keyword
MENU ▼
Read by QxMD icon Read
search

phase transition

keyword
https://www.readbyqxmd.com/read/28537766/pirfenidone-induces-g1-arrest-in-human-tenon-s-fibroblasts-in-vitro-involving-akt-and-mapk-signaling-pathways
#1
Xiujuan Guo, Yangfan Yang, Liling Liu, Xiaoan Liu, Jiangang Xu, Kaili Wu, Minbin Yu
PURPOSE: To investigate the underlying mechanism by which pirfenidone blocks the transition from the G1 to S phase in primary human Tenon's fibroblasts. METHODS: Primary human Tenon's fibroblasts were characterized by immunocytofluorescence staining with vimentin, fibroblast surface protein, and cytokeratin. After treating Tenon's fibroblasts with pirfenidone under proliferation conditions (10% fetal bovine serum), cell proliferation was measured using a WST-1 assay...
May 24, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28537749/water-microsolvation-can-switch-the-binding-mode-of-ni-ii-with-small-peptides
#2
Robert C Dunbar, Jonathan Martens, Giel Berden, Jos Oomens
Ni(II) ions can be caged by surrounding peptide ligands in two basic binding patterns: the "iminol" (IM) binding pattern, where chelation occurs by deprotonated amide nitrogens, or the charge-solvated (CS) binding pattern, where chelation occurs by amide carbonyl oxygens. Gas-phase observation may clarify the factors affecting this choice in solution and in peptide and protein matrices. Infrared-spectroscopic determination of gas-phase structures shows here how microsolvation by just one water molecule switches the balance of this choice from IM to CS for the Ni2+Gly3 complex, in contrast to the always-CS structure of the Ni2+Gly4 complex...
May 24, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28537747/examination-of-the-mechanism-of-the-yield-of-n2o-from-nitroxyl-hno-in-the-solution-phase-by-theoretical-calculations
#3
Kaiqiang Zhang, Stefan T Thynell
The dimerization of HNO and subsequent yield of N2O in aqueous solution are studied based on the theoretical calculations and kinetic simulations. The initial dimerization reactions were computed at various levels of theory and large divergence was observed in the predictions of the gas-phase free energies. The T1 diagnostics at CCSD(T)/aug-cc-pVTZ suggests multireference characteristics of the HNO dimers and the transition states. The solution-phase free energies were obtained using the wB97XD method and the SMD solvation model...
May 24, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28537739/modeling-the-effect-of-polymer-chain-stiffness-on-the-behavior-of-polymer-nanocomposites
#4
José Javier Burgos-Mármol, Óscar Álvarez-Machancoses, Alessandro Patti
Due to their central role in industrial formulations spanning from food packaging to smart coatings, polymer nanocomposites have been the object of a remarkable attention over the last two decades. Incorporating nanoparticles (NPs) to a polymer matrix modifies the conformation and mobility of the polymer chains at the NP-polymer interface and can potentially provide materials with enhanced properties as compared to pristine polymers. To this end, it is crucial to predict and control the ability of NPs to diffuse and achieve a good dispersion in the polymer matrix...
May 24, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28535461/raman-spectroscopic-study-of-cyclohexane-at-pressures-below-1000mpa
#5
Erwei Qiao, Haifei Zheng
At present, the room temperature freezing pressure of cyclohexane is still uncertain, and the phase transition pressure of solid I - solid III is not reliable at ambient temperature. In this work, we have performed a Raman spectroscopic study of cyclohexane in a Moissanite anvil cell at pressures below 1000MPa at 25°C, and analyzed the characteristic of Raman brands νs(CH2), νas(CH2) and νb(Ring). Two phase transition pressures 80MPa and 550MPa were determined by a quartz pressure gauge, and they are the room temperature freezing pressure of cyclohexane and the phase transition pressure of solid I to solid III, respectively...
