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https://www.readbyqxmd.com/read/28444432/childhood-growth-predicts-higher-bone-mass-and-greater-bone-area-in-early-old-age-findings-among-a-subgroup-of-women-from-the-helsinki-birth-cohort-study
#1
T M Mikkola, M B von Bonsdorff, C Osmond, M K Salonen, E Kajantie, C Cooper, M J Välimäki, J G Eriksson
We examined the associations between childhood growth and bone properties among women at early old age. Early growth in height predicted greater bone area and higher bone mineral mass. However, information on growth did not improve prediction of bone properties beyond that predicted by body size at early old age. INTRODUCTION: We examined the associations between body size at birth and childhood growth with bone area, bone mineral content (BMC), and areal bone mineral density (aBMD) in early old age...
April 25, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28444388/apoe%C3%AE%C2%B54-genotype-and-hypertension-modify-8-year-cortical-thinning-five-occasion-evidence-from-the-seattle-longitudinal-study
#2
Philippe Rast, Kristen M Kennedy, Karen M Rodrigue, Paul R A W Robinson, Alden L Gross, Donald G McLaren, Tom Grabowski, K Warner Schaie, Sherry L Willis
We investigated individual differences in longitudinal trajectories of brain aging in cognitively normal healthy adults from the Seattle Longitudinal Study covering 8 years of longitudinal change (across 5 occasions) in cortical thickness in 249 midlife and older adults (52-95 years old). We aimed to understand true brain change; examine the influence of salient risk factors that modify an individual's rate of cortical thinning; and compare cross-sectional age-related differences in cortical thickness to longitudinal within-person cortical thinning...
April 21, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28443220/do-factors-associated-self-rated-good-health-and-their-influences-differ-between-males-and-females-across-different-age-groups-in-korean-and-australia
#3
Hyo Young Lee, Stephanie Doris Short
OBJECTIVES: This was a comparative study between Australia and Korea that investigated whether and to what extent factors related to self-rated good health (SRGH) differ by gender among age groups. METHODS: This study was a secondary analysis of data that were collected in nationally representative, cross-sectional, and population-based surveys. We analyzed Australian and Korean participants > 20 years of age using 2011 data from the Australian National Nutritional Physical Activity Survey (n = 9,276) and the Korean National Health and Nutritional Examination Survey (n = 5,915)...
February 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/28442898/medication-regimen-complexity-in-ambulatory-older-adults-with-heart-failure
#4
Michael R Cobretti, Robert L Page, Sunny A Linnebur, Kimberly M Deininger, Amrut V Ambardekar, JoAnn Lindenfeld, Christina L Aquilante
PURPOSE: Heart failure prevalence is increasing in older adults, and polypharmacy is a major problem in this population. We compared medication regimen complexity using the validated patient-level Medication Regimen Complexity Index (pMRCI) tool in "young-old" (60-74 years) versus "old-old" (75-89 years) patients with heart failure. We also compared pMRCI between patients with ischemic cardiomyopathy (ISCM) versus nonischemic cardiomyopathy (NISCM). PATIENTS AND METHODS: Medication lists were retrospectively abstracted from the electronic medical records of ambulatory patients aged 60-89 years with heart failure...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28442844/a-rare-case-of-bilateral-morgagni-s-hernia-with-intestinal-obstruction-and-malrotation-of-the-gut-in-an-adult-patient-with-severe-osteogenesis-imperfecta-presenting-as-severe-respiratory-distress
#5
S Y Kulgod, Amit Shivashankar Ammanagi, Pradeep Vagarali, Ravi Patil
Osteogenesis imperfecta (OI) is associated with congenital inguinal hernia that can occur due to genetic mutation. Morgagni's hernia is a rare congenital diaphragmatic herniation and is usually diagnosed in childhood. We present a case of an 18-year-old male presenting with bilateral Morgagni's hernia with intestinal obstruction with osteogenesis imperfecta with malrotation of the gut.
