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https://www.readbyqxmd.com/read/28726731/the-use-of-imaging-in-the-prediction-and-assessment-of-cancer-treatment-toxicity
#1
REVIEW
Hossein Jadvar
Multimodal imaging is commonly used in the management of patients with cancer. Imaging plays pivotal roles in the diagnosis, initial staging, treatment response assessment, restaging after treatment and the prognosis of many cancers. Indeed, it is difficult to imagine modern precision cancer care without the use of multimodal molecular imaging, which is advancing at a rapid pace with innovative developments in imaging sciences and an improved understanding of the complex biology of cancer. Cancer therapy often leads to undesirable toxicity, which can range from an asymptomatic subclinical state to severe end organ damage and even death...
July 20, 2017: Diagnostics
https://www.readbyqxmd.com/read/28724947/marker-trait-association-analysis-of-frost-tolerance-of-672-worldwide-pea-pisum-sativum-l-collections
#2
Rong Liu, Li Fang, Tao Yang, Xiaoyan Zhang, Jinguo Hu, Hongyan Zhang, Wenliang Han, Zeke Hua, Junjie Hao, Xuxiao Zong
Frost stress is one of the major abiotic stresses causing seedling death and yield reduction in winter pea. To improve the frost tolerance of pea, field evaluation of frost tolerance was conducted on 672 diverse pea accessions at three locations in Northern China in three growing seasons from 2013 to 2016 and marker-trait association analysis of frost tolerance were performed with 267 informative SSR markers in this study. Sixteen accessions were identified as the most winter-hardy for their ability to survive in all nine field experiments with a mean survival rate of 0...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28721836/assisted-reproductive-technologies-a-hierarchy-of-risks-for-conception-pregnancy-outcomes-and-treatment-decisions
#3
M J Davies, A R Rumbold, V M Moore
The use of assisted reproductive technologies (ART) for the treatment of infertility has grown exponentially over the last 20 years, and now accounts for 4% of all births in Australia, and over 1 m births annually around the globe. There is consistent reporting of increased risk of adverse perinatal outcomes and birth defects following infertility treatment. However, change in practice has been stymied by critical knowledge gaps with regards to (a) the relative contribution of patient and treatment factors to adverse outcomes, (b) the independent contribution of specific contemporary treatments and treatment combinations to outcomes, (c) the impact of innovations in laboratory and clinical practice on treatment success and observed risk and (d) changes over time in patient characteristics...
August 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28721691/occupational-therapy-for-adults-with-problems-in-activities-of-daily-living-after-stroke
#4
REVIEW
Lynn A Legg, Sharon R Lewis, Oliver J Schofield-Robinson, Avril Drummond, Peter Langhorne
BACKGROUND: A stroke occurs when the blood supply to part of the brain is cut off. Activities of daily living (ADL) are daily home-based activities that people carry out to maintain health and well-being. ADLs include the ability to: eat and drink unassisted, move, go to the toilet, carry out personal hygiene tasks, dress unassisted, and groom. Stroke causes impairment-related functional limitations that may result in difficulties participating in ADLs independent of supervision, direction, or physical assistance...
July 19, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28720693/catastrophic-cervical-spinal-injury-in-an-amateur-college-wrestler
#5
Jayakrishnan Kelamangalathu Narayana Kurup, Ravitheja Jampani, Simanchal P Mohanty
A young amateur wrestler presented with a burst fracture of the seventh cervical vertebra with complete paraplegia. He was treated with surgery for spine stabilisation and was actively rehabilitated. Adolescents and teenagers are indulging in high-contact sports like wrestling, without proper training and technical know-how, which can lead to severe injuries and possibly, permanent handicap or death. Trainers, assistants and institutions should be well equipped to diagnose and provide initial care of people with a spinal injury to prevent a partial injury from progressing to complete injury...
July 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28718797/socioeconomic-differences-in-and-predictors-of-home-based-palliative-care-health-service-use-in-ontario-canada
#6
Jiaoli Cai, Denise N Guerriere, Hongzhong Zhao, Peter C Coyte
The use of health services may vary across people with different socioeconomic statuses, and may be determined by many factors. The purposes of this study were (i) to examine the socioeconomic differences in the propensity and intensity of use for three main home-based health services, that is, home-based palliative care physician visits, nurse visits and personal support worker (PSW) hours; and (ii) to explore the determinants of the use of home-based palliative care services. A prospective cohort study was employed...
July 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28716621/healthcare-professionals-attitudes-about-physician-assisted-death-an-analysis-of-their-justifications-and-the-roles-of-terminology-and-patient-competency
#7
Derek W Braverman, Brian S Marcus, Paul G Wakim, Mark R Mercurio, Gary S Kopf
CONTEXT: Healthcare professionals (HCPs) are crucial to physician-assisted death (PAD) provision. OBJECTIVES: To quantitatively assess the favorability of justifications for or against PAD legalization among HCPs, the effect of the terms "suicide" and "euthanasia" on their views, and their support for three forms of PAD. METHODS: Our questionnaire presented three cases: physician-assisted suicide, euthanasia for a competent patient, and euthanasia for an incompetent patient with an advance directive for euthanasia...
