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https://www.readbyqxmd.com/read/29793128/convolutional-neural-networks-for-seizure-prediction-using-intracranial-and-scalp-electroencephalogram
#1
Nhan Duy Truong, Anh Duy Nguyen, Levin Kuhlmann, Mohammad Reza Bonyadi, Jiawei Yang, Samuel Ippolito, Omid Kavehei
Seizure prediction has attracted growing attention as one of the most challenging predictive data analysis efforts to improve the life of patients with drug-resistant epilepsy and tonic seizures. Many outstanding studies have reported great results in providing sensible indirect (warning systems) or direct (interactive neural stimulation) control over refractory seizures, some of which achieved high performance. However, to achieve high sensitivity and a low false prediction rate, many of these studies relied on handcraft feature extraction and/or tailored feature extraction, which is performed for each patient independently...
May 7, 2018: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29793126/effect-of-manual-therapy-versus-proprioceptive-neuromuscular-facilitation-in-dynamic-balance-mobility-and-flexibility-in-field-hockey-players-a-randomized-controlled-trial
#2
Gemma V Espí-López, Susana López-Martínez, Marta Inglés, Pilar Serra-Añó, Marta Aguilar-Rodríguez
OBJECTIVES: To compare the effectiveness of a specific Manual Therapy (MT) protocol applied to field hockey players (FHP), versus a Proprioceptive Neuromuscular Facilitation (PNF) protocol, in the improvement of dynamic balance, active range of movement and lumbar flexibility one-week and four-weeks after the treatment. DESIGN: Randomized controlled trial. Participants were assigned to 2 groups: MT and PNF. 30 min' sessions were performed once a week for three weeks...
April 22, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29793053/aggressive-fluid-and-sodium-restriction-in-decompensated-heart-failure-with-preserved-ejection-fraction-results-from-a-randomized-clinical-trial
#3
Karina Sanches Machado d'Almeida, Eneida Rejane Rabelo-Silva, Gabriela Corrêa Souza, Melina Maria Trojahn, Sofia Louise Santin Barilli, Graziella Aliti, Luís Eduardo Rohde, Andreia Biolo, Luís Beck-da-Silva
OBJECTIVES: Sodium and fluid restriction is commonly prescribed for heart failure patients. However, its role in the treatment of heart failure with preserved ejection fraction (HFpEF) remains unclear. The aim of this study was to compare the effect of a diet with sodium and fluid restriction with an unrestricted diet in patients admitted for decompensated HFpEF. METHODS: Patients were randomized to a diet with sodium (0.8 g/d) and fluid (800 mL/d) restriction (intervention group [IG]) or an unrestricted diet (control group [CG]) and followed for 7 d or hospital discharge...
March 21, 2018: Nutrition
https://www.readbyqxmd.com/read/29793002/rasch-analysis-suggested-that-items-from-the-template-for-intervention-description-and-replication-tidier-checklist-can-be-summed-to-create-a-score
#4
Tie P Yamato, Chris G Maher, Bruno T Saragiotto, Mark J Catley, Anne M Moseley
OBJECTIVE: The aim of this study was to construct and evaluate a summary score of reporting completeness based on the Template for Intervention Description and Replication (TIDieR). STUDY DESIGN AND SETTING: We included 200 reports published in 2013 randomly selected from the Physiotherapy Evidence Database (PEDro). We summed the scores for the 12 items for the intervention and control groups for each trial in order to create a summary score from 0 to 24. Rasch analysis was used to investigate the item hierarchy, category function and reliability of the TIDieR checklist and determine the extent to which the summary score can be considered an interval-level measure...
May 21, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29792940/a-randomized-control-trial-to-determine-the-effectiveness-and-physiological-effects-of-spinal-manipulation-and-spinal-mobilization-compared-to-each-other-and-a-sham-condition-in-patients-with-chronic-low-back-pain-study-protocol-for-the-relief-study
#5
Brian C Clark, David W Russ, Masato Nakazawa, Christopher R France, Stevan Walkowski, Timothy D Law, Megan Applegate, Niladri Mahato, Samuel Lietkam, James Odenthal, Daniel Corcos, Simeon Hain, Betty Sindelar, Robert J Ploutz-Snyder, James S Thomas
BACKGROUND: Low back pain (LBP) is one of the most common reasons for seeking medical care. Manipulative therapies are a common treatment for LBP. Few studies have compared the effectiveness of different types of manipulative therapies. Moreover, the physiologic mechanisms underlying these treatments are not fully understood. Herein, we present the study protocol for The Researching the Effectiveness of Lumbar Interventions for Enhancing Function Study (The RELIEF Study). METHODS AND STUDY DESIGN: The RELIEF Study is a Phase II RCT with a nested mechanistic design...