April 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28442339/neural-evidence-for-the-subliminal-processing-of-facial-trustworthiness-in-infancy
#6
Sarah Jessen, Tobias Grossmann
Face evaluation is thought to play a vital role in human social interactions. One prominent aspect is the evaluation of facial signs of trustworthiness, which has been shown to occur reliably, rapidly, and without conscious awareness in adults. Recent developmental work indicates that the sensitivity to facial trustworthiness has early ontogenetic origins as it can already be observed in infancy. However, it is unclear whether infants' sensitivity to facial signs of trustworthiness relies upon conscious processing of a face or, similar to adults, occurs also in response to subliminal faces...
April 22, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28442319/a-rare-case-of-congenital-bronchoesophageal-fistula-in-an-adult
#7
Naohiro Taira, Hidenori Kawasaki, Eriko Atsumi, Tomonori Furugen, Takaharu Ichi, Kazuaki Kushi, Tomofumi Yohena, Motoo Baba, Tsutomu Kawabata
INTRODUCTION: When congenital bronchoesophageal fistulas exist without atresia of the esophagus, the diagnosis can be delayed, although symptoms may occur early following fistula development. Therefore, while they are usually found in infants, they can be extremely rarely found in adults. We herein report a rare case of bronchoesophageal fistula without atresia in an adult. CASE: An 69-year-old male presented to the outpatient clinic with a decades-long history of cough with expectoration immediately after taking food, especially liquids...
March 21, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28442236/red-blood-cell-membrane-omega-3-fatty-acid-levels-and-physical-performance-cross-sectional-data-from-the-mapt-study
#8
Bertrand Fougère, Philipe de Souto Barreto, Sabine Goisser, Gaëlle Soriano, Sophie Guyonnet, Sandrine Andrieu, Bruno Vellas
BACKGROUND & AIMS: Studies have shown that omega-3 polyunsaturated fatty acids (PUFAs) are associated with brain, cardiovascular and immune function, as well as physical performance and bone health in older adults. So far, few studies have highlighted the associations between PUFA status and performance-based tests of physical function. To study the associations between the omega-3 index (red blood cell (RBC) membrane content of omega-3 PUFAs, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) and physical performance measured with the Short Physical Performance Battery (SPPB) in a sample of community-dwelling older adults...
April 12, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28441903/age-criterion-flexibility-and-item-recognition
#9
Lione J North, Darlene Olfman, Daniel R Caldera, Emily Munoz, Leah L Light
We examined young and older adults' ability to flexibly adapt response criterion on a recognition test when the probability that a test item had been studied was cued by test color. One word color signaled that the probability of the test item being old was 70% and a second color signaled that the probability of the test item being new was 70%. Young and older adults demonstrated similar levels of criterion shifting in response to color cues. Moreover, although both young and older adults were slowed when test-item color incorrectly predicted test-item status, the extent of slowing did not differ across age group...
April 26, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/28441727/job-strain-and-casual-blood-pressure-distribution-looking-beyond-the-adjusted-mean-and-taking-gender-age-and-use-of-antihypertensives-into-account-results-from-elsa-brasil
#10
Leidjaira Lopes Juvanhol, Enirtes Caetano Prates Melo, Marilia Sá Carvalho, Dóra Chor, José Geraldo Mill, Rosane Härter Griep
Methodological issues are pointed to as the main sources of inconsistencies in studies about the association between job strain and blood pressure (BP)/hypertension. Our aim was to analyze the relationship between job strain and the whole BP distribution, as well as potential differences by gender, age, and use of antihypertensives. Additionally, we addressed issues relating to the operationalization of the exposure and outcome variables that influence the study of their inter-relations. We evaluated the baseline date of 12,038 participants enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) (2008-2010), a multicenter cohort study of 35-74-year-old civil servants...
