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https://www.readbyqxmd.com/read/27882164/inflammatory-bowel-disease-in-chinese-children-a-retrospective-analysis-of-49-cases
#1
Ying Zhou, Ying Huang
To present study reports the clinical characteristics, diagnosis and management of pediatric patients with inflammatory bowel disease (IBD) in China. Clinical records of 49 pediatric patients with IBD at Fudan University Children's Hospital (Shanghai, China) between July 2001 and May 2012 were reviewed. Of 49 patients (30 males and 19 females), 8 patients had ulcerative colitis (UC) and 41 patients had Crohn's disease (CD). The mean age was 10.4 years in patients with UC and 10.1 years in patients with CD. The percentages of patients with UC with abdominal pain, diarrhea or rectal bleeding were 62...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27843572/utility-of-high-resolution-anorectal-manometry-and-wireless-motility-capsule-in-the-evaluation-of-patients-with-parkinson-s-disease-and-chronic-constipation
#2
Andrew Su, Rita Gandhy, Carrolee Barlow, George Triadafilopoulos
BACKGROUND: The aetiology of constipation in Parkinson's disease remains poorly understood. Defaecatory dyssynergia, anal sphincter spasticity and slow transit constipation may, individually or collectively, play a role. AIMS: In this retrospective cohort analysis of patients with Parkinson's disease and chronic constipation, we determined the utility of high-resolution anorectal manometry, balloon expulsion and wireless motility capsule testing in defining the underlying aetiology for constipation...
2016: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/27836884/should-rectal-cancer-located-10-15cm-from-the-anal-verge-be-defined-as-colon-cancer
#3
M Swets, A J Breugom, H Gelderblom, C J H van de Velde
No abstract text is available yet for this article.
November 10, 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/27824643/clinical-psychological-and-physiological-correlates-of-patients-who-defecate-after-meal
#4
Michel Bouchoucha, Ghislain Devroede, Florence Mary, Cyriaque Bon, Gheorges Airinei, Bakhtiar Bejou, Robert Benamouzig
BACKGROUND AND AIMS: Food is the most important synchronizer of gastrointestinal motility and secretion. Many patients with functional bowel or anorectal disorders complain of fecal urge and stool output after eating. PATIENTS AND METHODS: In this prospective observational study, 408 consecutive outpatients with functional bowel and/or anorectal disorders (74% female, 50.2±15.6 years, 24.8±5.0 kg/m²) filled Rome III questionnaires. Depression and anxiety scores, a physiological evaluation (total and segmental colonic transit time, colonic transit response to eating using a standard 1000 kcal test meal, and anorectal manometry), were measured...
November 7, 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27824253/a-comparative-pre-phase-i-study-of-the-impact-of-gel-vehicle-volume-on-distal-colon-distribution-user-experience-and-acceptability
#5
Ethel D Weld, Hiwot Hiruy, Kate Morrow Guthrie, Joseph L Fava, Sara Vargas, Karen W Buckheit, Robert W Buckheit, Hans Spiegel, Jennifer C Breakey, Edward J Fuchs, Craig W Hendrix
For persons at risk of HIV infection who practice receptive anal intercourse (RAI), topical rectal microbicides represent a promising option for coitally-dependent protection. The study compared colorectal distribution and user sensory experiences of two different volumes of rectal gel for suitability as rectal microbicide. Eight HIV negative men with a history of recent RAI were enrolled into a two-period, sequence randomized, dosing study comparing 3.5 mL and 10 mL of radiolabeled (1 mCi 99mTc-DTPA) universal placebo hydroxyethyl cellulose (HEC) gel...
November 8, 2016: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/27813487/-quality-of-life-after-colectomy-due-to-ulcerative-colitis
#6
Katrin Gudlaugsdottir, Elsa B Valsdottir, Tryggvi B Stefansson
INTRODUCTION: A significant proportion of patients with ulcerative colitis (UC) undergo colectomy. The aim was to assess the quality of life (QOL) of these patients. MATERIAL AND METHODS: All patients with UC who underwent colectomy at The National University Hospital of Iceland or Akureyri Hospital 1995-2009 were included. 106 patients received three questionnaires. SF-36v2 and EORTC are standardised QOL-questionnaires. The third contained functional questions designed by the researchers...
