keyword
https://read.qxmd.com/read/37526935/an-intensive-18f-fludeoxyglucose-positron-emission-tomography-with-computed-tomography-based-strategy-of-follow-up-in-patients-treated-for-head-and-neck-squamous-cell-carcinoma-who-are-clinically-asymptomatic
#21
JOURNAL ARTICLE
Jean-Christophe Leclère, Camille Clément, Romain Le Pennec, Clementine Maheo, Dorothy M Gujral, Ulrike Schick, Grégoire Le Gal, Remi Marianowski, Pierre-Yves Salaun, Ronan Abgral
IMPORTANCE: Patients with head and neck squamous cell carcinoma (HNSCC) have a significant risk of locoregional recurrence within the first 2 years, with approximately two-thirds of patients experiencing such recurrence. While early recurrence detection may be associated with improved patient outcomes, the association of such detection with survival remains uncertain. OBJECTIVE: To investigate the association of an intensive posttreatment follow-up strategy using 18F-fludeoxyglucose-positron emission tomography with computed tomography (18FDG-PET/CT) with survival among patients with HNSCC...
August 1, 2023: JAMA Network Open
https://read.qxmd.com/read/37388440/radiometal-chelators-for-infection-diagnostics
#22
JOURNAL ARTICLE
Asma Akter, Oliver Lyons, Varun Mehra, Heather Isenman, Vincenzo Abbate
Infection of native tissues or implanted devices is common, but clinical diagnosis is frequently difficult and currently available noninvasive tests perform poorly. Immunocompromised individuals (for example transplant recipients, or those with cancer) are at increased risk. No imaging test in clinical use can specifically identify infection, or accurately differentiate bacterial from fungal infections. Commonly used [18 F]fluorodeoxyglucose (18FDG) positron emission computed tomography (PET/CT) is sensitive for infection, but limited by poor specificity because increased glucose uptake may also indicate inflammation or malignancy...
January 9, 2023: Front Nucl Med
https://read.qxmd.com/read/37329519/safety-and-feasibility-clinical-trial-of-nucleus-accumbens-deep-brain-stimulation-for-treatment-refractory-opioid-use-disorder
#23
JOURNAL ARTICLE
Ali R Rezai, James J Mahoney, Manish Ranjan, Marc W Haut, Wanhong Zheng, Laura R Lander, James H Berry, Daniel L Farmer, Jennifer L Marton, Padma Tirumalai, Ashley Mears, Daisy G Y Thompson-Lake, Victor S Finomore, Pierre-François D'Haese, Will M Aklin, David T George, John D Corrigan, Sally L Hodder
OBJECTIVE: There were more than 107,000 drug overdose deaths in the US in 2021, the most ever recorded. Despite advances in behavioral and pharmacological treatments, over 50% of those receiving treatment for opioid use disorder (OUD) experience drug use recurrence (relapse). Given the prevalence of OUD and other substance use disorders (SUDs), the high rate of drug use recurrence, and the number of drug overdose deaths, novel treatment strategies are desperately needed. The objective of this study was to evaluate the safety and feasibility of deep brain stimulation (DBS) targeting the nucleus accumbens (NAc)/ventral capsule (VC) and potential impact on outcomes in individuals with treatment-refractory OUD...
January 1, 2024: Journal of Neurosurgery
https://read.qxmd.com/read/37329365/precision-targeting-in-prediction-for-rtms-clinical-outcome-in-depression-what-about-sgacc-lateralization-metabolic-connectivity-and-the-potential-role-of-the-cerebellum
#24
JOURNAL ARTICLE
Guo-Rong Wu, Chris Baeken
Predicting clinical response to repetitive transcranial magnetic stimulation (rTMS) in medication-resistant depression (MRD) has gained great importance in recent years. Mainly, the right subgenual anterior cingulate cortex (sgACC) functional connectivity has been put forward as biomarker in relation to rTMS clinical outcome. Even though the left and right sgACC may have different neurobiological functions, little is known about the possible lateralized predictive role of the sgACC in rTMS clinical outcome...
June 17, 2023: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/37237443/diagnostic-and-management-roles-of-fdg-pet-ct-imaging-in-post-transplant-lympho-proliferation-in-pediatric-heart-transplantation
#25
JOURNAL ARTICLE
Abdel-Karim Brown, Jennifer Carapellucci, Benjamin Oshrine, Anthony Gomez, Avner Meoded, Alfred Asante-Korang
BACKGROUND: Post-transplant lymphoproliferative disorder (PTLD) is a serious complication of pediatric heart transplant (PHTx). 18F-FDG PET/CT has been used to differentiate early lympho-proliferation from more advanced PTLD. We report our experience with PET/CT in the management of PTLD following PHTx. METHODS: This was a retrospective study of 100 consecutive PHTx recipients at our institution between 2004 and 2018. Patients who underwent PET/CT or conventional CT scans to evaluate for PTLD or high Epstein-Barr viral load were included...
