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https://www.readbyqxmd.com/read/28323232/suspected-giant-cell-aortitis-from-multiple-aortic-structural-damage-to-fatal-listeria-sepsi-a-case-report
#1
Valeria Silvestri, Giacomo Isernia
Giant cell arteritis ( GCA) is an inflammatory vasculopathy affecting large and middle-sized vessels , specifically cranial arteries derived from carotid artery. Isolated extracranial vessel involvement can occur. Interest in extravascular manifestations is recently increasing because of diffusion of sensitive and specific imaging tools such as 18FDG PET TC . Patients have an increased relative risk of severe infection. Listeria monocytogenes infection risk is increased, and vascular system involvement and graft infection have been, even though rarely, reported...
March 16, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28320460/thyroid-incidentalomas-on-18fdg-pet-ct-a-metabolico-pathological-correlation
#2
N Hagenimana, J Dallaire, É Vallée, M Belzile
BACKGROUND: Thyroid incidentaloma is defined as an unsuspected thyroid lesion found on imaging study or while performing a surgery non-related to the thyroid gland. Most recent scientific literature tends to demonstrate a detection rate of 0.1-4.3% for incidental findings of thyroid focal uptake identified by (18)F-fluorodeoxyglugose Positron Emission Tomography with computed tomography ((18)FDG-PET/CT) initially prescribed for nonthyroid disease. From 10.3 to 80.0% of patients who underwent further evaluation are diagnosed with malignant lesions...
March 21, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28292379/18fdg-pet-ct-a-sensitive-tool-that-needs-better-users-understanding
#3
EDITORIAL
Maseeh uz Zaman, Nosheen Fatima
No abstract text is available yet for this article.
February 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28222142/evaluation-of-18-f-fluoro-2-deoxyglucose-fdg-positron-emission-tomography-computed-tomography-pet-ct-as-a-staging-and-monitoring-tool-for-dogs-with-stage-2-splenic-hemangiosarcoma-a-pilot-study
#4
Antonella Borgatti, Amber L Winter, Kathleen Stuebner, Ruth Scott, Christopher P Ober, Kari L Anderson, Daniel A Feeney, Daniel A Vallera, Joseph S Koopmeiners, Jaime F Modiano, Jerry Froelich
Positron Emission Tomography-Computed Tomography (PET-CT) is routinely used for staging and monitoring of human cancer patients and is becoming increasingly available in veterinary medicine. In this study, 18-fluorodeoxyglucose (18FDG)-PET-CT was used in dogs with naturally occurring splenic hemangiosarcoma (HSA) to assess its utility as a staging and monitoring modality as compared to standard radiography and ultrasonography. Nine dogs with stage-2 HSA underwent 18FDG-PET-CT following splenectomy and prior to commencement of chemotherapy...
2017: PloS One
https://www.readbyqxmd.com/read/28219319/biomarkers-in-alzheimer-s-disease-recent-update
#5
Sushil Sharma, Walter Lipincott
Alzheimer disease (AD) is an age-related neurodegenerative disorder, characterized by loss of memory and cognitive function. It is the common cause of dementia in elderly and is a global health concern as the population of people aged 85 and older, is growing alarmingly. Although pharmacotherapy for the treatment of AD has improved, lot of work remains to treat this devastating disease. AD pathology begins even before the onset of clinical symptoms. Because therapies could be more effective if implemented early in the disease progression, it is highly prudent to discover reliable biomarkers, to detect its exact pathophysiology during pre-symptomatic stage...
February 20, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28169837/survival-outcomes-for-patients-with-indeterminate-18fdg-pet-scan-for-extrahepatic-disease-before-liver-resection-for-metastatic-colorectal-cancer-a-retrospective-cohort-study-using-a-prospectively-maintained-database-to-analyze-survival-outcomes-for-patients
#6
Geoffrey Yuet Mun Wong, Rajiv Kumar, Carol Beeke, Shahid Ullah, John Chen, Christos Karapetis, Timothy Price, Rob Padbury
OBJECTIVE: The aim of this study was to evaluate overall survival (OS) and cancer recurrence for patients with indeterminate positron emission tomography (PET) scan for extrahepatic disease (EHD) before liver resection (LR) for colorectal liver metastases (CLMs). SUMMARY OF BACKGROUND DATA: Indeterminate EHD as determined by PET imaging indicates a probability of extrahepatic malignancy and potentially excludes patients from undergoing LR for CLM. METHODS: In a retrospective analysis of prospectively collected data from February 2006 to December 2014, OS for patients with indeterminate EHD on FDG-PET scan before LR for CLM was performed using standard survival analysis methods, including Kaplan-Meier estimator and Cox proportional hazard models for multivariate analyses...