November 2016: Læknablađiđ
https://www.readbyqxmd.com/read/27811832/laparoscopic-assisted-altemeier-s-procedure-for-recurrent-strangulated-rectal-prolapse-a-case-report
#7
Wael M Al-Ameen, Antonio Privitera, Amal Al-Ayed, Khalid Sabr
BACKGROUND Rectal prolapse is an uncommon disease that usually requires surgical intervention. Several techniques have been described with either an abdominal or perineal approach, the latter having a higher recurrence rate. In case of irreducible and strangulated full-thickness prolapse, a perineal approach is necessary, and efforts should be made to reduce recurrence rates. CASE REPORT A 39-year-old mentally retarded woman presented with a painful, recurrent, strangulated sigmoid prolapse following a perineal recto-sigmoidectomy (Altemeier's procedure) for strangulated rectal prolapse 2 months previously...
November 4, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27780281/surgical-management-of-functional-constipation-preliminary-report-of-a-new-approach-using-a-laparoscopic-sigmoid-resection-combined-with-a-malone-appendicostomy
#8
Alessandra Gasior, Giulia Brisighelli, Karen Diefenbach, Victoria Alison Lane, Carlos Reck, Richard J Wood, Marc Levitt
Introduction Functional constipation is a common problem in children. It usually can be managed with laxatives but a small subset of patients develop intolerable cramps and need to be temporarily treated with enemas. The senior author has previously reported: 1) open sigmoid resection as a surgical option, but this did not sufficiently reduce the laxative need, then 2) a transanal approach (with resection of rectosigmoid), but this led to a high rate of soiling due to extensive stretching of the anal canal and loss of the rectal reservoir...
October 25, 2016: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27631776/to-drain-or-not-to-drain-infraperitoneal-anastomosis-after-rectal-excision-for-cancer-the-greccar-5-randomized-trial
#9
Quentin Denost, Philippe Rouanet, Jean-Luc Faucheron, Yves Panis, Bernard Meunier, Eddy Cotte, Guillaume Meurette, Sylvain Kirzin, Charles Sabbagh, Jèrôme Loriau, Stèphane Benoist, Christophe Mariette, Igor Sielezneff, Bernard Lelong, François Mauvais, Benoit Romain, Marie-Line Barussaud, Christine Germain, Marie-Quitterie Picat, Eric Rullier, Christophe Laurent
OBJECTIVE: To assess the effect of pelvic drainage after rectal surgery for cancer. BACKGROUND: Pelvic sepsis is one of the major complications after rectal excision for rectal cancer. Although many studies have confirmed infectiveness of drainage after colectomy, there is still a controversy after rectal surgery. METHODS: This multicenter randomized trial with 2 parallel arms (drain vs no drain) was performed between 2011 and 2014. Primary endpoint was postoperative pelvic sepsis within 30 postoperative days, including anastomotic leakage, pelvic abscess, and peritonitis...
September 14, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27631305/colonic-prolapse-after-intersphincteric-resection-for-very-low-rectal-cancer-a-report-of-12-cases
#10
A Chau, M Frasson, C Debove, L Maggiori, Y Panis
BACKGROUND: There are no published data concerning management of patients with exteriorized colonic prolapse (CP) after intersphincteric rectal resection (ISR) and side-to-end coloanal manual anastomosis (CAA) for very low rectal cancer. The aim of the present study was to report our experience in 12 consecutive cases of CP following ISR with CAA. METHODS: From 2006 to 2014, all patients with very low rectal cancer who developed CP after ISR and CAA were reviewed...
October 2016: Techniques in Coloproctology
https://www.readbyqxmd.com/read/27629565/selection-process-can-improve-the-outcome-in-locally-advanced-and-recurrent-colorectal-cancer-activity-and-results-of-a-dedicated-multidisciplinary-colorectal-cancer-centre
#11
Christos Kontovounisios, Emile Tan, Nikhil Pawa, Gina Brown, Diana Tait, David Cunningham, Shahnawaz Rasheed, Paris Tekkis
AIM: There is wide disparity in the care of patients with multi-visceral involvement of rectal cancer. The results of treatment of advanced and recurrent colorectal cancer are presented from a centre where a dedicated Multidisciplinary Team (MDT) is central to the management. METHOD: All consecutive MDT referrals between 2010 and 2014 were examined. Analysis was undertaken of the referral pathway, site, selection process, management decision, R0 resection rate, mortality / morbidity / Clavien-Dindo (CD) classification of morbidity, length of stay (LOS), and improvement of quality of life...
