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https://www.readbyqxmd.com/read/28727103/effects-of-dietary-calcium-fructoborate-supplementation-on-joint-comfort-and-flexibility-and-serum-inflammatory-markers-in-dogs-with-osteoarthritis
#1
A K Price, M R C de Godoy, T A Harper, K E Knap, S Joslyn, Z Pietrzkowski, B K Cross, K B Detweiler, K S Swanson
Our objective was to evaluate the short-term effects of calcium fructoborate (CFB) on gait, joint range of motion, serum inflammatory markers, and owner perception of pain in client-owned dogs. We used 59 osteoarthritic dogs with impairment, with dogs being randomly assigned to 4 treatments: placebo (60 mg fructose; = 15), low dose (69 mg CFB; = 14), high dose (127 mg CFB; = 14), or combination (69 mg CFB, 500 mg glucosamine hydrochloride and 200 mg chondroitin sulfate; = 16). Dogs up to 22.9 kg received 1 capsule/d, while dogs weighing 23 to 50 kg received 2 capsules/d...
July 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726244/computed-tomographic-morphometry-of-tympanic-bulla-shape-and-position-in-brachycephalic-and-mesaticephalic-dog-breeds
#2
Ben Mielke, Richard Lam, Gert Ter Haar
Anatomic variations in skull morphology have been previously described for brachycephalic dogs; however there is little published information on interbreed variations in tympanic bulla morphology. This retrospective observational study aimed to (1) provide detailed descriptions of the computed tomographic (CT) morphology of tympanic bullae in a sample of dogs representing four brachycephalic breeds (Pugs, French Bulldogs, English Bulldog, and Cavalier King Charles Spaniels) versus two mesaticephalic breeds (Labrador retrievers and Jack Russell Terriers); and (2) test associations between tympanic bulla morphology and presence of middle ear effusion...
July 20, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28711819/differentiation-potential-of-synoviocytes-derived-from-joints-with-cranial-cruciate-ligament-rupture-and-medial-patella-luxation-in-dogs
#3
H M Suranji Wijekoon, Kazuhide Toyota, Sangho Kim, Jing Fang, Eugene C Bwalya, Kenji Hosoya, Masahiro Okumura
The objective of this study was to assess the differentiation capability of synoviocytes derived from dogs with inflammatory joint conditions. Cranial cruciate ligament ruptured (CCLr) (n=12) and medial patella luxated (MPL) (n=10) knee joints of the dogs were used to collect the synovial membrane (SM). Synoviocytes were enzymatically released from the SM and analyzed by flow cytometry for specific cellular markers (CD44 and CD90) of mesenchymal stem cells (MSCs), while doing histopathology from another part of SM sections...
July 9, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28688157/the-application-of-3-dimensional-printing-for-preoperative-planning-in-oral-and-maxillofacial-surgery-in-dogs-and-cats
#4
Jenna N Winer, Frank J M Verstraete, Derek D Cissell, Steven Lucero, Kyriacos A Athanasiou, Boaz Arzi
OBJECTIVE: To describe the application of 3-dimensional (3D) printing in advanced oral and maxillofacial surgery (OMFS) and to discuss the benefits of this modality in surgical planning, student and resident training, and client education. STUDY DESIGN: Retrospective case series. ANIMALS: Client-owned dogs (n = 28) and cats (n = 4) with 3D printing models of the skulls. METHODS: The medical records of 32 cases with 3D printing prior to major OMFS were reviewed...
July 8, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28677167/anterior-femoral-bow-and-possible-effect-on-the-stifle-joint-a-comparison-between-humans-and-dogs
#5
M K Ocal, S S Sabanci, M Cobanoglu, M Enercan
The aim of the study was to compare the anterior bow of the femur between dogs and humans in terms of the possible impact on the stifle joint. The femoral radiographs obtained retrospectively were used to determine the angles and positions of the anterior bow in both dogs (n = 135) and humans (n = 57). Descriptive statistics and Pearson's correlation analysis were used for the statistical analyses of the variables. The mean anterior bow angle (ABA) was 18.3 ± 2.02° and 4.88 ± 1.24° in dogs and humans, respectively...
