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Hearing loose

Jan-Christoph Edelmann, Dominik Mair, Thomas Ussmueller
This manuscript introduces a novel concept for measuring coil coupling for extremely loose-coupled coils (coupling factors k<10-6; mutual inductance values M<10-10 H). Such a coupling is found everywhere where the ratio of solenoid diameter to coil spacing is >50. Measuring these quantities with a low-power technology requires a sophisticated setup that goes beyond the sensitivity of state-of-the art approaches. The methodology is validated using laboratory measurements with three sets of solenoids (two ferrite-cored, one air-cored) and numerical simulations with COMSOL Multiphysics 5...
June 12, 2018: Biomedizinische Technik. Biomedical Engineering
Zhiqiang Hou, Xiaohan Wang, Jing Cai, Jinhui Zhang, Ahmed Hassan, Manfred Auer, Xiaorui Shi
Normal blood supply to the cochlea is critical for hearing. Noise damages auditory sensory cells and has a marked effect on the microvasculature in the cochlear lateral wall. Pericytes in the stria vascularis (strial pericytes) are particularly vulnerable and sensitive to acoustic trauma. Exposure of NG2DsRedBAC transgenic mice (6-8 weeks old) to wide-band noise at a level of 120 dB for 3 h per day for 2 consecutive days produced a significant hearing threshold shift and caused pericytes to protrude and migrate from their normal endothelial attachment sites...
June 4, 2018: Journal of the Association for Research in Otolaryngology: JARO
Marcos S Tatagiba, Rocío Evangelista-Zamora, Stefan Lieber
The anterior inferior cerebellar artery (AICA) usually runs loosely within the cerebellopontine cistern; in rare cases, however, it is firmly adherent to the petrous dura mater.1,2 Recognizing this variation is particularly important in vestibular schwannoma surgery via the retrosigmoid transmeatal approach to prevent the high morbidity associated with vascular injury. This video demonstrates a surgical technique to effectively mobilize the AICA when firmly adherent to the petrous dura mater. A 39-year-old man presented with a history of progressive right-sided hearing loss without facial weakness or other associated symptoms3...
March 29, 2018: Operative Neurosurgery (Hagerstown, Md.)
Ingeborg Dhooge, Stéphanie Desmedt, Thomas Maly, David Loose, Helen Van Hoecke
The given and family names of all the co-authors are incorrect in the published article. The correct names should read as follows.
May 2018: European Archives of Oto-rhino-laryngology
Ingeborg Dhooge, Stéphanie Desmedt, Thomas Maly, David Loose, Helen Van Hoecke
OBJECTIVE: To evaluate long-term hearing results of stapedotomy and analyze the influence of patient-, disease-, and procedure-related variables. STUDY DESIGN: Retrospective case series. SETTING: Tertiary referral center. PATIENTS: 230 ears (202 patients, 10-74 years) underwent stapedotomy for otosclerosis between January 2008 and August 2014. All cases had early postoperative follow-up (4 weeks post-surgery) and 181 cases had late postoperative follow-up (≥ 1 year, average 32...
May 2018: European Archives of Oto-rhino-laryngology
Fenghua Xie, Ling You, Dongqin Cai, Miaomiao Liu, Yin Yue, Yiwei Wang, Kexin Yuan
The protracted maturational process of temporal processing in layer 4 (L4) of primary auditory cortex (A1) has been extensively studied. Accumulating evidences show that layer 5 (L5) receives direct thalamic inputs as well. How the temporal responses in L5 may developmentally emerge remains unclear. Using in vivo loose-patch recordings in rat A1, we found that putative pyramidal (Pyr) neurons in developing L5 exhibited adult-like stimulus-following ability but less bursting shortly after hearing onset. L5 Pyr neurons in adult A1 exhibited phase-locking similar to L4 neurons, while L5 fast-spiking (FS) neurons showed greater phase-locking at 7 and 12...
