-treatment-of-refractory-cerebrospinal-fluid-leakage-from-a-dural-sleeve
#12
Nuj Tontisirin, Pannawit Benjhawaleemas, Sasikaan Nimmaanrat, Pornchai Sathirapanya, Teeranan Laohawiriyakamol, De Q Tran, Roderick J Finlayson
Epidural blood patches (EBPs) are routinely used to treat symptoms (eg, headaches) associated with spontaneous intracranial hypotension. Although cerebrospinal fluid leakage commonly involves the periforaminal areas of the cervical or thoracic spine, EBPs have been historically performed at the lumbar level. Recent evidence suggests that targeting the causative spinal segment may provide greater clinical benefits. While previous reports have targeted foraminal leaks with segmental thoracic or cervical injections, we present a case report detailing the novel use of a navigable epidural catheter to perform a selective EBP at the C7/T1 foramen...
November 14, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29130140/transforaminal-intrathecal-delivery-of-nusinersen-using-cone-beam-computed-tomography-for-children-with-spinal-muscular-atrophy-and-extensive-surgical-instrumentation-early-results-of-technical-success-and-safety
#13
John J Weaver, Niranjana Natarajan, Dennis W W Shaw, Susan D Apkon, Kevin S H Koo, Giri M Shivaram, Eric J Monroe
BACKGROUND: Nusinersen, the only treatment approved by the United States Food and Drug Administration for spinal muscular atrophy (SMA), is delivered intrathecally. Many children with SMA have extensive spinal instrumentation and deformities, often precluding the use of standard approaches for gaining intrathecal access. Furthermore the anatomical distortion that often occurs with rotoscoliosis can complicate the use of fluoroscopic guidance. Compared to fluoroscopy, CT affords superior guidance for complex needle placements...
November 13, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29107727/severe-spinal-cord-compression-by-a-pure-giant-intradural-schwannoma-of-the-cervical-spine
#14
Javier Quillo-Olvera, Guang-Xun Lin, Jin-Sung Kim
A 73-year-old man with progressive quadriparesis, six months of evolution. Physical examination showed decreased strength at upper and lower limbs together with an increase in osteotendinous reflexes with Babinski sign. Upon radiological investigation, MRI revealed a tumor at C3-T2 with a severe ventrolateral displacement of the spinal cord (Figure 1). The patient underwent surgery for gross total resection of the lesion. Histopathologic findings reported a schwannoma. (Figure 2). Muscular strength of the limbs improved three months after surgery, and the patient was able to walk without assistance...
October 28, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29080030/progenitors-in-the-ependyma-of-the-spinal-cord-a-potential-resource-for-self-repair-after-injury
#15
Nicolás Marichal, Cecilia Reali, María Inés Rehermann, Omar Trujillo-Cenóz, Raúl E Russo
Traumatic injury of the spinal cord leads to devastating conditions that affect ~2.5 million people worldwide. This is because the mammalian spinal cord reacts to injury with only limited endogenous repair. Functional restoration requires the replacement of lost cells, the growth and navigation of regenerating axons on a permissive scaffold and axon re-myelination. The manipulation of endogenous spinal stem cells is regarded as a potential strategy to restore function. For this type of therapy it is necessary to determine the molecular and functional mechanisms regulating the proliferation, migration and differentiation of adult spinal progenitors...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29057348/navigation-accuracy-comparing-non-covered-frame-and-use-of-plastic-sterile-drapes-to-cover-the-reference-frame-in-3d-acquisition
#16
Donald S Corenman, Eric L Strauch, Grant J Dornan, Eric Otterstrom, Lisa Zalepa King
BACKGROUND: Advancements in surgical navigation technology coupled with 3-dimensional (3D) radiographic data have significantly enhanced the accuracy and efficiency of spinal fusion implant placement. Increased usage of such technology has led to rising concerns regarding maintenance of the sterile field, as makeshift drape systems are fraught with breaches thus presenting increased risk of surgical site infections (SSIs). A clinical need exists for a sterile draping solution with these techniques...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29054782/multi-level-spondylolysis-repair-using-the-smiley-face-technique-with-3d-intraoperative-spinal-navigation
#17
Mathew R Voisin, Christopher D Witiw, Ryan Deorajh, Daipayan Guha, Adetunji Oremakinde, Shelly Wang, Victor Yang
BACKGROUND / OBJECTIVE: Multi-level spondylolysis is a rare cause of progressive lower back pain and patients that fail conservative management are treated surgically. Direct repair methods can maintain mobility and lead to decreased morbidity compared with spinal fusion in single-level spondylolysis. In this paper, we present a patient with non-adjacent multi-level spondylolysis that underwent the 'smiley face' technique of direct multi-level repair without fusion using 3D intraoperative spinal navigation...
October 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29050896/intraoperative-pedicle-screw-navigation-does-not-significantly-affect-complication-rates-after-spine-surgery
#18
Scott C Wagner, Patrick B Morrissey, Ian D Kaye, Arjun Sebastian, Joseph S Butler, Christopher K Kepler
Various forms of intraoperative computer-assisted navigation technologies exist, and have consistently been shown to improve pedicle screw accuracy. However, the overall clinical effects of inaccurate pedicle screw placement have been debated. We examined the clinical effects of improved pedicle screw accuracy with computer navigation technology in reducing complication rates in patients undergoing multi-level spinal fusion. We retrospectively reviewed the ACS-NSQIP registry utilizing Current Procedural Terminology (CPT) codes 22843 + 22844 to identify patients undergoing spinal instrumentation of greater than 7 levels, as well as the CPT code 61783 to denote the use of intraoperative computer-assisted navigation...
October 16, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29019807/pedicle-screw-insertion-accuracy-using-o-arm-robotic-guidance-or-freehand-technique-a-comparative-study
#19
Pietro Aniello Laudato, Katarzyna Pierzchala, Constantin Schizas
STUDY DESIGN: Retrospective radiological study OBJECTIVE.: To evaluate the accuracy of pedicle screw insertion using O-Arm navigation, Robotic assistance or a freehand fluoroscopic technique. SUMMARY OF BACKGROUND DATA: Pedicle screw insertion using either 'O-Arm' navigation or robotic devices is gaining popularity. Although several studies are available evaluating each of those techniques separately, no direct comparison has been attempted. METHODS: 84 patients undergoing implantation of 569 lumbar and thoracic screws were divided in three groups...
October 10, 2017: Spine
https://www.readbyqxmd.com/read/29018961/accuracy-of-a-patient-specific-template-for-pedicle-screw-placement-compared-with-a-conventional-method-a-meta-analysis
#20
Yong Fan, Jin-Peng Du, Qi-Ning Wu, Jia-Nan Zhang, Ding-Jun Hao
INTRODUCTION: Accurate placement of pedicle screws in spine surgery is a challenge for surgeons. Patient-specific template techniques have the potential for improving the accuracy of screw placement. The target of this analysis was to investigate differences in terms of accuracy of pedicle screw insertion between patient-specific template assistance and the conventional free-hand method for reconstruction of spinal stability. MATERIALS: The Cochrane Library, Ovid, Web of Science, PubMed, EMBASE and CNKI database were searched until February 2017 for a systematic review, and several comparative studies were screened for comparisons of accuracies of pedicle screw insertion with patient-specific assistance and conventional methods...
October 10, 2017: Archives of Orthopaedic and Trauma Surgery
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