Steffen Hartleif, James Hodson, Carla Lloyd, Vladimir L Cousin, Piotr Czubkowski, Lorenzo D'Antiga, Dominique Debray, Anthony Demetris, Angelo Di Giorgio, Helen M Evans, Björn Fischler, Emmanuel Gonzales, Annette S H Gouw, Stefan G Hübscher, Emmanuel Jacquemin, Florence Lacaille, Silvia Malenicka, Valerie A McLin, Małgorzata Markiewicz-Kijewska, George V Mazariegos, Jeremy K Rajanayagam, René Scheenstra, Stephan Singer, Françoise Smets, Etienne Sokal, James E Squires, Ekkehard Sturm, Henkjan Verkade, Deirdre A Kelly
BACKGROUND: The histological prevalence of allograft fibrosis in asymptomatic children after liver transplantation (LT) is well documented. However, long-term graft and patient survival remain unclear. This retrospective multicenter study aims to determine the prevalence of allograft fibrosis and analyze the long-term outcome for patients transplanted in childhood. METHODS: We reviewed clinical data of children who had undergone 10-y protocol liver biopsies. We excluded patients with autoimmune hepatitis, primary sclerosing cholangitis, hepatitis B or C, and retransplantation...
May 5, 2023: Transplantation