February 6, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28133747/on-the-potential-for-rf-heating-in-mri-to-affect-metabolic-rates-and-18-fdg-signal-in-pet-mr-simulations-of-long-duration-maximum-normal-mode-heating
#7
Giuseppe Carluccio, Yu-Shin Ding, Jean Logan, Christopher M Collins
PURPOSE: To examine the possibility that MR-induced RF power deposition (SAR) and the resulting effects on temperature-dependent metabolic rates or perfusion rates might affect observed 18FDG signal in PET/MR. METHODS: Using numerical simulations of the SAR, consequent temperature increase, effect on rates of metabolism or perfusion, and [18FDG] throughout the body, we simulated the potential effect of maximum-allowable whole-body SAR for the entire duration of an hour-long PET/MR scan on observed PET signal for two different 18FDG injection times: one hour before onset of imaging and concurrent with the beginning of imaging...
February 2017: Medical Physics
https://www.readbyqxmd.com/read/28104743/active-brown-fat-during-18fdg-pet-ct-imaging-defines-a-patient-group-with-characteristic-traits-and-an-increased-probability-of-brown-fat-redetection
#8
Carlos Gerngroß, Johanna Schretter, Martin Klingenspor, Markus Schwaiger, Tobias Fromme
Brown adipose tissue (BAT) provides a means of non-shivering thermogenesis. In humans, active BAT can be visualized by (18)F-fluoro-desoxyglucose (FDG) uptake as detected by positron emission tomography (PET) combined with computer tomography (CT). The retrospective analysis of clinical scans is a valuable source to identify anthropometric parameters that influence BAT mass and activity and thus the potential efficacy of envisioned drugs targeting this tissue to treat metabolic disease. We analyzed 2854 FDG-PET/CT scans from 1644 patients and identified 98 scans from 81 patients with active BAT...
January 19, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28088309/-new-therapy-outlooks-in-hodgkin-lymphoma
#9
REVIEW
Cédric Rossi, René-Olivier Casasnovas
Classical Hodgkin lymphoma (HL) is a curable disease in 80% of advanced and 90% of localized stages. An improvement of the HL curability is still possible with the emergence of first-line therapy with a better balance between efficacy and toxicity and early identification patients with high risk of failure requiring specific treatment. 18FDG PET-CT gained a major role in the baseline staging and response assessment to HL treatment. The prognostic value of early PET-CT allowed to develop PET-CT guided therapies able to optimize the balance between efficacy and toxicity including the modulation of the chemotherapy intensity or the omission of radiotherapy for some localized diseases...