July 14, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28716124/implementing-maternal-death-surveillance-and-response-a-review-of-lessons-from-country-case-studies
#8
Helen Smith, Charles Ameh, Natalie Roos, Matthews Mathai, Nynke van den Broek
BACKGROUND: Maternal Death Surveillance and Response (MDSR) implementation is monitored globally, but not much is known about what works well, where and why in scaling up. We reviewed a series of country case studies in order to determine whether and to what extent these countries have implemented the four essential components of MDSR and identify lessons for improving implementation. METHODS: A secondary analysis of ten case studies from countries at different stages of MDSR implementation, using a policy analysis framework to draw out lessons learnt and opportunities for improvement...
July 17, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28712955/clinical-impact-of-changes-in-hemodynamic-indices-of-contractile-function-during-treatment-of-acute-decompensated-heart-failure
#9
Kenneth C Bilchick, Eliany Mejia-Lopez, Peter McCullough, Khadijah Breathett, Jamie L Kennedy, Jose Tallaj, James Bergin, Salpy Pamboukian, Mohammad Abuannadi, Sula Mazimba
BACKGROUND: The objective was to determine the impact of improving right ventricular versus left ventricular stroke work indices (RVSWI v. LVSWI) during therapy for acute decompensated heart failure (ADHF). METHODS AND RESULTS: Cox proportional hazards regression and logistic regression was used to analyze key factors associated with outcomes in 175 patients (age 56.7 ± 13.6 years, 29.1% female) with hemodynamic data from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial...
July 13, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28712668/treatment-outcomes-of-multidrug-resistant-tuberculosis-patients-in-zhejiang-china-2009-2013
#10
Le Zhang, Qiong Meng, Songhua Chen, Minwu Zhang, Bin Chen, Beibei Wu, Guangsen Yan, Xiaomeng Wang, Zhongwei Jia
OBJECTIVES: To examine treatment outcomes and factors associated with poor outcome of MDR-TB in China. METHODS: Prospective observational cohort study including consecutive patients with MDR-TB between 2009-2013 in six regions of Zhejiang province. Patients were prescribed treatments by infectious disease specialists and treatment outcomes were recorded. Sociodemographic characteristics were obtained through a structured questionnaire. The primary endpoint was poor treatment outcomes, defined as treatment failure based on microbiological persistence, default (lost to follow-up) or death at 24 months...
July 13, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28709816/-current-knowledge-on-perioperative-treatments-of-non-small-cell-lung-carcinomas
#11
REVIEW
S Brosseau, C Naltet, M Nguenang, V Gounant, P Mordant, B Milleron, Y Castier, G Zalcman
Surgery is still the main treatment in early-stage of non-small cell lung cancer with 5-year survival of stage IA patients exceeding 80%, but 5-year survival of stage II patients rapidly decreasing with tumor size, N status, and visceral pleura invasion. The major metastatic risk in such patients has supported clinical research assessing systemic or loco-regional perioperative treatments. Modern phase 3 trials clearly validated adjuvant or neo-adjuvant platinum-based chemotherapy in resected stage I-III patients as a standard treatment of which value has been reassessed several independent meta-analyses, showing a 5% benefit in 5y-survival, and a decrease of the relative risk for death around from 12 to 25%...
July 11, 2017: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/28705229/brugada-syndrome-in-a-patient-with-amyotrophic-lateral-sclerosis-a-case-report
#12
Anusha Battineni, Rohit Gummi, Naresh Mullaguri, Raghav Govindarajan
BACKGROUND: Amyotrophic lateral sclerosis is a fatal neuromuscular disorder characterized by progressive death of the upper and lower motor neurons in the central nervous system. Patients with this disease die mostly as a result of respiratory failure; however, owing to prolonged survival through assisted ventilation, cardiovascular causes are increasingly responsible for mortality. We report what is to the best of our knowledge the first case of type 2 Brugada syndrome causing ventricular tachyarrhythmia and cardiac arrest in a patient with upper limb onset amyotrophic lateral sclerosis...
July 14, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28704089/malaria-diagnosis-treatment-and-management-of-a-critically-ill-patient
#13
Chris Carter, Priscar Sakala Mukonka
Malaria is a significant cause of mortality in many countries and remains the most prevalent parasitic tropical infection. The World Health Organization estimates that 50% of the world's population is at risk of malaria, with most deaths occurring in sub-Saharan Africa. This case study explores the management of a malaria patient admitted to a critical care unit in Zambia, a lower-middle-income country in sub-Saharan Africa. While malaria is prevalent in Zambia and other countries, in the UK all malaria is imported and less frequently seen by health professionals...