April 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28441681/complications-and-mortality-following-one-to-two-level-anterior-cervical-fusion-for-cervical-spondylosis-in-patients-above-80-years-of-age
#11
Varun Puvanesarajah, Amit Jain, Adam L Shimer, Anuj Singla, Francis Shen, Hamid Hassanzadeh
STUDY DESIGN: A retrospective database review. OBJECTIVE: The aim of this study was to determine the complication and mortality rates in patients 80 years of age and older who were treated with anterior cervical fusion surgery and to compare these rates against those of other elderly patients. SUMMARY OF BACKGROUND DATA: Cervical spondylosis is frequently observed in the elderly and is the most common cause of myelopathy in older adults. With increasing life expectancies, a greater proportion of patients are being treated with spine surgery at a later age...
May 1, 2017: Spine
https://www.readbyqxmd.com/read/28441347/association-between-sleep-and-body-weight-a-panel-data-model-based-on-a-retrospective-longitudinal-cohort-of-chinese-infants
#12
Tingting Sha, Yan Yan, Xiao Gao, Shiting Xiang, Guangyu Zeng, Shiping Liu, Qiong He
The focus of this article is on sleep duration and sleep problems in infants and their association with body weight. A retrospective birth cohort of 519 infants was enrolled in a community-based study conducted in Changsha, China. Infant weight and other health-related information were collected during regular standard checkups at the Community Health Service Centers when infants were 1, 3, 6, 8, and 12 months old. The sleep duration and sleep problems of infants were assessed by maternal self-reports. Panel data model was used to evaluate the association of sleep duration and sleep problems with infant body weight...
April 25, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28441235/noninvasive-iphone-measurement-of-left-ventricular-ejection-fraction-using-intrinsic-frequency-methodology
#13
Niema M Pahlevan, Derek G Rinderknecht, Peyman Tavallali, Marianne Razavi, Thao T Tran, Michael W Fong, Robert A Kloner, Marie Csete, Morteza Gharib
OBJECTIVE: The study is based on previously reported mathematical analysis of arterial waveform that extracts hidden oscillations in the waveform that we called intrinsic frequencies. The goal of this clinical study was to compare the accuracy of left ventricular ejection fraction derived from intrinsic frequencies noninvasively versus left ventricular ejection fraction obtained with cardiac MRI, the most accurate method for left ventricular ejection fraction measurement. DESIGN: After informed consent, in one visit, subjects underwent cardiac MRI examination and noninvasive capture of a carotid waveform using an iPhone camera (The waveform is captured using a custom app that constructs the waveform from skin displacement images during the cardiac cycle...
April 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28441120/prevalence-of-trachoma-in-northern-benin-results-from-11-population-based-prevalence-surveys-covering-26-districts
#14
Amadou Alfa Bio, Pelagie M Boko, Yannelle A Dossou, Jean-Jacques Tougoue, Achille Kabore, Ignace Sounouvou, Jean-Eudes Biaou, Lionel Nizigama, Paul Courtright, Anthony W Solomon, Lisa Rotondo, Wilfrid Batcho, Dorothée Kinde-Gazard
AIMS: We sought to evaluate trachoma prevalence in all suspected-endemic areas of Benin. METHODS: We conducted population-based surveys covering 26 districts grouped into 11 evaluation units (EUs), using a two-stage, systematic and random, cluster sampling design powered at EU level. In each EU, 23 villages were systematically selected with population proportional to size; 30 households were selected from each village using compact segment sampling. In selected households, we examined all consenting residents aged one year or above for trichiasis, trachomatous inflammation - follicular (TF), and trachomatous inflammation - intense...
April 25, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28441047/distribution-of-t-cell-markers-cd4-and-cd8%C3%AE-in-lymphoid-organs-of-healthy-newborn-juvenile-and-adult-highland-plateau-yaks
#15
Qian Zhang, Kun Yang, Yufeng Huang, Junfeng He, Sijiu Yu, Yan Cui
OBJECTIVE: To investigate the distribution of T-cell markers (CD4 and CD8α) in lymphoid organs of newborn, juvenile, and adult yaks. ANIMALS: 15 healthy male yaks of various ages from highland plateaus. PROCEDURES: Yaks were allocated to groups on the basis of age (newborn [1 to 7 days old; n = 5], juvenile [5 to 7 months old; 5], and adult [3 to 4 years old; 5]). The thymus, spleen, 5 mesenteric lymph nodes, and 5 hemal nodes were harvested from each yak within 10 minutes after euthanasia...