July 4, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28665533/radiographic-assessment-of-humeroulnar-congruity-in-a-medium-and-a-large-breed-of-dog
#6
Sofia Alves-Pimenta, Bruno Colaço, Armando M Fernandes, Lio Gonçalves, Jorge Colaço, Pedro Melo-Pinto, Mário M Ginja
Elbow joint incongruity is recognized as an important factor in the development, treatment, and prognosis of canine elbow dysplasia. Elbow incongruity has been measured based on radiographic joint space widths, however these values can be affected by the degree of elbow joint flexion. Recent studies have reported radiographic curvature radii as more precise measures of humeroulnar congruity in dogs. The aim of this prospective observational study was to describe radiographic curvature radii measured from flexed and extended elbow radiographs for a sample of dogs representing a medium breed (Portuguese Pointing Dog) and a large breed (Estrela Mountain Dog)...
June 30, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28654381/preclinical-multimodal-molecular-imaging-using-18-f-fdg-pet-ct-and-mri-in-a-phase-i-study-of-a-knee-osteoarthritis-in-in-vivo-canine-model
#7
Maria I Menendez, Bianca Hettlich, Lai Wei, Michael V Knopp
The aim of this study was to use a multimodal molecular imaging approach to serially assess regional metabolic changes in the knee in an in vivo anterior cruciate ligament transection (ACLT) canine model of osteoarthritis (OA). Five canine underwent ACLT in one knee and the contralateral knee served as uninjured control. Prior, 3, 6, and 12 weeks post-ACLT, the dogs underwent (18)F-fluoro-d-glucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) and magnetic resonance imaging (MRI). The MRI was coregistered with the PET/CT, and 3-dimensional regions of interest (ROIs) were traced manually and maximum standardized uptake values (SUVmax) were evaluated...
January 1, 2017: Molecular Imaging
https://www.readbyqxmd.com/read/28651457/metallosis-in-a-dog-as-a-long-term-complication-following-total-hip-arthroplasty
#8
Mallory J DiVincenzo, Galit H Frydman, Michael P Kowaleski, Charles R Vanderburg, Barry Lai, Trisha J Oura, Samuel H Jennings
Metallosis is the accumulation of metallic debris in soft tissues resulting from wear following total joint replacement. A dog was evaluated for lameness 4 years after total hip arthroplasty using a titanium alloy and cobalt chromium total hip system. Radiographs revealed severe acetabular component wear, implant-bone interface deterioration, and peri-acetabular osteolysis. During surgical revision, black periarticular tissue surrounded the implants. Histologically, there was fibrosis and granulomatous inflammation with abundant, intra- and extracellular, black, granular material and smaller amounts of clear punctate to acicular material...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28650238/three-dimensional-inverse-dynamics-of-the-forelimb-of-beagles-at-a-walk-and-trot
#9
Emanuel Andrada, Lars Reinhardt, Karin Lucas, Martin S Fischer
OBJECTIVE To perform 3-D inverse dynamics analysis of the entire forelimb of healthy dogs during a walk and trot. ANIMALS 5 healthy adult Beagles. PROCEDURES The left forelimb of each dog was instrumented with 19 anatomic markers. X-ray fluoroscopy was used to optimize marker positions and perform scientific rotoscoping for 1 dog. Inverse dynamics were computed for each dog during a walk and trot on the basis of data obtained from an infrared motion-capture system and instrumented quad-band treadmill. Morphometric data were obtained from a virtual reconstruction of the left forelimb generated from a CT scan of the same dog that underwent scientific rotoscoping...