September 15, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27585438/severe-fournier-s-gangrene-in-a-patient-with-rectal-cancer-case-report-and-literature-review
#12
Yu Yoshino, Kimihiko Funahashi, Rei Okada, Yasuyuki Miura, Takayuki Suzuki, Takamaru Koda, Kimihiko Yoshida, Junichi Koike, Hiroyuki Shiokawa, Mitsunori Ushigome, Tomoaki Kaneko, Yasuo Nagashima, Mayu Goto, Akiharu Kurihara, Hironori Kaneko
BACKGROUND: Fournier's gangrene in the setting of rectal cancer is rare. Treatment for Fournier's gangrene associated with rectal cancer is more complex than other cases of Fournier's gangrene. We report on a patient with severe Fournier's gangrene in the setting of locally advanced rectal cancer who was treated with a combined modality therapy. CASE PRESENTATION: A 65-year-old man presented with general fatigue and anal pain. The medical and surgical histories were unremarkable...
September 1, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27477670/rectal-prolapse-in-winnie-mice-with-spontaneous-chronic-colitis-changes-in-intrinsic-and-extrinsic-innervation-of-the-rectum
#13
Ahmed A Rahman, Ainsley M Robinson, Simon J H Brookes, Rajaraman Eri, Kulmira Nurgali
Rectal prolapse is associated with diminished anal sensitivity and rectal motor activity. Both sensory and motor functions are controlled by the extrinsic and intrinsic (enteric nervous system) innervation of the gastrointestinal tract. Studies of changes in intestinal innervation in humans and in animal models with rectal prolapse are extremely scarce. The Winnie mouse model of spontaneous chronic colitis closely represents human inflammatory bowel disease and is prone to develop rectal prolapse. We have investigated changes in the myenteric and inhibitory motor neurons and evaluated changes in the density of sensory afferent, sympathetic, and parasympathetic fibers in the rectal colon of Winnie mice with and without rectal prolapse...
August 1, 2016: Cell and Tissue Research
https://www.readbyqxmd.com/read/27476229/subserosal-sigmoid-lipoma-a-case-report-and-review-of-the-literature
#14
REVIEW
Daniel Zemenfes, Zelalem Semegnew
Colonic lipoma is a rare non-epithelial mesenchymal tumour which is the second most common benign tumour of the colon excluding hyper-plastic polyps. It is often small and asymptomatic but may become symptomatic and mimic malignant lesions as the size increases. This is a case report of a 68 year-old female patient who presented with lower abdominal pain, constipation and rectal bleeding of one year duration. Colonoscopy revealed a sessile tumour 40 cm from the anal verge with an inconclusive histology. After incising and removing the lipoma, the redundant mucosal fold was then resected...
April 2016: Ethiopian Medical Journal
https://www.readbyqxmd.com/read/27475305/regular-aspirin-use-associates-with-lower-risk-of-colorectal-cancers-with-low-numbers-of-tumor-infiltrating-lymphocytes
#15
Yin Cao, Reiko Nishihara, Zhi Rong Qian, Mingyang Song, Kosuke Mima, Kentaro Inamura, Jonathan A Nowak, David A Drew, Paul Lochhead, Katsuhiko Nosho, Teppei Morikawa, Xuehong Zhang, Kana Wu, Molin Wang, Wendy S Garrett, Edward L Giovannucci, Charles S Fuchs, Andrew T Chan, Shuji Ogino
BACKGROUND & AIMS: Aspirin use reduces colorectal cancer risk. Aspirin, a nonsteroidal anti-inflammatory drug, inhibits prostaglandin-endoperoxide synthase 2 (PTGS2 or cyclooxygenase-2); PTGS2 promotes inflammation and suppresses T-cell-mediated adaptive immunity. We investigated whether the inverse association of aspirin use with colorectal carcinoma risk was stronger for tumors with lower degrees of lymphocytic infiltrates than for tumors with higher degrees of lymphocytic infiltrates...