May 16, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28535460/a-synchrotron-infrared-absorption-study-of-pressure-induced-polymerization-of-acrylamide
#6
Himal Bhatt, M N Deo
The hydrogen bonded dimeric structure of the model amide based molecular crystal acrylamide has been investigated under pressure using micro-spectroscopy, employing synchrotron infrared radiation up to 24GPa at room temperature. The high pressure spectra indicate systematic evolution of new features above 4GPa, which have been identified to be due to the emergence of a polymeric phase. The polymerization gets completed up to 16.8GPa and the observed changes are found to be irreversible upon the release of pressure...
May 1, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28535351/inherent-simple-cubic-lattice-being-responsible-for-ultrafast-solid-phase-change-of-ge2sb2te5
#7
Wen-Xiong Song, Zhi-Pan Liu, Limin Liu
Crystallization of solid is generally slow in kinetics for atom trapped in solid. Phase-change materials (PCMs) challenge current theory on its ultrafast reversible amorphous-to-crystal transition. Here by using stochastic surface walking global optimization method, we establish the first global potential energy surface (PES) for Ge2Sb2Te5. By analyzing all structures on global PES, we show that an inherent structural pattern of simple cubic lattice is present universally in low energy structures, either globally in a newly found metastable simple cubic crystal phase or locally in the amorphous structures...
May 23, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28535148/stochastic-gene-expression-conditioned-on-large-deviations
#8
Jordan M Horowitz, Rahul V Kulkarni
The intrinsic stochasticity of gene expression can give rise to large fluctuations and rare events that drive phenotypic variation in a population of genetically identical cells. Characterizing the fluctuations that give rise to such rare events motivates the analysis of large deviations in stochastic models of gene expression. Recent developments in non-equilibrium statistical mechanics have led to a framework for analyzing Markovian processes conditioned on rare events and for representing such processes by conditioning-free driven Markovian processes...
May 23, 2017: Physical Biology
https://www.readbyqxmd.com/read/28535044/mechano-responsive-luminescence-via-crystal-to-crystal-phase-transitions-between-chiral-and-non-chiral-space-groups
#9
Mingoo Jin, Tomohiro Seki, Hajime Ito
Herein, a novel mechano-responsive luminescent (MRL) material based on crystal-to-crystal phase transitions between crystals of a chiral and those of a centrosymmetric space group, accompanied by a change of emission properties, is described. Initially, a gold complex containing a biphenyl moiety, which exhibits an achiral structure in solution, afforded an orange-emitting amorphous phase together with a viscous isotropic oil after evaporation of the solvent. Upon pricking, the orange-emitting oil spontaneously crystallized either in a centrosymmetric or in a chiral space group while simultaneously changing the emission properties...
May 23, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28534908/phase-evolution-of-lithium-intercalation-dynamics-in-2h-mos2
#10
Juan Xia, Jin Wang, Dongliang Chao, Zhen Chen, Zheng Liu, Jer-Lai Kuo, Jiaxu Yan, Ze Xiang Shen
Due to the easy intralayer gliding and weak interlayer van der Waals interaction in transition metal dichalcogenides (TMDs), ion (particularly Li(+)) intercalation has been used to modify and tune their atomic structures to obtain the desired optical, electronic and chemical properties for future optoelectronics and energy storage applications. A good understanding of the transformative structures during intercalation is critical. In this paper, we investigate the structural transformation dynamics of 2H-MoS2 using electrochemical Li(+) intercalation for 2H-MoS2...
May 23, 2017: Nanoscale
https://www.readbyqxmd.com/read/28534898/the-cubic-to-hexagonal-phase-transition-of-cerium-oxide-particles-dynamics-and-structure
#11
Jan Höcker, Jon-Olaf Krisponeit, Thomas Schmidt, Jens Falta, Jan Ingo Flege
Cerium oxide is often applied in today's catalysts due to its remarkable oxygen storage capacity. The changes in stoichiometry during reaction are linked to structural modifications, which in turn affect its catalytic activity. We present a real-time in situ study of the structural transformations of cerium oxide particles on ruthenium(0001) at high temperatures of 700 °C in ultra-high vacuum. Our results demonstrate that the reduction from CeO2 to cubic Ce2O3 proceeds via ordered intermediary phases. The final reduction step from cubic to hexagonal Ce2O3 is accompanied by a lattice expansion, the formation of two new surface terminations, a partial dissolution of the cerium oxide particles, and a massive mass transport of cerium from the particles to the substrate...
