Qiu Yin, Yucheng Luo, Xianglin Yu, Keke Chen, Wanlu Li, Hu Huang, Lin Zhang, Yinning Zhou, Benpeng Zhu, Zhichao Ma, Wenming Zhang
Cell-laden hydrogel fibers/tubules are one of the fundamentals of tissue engineering. They have been proven as a promising method for constructing biomimetic tissues, such as muscle fibers, nerve conduits, tendon and vessels, etc. However, current hydrogel fiber/tubule production methods have limitations in ordered cell arrangements, thus impeding the biomimetic configurations. Acoustic cell patterning is a cell manipulation method that has good biocompatibility, wide tunability, and is contact-free. However, there are few studies on acoustic cell patterning for fiber production, especially on the radial figure cell arrangements, which mimic many native tissue-like cell arrangements...
February 2, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)