July 27, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27467330/-the-effect-of-oxygen-on-endotoxin-production-in-bacteria-of-the-bacteroides-fragilis-group-isolated-from-patients-with-colorectal-carcinoma
#16
D Chmelař, M Hájek, J Janečková, J Vobejdová, P Martineková, A Kašíková
OBJECTIVE: The aim of the study was to draw attention to the risk posed by anaerobic bacteria of the Bacteroides fragilis (BAFR) group, isolated particularly from abdominal lesions, and to assess the possible role of these species in colorectal cancer. A correlation has previously been suggested between the detection of the bacteria of the genus Bacteroides in patients on a meat-based diet and intestinal and, in particular, colorectal cancer. Given that the species of the BAFR group are major producers of endotoxins, measurements and statistical analysis of endotoxin production were used to compare the Bacteroides strains isolated from clinical specimens of patients with colon cancer, rectal cancer, and other abdominal lesions...
2016: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/27458493/laparoscopic-and-natural-orifice-transluminal-restorative-proctocolectomy-no-abdominal-incision-for-specimen-extraction-or-ileostomy
#17
Cuneyt Kayaalp, Mehmet Ali Yagci, Vural Soyer
The aim of this study was to demonstrate the feasibility of laparoscopic restorative proctocolectomy (LRPC) without additional abdominal incisions. Two sisters with familial adenomatous polyposis were enrolled. The colon and rectum were mobilized entirely through the five abdominal trocars. The terminal ileum and distal rectum were transected with endoscopic staplers. The entire colorectal specimen was extracted transanally. A circular stapler anvil was introduced transanally. The J-pouch was created intracorporeally...
2016: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/27456545/two-stage-laparoscopic-curative-resection-for-synchronous-multiple-colorectal-cancers-a-case-report
#18
Rina Takahashi, Kazuhiro Sakamoto, Yuichi Tomiki, Yutaka Kojima, Makoto Takahashi, Kiichi Sugimoto, Masaya Kawai, Yu Okazawa, Yurika Makino
A 75-year-old man tested positive for occult blood in the stool. A subsequent examination indicated concurrent locally advanced cancer (cT3) at the hepatic flexure and lower rectum cancer in the external anal sphincter. Because of the locally advanced rectal cancer (cT4), preoperative chemoradiotherapy was administered. First, laparoscopic right hemicolectomy and colostomy were performed at the sigmoid colon. Chemoradiotherapy for rectal cancer was initiated on day 18 after the surgeries. Seven weeks after chemoradiotherapy had been completed, laparoscopic abdominoperineal resection and right lateral pelvic lymph node dissection were performed...
July 26, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27434944/-substantiation-of-formation-and-results-of-application-of-a-new-kind-of-pelvic-small-intestinal-anatomic-functional-the-reservoire-type-construction-after-performance-of-colectomy-extremely-low-rectal-resection-and-mucosectomy-part-1
#19
A I Poyda, V M Melnik
For prophylaxis of severe signs of the postcolectomy and diarrheal syndromes, as well as the secondary anal incontinence syndrome, occurring after extended radical operation--colectomy, extremely low anterior rectal resection, mucosectomy, performed for severe diffuse nontumoral colon diseases, a pelvic small-intestinal anatomic-functional reservoir construction of a new type, which includes a small-intestinal reservoir with ileoendoanal anastomosis, was elaborated. In accordance to data on roentgenological control of the contrast small-intestinal transit the laws of its abdominal localization and peculiarities of morphological reconstruction in late terms after the operation were established...
April 2016: Klinichna Khirurhiia
https://www.readbyqxmd.com/read/27353095/-advances-of-minimally-invasive-technique-in-colorectal-cancer-surgery
#20
Xishan Wang
Colorectal surgery is rapidly developing in the direction of minimally invasive surgery and functional surgery. New technology and ideas are constantly emerging recently. Laparoscopic colon surgery has already been recommended by NCCN guideline. However, laparoscopic rectal cancer surgery still needs to wait for survival and recurrence rates of long-term follow-up data for verification. In recent years, with the rapid progression of imaging equipment of laparoscope, the new 3D laparoscopic system will process image more quickly, and surgeons can get space depth feeling like open surgery only with a pair of glasses...
June 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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