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https://www.readbyqxmd.com/read/27896884/contact-allergy-to-preservatives-essca-results-with-the-baseline-series-2009-2012
#1
Ana M Giménez-Arnau, Gustavo Deza, Andrea Bauer, Graham A Johnston, Vera Mahler, Marie-Louise Schuttelaar, Javier Sanchez-Perez, Juan Francisco Silvestre, Mark Wilkinson, Wolfgang Uter
BACKGROUND: Allergic contact dermatitis caused by biocides is common, and causes significant patient morbidity. OBJECTIVE: To describe the current frequency and pattern of patch test reactivity to biocide allergens included in the baselines series of most European countries. METHODS: Data collected by the European Surveillance System on Contact Allergies (ESSCA) network between 2009 and 2012 from 12 European countries were analysed. RESULTS: Methylisothiazolinone 0...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27803959/accelerated-partial-breast-irradiation-with-external-beam-radiotherapy-first-results-of-the-german-phase%C3%A2-2-trial
#2
Oliver J Ott, Vratislav Strnad, Wilhelm Stillkrieg, Wolfgang Uter, Matthias W Beckmann, Rainer Fietkau
BACKGROUND AND PURPOSE: To evaluate the feasibility and efficacy of external beam three-dimensional (3D) conformal accelerated partial breast irradiation (APBI) for selected patients with early breast cancer. PATIENTS AND METHODS: Between 2011 and 2016, 72 patients were recruited for this prospective phase 2 trial. Patients were eligible for APBI if they had histologically confirmed breast cancer or pure ductal carcinoma in situ (DCIS), a tumor diameter ≤3 cm, clear resection margins ≥2 mm, no axillary lymph node involvement, no distant metastases, tumor bed clips, and were aged ≥50 years...
November 1, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27780882/sickness-absence-among-peer-supported-drivers-after-occupational-trauma
#3
A Clarner, W Uter, L Ruhmann, N Wrenger, A Martin, H Drexler
BACKGROUND: Psychological first aid is a common approach for providing support after potentially traumatic events (PTEs). In Germany, a peer support model is recommended by the German Statutory Accident Insurance (DGUV) to reduce sickness absence after occupational accidents, especially in public transportation. However, data on the effectiveness of peer support are very sparse. AIMS: To analyse whether peer support has an impact on sickness absence after work-related traumatic events in public transportation...
October 25, 2016: Occupational Medicine
https://www.readbyqxmd.com/read/27754448/protection-from-ultraviolet-radiation-during-childhood-the-parental-perspective-in-bavaria
#4
Olaf Gefeller, Wolfgang Uter, Annette B Pfahlberg
During childhood, parents play a vital role in sun protection of their children. Their guidance is essential for avoiding excessive exposure to ultraviolet (UV) radiation, a risk factor for developing skin cancer in later life. In a population-based cross-sectional study conducted between October 2011 and February 2012, we assessed how 3281 parents implemented sun protection for their three- to six-year-old children in practice. In particular, clothing, shade-seeking behavior, wearing of sunhats and sunglasses, use of sunscreens and the amount of time spent outdoors were ascertained in two settings (beach, garden/playground)...
October 14, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27649803/association-between-month-of-birth-and-melanoma-risk-fact-or-fiction
#5
Cornelia Fiessler, Annette B Pfahlberg, Andrea K Keller, Martin Radespiel-Tröger, Wolfgang Uter, Olaf Gefeller
BACKGROUND: Evidence on the effect of ultraviolet radiation (UVR) exposure in infancy on melanoma risk in later life is scarce. Three recent studies suggest that people born in spring carry a higher melanoma risk. Our study aimed at verifying whether such a seasonal pattern of melanoma risk actually exists. METHODS: Data from the population-based Cancer Registry Bavaria (CRB) on the birth months of 28 374 incident melanoma cases between 2002 and 2012 were analysed and compared with data from the Bavarian State Office for Statistics and Data Processing on the birth month distribution in the Bavarian population...
September 20, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27633650/comparative-sensitizing-potencies-of-fragrances-preservatives-and-hair-dyes
#6
Carola Lidén, Kerem Yazar, Jeanne D Johansen, Ann-Therese Karlberg, Wolfgang Uter, Ian R White
The local lymph node assay (LLNA) is used for assessing sensitizing potential in hazard identification and risk assessment for regulatory purposes. Sensitizing potency on the basis of the LLNA is categorized into extreme (EC3 value of ≤0.2%), strong (>0.2% to ≤2%), and moderate (>2%). To compare the sensitizing potencies of fragrance substances, preservatives, and hair dye substances, which are skin sensitizers that frequently come into contact with the skin of consumers and workers, LLNA results and EC3 values for 72 fragrance substances, 25 preservatives and 107 hair dye substances were obtained from two published compilations of LLNA data and opinions by the Scientific Committee on Consumer Safety and its predecessors...