May 21, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29792935/lp533401-restores-bone-health-in-5-6-nephrectomized-rats-by-a-decrease-of-gut-derived-serotonin-and-regulation-of-serum-phosphate-through-the-inhibition-of-phosphate-co-transporters-expression-in-the-kidneys
#6
Dariusz Pawlak, Beata Znorko, Bartlomiej Kalaska, Tomasz Domaniewski, Radosław Zawadzki, Paweł Lipowicz, Michał Doroszko, Urszula Łebkowska, Piotr Grabowski, Krystyna Pawlak
LP533401 is an orally bioavailable small molecule that inhibits tryptophan hydroxylase-1, an enzyme responsible for the synthesis of gut-derived serotonin (GDS). Recently, we showed that increased GDS in rats with chronic kidney disease (CKD) affected bone strength and metabolism. We tested the hypothesis that treatment with LP533401 could reverse CKD-induced bone loss in uremia. Sixteen weeks after 5/6 nephrectomy, rats were randomized into untreated (CKD), treated with vehicle (VEH) and LP533401 at a dose of 30 or 100 mg/kg daily for 8 weeks...
May 21, 2018: Bone
https://www.readbyqxmd.com/read/29792887/auditory-priming-improves-neural-synchronization-in-auditory-motor-entrainment
#7
Jewel E Crasta, Michael H Thaut, Charles W Anderson, Patricia L Davies, William J Gavin
Neurophysiological research has shown that auditory and motor systems interact during movement to rhythmic auditory stimuli through a process called entrainment. This study explores the neural oscillations underlying auditory-motor entrainment using electroencephalography. Forty young adults were randomly assigned to one of two control conditions, an auditory-only condition or a motor-only condition, prior to a rhythmic auditory-motor synchronization condition (referred to as combined condition). Participants assigned to the auditory-only condition (auditory-first group) listened to 400 trials of auditory stimuli presented every 800ms, while those in the motor-only condition (motor-first group) were asked to tap rhythmically every 800ms without any external stimuli...
May 21, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/29792885/effects-of-vasopressin-on-neural-processing-of-infant-crying-in-expectant-fathers
#8
Sandra Thijssen, Anna E Van 't Veer, Jurriaan Witteman, Willemijn M Meijer, Marinus H van IJzendoorn, Marian J Bakermans-Kranenburg
In a randomized, double blind, placebo-controlled, within-subject magnetic resonance imaging study, we examined the effect of 20 IU intranasal vasopressin on the neural processing of infant crying in 25 fathers-to-be. We explored whether familial background modulates vasopressin effects, and whether vasopressin differentially affects cry processing coupled with neutral or emotional contextual information. Participants listened to cries accompanied by neutral ('this is an infant') or emotional ('this infant is sick/bored') contextual information, and neutral control sounds ('this is a saw')...
May 21, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/29792839/patient-choice-of-adjunctive-non-pharmacologic-pain-management-during-first-trimester-abortion-a-randomized-controlled-trial
#9
Mary Tschann, Jennifer Salcedo, Reni Soon, Bliss Kaneshiro
OBJECTIVE: To determine if offering patients a choice of adjunctive non-pharmacologic pain management during first-trimester aspiration abortion results in lower pain scores than seen without offering these additional measures. STUDY DESIGN: We enrolled women receiving first-trimester aspiration abortion at the University of Hawai'i. We randomized patients to standard care (control), or standard care plus a choice of non-pharmacologic pain management options (intervention)...
May 21, 2018: Contraception
https://www.readbyqxmd.com/read/29792756/uterine-or-paracervical-lidocaine-application-for-pain-control-during-intrauterine-contraceptive-device-insertion-a-meta-analysis-of-randomised-controlled-trials
#10
Faustino R Perez-Lopez, Samuel J Martinez-Dominguez, Gonzalo R Perez-Roncero, Adrian V Hernandez
OBJECTIVE: Systematic review and meta-analysis to assess the effects of uterine or paracervical lidocaine application on pain control during IUD insertion. METHODS: PubMed and five other electronic research databases were searched through 15 November 2017 for RCTs comparing lidocaine treatment vs. a control (placebo or no-intervention) to prevent pain during IUD insertion. Searched terms included 'IUD insertion', 'lidocaine' and 'randomised controlled trial'. RCTs evaluating lidocaine treatment before IUD insertion without restriction of language, age and IUD type...