May 23, 2017: Nanoscale
https://www.readbyqxmd.com/read/28534501/electronic-evidence-of-temperature-induced-lifshitz-transition-and-topological-nature-in-zrte5
#12
Yan Zhang, Chenlu Wang, Li Yu, Guodong Liu, Aiji Liang, Jianwei Huang, Simin Nie, Xuan Sun, Yuxiao Zhang, Bing Shen, Jing Liu, Hongming Weng, Lingxiao Zhao, Genfu Chen, Xiaowen Jia, Cheng Hu, Ying Ding, Wenjuan Zhao, Qiang Gao, Cong Li, Shaolong He, Lin Zhao, Fengfeng Zhang, Shenjin Zhang, Feng Yang, Zhimin Wang, Qinjun Peng, Xi Dai, Zhong Fang, Zuyan Xu, Chuangtian Chen, X J Zhou
The topological materials have attracted much attention for their unique electronic structure and peculiar physical properties. ZrTe5 has host a long-standing puzzle on its anomalous transport properties manifested by its unusual resistivity peak and the reversal of the charge carrier type. It is also predicted that single-layer ZrTe5 is a two-dimensional topological insulator and there is possibly a topological phase transition in bulk ZrTe5. Here we report high-resolution laser-based angle-resolved photoemission measurements on the electronic structure and its detailed temperature evolution of ZrTe5...
May 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28533808/how-one-institution-overcame-the-challenges-to-start-an-mri-based-brachytherapy-program-for-cervical-cancer
#13
REVIEW
Matthew M Harkenrider, Steven M Shea, Abbie M Wood, Bonnie Chinsky, Amishi Bajaj, Michael Mysz, Joseph H Yacoub, Ari Goldberg, Margaret Liotta, Ronald Potkul, Murat Surucu, John Roeske, William Small
PURPOSE: Adaptive magnetic resonance imaging (MRI)-based brachytherapy results in improved local control and decreased high-grade toxicities compared to historical controls. Incorporating MRI into the workflow of a department can be a major challenge when initiating an MRI-based brachytherapy program. This project aims to describe the goals, challenges, and solutions when initiating an MRI-based cervical cancer brachytherapy program at our institution. MATERIAL AND METHODS: We describe the 6-month multi-disciplinary planning phase to initiate an MRI-based brachytherapy program...
April 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28533403/reassessment-of-20th-century-global-mean-sea-level-rise
#14
Sönke Dangendorf, Marta Marcos, Guy Wöppelmann, Clinton P Conrad, Thomas Frederikse, Riccardo Riva
The rate at which global mean sea level (GMSL) rose during the 20th century is uncertain, with little consensus between various reconstructions that indicate rates of rise ranging from 1.3 to 2 mm⋅y(-1) Here we present a 20th-century GMSL reconstruction computed using an area-weighting technique for averaging tide gauge records that both incorporates up-to-date observations of vertical land motion (VLM) and corrections for local geoid changes resulting from ice melting and terrestrial freshwater storage and allows for the identification of possible differences compared with earlier attempts...
May 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28532494/insecticide-treated-durable-wall-lining-itwl-future-prospects-for-control-of-malaria-and-other-vector-borne-diseases
#15
REVIEW
Louisa A Messenger, Mark Rowland
While long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the cornerstones of malaria vector control throughout sub-Saharan Africa, there is an urgent need for the development of novel insecticide delivery mechanisms to sustain and consolidate gains in disease reduction and to transition towards malaria elimination and eradication. Insecticide-treated durable wall lining (ITWL) may represent a new paradigm for malaria control as a potential complementary or alternate longer-lasting intervention to IRS...