November 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27622254/effectiveness-of-an-employee-skin-cancer-screening-program-for-secondary-prevention
#7
Ugur Uslu, Felix Hees, Eva Winnik, Wolfgang Uter, Michael Sticherling
Incidences of UV-induced skin cancer are continuously increasing. For this reason, early diagnosis is becoming more important. In this study, 783 employees of a technical company participated in an employee skin cancer screening program, which consisted of a physical examination for benign and malignant skin lesions and premalignant conditions. To ensure the quality of the examinations, screening was only performed by 5 trained dermatologists. Participants also were asked to complete a standardized questionnaire prior to examination...
August 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/27577494/the-effect-of-exposure-to-ultraviolet-radiation-in-infancy-on-melanoma-risk
#8
Olaf Gefeller, Cornelia Fiessler, Martin Radespiel-Tröger, Wolfgang Uter, Annette B Pfahlberg
Evidence on the effect of ultraviolet radiation (UVR) exposure in infancy on melanoma risk in later life is scarce. Three recent studies suffering from methodological shortcomings suggested that people born in spring carry a higher melanoma risk. Data from the Bavarian population-based cancer registry on 28374 incident melanoma cases between 2002 and 2012 were analyzed to reexamine this finding. Crude and adjusted analyses - using negative binomial regression models - were performed addressing the relationship...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27464585/contact-allergy-to-ingredients-of-topical-medications-results-of-the-european-surveillance-system-on-contact-allergies-essca-2009-2012
#9
Wolfgang Uter, Radoslaw Spiewak, Susan M Cooper, Mark Wilkinson, Javier Sánchez Pérez, Axel Schnuch, Marie-Louise Schuttelaar
PURPOSE: The aim of this study was to give an overview of the prevalence of contact allergy to active ingredients and excipients of topical medications across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies (www.essca-dc.org) with substances applied to consecutively patch tested patients, 2009-2012, in 54 departments in 12 European countries. RESULTS: In view of the varying composition of the baseline series used in the previously mentioned departments and countries, between 58 833 (lanolin alcohols) and 16 498 patients (sodium metabisulfite) were patch tested with the topical agents covered in this study...
July 28, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27422584/gec-estro-multicenter-phase-3-trial-accelerated-partial-breast-irradiation-with-interstitial-multicatheter-brachytherapy-versus-external-beam-whole-breast-irradiation-early-toxicity-and-patient-compliance
#10
Oliver J Ott, Vratislav Strnad, Guido Hildebrandt, Daniela Kauer-Dorner, Hellen Knauerhase, Tibor Major, Jaroslaw Łyczek, José Luis Guinot, Jürgen Dunst, Cristina Gutierrez Miguelez, Pavel Slampa, Michael Allgäuer, Kristina Lössl, Bülent Polat, György Kovács, Arnt-René Fischedick, Thomas G Wendt, Rainer Fietkau, Rolf-Dieter Kortmann, Alexandra Resch, Anna Kulik, Leo Arribas, Peter Niehoff, Ferran Guedea, Annika Schlamann, Richard Pötter, Christine Gall, Martina Malzer, Wolfgang Uter, Csaba Polgár
BACKGROUND AND PURPOSE: To compare early side effects and patient compliance of accelerated partial breast irradiation (APBI) with multicatheter brachytherapy to external beam whole breast irradiation (WBI) in a low-risk group of patients with breast cancer. MATERIAL AND METHODS: Between April 2004 and July 2009, 1328 patients with UICC stage 0-IIA breast cancer were randomized to receive WBI with 50Gy and a boost of 10Gy or APBI with either 32.0Gy/8 fractions, or 30...
July 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27402420/patch-test-results-with-rubber-series-in-the-european-surveillance-system-on-contact-allergies-essca-2013-14
#11
Wolfgang Uter, Katharine Warburton, Elke Weisshaar, Dagmar Simon, Barbara Ballmer-Weber, Vera Mahler, Thomas Fuchs, Johannes Geier, Mark Wilkinson
BACKGROUND: Contact allergy to rubber additives is common, particularly in patients with occupational dermatitis. OBJECTIVES: To descriptively analyse and compare patch test reactions in patients patch tested both with the baseline series and with an additional 'rubber series' as used in the department. METHODS: Patch test data from those members of the European Surveillance System on Contact Allergies (ESSCA) network (www.essca-dc.org) who also contributed data on rubber series patch test results were retrospectively analysed...
December 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27385522/essca-results-with-nickel-cobalt-and-chromium-2009-2012
#12
Wolfgang Uter, Francesca Larese Filon, Francesca Rui, Anna Balato, Mark Wilkinson, Beata Kręcisz, Dorota Chomiczewska-Skora, Marta Kieć-Świerczyńska, Marie-Louise A Schuttelaar, Peter J Frosch, Andreas J Bircher
No abstract text is available yet for this article.