October 31, 2017: Cerebral Cortex
Philomena Ostapchuk, Maarit Suomalainen, Yueting Zheng, Karin Boucke, Urs F Greber, Patrick Hearing
The Adenovirus (Ad) genome within the capsid is tightly associated with a virus-encoded, histone-like core protein-protein VII. Two other Ad core proteins, V and X/μ, also are located within the virion and are loosely associated with viral DNA. Core protein VII remains associated with the Ad genome during the early phase of infection. It is not known if naked Ad DNA is packaged into the capsid, as with dsDNA bacteriophage and herpesviruses, followed by the encapsidation of viral core proteins, or if a unique packaging mechanism exists with Ad where a DNA-protein complex is simultaneously packaged into the virion...
June 2017: PLoS Pathogens
Yi Min Zhang, Xiaoguang Liu
INTRODUCTION: Primary synovial osteochondromatosis of the hip is a benign disorder, which is not frequently seen clinically. The characteristic of this disease is proliferation of synovium and formation of loose bodies inside the joint. It is known that only the loose bodies derived from synovium were called synovial osteochondromatosis. Although it can take place in any joint, the knee is most commonly affected, involvement of the hip joint is relatively rare. We report a young man who has multiple synovial osteochondromatosis in his left hip...
November 2016: Journal of Orthopaedic Case Reports
Dongqin Cai, Rongrong Han, Miaomiao Liu, Fenghua Xie, Ling You, Yi Zheng, Limin Zhao, Jun Yao, Yiwei Wang, Yin Yue, Christoph E Schreiner, Kexin Yuan
Faithful representation of sound envelopes in primary auditory cortex (A1) is vital for temporal processing and perception of natural sounds. However, the emergence of cortical temporal processing mechanisms during development remains poorly understood. Although cortical inhibition has been proposed to play an important role in this process, direct in-vivo evidence has been lacking. Using loose-patch recordings in rat A1 immediately after hearing onset, we found that stimulus-following ability in fast-spiking neurons was significantly better than in regular-spiking (RS) neurons...
May 1, 2018: Cerebral Cortex
Costanza Papagno, Giovanna Minniti, Giulia C Mattavelli, Lara Mantovan, Carlo Cecchetto
To verify whether loosing a sense or two has consequences on a spared sensory modality, namely touch, and whether these consequences depend on practice or are biologically determined, we investigated 13 deafblind participants, 16 deaf participants, 15 blind participants, and 13 matched normally sighted and hearing controls on a tactile short-term memory task, using checkerboard matrices of increasing length in which half of the squares were made up of a rough texture and half of a smooth one. Time of execution of a fixed matrix, number of correctly reproduced matrices, largest matrix correctly reproduced and tactile span were recorded...
February 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Jingjing Sherry Wu, Eric D Young, Elisabeth Glowatzki
Auditory nerve fibers (ANFs) exhibit a range of spontaneous firing rates (SRs) that are inversely correlated with threshold for sounds. To probe the underlying mechanisms and time course of SR differentiation during cochlear maturation, loose-patch extracellular recordings were made from ANF dendrites using acutely excised rat cochlear preparations of different ages after hearing onset. Diversification of SRs occurred mostly between the second and the third postnatal week. Statistical properties of ANF spike trains showed developmental changes that approach adult-like features in older preparations...
October 12, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Jared J Tompkins, Dana K Petersen, Daniel D Sharbel, Brian J McKinnon, C Bruce MacDonald
Implantation of auditory osseointegrated implants, also known as bone-anchored hearing systems (BAHS), represents a surgical option for select pediatric patients aged 5 years or older with hearing loss. Functional indications in this patient population include conductive or mixed hearing loss. Common complications of implantation include skin infections, chronic skin irritation, hypertrophic skin overgrowth, and loose abutments. In a case series of 15 pediatric patients, we discovered an unexpectedly high skin-related complication rate requiring surgical revision of 53%...
July 2016: International Journal of Pediatric Otorhinolaryngology
Qi Dai, Zhicun Zhang, Quan Liu, Hongmeng Yu
CONCLUSIONS: Transplantation of OECs into the cochlea may protect and increase the survival of SGCs. OBJECTIVE: To investigate the protective effect of the transplantation of olfactory ensheathing cells (OECs) on injured spiral ganglion cells (SGCs) in rats. METHODS: OECs were transplanted into the cochlea in rats with SGCs that were injured by kanamycin sulfate (KM). An equal volume of D-Hanks was injected into the cochlea of control rats...