July 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28634158/stem-cell-therapy-for-enhancement-of-bone-consolidation-in-distraction-osteogenesis-a-contemporary-review-of-experimental-studies
#10
Y Yang, S Lin, B Wang, W Gu, G Li
OBJECTIVES: Distraction osteogenesis (DO) mobilises bone regenerative potential and avoids the complications of other treatments such as bone graft. The major disadvantage of DO is the length of time required for bone consolidation. Mesenchymal stem cells (MSCs) have been used to promote bone formation with some good results. METHODS: We hereby review the published literature on the use of MSCs in promoting bone consolidation during DO. RESULTS: Studies differed in animal type (mice, rabbit, dog, sheep), bone type (femur, tibia, skull), DO protocols and cell transplantation methods...
June 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28622089/large-animal-models-of-meniscus-repair-and-regeneration-a-systematic-review-of-the-state-of-the-field
#11
Sonia Bansal, Niobra M Keah, Alexander L Neuwirth, Olivia O'Reilly, Feini Qu, Breanna Seiber, Sai Mandalapu, Robert Leon Mauck, Miltiadis Zgonis
Injury to the meniscus is common but few viable strategies exist for its repair or regeneration. To address this, animal models have been developed to translate new treatment strategies towards the clinic. However, there is not yet a regulatory document guiding such studies. The purpose of this study was to carry out a systematic review of the literature on meniscus treatment methods and outcomes to define the state of the field. Public databases were queried using search terms related to animal models and meniscus injury and/or repair over the years 1980-2015...
June 16, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28621599/comparison-of-ultrasonography-and-magnetic-resonance-imaging-to-arthroscopy-for-diagnosing-medial-meniscal-lesions-in-dogs-with-cranial-cruciate-ligament-deficiency
#12
Samuel P Franklin, James L Cook, Cristi R Cook, Layla S Shaikh, Kevin M Clarke, Shannon P Holmes
OBJECTIVE To compare the accuracy of ultrasonography and MRI for diagnosing medial meniscal lesions in dogs with cranial cruciate ligament (CCL) deficiency. DESIGN Diagnostic test evaluation. ANIMALS 26 dogs (31 stifle joints) with CCL deficiency. PROCEDURES A single surgeon physically examined each dog and performed ultrasonography and arthroscopy of affected stifle joints to identify medial meniscal lesions. Video recordings of the arthroscopic procedure were saved and subsequently reviewed by the same surgeon and by a second surgeon working independently and blinded to results of all examinations...
July 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28620415/a-novel-surgical-technique-for-fixation-of-recurrent-acromioclavicular-dislocations-ac-dog-bone-technique-in-combination-with-autogenous-semitendinosus-tendon-graft
#13
Patrick Holweg, Wolfgang Pichler, Gerald Gruber, Ellen Tackner, Franz Josef Seibert, Patrick Sadoghi, Gloria Hohenberger
Various surgical techniques have been described for the fixation of acromioclavicular (AC) dislocations. However, recurrent dislocation is one of the main complications associated with the majority of these techniques. We report a case of postoperative AC joint redislocation. In order to overcome recurrent dislocation after revision surgery, a reconstruction of the conoid and trapezoid ligament with the use of a free tendon graft in combination with a FiberTape was provided within a novel surgical technique...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28585294/ichthyosis-fetalis-in-a-cross-bred-lamb
#14
Antonio Carlos Lopes Câmara, Pedro Augusto Cordeiro Borges, Silvano Alves Paiva, Felipe Pierezan, Benito Soto-Blanco
BACKGROUND: Ichthyosis is a dermatological disease characterized by varying degrees of generalized hyperkeratosis and alopecia. Two congenital forms of ichthyosis are recognized in animals: fetalis (IF) and congenita. The disease occurs rarely in cattle, swine, dogs, chickens and a goat; it has not been reported in sheep. HYPOTHESIS/OBJECTIVES: To provide clinical, laboratory and pathological assessments of a case of IF in a cross-bred lamb. ANIMALS: A male cross-bred lamb...