May 22, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28532202/experiences-of-establishing-an-academic-early-phase-clinical-trials-unit
#16
Sarah R Brown, Debbie Sherratt, Gill Booth, Julia Brown, Fiona Collinson, Walter Gregory, Louise Flanagan
BACKGROUND: Early phase trials are essential in drug development, determining appropriate dose levels and assessing preliminary activity. These trials are undertaken by industry and academia, with increasing collaborations between the two. There is pressure to perform these trials quickly, safely, and robustly. However, there are inherent differences between developing and managing early phase, compared to late phase, drug trials. This article describes an approach to establishing an academically led early phase trial portfolio, highlighting lessons learned and sharing experiences...
May 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28531888/right-trac%C3%A2-post-hospitalization-care-transitions-program-to-reduce-readmissions-for-hemodialysis-patients
#17
Rebecca L Wingard, Kathryn McDougall, Billie Axley, Andrew Howard, Cathleen O'Keefe, Nancy Armistead, Janet R Lynch, Sophia Rosen, Len Usvyat, Franklin W Maddux
BACKGROUND: Hemodialysis (HD) patients have high hospitalization rates. This nonrandomized trial tested the effect of a bundle of renal-specific "Right TraC™" strategies on 30-day all-cause readmission rates and, secondarily, 90-day readmissions and overall admissions among HD patients. METHODS: Twenty-six Fresenius clinics in West Virginia, Ohio, and Kentucky participated in the interventions. Eighteen matched clinics served as controls; intervention clinics also served as their own controls...
May 23, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28530835/on-the-formation-of-epitaxially-connected-quantum-dot-solids-nucleation-and-coherent-phase-transition
#18
Kevin Whitham, Tobias Hanrath
The formation of epitaxially connected quantum dot solids involves a complex interplay of interfacial assembly, surface chemistry, and irreversible directed attachment. We describe the basic mechanism in context of a coherent phase transition with distinct nucleation and propagation steps. The proposed mechanism explains how defects in the pre-assembled structure influence nucleation and how basic geometric relationships govern the transformation from hexagonal assemblies of isolated dots to interconnected solids with square symmetry...
May 22, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28530813/enhanced-sampling-of-phase-transitions-in-coarse-grained-lipid-bilayers
#19
David N Stelter, Tom Keyes
Freezing and melting of dipalmitoylphosphatidylcholine (DPPC) bilayers are simulated in both the explicit (Wet) and implicit solvent (Dry) coarse-grained MARTINI force fields with enhanced sampling, via the isobaric, molecular dynamics version of the generalized replica exchange method (gREM). Phase transitions are described with the entropic viewpoint, based upon the statistical temperature as a function of enthalpy, TS(H) = 1/(dS(H)/dH), where S is the configurational entropy. Bilayer thickness, area per lipid, and the second-rank order parameter (P2) are calculated vs temperature in the transition range...
May 22, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28530810/seleniranium-ions-undergo-%C3%AF-ligand-exchange-via-an-associative-mechanism-in-the-gas-phase
#20
Shea Fern Lim, Benjamin Leigh Harris, George N Khairallah, Evan John Bieske, Philippe Maître, Gabriel da Silva, Brian D Adamson, Michael S Scholz, Neville J A Coughlan, Richard A J O'Hair, Michael Rathjen, Daniel Stares, Jonathan M White
Collision-induced dissociation mass spectrometry of the ammonium ions 4a and 4b results in the formation of the seleniranium ion 5, the structure and purity of which was verified using gas phase infra-red spectroscopy coupled to mass spectrometry, and gas phase ion-mobility measurements. Ion-molecule reactions between the ion 5 (m/z = 261) and cyclopentene, cyclohexene, cycloheptene and cyclooctene, resulted in the formation of the seleniranium ions 7 (m/z = 225), 6 (m/z = 239), 8 (m/z = 253), and 9 (m/z = 267) respectively...
May 22, 2017: Journal of Organic Chemistry
keyword
keyword
82236
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"