August 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27373245/survey-of-sensitizing-components-of-oxidative-hair-dyes-retail-and-professional-products-in-germany
#13
Stephan Kirchlechner, Anja Hübner, Wolfgang Uter
BACKGROUND: Components of oxidative hair dyes, such as p-toluylenediamine, are very potent contact sensitizers to which many consumers as well as hairdressers and their clients are commonly exposed. METHODS: Based on the qualitative composition of both retail and professional haircare products as determined by package labeling (according to INCI), we conducted a survey on the exposure to active components of oxidative hair dyes in Germany. The joint occurrence of components is also discussed...
July 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27373244/survey-zu-sensibilisierenden-inhaltsstoffen-von-oxidativen-haarfarben-konsumenten-und-kabinettware-in-deutschland
#14
Stephan Kirchlechner, Anja Hübner, Wolfgang Uter
HINTERGRUND: Bestandteile oxidativer Haarfarben, wie z. B. p-Toluylendiamin, sind zum einen teils hochpotente Kontaktallergene, zum anderen sind zahlreiche Verbraucher, Friseurkunden bzw. Friseure exponiert. METHODIK: Survey zur Exposition gegenüber aktiven Komponenten oxidativer Haarfarben in Deutschland, basierend auf der Erfassung der qualitativen Produktrezeptur nach INCI, gesondert für Konsumenten- und die in den Salons verwendete "Kabinett"-Ware, bei der auch das gemeinsame Vorkommen der Bestandteile dargestellt wird...
July 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27211108/long-term-development-of-parental-knowledge-about-skin-cancer-risks-in-germany-has-it-changed-for-the-better
#15
Olaf Gefeller, Wolfgang Uter, Annette B Pfahlberg
Substantial public health efforts have been undertaken throughout the last 25years to increase awareness about skin cancer risks in the German population. An evaluation of long-term effects of these awareness campaigns and preventive activities on the population level and in specific subgroups is yet lacking. We address the temporal development of knowledge about skin cancer risk factors and agreement to the necessity of sun protection in different outdoor situations among parents of young children. We compiled data from four population-based surveys comprising data from 8184 parents of 3- to 6-year-old children in two regions of Germany performed over a nineteen-year period between 1993 and 2012...
August 2016: Preventive Medicine
https://www.readbyqxmd.com/read/27199097/essca-results-with-the-baseline-series-2002-2012-p-phenylenediamine
#16
Marie-Louise A Schuttelaar, Tatiana A Vogel, Francesca Rui, Beata Kręcisz, Dorota Chomiczewska-Skora, Marta Kieć-Świerczyńska, Wolfgang Uter, Francesca Larese Filon
BACKGROUND: Allergic contact dermatitis caused by p-phenylenediamine (PPD) is common among all age groups and both sexes. Monitoring of prevalence and intensity of sensitization is important. OBJECTIVE: To evaluate contact allergy to PPD in Europe, and to compare reaction intensities in different European regions. METHODS: Data collected by the European Surveillance System on Contact Allergies (ESSCA) network between 2002 and 2012 from 12 European countries were analysed regarding prevalence, grading of positive reactions to PPD, and relevance...
September 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27040883/does-a-short-patch-test-training-course-have-an-impact
#17
Wolfgang Uter, Olaf Gefeller, Vera Mahler
No abstract text is available yet for this article.
May 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/26905626/registries-in-clinical-epidemiology-the-european-surveillance-system-on-contact-allergies-essca
#18
W Uter, A Schnuch, M Wilkinson, A Dugonik, B Dugonik, T Ganslandt
BACKGROUND: Disease registries rely on consistent electronic data capturing (EDC) pertinent to their objectives; either by using existing electronic data as far as available, or by implementing specific software solutions. OBJECTIVES: To describe the current practice of an international disease registry (European Surveillance System on Contact Allergies, ESSCA, www.essca-dc.org) against different state of the art approaches for EDC. METHODS: Since 2002, ESSCA is collecting data, currently from 53 departments in 12 countries...
2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/26841273/high-grade-histology-as-predictor-of-early-distant-metastases-and-decreased-disease-free-survival-in-salivary-gland-cancer-irrespective-of-tumor-subtype
#19
Marlen Haderlein, Claudia Scherl, Sabine Semrau, Sebastian Lettmaier, Wolfgang Uter, Friedrich Wilhelm Neukam, Heinrich Iro, Abbas Agaimy, Rainer Fietkau
BACKGROUND: The purpose of this study was to evaluate risk factors that influence overall survival (OS)/disease-free survival (DFS)/locoregional recurrence-free survival (LRFS), and distant metastases-free survival (DMFS) in patients with high-risk primary salivary gland carcinoma who underwent surgery and postoperative (chemo)radiotherapy with curative intention. METHODS: We reviewed data of 63 patients with high-risk primary salivary gland carcinoma in a retrospective single-center audit...
April 2016: Head & Neck
https://www.readbyqxmd.com/read/26708538/fragrance-contact-allergy-in-the-population
#20
COMMENT
W Uter
No abstract text is available yet for this article.
December 2015: British Journal of Dermatology
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