May 26, 2023: Clinical Transplantation
https://read.qxmd.com/read/37207149/lipid-metabolism-marker-cd36-is-associated-with-18-fdg-pet-ct-false-negative-lymph-nodes-in-head-and-neck-squamous-cell-carcinoma
#26
JOURNAL ARTICLE
Xiaoyan Meng, Jingjing Sun, Feng Xu, Zhonglong Liu, Yue He
BACKGROUND: Lymph node metastasis frequently occurs in head and neck squamous cell carcinoma (HNSCC) patients, and [18 F] fluorodeoxyglucose positron emission tomography with computed tomography (18 FDG-PET/CT) examination for lymph node metastasis could result in false negativity and delay following treatment. However, the mechanism and resolution for 18 FDG-PET/CT false negatives remain unclear. Our study was aim to found biomarkers for false negativity and true positivity from a metabolic perspective...
2023: Frontiers in Oncology
https://read.qxmd.com/read/37115915/washout-computed-tomography-discriminates-pulmonary-fat-poor-hamartomas-from-neuroendocrine-neoplasms-a-simple-method-in-the-radiomics-era
#27
JOURNAL ARTICLE
Luca Volterrani, Armando Perrella, Giulio Bagnacci, Nunzia Di Meglio, Vito Di Martino, Paolo Bertelli, Cristiana Bellan, Maria A Mazzei, Luca Luzzi
PURPOSE: Pulmonary hamartomas (HAs) and neuroendocrine neoplasms (NENs) are often impossible to discriminate using high-resolution computed tomography (CT) as they share morphologic features. This challenge makes differential diagnosis crucial as HAs are invariably benign, whereas NENs must be considered malignant, thus requiring them to be evaluated for surgical excision.Our aim was, therefore, to develop a simple method to discriminate between pulmonary "fat-poor" HAs and NENs using contrast-enhanced CT (CECT)...
April 13, 2023: Journal of Thoracic Imaging
https://read.qxmd.com/read/37092877/impact-of-routine-preoperative-18-fdg-pet-ct-on-the-surgical-management-of-primary-colorectal-cancer
#28
JOURNAL ARTICLE
Mónica Mogollón-González, Raquel Conde-Muiño, Antonio Rodríguez-Fernández, Mar Navarro-Pelayo, Mireia Domínguez-Bastante, Pablo Palma
OBJECTIVES: Determine the usefulness of [18F]-fluorodeoxyglucose positron emission tomography/computed tomography (18 FDG-PET/CT) in the preoperative setting of colorectal cancer (CRC), assessing its impact on changes in management strategy. METHODS: Retrospective study of CRC patients who underwent preoperative 18 FDG-PET/CT and CT staging scans in a single referral center. The agreement between 18 FDG-PET/CT, contrast-enhanced CT, and colonoscopy for the surgical location was compared using the κ coefficient...
August 2023: Journal of Surgical Oncology
https://read.qxmd.com/read/37038297/volumetric-modulated-arc-radiotherapy-efficacy-after-double-recurrences-of-cardiac-sarcoma
#29
Antonio Rosario Pisani, Angela Sardaro, Nicola Maggialetti, Corinna Altini, Dino Rubini, Paolo Mammucci, Giuseppe Rubini
BACKGROUND: Volumetric Modulated Arc Therapy (VMAT) has recently become a pivotal treatment of oncological diseases due to the high-precise delineation of target volume contours with sparing organs at risk. This procedure requires a high level of experience and precision and is achievable only with advanced diagnostic support. Magnetic Resonance (MRI) and multimodality imaging, such as 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT), are fundamental in implementing radiotherapy guidance...
April 10, 2023: Current medical imaging
https://read.qxmd.com/read/36934353/-our-experience-with-the-treatment-of-hodgkin-lymphoma-patients
#30
JOURNAL ARTICLE
Árpád Illés, Ildikó Garai, Zsófia Miltényi
Overall and disease-free survival of Hodgkin lymphoma patients has improved significantly since the 2000s. This is due to the use of ABVD (adriamycin, bleomycin, vinblastine, dacarbazine) polychemotherapy and modern radiotherapy. In recent years, further diagnostic and therapeutic changes have been made, which further improve patients' survival. The most significant role in this is the improvement of diagnostics, such as the 18FDG-PET/CT, which is now routinely used repeatedly during treatment, and the response-adapted treatment(s) based on it...