May 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28440853/antibiotic-strategies-for-eradicating-pseudomonas-aeruginosa-in-people-with-cystic-fibrosis
#16
REVIEW
Simon C Langton Hewer, Alan R Smyth
BACKGROUND: Respiratory tract infection with Pseudomonas aeruginosa occurs in most people with cystic fibrosis. Once chronic infection is established, Pseudomonas aeruginosa is virtually impossible to eradicate and is associated with increased mortality and morbidity. Early infection may be easier to eradicate.This is an update of a Cochrane review first published in 2003, and previously updated in 2006, 2009 and 2014. OBJECTIVES: To determine whether antibiotic treatment of early Pseudomonas aeruginosa infection in children and adults with cystic fibrosis eradicates the organism, delays the onset of chronic infection, and results in clinical improvement...
April 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28439937/maternal-nutrient-restriction-during-pregnancy-and-lactation-leads-to-impaired-right-ventricular-function-in-young-adult-baboons
#17
Anderson H Kuo, Cun Li, Hillary F Huber, Matthias Schwab, Peter W Nathanielsz, Geoffrey D Clarke
Maternal nutrient restriction induces IUGR increasing later life chronic disease including cardiovascular dysfunction. Our left ventricular (LV) CMRI studies in IUGR baboons (8 M, 8 F, 5.7 years- human equivalent approximately 25 years), control offspring (8 M, 8 F, 5.6 years), and normal elderly (OLD) baboons (6 M, 6 F, mean 15.9 years) revealed long-term LV abnormalities in IUGR offspring. Although it is known that right ventricular (RV) function is dependent on LV health, the IUGR right ventricle (RV) remains poorly studied...
April 25, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28439807/generating-explanations-via-analogical-comparison
#18
Christian Hoyos, Dedre Gentner
Generating explanations can be highly effective in promoting learning in both adults and children. Our interest is in the mechanisms that underlie this effect and in whether and how they operate in early learning. In adult reasoning, explanation may call on many subprocesses-including comparison, counterfactual reasoning, and reasoning by exclusion; but it is unlikely that all these processes are available to young children. We propose that one process that may serve both children and adults is comparison. In this study, we asked whether children would use the results of a comparison experience when asked to explain why a model skyscraper was stable...
April 24, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28439627/nigral-injection-of-a-proteasomal-inhibitor-lactacystin-induces-widespread-glial-cell-activation-and-shows-various-phenotypes-of-parkinson-s-disease-in-young-and-adult-mouse
#19
Mari H Savolainen, Katrina Albert, Mikko Airavaara, Timo T Myöhänen
Proteinaceous inclusions, called Lewy bodies, are used as a pathological hallmark for Parkinson's disease (PD). Lewy bodies contain insoluble α-synuclein (aSyn) and many other ubiquitinated proteins, suggesting a role for protein degradation system failure in the PD pathogenesis. Indeed, proteasomal dysfunction has been linked to PD but commonly used in vivo toxin models, such as 6-OHDA or MPTP, do not have a significant effect on the proteasomal system or protein aggregation. Therefore, we wanted to study the characteristics of a proteasomal inhibitor, lactacystin, as a PD model on young and adult mice...
April 24, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28439220/pediatric-reference-intervals-for-transferrin-saturation-in-the-caliper-cohort-of-healthy-children-and-adolescents
#20
Victoria Higgins, Man Khun Chan, Khosrow Adeli
BACKGROUND: Transferrin saturation reference intervals specific for age and sex have not been previously reported for the pediatric population. The reference values for transferrin saturation have been previously reported to be lower in children compared to adults, caused by a combination of low serum iron and high serum transferrin levels in children, warranting specific reference intervals. Here we use the original iron and transferrin data from the CALIPER cohort to establish age- and sex-specific pediatric reference intervals for transferrin saturation...
March 2017: EJIFCC
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