February 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28047500/su-g-iep4-07-feasibility-of-low-dose-18fdg-pet-in-pediatric-oncology-patients
#10
J Zhang, K Binzel, N C Hall, M Natwa, M I Knopp, M V Knopp
PURPOSE: To evaluate and demonstrate the feasibility of low dose FDG PET in pediatric oncology patients using virtual dose reduction as well as true patients PET/CT scans. METHODS: Wholebody 18F-FDG PET/CT of 39 clinical pediatric patients (0.16±0.06MBq/kg) were scanned on a Gemini TF 64 system at 75±5 min post FDG injection using 3min/bed. Based on the 180s/bed listmode PET data, subsets of total counts in 120s, 90s, 60s, 30s and 15s per bed position were extracted for PET reconstruction to simulate lower dose PET at 2/3th, 1/2th, 1/3th, 1/6th and 1/12th dose levels...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28027743/igg4-related-cardiovascular-disease-the-emerging-role-of-cardiovascular-imaging
#11
REVIEW
Sophie Mavrogeni, George Markousis-Mavrogenis, Genovefa Kolovou
Immunoglobulin 4-related disease (IgG4-related disease) is a systemic inflammatory disease that presents with increases of serum IgG4. It may affect various systems, including the cardiovascular (CV) system. Assessment of serum IgG4 levels and involved organ biopsy are necessary for diagnosis. IgG4-related disease is characterized by fibrosclerosis, lymphocytic infiltration and presence of IgG4-positive plasma cells. The disease usually responds to treatment with corticosteroids and/or immunosuppressive medication...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/27900757/unsuspected-axillary-lymph-node-metastasis-of-nasopharyngeal-and-cervical-cancer-on-18fdg-pet-ct-a-case-report
#12
Sungmin Kang
Axillary lymph node metastasis (ALNM) from cancer except breast cancer is rare. Whole body 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) that simultaneously offers anatomic and metabolic information is widely used and has become an effective modality in many clinical fields, especially oncology, and also may detect an unexpected metastasis. We report two cases of ALMN of nasopharyngeal and cervical cancer that was detected on whole body PET/CT.
2016: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/27847118/cap-inflammation-leads-to-higher-plaque-cap-strain-and-lower-cap-stress-an-mri-pet-ct-based-fsi-modeling-approach
#13
Dalin Tang, Chun Yang, Sarayu Huang, Venkatesh Mani, Jie Zheng, Pamela K Woodard, Philip Robson, Zhongzhao Teng, Marc Dweck, Zahi A Fayad
Plaque rupture may be triggered by extreme stress/strain conditions. Inflammation is also implicated and can be imaged using novel imaging techniques. The impact of cap inflammation on plaque stress/strain and flow shear stress were investigated. A patient-specific MRI-PET/CT-based modeling approach was used to develop 3D fluid-structure interaction models and investigate the impact of inflammation on plaque stress/strain conditions for better plaque assessment. 18FDG-PET/CT and MRI data were acquired from 4 male patients (average age: 66) to assess plaque characteristics and inflammation...
January 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27832654/predictive-and-prognostic-value-of-early-disease-progression-by-pet-evaluation-in-advanced-non-small-cell-lung-cancer
#14
Giuseppe Luigi Banna, Giuseppe Anile, Giorgio Russo, Paolo Vigneri, Marine Castaing, Maurizio Nicolosi, Salvatore Strano, Stefania Gieri, Rosaria Spina, Domenico Patanè, Giacomo Calcara, Filippo Fraggetta, Francesco Marletta, Alessandro Stefano, Massimo Ippolito
OBJECTIVE: To assess the predictive and prognostic value of progressive metabolic disease (PMD) by the use of early 18Fluorodeoxyglucose positron emission tomography (18FDG-PET) in patients with clinical stage IV non-small cell lung cancer (NSCLC) treated with first-line chemotherapy. METHODS: An 18FDG-PET performed following the first cycle of chemotherapy (PET-1) was compared with a pretreatment 18FDG-PET (PET-0) and a computed tomography (CT) scan after the third cycle (CT-3)...
2017: Oncology
https://www.readbyqxmd.com/read/27814341/association-between-microrna-125a-rs12976445-c-t-polymorphism-and-18f-fluorodeoxyglucose-18fdg-uptake-clinical-and-metabolic-response-in-patients-with-non-small-cell-lung-cancer
#15
Zhina Zang, Wenhua Guan, Diansen Chen, Yan Han, Zhan Shi, Jinjin Zhou
BACKGROUND MicroRNA-125a (miR-125a) has been involved with many diseases, such as hepatocellular carcinoma and inflammation. In this study, we aimed to investigate the molecular mechanism, including the potential regulator and signaling pathways, of vascular endothelial growth factor (VEGF). MATERIAL AND METHODS We divided the participants into 3 groups by rs12976445 genotype and performed chi-square tests to evaluate the differences between CC and CT+TT groups for sex, age, grading, pT category, metastases, and fludeoxyglucose F18 injection (18FDG) metabolism...