March 19, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36876696/relationship-between-pet-ct-images-and-kras-gene-mutations-in-colorectal-cancer-in-vietnamese-patients
#31
JOURNAL ARTICLE
N V Dan, P C Phuong, P V Thai, N H Nguyen, N T Loi, B T Cong
OBJECTIVE: We conducted this study to determine the relationship among standardized uptake value (SUV), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) indexes of Flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography18 (FDG-PET/CT) imaging and Kirsten rat sarcoma (KRAS) gene mutations in colorectal cancer (CRC). PATIENTS AND METHODS: This cross-sectional study was conducted in Bach Mai Hospital from 2020 to 2022. It included newly diagnosed CRC patients who underwent PET/CT examination prior to primary tumor resection...
February 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/36866659/the-role-of-pet-ct-in-disease-activity-assessment-in-patients-with-large-vessel-vasculitis
#32
REVIEW
Elena Galli, Nicolò Pipitone, Carlo Salvarani
PURPOSE OF REVIEW: The aim of this article was to review the recent contributions on the role of PET in assessing disease activity in patients with large-vessel vasculitis (giant cell arteritis and Takayasu arteritis). RECENT FINDINGS: 18 FDG (fluorodeoxyglucose) vascular uptake in large-vessel vasculitis at PET shows moderate correlation with clinical indices, laboratory markers and signs of arterial involvement at morphological imaging. Limited data may suggest that 18 FDG (fluorodeoxyglucose) vascular uptake could predict relapses and (in Takayasu arteritis) the development of new angiographic vascular lesions...
May 1, 2023: Current Opinion in Rheumatology
https://read.qxmd.com/read/36798817/survival-effect-of-pre-rt-pet-ct-on-cervical-cancer-image-guided-intensity-modulated-radiation-therapy-era
#33
JOURNAL ARTICLE
Chih-Hsiung Su, Wan-Ming Chen, Mingchih Chen, Ben-Chang Shia, Szu-Yuan Wu
CONDENSED ABSTRACT: No large-scale, well-designed randomized study with a long-term follow-up has evaluated the survival effect of pretreatment 18-fluorodeoxyglucose positron emission tomography-computed tomography (18 FDG-PET-CT) on patients with stage IB-IVA cervical cancer receiving image-guided intensity-modulated radiation therapy (IG-IMRT). This is the first head-to-head propensity score-matched, nationwide population-based cohort study evaluating this survival effect. The results revealed that pretreatment 18 FDG-PET-CT might be associated with longer survival in patients with stage IB-IVA cervical cancer receiving radiotherapy or concurrent chemoradiotherapy, especially in the IG-IMRT era...
2023: Frontiers in Oncology
https://read.qxmd.com/read/36782296/pre-ccrt-18-fluorodeoxyglucose-pet-ct-improves-survival-in-patients-with-advanced-stages-p16-negative-oropharyngeal-squamous-cell-carcinoma-via-accurate-radiation-treatment-planning
#34
RANDOMIZED CONTROLLED TRIAL
Tsung-Ming Chen, Wan-Ming Chen, Mingchih Chen, Ben-Chang Shia, Szu-Yuan Wu
PURPOSE: No large-scale prospective randomized study with a long-term follow-up period has evaluated the survival outcomes of preconcurrent chemoradiotherapy (CCRT) 18-fluorodeoxyglucose positron emission tomography-computed tomography (18 FDG PET-CT) in patients with non-human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC). PATIENTS AND METHODS: We included patients with stage I-IVA p16-negative OPSCC receiving definitive CCRT and categorized them into two groups according to pre-CCRT 18 FDG PET-CT and compared their outcomes: the case group consisted of patients who underwent pre-CCRT 18 FDG PET-CT, whereas the comparison group consisted of patients who did not receive pre-CCRT 18 FDG PET-CT...
February 13, 2023: Journal of Otolaryngology—Head & Neck Surgery
https://read.qxmd.com/read/36776061/longitudinal-spatial-relationships-between-atrophy-and-hypometabolism-across-the-alzheimer-s-disease-continuum
#35
JOURNAL ARTICLE
Jane Stocks, Ashley Heywood, Karteek Popuri, Mirza Faisal Beg, Howie Rosen, Lei Wang
BACKGROUND: The A/T/N framework allows for the assessment of pathology-specific markers of MRI-derived structural atrophy and hypometabolism on 18FDG-PET. However, how these measures relate to each other locally and distantly across pathology-defined A/T/N groups is currently unclear. OBJECTIVE: To determine the regions of association between atrophy and hypometabolism in A/T/N groups both within and across time points. METHODS: We examined multivariate multimodal neuroimaging relationships between MRI and 18FDG-PET among suspected non-Alzheimer's disease pathology (SNAP) (A-T/N+; n = 14), Amyloid Only (A+T-N-; n = 24) and Probable AD (A+T+N+; n = 77) groups...