June 5, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28582983/occurrence-of-i-coxiella-burnetii-i-i-ehrlichia-canis-i-i-rickettsia-i-species-and-i-anaplasma-phagocytophilum-i-like-bacterium-in-ticks-collected-from-dogs-and-cats-in-south-africa
#15
Khethiwe Mtshali, Ryo Nakao, Chihiro Sugimoto, Oriel Thekisoe
Ticks are major vectors of arthropod-borne infections and transmit a wide variety of zoonotic pathogens. This study was conducted mainly to determine the occurrence of canine tick-borne bacterial and rickettsial pathogens especially those with zoonotic potential. We examined 276 Rhipicephalus sanguineus, 38 Haemaphysalis elliptica and 4 Amblyomma hebraeum ticks from 90 dogs and 4 cats from the Free State, KwaZulu-Natal, North West and Mpumalanga provinces. DNA of Coxiella burnetii (41%), Ehrlichia or Anaplasma (18%), Rickettsia spp...
May 19, 2017: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/28576273/femoral-head-and-neck-excision
#16
REVIEW
Tisha A M Harper
Femoral head and neck excision is a surgical procedure that is commonly performed in small animal patients. It is a salvage procedure that is done to relieve pain in the coxofemoral joint and restore acceptable function of the limb. Femoral head and neck excision is most commonly used to treat severe osteoarthritis in the coxofemoral joint and can be done in dogs and cats of any size or age. The procedure should not be overused and ideally should not be done when the integrity of the coxofemoral joint can be restored...
July 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28576272/juvenile-pubic-symphysiodesis
#17
REVIEW
Kathleen A Linn
In properly selected dogs, juvenile pubic symphysiodesis improves joint congruity, decreases hip laxity, and can reverse or prevent progression of degenerative joint disease in the hips. To be effective, surgery must be done at a young age and in hips that are only mildly to moderately lax. Juvenile pubic symphysiodesis is best viewed more as a preemptive procedure than as a strictly therapeutic one. Dogs considered to be at risk for hip dysplasia should be screened with Ortolani testing at 12 weeks of age, with further imaging and perhaps surgery to follow for those who have a positive Ortolani sign...
July 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28576271/physical-rehabilitation-for-the-management-of-canine-hip-dysplasia
#18
REVIEW
David L Dycus, David Levine, Denis J Marcellin-Little
Hip dysplasia is among the most common orthopedic conditions affecting dogs. Joint laxity is responsible for abnormal development of the femoral head and acetabulum, leading to excessive wear of the articular cartilage. Wear leads to secondary osteoarthritis. Rehabilitation is either conservative or after surgical management. Conservative rehabilitation therapies are directed at decreasing pain, improving hip range of motion (ROM), and building or maintaining muscle mass. Postoperatively, rehabilitation focuses on decreasing postoperative pain and inflammation, improving comfort and limb use, and protecting the surgical site...
July 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28576270/conservative-management-of-hip-dysplasia
#19
REVIEW
Tisha A M Harper
Hip dysplasia (HD) is a common orthopedic condition seen in small animal patients that leads to osteoarthritis of the coxofemoral joint. The disease can be managed conservatively or surgically. The goals of surgical treatment in the immature patient are to either prevent the clinical signs of HD or to prevent or slow the progression of osteoarthritis. In mature patients surgery is used as a salvage procedure to treat debilitating osteoarthritis. Conservative management can be used in dogs with mild or intermittent clinical signs and includes nutritional management and weight control, exercise modification, physical rehabilitation, pain management and disease-modifying agents...
July 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28569198/determination-of-reference-values-and-frequency-of-occurrence-of-patella-alta-in-german-shepherd-dogs-a-retrospective-study
#20
Anna Łojszczyk-Szczepaniak, Piotr Silmanowicz, Renata Komsta, Zbigniew Osiński
BACKGROUND: Patella alta and patella baja are important conditions underlying a predisposition to many joint diseases, including patellar luxation and patellar chondromalacia of the articular cartilage. The frequencies of patella alta and patella baja have not yet been determined. The objectives of this study were to determine the frequency of patella alta and to determine reference values to the position of the vertical patella according to two modified techniques of the Insall-Salvati method in a group of 65 German shepherd dogs (115 stifle joints)...
May 31, 2017: Acta Veterinaria Scandinavica
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