July 13, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28702596/characterization-and-cardioprotective-activity-of-anthocyanins-from-nitraria-tangutorum-bobr-by-products
#14
Ming Zhang, Jianbin Ma, Hongtao Bi, Jiayin Song, Hongxia Yang, Zhenghua Xia, Yuzhi Du, Tingting Gao, Lixin Wei
The Nitraria tangutorum Bobr. fruit is an indigenous berry of the shrub belonging to the Zygophyllaceae family which grows at an altitude of over 3000 m in the Tibetan Plateau, and has been used as a native medicinal food for treating weakness of the spleen, stomach syndrome, dyspepsia, neurasthenia, dizziness, etc. for thousands of years. Nowadays, N. tangutorum industrial juice by-products generated from health food production can be a potential low cost source of some unique bioactive ingredients. In a prior study, we established a simultaneous microwave/ultrasonic assisted enzymatic extraction method for extracting antioxidant ingredients from the industrial by-products of N...
July 13, 2017: Food & Function
https://www.readbyqxmd.com/read/28700612/assessing-development-assistance-for-child-survival-between-2000-and-2014-a-multi-sectoral-perspective
#15
Chunling Lu, Annie Chu, Zhihui Li, Jian Shen, Subu Subramanian, Kenneth Hill
BACKGROUND: The majority of Countdown countries did not reach the fourth Millennium Development Goal (MDG 4) on reducing child mortality, despite the fact that donor funding to the health sector has drastically increased. When tracking aid invested in child survival, previous studies have exclusively focused on aid targeting reproductive, maternal, newborn, and child health (RMNCH). We take a multi-sectoral approach and extend the estimation to the four sectors that determine child survival: health (RMNCH and non-RMNCH), education, water and sanitation, and food and humanitarian assistance (Food/HA)...
2017: PloS One
https://www.readbyqxmd.com/read/28698702/six-questions-about-physician-assisted-death-from-a-conscientious-objector
#16
Ewan C Goligher
No abstract text is available yet for this article.
May 2017: Linacre Quarterly
https://www.readbyqxmd.com/read/28697921/new-frameworks-for-understanding-sudden-unexpected-deaths-in-infancy-sudi-in-socially-vulnerable-families
#17
REVIEW
Rebecca Shipstone, Jeanine Young, Lauren Kearney
THEORETICAL PRINCIPLES: Sociological frameworks may enhance understanding of the complex and multidimensional nature of disadvantage, which is prevalent among families who experience Sudden Unexpected Death in Infancy (SUDI). PHENOMENA ADDRESSED: SUDI is the largest category of postneonatal death and largely associated with the social determinants of health. The highly successful 'Back to Sleep' campaign has resulted in a more than 85% decrease in SUDI. However, social inequalities have accompanied this decrease, and the burden of SUDI now lies with the most disadvantaged and socially vulnerable families...
July 8, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28697615/predictors-of-burnout-among-hiv-nurses-in-the-western-cape
#18
Rizwana Roomaney, Jeanette Steenkamp, Ashraf Kagee
BACKGROUND: Burnout has been implicated as one of the reasons for key healthcare personnel, such as nurses, leaving their profession, resulting in insufficient staff to attend to patients. OBJECTIVE: We investigated the predictors of three dimensions of burnout, namely emotional exhaustion, depersonalisation and personal accomplishment, among nurses in South Africa attending to patients living with HIV. METHOD: Participants were recruited at a large tertiary hospital in the Western Cape region, with the help of the assistant director of nursing at the hospital...
June 28, 2017: Curationis
https://www.readbyqxmd.com/read/28696872/anomalous-aortic-origin-of-a-coronary-artery-symptoms-do-not-correlate-with-intramural-length-or-ostial-diameter
#19
Shyamasundar Balasubramanya, Michael C Mongé, Osama M Eltayeb, Anne E Sarwark, John M Costello, Cynthia K Rigsby, Andrada R Popescu, Carl L Backer
BACKGROUND: Anomalous aortic origin of a coronary artery (AAOCA) is a known cause of sudden death. Our hypothesis was that longer intramural length and smaller ostial diameter correlate with preoperative symptoms. If true, this would assist in the decision for surgical indications. We also assessed the accuracy of preoperative imaging to predict intramural length. METHODS: Retrospective analysis of patients who underwent AAOCA unroofing from 2006 to 2014. Patients had preoperative computed tomography angiography (CTA) or magnetic resonance imaging (MRI)...
July 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28693565/two-year-post-discharge-costs-of-care-among-patients-treated-with-transcatheter-or-surgical-aortic-valve-replacement-in-germany
#20
Klaus Kaier, Frederike von Kampen, Hardy Baumbach, Constantin von Zur Mühlen, Philip Hehn, Werner Vach, Manfred Zehender, Christoph Bode, Jochen Reinöhl
BACKGROUND: This study presents data on post-discharge costs of care among patients treated with transcatheter or surgical aortic valve replacement over a two year period. METHODS: Based on a prospective clinical trial, post-discharge utilization of health services and status of assistance were collected for 151 elderly patients via 2250 monthly telephone interviews, valued using standardized unit costs and analysed using two-part regression models. RESULTS: At month 1 post-discharge, total costs of care are substantially elevated (monthly mean: €3506...
July 11, 2017: BMC Health Services Research
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