February 6, 2023: Journal of Alzheimer's Disease: JAD
https://read.qxmd.com/read/36762741/relationship-between-histopathological-features-of-non-infectious-aortitis-and-the-results-of-pre-operative-18f-fdg-pet-ct-a-retrospective-study-of-16-patients
#36
JOURNAL ARTICLE
Simon Parreau, Olivier Espitia, Michael S Bold, Livia M Frota Lima, Guillaume Lades, Mélanie Bois, Morgane Assaraf, David Saadoun, Matthew J Koster, Kim-Heang Ly, Cornelia M Weyand, Kenneth J Warrington, Eric Liozon
OBJECTIVES: To describe the characteristics of 18F-fluorodeoxyglucose positron-emission tomography/computed-tomography (18FDG-PET/CT) findings before surgery in patients with active, histologically confirmed aortitis, and to correlate the degree of arterial wall inflammation with PETVAS score. METHODS: This was a multiple-centre retrospective study including cases with histologically proven active, non-infectious aortitis who had a 18FDG-PET/CT performed within one year before surgery for aneurysm repair...
February 1, 2023: Clinical and Experimental Rheumatology
https://read.qxmd.com/read/36723883/18fdg-pet-ct-tumoral-and-neurologic-therapeutic-response-in-a-case-of-anti-gababr-paraneoplastic-limbic-encephalitis
#37
JOURNAL ARTICLE
Eric Ouvrard, Paul Voulleminot, Bertrand Mennecier, Caroline Bund, Izzie Jacques Namer
A 70-year-old man with a history of small cell lung carcinoma 2 years earlier was addressed for the suspicion of a paraneoplastic limbic encephalitis. Brain 18FDG PET/CT revealed a bilateral amygdalian and hippocampal hypermetabolism, confirming a limbic encephalitis, and concurrent whole-body 18FDG PET/CT showed a small cell lung carcinoma plurifocal metastatic recurrence, consistent with a paraneoplastic limbic encephalitis. 18FDG PET/CT follow-up under chemotherapy revealed an almost complete normalization of brain metabolism and a partial metabolic response of the metastatic recurrence, consistent with the good clinical neurological evolution of the patient...
March 1, 2023: Clinical Nuclear Medicine
https://read.qxmd.com/read/36722353/incidence-and-oncological-implication-of-adrenal-incidentalomas-in-esophageal-cancer-patients
#38
JOURNAL ARTICLE
J R van Doesburg, D M Voeten, M C Kalff, M I van Berge Henegouwen, S Jol, J E van den Bergh, A F Engelsman, S S Gisbertz, F Daams
Adrenal incidentalomas are regularly encountered during imaging for esophageal cancer patients, but their oncological significance remains unknown. This study aimed to describe the incidence and etiology of adrenal incidentalomas observed throughout the diagnostic workup. This retrospective cohort study included all esophageal cancer patients referred to or diagnosed in the Amsterdam UMC between January 2012 and December 2016. Radiology and multidisciplinary team meeting reports were reviewed for adrenal incidentalomas...
January 31, 2023: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/36607380/18f-fdg-and-68ga-fapi-04-pet-ct-in-evaluating-clear-cell-endometrial-cancer
#39
JOURNAL ARTICLE
Murat Yilmaz Kiran, Duygu Has Simsek, Yasemin Sanli, Serkan Kuyumcu
A 60-year-old woman diagnosed with clear cell endometrial carcinoma received neoadjuvant chemotherapy. However, the patient was inoperable and referred to our clinic to evaluate the extent of the disease. The patient underwent 18FDG PET/CT and 68Ga-FAPI (fibroblast activated protein inhibitor)-04 PET/CT scans. 68Ga-FAPI-04 PET/CT outperformed 18FDG PET/CT demonstrating higher uptake in the metastatic lesions.
February 1, 2023: Clinical Nuclear Medicine
https://read.qxmd.com/read/36602575/erdheim-chester-disease-diffusion-weighted-imaging-and-dynamic-contrast-enhanced-mri-provide-useful-information
#40
JOURNAL ARTICLE
Thomas Van Den Berghe, Esther Candries, Nicolas Everaert, Michael Saerens, Jo Van Dorpe, Koenraad Verstraete
This is, to our knowledge, the first case report with in-depth analysis of bone marrow and bone lesions with diffusion-weighted imaging and dynamic contrast-enhanced MRI in Erdheim-Chester disease to date. We present a case of a 70-year-old woman who was referred for an X-ray of the pelvis, right femur and right knee after complaints of migratory arthralgia in hip and knee five months after an initial hip and knee trauma. Bone lesions on X-ray were identified. This case report highlights the strength and complementary use of modern multimodality multiparametric imaging techniques in the clinical radiological manifestations of Erdheim-Chester disease, in the differential diagnosis and in treatment response assessment, which is classically performed using 18 FDG PET-CT...
January 5, 2023: Skeletal Radiology
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