Wei Hu, Zhi Yong Zhai, Zhao Yu Huang, Ze Min Chen, Ping Zhou, Xia Xi Li, Gen Hua Yang, Chong Ju Bao, Li Juan You, Xiao Bing Cui, Gui Li Xia, Mei Ping Ou Yang, Lin Zhang, William Ka Kei Wu, Long Fei Li, Yu Xuan Zhang, Zhan Gang Xiao, Wei Gong
UNLABELLED: Helicobacter pylori is a highly successful pathogen that poses a substantial threat to human health. However, the dynamic interaction between H. pylori and the human gastric epithelium has not been fully investigated. In this study, using dual RNA sequencing technology, we characterized a cytotoxin-associated gene A ( cagA )-modulated bacterial adaption strategy by enhancing the expression of ATP-binding cassette transporter-related genes, metQ and HP_0888 , upon coculturing with human gastric epithelial cells...
March 22, 2024: MSystems