November 4, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27796544/the-intensity-of-18fdg-uptake-does-not-predict-tumor-growth-in-patients-with-metastatic-differentiated-thyroid-cancer
#16
Marie Terroir, Isabelle Borget, François Bidault, Marcel Ricard, Frédéric Deschamps, Dana Hartl, Lambros Tselikas, Laurent Dercle, Jean Lumbroso, Eric Baudin, Amandine Berdelou, Désirée Deandreis, Martin Schlumberger, Sophie Leboulleux
PURPOSE: In patients with metastatic differentiated thyroid carcinoma (DTC), fluorodeoxyglucose (FDG) uptake as well as age, tumor size and radioactive iodine (RAI) uptake are prognostic factors for survival. High FDG uptake is a poor prognostic factor and lesions with high FDG uptake are often considered aggressive, but the predictive value of FDG uptake for morphological progression is unknown. The principal aim of this retrospective single center study was to determine whether the intensity of FDG uptake was correlated on a per lesion analysis with tumor growth rate (TGR) expressed as the percentage of increase in tumor size during 1 year (1-year TGR)...
April 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27732127/optimal-gross-tumor-volume-definition-in-lung-sparing-intensity-modulated-radiotherapy-for-pleural-mesothelioma-an-in-silico-study
#17
Angela Botticella, Gilles Defraene, Kristiaan Nackaerts, Christophe M Deroose, Johan Coolen, Philippe Nafteux, Stephanie Peeters, Umberto Ricardi, Dirk De Ruysscher
BACKGROUND: The gross tumor volume (GTV) definition for malignant pleural mesothelioma (MPM) is ill-defined. We therefore investigated which imaging modality is optimal: computed tomography (CT) with intravenous contrast (IVC), positron emission tomography-CT (PET/CT) or magnetic resonance imaging (MRI). MATERIAL AND METHODS: Sixteen consecutive patients with untreated stage I-IV MPM were included. Patients with prior pleurodesis were excluded. CT with IVC, 18FDG-PET/CT and MRI (T2 and contrast-enhanced T1) were obtained...
December 2016: Acta Oncologica
https://www.readbyqxmd.com/read/27716240/salvage-surgery-for-local-failures-after-stereotactic-ablative-radiotherapy-for-early-stage-non-small-cell-lung-cancer
#18
Naomi E Verstegen, Alexander P W M Maat, Frank J Lagerwaard, Marinus A Paul, Michel I Versteegh, Joris J Joosten, Willem Lastdrager, Egbert F Smit, Ben J Slotman, Joost J M E Nuyttens, Suresh Senan
INTRODUCTION: The literature on surgical salvage, i.e. lung resections in patients who develop a local recurrence following stereotactic ablative radiotherapy (SABR), is limited. We describe our experience with salvage surgery in nine patients who developed a local recurrence following SABR for early stage non-small cell lung cancer (NSCLC). METHODS: Patients who underwent surgical salvage for a local recurrence following SABR for NSCLC were identified from two Dutch institutional databases...
October 3, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27688726/primary-mediastinal-b-cell-lymphoma-metabolic-and-anatomical-features-in-18fdg-pet-ct-and-response-to-therapy
#19
Anna Kocurek, Bogdan Małkowski, Agnieszka Giza, Wojciech Jurczak
AIM OF THE STUDY: Determining the role of PET/CT imaging in the evaluation of treatment efficacy in primary mediastinal B-cell lymphoma (PMBCL). MATERIAL AND METHODS: Retrospective analysis of seven PMBCL patients, treated at the University Hospital in Krakow, with interim PET/CT after the third course of chemo-immunotherapy.The analysis was based on the calculation of exact tumour volume and metabolic activity, compared with initial values (directly after diagnosis)...
2016: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/27619910/18fdg-pet-ct-a-useful-tool-for-the-management-of-patients-in-infectious-diseases
#20
Maud Pichon, Nidaa Mikail, Khadija Ben Ali, François Rouzet, Charles Burdet, Yazdan Yazdanpanah, Veronique Joly, Laurent Lepage, Laure Sarda-Mantel
No abstract text is available yet for this article.
February 2017: Infectious Diseases
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