May 24, 2018: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/29792749/engagement-with-a-text-messaging-intervention-improves-adherence-in-adolescents-with-type-1-diabetes-brief-report
#11
Shuodan Zhang, Emily Hamburger, Sachini Kahanda, Morgan Lyttle, Rodayne Williams, Sarah S Jaser
Adherence to diabetes management is a challenge for adolescents with type 1 diabetes (T1D). Positive psychology interventions have improved adherence to treatment recommendations in adults with chronic health conditions but have not been widely tested in pediatric populations. We hypothesized that higher engagement with a text-messaging intervention to promote positive affect would increase the effects on diabetes management among adolescents with T1D. Adolescents with T1D (n = 48) and their caregivers were randomized to either an attention control condition or a novel positive psychology intervention delivered through personalized automated text messaging...
May 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29792597/increasing-plant-diversity-with-border-crops-reduces-insecticide-use-and-increases-crop-yield-in-urban-agriculture
#12
Nian-Feng Wan, You-Ming Cai, Yan-Jun Shen, Xiang-Yun Ji, Xiang-Wen Wu, Xiang-Rong Zheng, Wei Cheng, Jun Li, Yao-Pei Jiang, Xin Chen, Jacob Weiner, Jie-Xian Jiang, Ming Nie, Rui-Ting Ju, Tao Yuan, Jian-Jun Tang, Wei-Dong Tian, Hao Zhang, Bo Li
Urban agriculture is making an increasing contribution to food security in large cities around the world. The potential contribution of biodiversity to ecological intensification in urban agricultural systems has not been investigated. We present monitoring data collected from rice fields in 34 community farms in mega-urban Shanghai, China, from 2001 to 2015, and show that the presence of a border crop of soybeans and neighboring crops (maize, eggplant and Chinese cabbage), both without weed control, increased invertebrate predator abundance, decreased the abundance of pests and dependence on insecticides, and increased grain yield and economic profits...
May 24, 2018: ELife
https://www.readbyqxmd.com/read/29792582/advancing-child-sexual-abuse-prevention-in-schools-an-exploration-of-the-effectiveness-of-the-enough-online-training-program-for-k-12-teachers
#13
Melinda Gushwa, Jetta Bernier, David Robinson
Child sexual abuse (CSA) in schools and educator misconduct represents a threat to the safety and well-being of our children. The Enough! Preventing Child Sexual Abuse in My School program is a 1-hour online training course developed to address the problem of sexual misconduct and CSA in K-12 education via the use of two avatars/teachers who are navigating CSA and misconduct in their schools. One hundred and thirty-four teachers from three school districts participated in a study to examine the effectiveness of the program in terms of knowledge awareness, including prevalence rates, types of CSA behaviors, impact of CSA on children, signs and symptoms, reporting responsibilities and responses to suspected abuse...
May 24, 2018: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29792556/effect-of-wii-training-on-hand-function-in-children-with-hemiplegic-cerebral-palsy
#14
Shamekh Mohamed El-Shamy, Mohamed Fawzy El-Banna
OBJECTIVE: The purpose of this study was to investigate the effect of Wii training on hand function in children with hemiplegic cerebral palsy. METHODS: A randomized controlled trial was conducted in 40 children with hemiplegic cerebral palsy (8-12 years). The experimental group received Wii training involving four games for 40 minutes a day, three times a week for 12 weeks plus usual care. The control group received usual care alone. Outcomes were spasticity measured using the modified Ashworth scale, grip strength measured using dynamometry, and hand function measured using the Peabody developmental motor scale (2nd ed...
May 24, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29792554/effect-of-acetazolamide-and-methazolamide-on-diaphragm-and-dorsiflexor-fatigue-a-randomized-controlled-trial
#15
Paolo B Dominelli, Chris J McNeil, Tyler Dennis Vermeulen, Troy J R Stuckless, Courtney V Brown, Giulio S Dominelli, Erik Richard Swenson, Lucas J Teppema, Glen Edward Foster
Acetazolamide, a carbonic anhydrase (CA) inhibitor used clinically and to prevent acute mountain sickness, worsens skeletal muscle fatigue in animals and humans. In animals, methazolamide, a methylated analogue of acetazolamide and an equally potent CA inhibitor, reportedly exacerbates fatigue less than acetazolamide. Accordingly, we sought to determine, in humans, if methazolamide would attenuate diaphragm and dorsiflexor fatigue compared to acetazolamide. Healthy men (dorsiflexor: n=12; diaphragm: n=7) performed fatiguing exercise on three occasions, after ingesting acetazolamide (250 mg three times a day) and then in random order, methazolamide (100 mg twice a day) or placebo for 48 h...
