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https://www.readbyqxmd.com/read/27933728/sequential-change-detection-and-monitoring-of-temporal-trends-in-random-effects-meta-analysis
#1
Samson Henry Dogo, Allan Clark, Elena Kulinskaya
Temporal changes in magnitude of effect sizes reported in many areas of research are a threat to the credibility of the results and conclusions of meta-analysis. Numerous sequential methods for meta-analysis have been proposed to detect changes and monitor trends in effect sizes so that meta-analysis can be updated when necessary and interpreted based on the time it was conducted. The difficulties of sequential meta-analysis under the random-effects model are caused by dependencies in increments introduced by the estimation of the heterogeneity parameter τ(2) ...
December 8, 2016: Research Synthesis Methods
https://www.readbyqxmd.com/read/27933720/autogenous-bone-grafting-for-treatment-of-osseous-defect-after-impacted-mandibular-third-molar-extraction-a-randomized-controlled-trial
#2
Jing Ge, Chi Yang, Jiawei Zheng, Yingkai Hu
BACKGROUND: Extraction of impacted mandibular third molar (M3) has been cited as causing osseous defect at the distal aspect of the adjacent second molar (M2). PURPOSE: This randomized controlled trial was aimed to evaluate the effect of autogenous bone grafting in situ for regeneration of periodontal osseous defect distal to the M2 compared with non-grafting after impacted M3 removal. MATERIALS AND METHODS: A total of 60 sites in 51 adult patients were enrolled and randomly assigned to the control group or the test group...
December 8, 2016: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/27933715/efficacy-of-self-monitoring-of-blood-glucose-versus-retrospective-continuous-glucose-monitoring-in-improving-glycaemic-control-in-diabetic-kidney-disease-patients
#3
Ester Chai Kheng Yeoh, Boon Khim Lim, Sharon Fun, Julia Tong, Lee Ying Yeoh, Chee Fang Sum, Tavintharan Subramaniam, Su Chi Lim
AIMS: Patients with diabetic kidney disease (DKD) on anti-diabetic agents, are at greater risk of glycemic variations, both hypoglycemia and hyperglycemia. We aimed to compare glycemic control (using HbA1c) and hypoglycemia incidence in patients with Stage 3 DKD (eGFR 30-60 ml/min/1.73 m(2) ), receiving retrospective CGM-guided anti-diabetic therapy versus self-monitoring of blood glucose (SMBG) over 3 months. METHODS: Thirty patients with HbA1c > 8% were randomized to 6-day retrospective CGM or SMBG...
December 9, 2016: Nephrology
https://www.readbyqxmd.com/read/27933703/effects-of-cpap-therapy-on-visceral-fat-thickness-carotid-intima-media-thickness-and-adipokines-in-patients-with-obstructive-sleep-apnoea
#4
Susanna S S Ng, Eric K H Liu, Ronald C W Ma, Tat-On Chan, Kin-Wang To, Ken K P Chan, Jenny Ngai, Wing-Ho Yip, Fanny W S Ko, Chun-Kwok Wong, David S C Hui
BACKGROUND AND OBJECTIVE: Obstructive sleep apnoea (OSA) is associated with an increased prevalence of metabolic syndrome. This study explores the effects of continuous positive airway pressure (CPAP) for patients with OSA on visceral and mesenteric fat thickness, carotid intima-media thickness (IMT) and adipokines. METHODS: A randomized controlled study was conducted at a teaching hospital on 90 patients newly diagnosed with OSA to receive either therapeutic CPAP or subtherapeutic CPAP for 3 months...
December 9, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27933696/commentary-on-blue-blocking-glasses-as-additive-treatment-for-mania-a-randomized-placebo-controlled-trial
#5
Amílcar Silva-Dos-Santos
No abstract text is available yet for this article.
December 9, 2016: Bipolar Disorders
https://www.readbyqxmd.com/read/27933671/causal-inference-in-obesity-research
#6
REVIEW
P W Franks, N Atabaki-Pasdar
Obesity is a risk factor for a plethora of severe morbidities and premature death. Most supporting evidence comes from observational studies that are prone to chance, bias and confounding. Even data on the protective effects of weight loss from randomized controlled trials will be susceptible to confounding and bias if treatment assignment cannot be masked, which is usually the case with lifestyle and surgical interventions. Thus, whilst obesity is widely considered the major modifiable risk factor for many chronic diseases, its causes and consequences are often difficult to determine...
December 8, 2016: Journal of Internal Medicine
https://www.readbyqxmd.com/read/27933574/-long-term-hrv-analysis-shows-stress-reduction-by-magnesium-intake
#7
Elmar Wienecke, Claudia Nolden
BACKGROUND: Mental pressure and stress represent an ever-increasing socio-political challenge. The heart rate variability (HRV) measurement, which has its origin in the cardiac function diagnosis, gives information on the neurovegetative activity. A low HRV shows an imbalance of the sympathetic and parasympathetic efferents and thus is an indicator of stress. METHOD: A randomized, controlled, two-armed parallel study with 100 participants and a period of 90 days was performed...