November 2016: Acta Oto-laryngologica
Haishi Zhang, Jian Xu, Danqi Chen, Xiang Huang, Ping Zhong
Here we reported the first case of left cerebellopontine angle acoustic neurinoma with calcification in our department. The patient was 65 year-old, suffering from progressive loss of hearing in the left ear for about 30 years and headache with unsteady gait for approximately 6 months. Head CT & MRI scan identified an intracranial lesion located on left cerebellopontine angle. Left suboccipital retrosigmoid approach was applied to perform the operation after patient consent. The tumor was completely resected without complication and the patient recovered well...
2015: International Journal of Clinical and Experimental Medicine
Trevor J Wardill, Katie Knowles, Laura Barlow, Gervasio Tapia, Karin Nordström, Robert M Olberg, Paloma T Gonzalez-Bellido
Predatory animals have evolved to optimally detect their prey using exquisite sensory systems such as vision, olfaction and hearing. It may not be so surprising that vertebrates, with large central nervous systems, excel at predatory behaviors. More striking is the fact that many tiny insects, with their miniscule brains and scaled down nerve cords, are also ferocious, highly successful predators. For predation, it is important to determine whether a prey is suitable before initiating pursuit. This is paramount since pursuing a prey that is too large to capture, subdue or dispatch will generate a substantial metabolic cost (in the form of muscle output) without any chance of metabolic gain (in the form of food)...
September 2015: Brain, Behavior and Evolution
Alicia M Quesnel, Hideko Heidi Nakajima, John J Rosowski, Marlan R Hansen, Bruce J Gantz, Joseph B Nadol
After initially successful preservation of residual hearing with cochlear implantation, some patients experience subsequent delayed hearing loss. The etiology of such delayed hearing loss is unknown. Human temporal bone pathology is critically important in investigating the etiology, and directing future efforts to maximize long term hearing preservation in cochlear implant patients. Here we present the temporal bone pathology from a patient implanted during life with an Iowa/Nucleus Hybrid S8 implant, with initially preserved residual hearing and subsequent hearing loss...
March 2016: Hearing Research
Douglas E Vetter
Hearing loss afflicts approximately 15% of the world's population, and crosses all socioeconomic boundaries. While great strides have been made in understanding the genetic components of syndromic and non-syndromic hearing loss, understanding of the mechanisms underlying noise-induced hearing loss (NIHL) have come much more slowly. NIHL is not simply a mechanism by which older individuals loose their hearing. Significantly, the incidence of NIHL is increasing, and is now involving ever younger populations. This may predict future increased occurrences of hearing loss...
September 1, 2015: Biochemical Pharmacology
H G Mueller
Probe-microphone testing was conducted in the laboratory as early as the 1940s (e.g., the classic work of Wiener and Ross, reported in 1946), however, it was not until the late 1970s that a "dispenser friendly" system was available for testing hearing aids in the real ear. In this case, the term "dispenser friendly," is used somewhat loosely. The 1970s equipment that I'm referring to was first described in a paper that was presented by Earl Harford, Ph.D. in September of 1979 at the International Ear Clinics' Symposium in Minneapolis...
June 2001: Trends in Amplification
Eunkyung Kim, Hyejin Kang, Hyekyoung Lee, Hyo-Jeong Lee, Myung-Whan Suh, Jae-Jin Song, Seung-Ha Oh, Dong Soo Lee
Prolonged deprivation of auditory input can change brain networks in pre- and postlingual deaf adults by brain-wide reorganization. To investigate morphological changes in these brains voxel-based morphometry, voxel-wise correlation with the primary auditory cortex, and whole brain network analyses using morphological covariance were performed in eight prelingual deaf, eleven postlingual deaf, and eleven hearing adults. Network characteristics based on graph theory and network filtration based on persistent homology were examined...
September 2014: Hearing Research
Hirohito M Kondo, Iwaki Toshima, Daniel Pressnitzer, Makio Kashino
The perceptual organization of auditory scenes is a hard but important problem to solve for human listeners. It is thus likely that cues from several modalities are pooled for auditory scene analysis, including sensory-motor cues related to the active exploration of the scene. We previously reported a strong effect of head motion on auditory streaming. Streaming refers to an experimental paradigm where listeners hear sequences of pure tones, and rate their perception of one or more subjective sources called streams...
2014: Frontiers in Neuroscience
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