May 24, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29792544/synergistic-phytochemicals-fail-to-protect-against-ovariectomy-induced-bone-loss-in-rats
#16
Suresh Ambati, Colette N Miller, Erica F Bass, Natalie M Hohos, Diane L Hartzell, Emily W Kelso, Emily R Trunnell, Jeong-Yeh Yang, Mary Anne Della-Fera, Clifton A Baile, Srujana Rayalam
Menopause induces a loss of bone as a result of estrogen deficiency. Despite pharmaceutical options for the treatment of osteopenia and osteoporosis, many aging women use dietary supplements with estrogenic activity to prevent bone loss and other menopausal-related symptoms. Such supplements are yet to be tested for efficacy against a Food and Drug Administration (FDA) approved medication for menopausal bone loss such as zoledronic acid (ZA). The postmenopausal rat model was used to investigate the efficacy of various synergistic phytochemical blends mixed into the diet for 16 weeks...
May 24, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29792533/efficacy-of-the-resilience-and-adjustment-intervention-after-traumatic-brain-injury-a-randomized-controlled-trial
#17
Jeffrey S Kreutzer, Jennifer H Marwitz, Adam P Sima, Ana Mills, Nancy H Hsu, Herman R Lukow
OBJECTIVE: Examine a psychoeducational and skill-building intervention's effectiveness for individuals after traumatic brain injury (TBI), using a two-arm, parallel, randomized, controlled trial with wait-listed control. METHODS: The Resilience and Adjustment Intervention (RAI) targets adjustment challenges and emphasizes education, skill-building and psychological support. Overall, 160 outpatients were randomly assigned to a treatment or wait-list control (WLC) group...
May 24, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29792492/evaluation-of-second-step-on-early-elementary-students-academic-outcomes-a-randomized-controlled-trial
#18
Clayton R Cook, Sabina Low, Joanne Buntain-Ricklefs, Kelly Whitaker, Michael D Pullmann, Jaclyn Lally
Research has consistently linked social-emotional learning to important educational and life outcomes. Early elementary represents an opportune developmental period to proactively support children to acquire social-emotional skills that enable academic success. Using data from a large scale randomized controlled trial, the purpose of this study was to investigate the impact of the 4th edition of Second Step on early elementary students' academic-related outcomes. Participants were Kindergarten to 2nd grade students in 61 schools (310 teachers; 7,419 students) across six school districts in Washington State and Arizona...
May 24, 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29792491/does-oral-language-underpin-the-development-of-later-behavior-problems-a-longitudinal-meta-analysis
#19
Jason C Chow, Erik Ekholm, Heather Coleman
OBJECTIVE: The purpose of this article is to estimate the overall weighted mean effect of the relation between early language skills and later behavior problems in school-aged children. METHOD: A systematic literature search yielded 19,790 unduplicated reports, and a structured search strategy and identification procedure yielded 25 unique data sets, with 114 effect sizes for analysis. Eligible reports were then coded, and effect sizes were extracted and synthesized via robust variance estimation and random-effects meta-analytic techniques...
May 24, 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29792425/roasted-barley-extract-mugi-cha-containing-cyclo-d-phe-l-pro-prevents-lowering-of-cutaneous-blood-flow-and-skin-temperature-under-air-conditioning-a-randomized-double-blind-placebo-controlled-crossover-study
#20
Hiroshi Ashigai, Mai Mizutani, Yoshimasa Taniguchi, Yasuko Matsukura, Keiko Nakashima, Emiko Ikeshima, Hiroaki Yajima
Roasted barley extract (RBE), also known as mugi-cha, is a well-known healthy non-caffeinated beverage and its health functionality has been widely reported. Our previous clinical study showed that RBE affects cutaneous blood flow and skin temperature after cold water immersion, and that cyclo (D-Phe-L-Pro) is responsible for its effect. In this study, we investigated whether cyclo (D-Phe-L-Pro)-containing RBE prevents the decrease in cutaneous blood flow and skin temperature in an excessively air-conditioned room...
May 24, 2018: Journal of Agricultural and Food Chemistry
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