December 2016: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/27933562/authors-reply-to-anoop-balachandran-et-al-comment-on-sub-anesthetic-xenon-increases-erythropoietin-levels-in-humans-a-randomized-controlled-trial
#8
EDITORIAL
Christian Stoppe, Julia Ney, Rolf Rossaint, Mark Coburn, Andreas Goetzenich
No abstract text is available yet for this article.
December 9, 2016: Sports Medicine
https://www.readbyqxmd.com/read/27933512/effect-of-chinese-medicine-treatment-based-on-pattern-identification-on-cellular-immunophenotype-of-myelodysplastic-syndrome
#9
Yu Zhang, Li-Li Qian, Jian-Ping Shen, Jun-Fa Chen, Yan-Ting Gao, Jing-Jing Xiang, Bao-Dong Ye, Yu-Hong Zhou
OBJECTIVE: To observe the influence of treatment based on Chinese medicine pattern identification on cellular immunophenotype of the myelodysplastic syndrome (MDS). METHODS: Sixty patients with MDS were randomly and equally assigned to the treatment group and the control group using a randomized digital table. Thirty patients in each group included 3 risk levels (low, moderate and high risks) with each level 10 patients according to the international prognostic scoring system...
December 9, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27933509/effect-of-shuanghu-qinggan-granule-and-yigan-yiqi-jieyu-granule-plus-lamivudine-on-chronic-hepatitis-b-patients-a-randomized-double-blind-placebo-controlled-trial
#10
Yong-An Ye, De-Lu Tian, Jian Jiang, Jun Li, Jian-Jie Chen, Zhi-Hong Li, Wei-Guo Ma, Yi-Ming Zhao, Rong-Bing Wang, Shi-Zhong Yang, Feng-Zhen Shao, Guang Ji, Da-Qiao Zhou, Tie-Jun Liu, Dong-Sheng Cheng, Wei Zhang, Ke-Wei Sun, Yu-Fen Wang, Le-Quan Min, Xiao-Ke Li
OBJECTIVE: To observe the clinical efficacy and safety of Shuanghu Qinggan Granule ( , SQG) plus Yigan Yiqi Jieyu Granule (, YYJG) combined with lamivudine (LAM) on chronic hepatitis B (CHB) patients. METHODS: The study was a multicenter, randomized, double-blinded and parallel controlled trial. A total of 320 patients were randomly allocated into 2 groups equally: 160 patients (treatment group) were given SQG and YYJG combined with LAM; and 160 patients (control group) were given LAM plus Chinese herb placebo, respectively...
December 8, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27933462/what-do-you-need-to-get-male-partners-of-pregnant-women-tested-for-hiv-in-resource-limited-settings-the-baby-shower-cluster-randomized-trial
#11
Echezona E Ezeanolue, Michael C Obiefune, Wei Yang, Chinenye O Ezeanolue, Jennifer Pharr, Alice Osuji, Amaka G Ogidi, Aaron T Hunt, Dina Patel, Gbenga Ogedegbe, John E Ehiri
Male partner involvement has the potential to increase uptake of interventions to prevent mother-to-child transmission of HIV (PMTCT). Finding cultural appropriate strategies to promote male partner involvement in PMTCT programs remains an abiding public health challenge. We assessed whether a congregation-based intervention, the Healthy Beginning Initiative (HBI), would lead to increased uptake of HIV testing among male partners of pregnant women during pregnancy. A cluster-randomized controlled trial of forty churches in Southeastern Nigeria randomly assigned to either the HBI (intervention group; IG) or standard of care referral to a health facility (control group; CG) was conducted...
December 8, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27933439/measurement-of-carotid-pulse-wave-velocity-using-ultrafast-ultrasound-imaging-in-hypertensive-patients
#12
Xiaopeng Li, Jue Jiang, Hong Zhang, Hua Wang, Donggang Han, Qi Zhou, Ya Gao, Shanshan Yu, Yanhua Qi
PURPOSE: The study aimed to assess the utility of ultrafast ultrasound imaging for evaluation of carotid pulse wave velocity (PWV) in newly diagnosed hypertension patients. METHODS: This prospective non-randomized study enrolled 90 hypertensive patients in our hospital from September to December 2013 as a hypertension group. An age- and sex-matched cohort of 50 healthy adults in our hospital from September to December 2013 was also included in the study as a control group...
December 8, 2016: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27933425/ethical-issues-in-using-social-media-to-deliver-an-hiv-prevention-intervention-results-from-the-hope-peru-study
#13
Renee Garett, Luis Menacho, Sean D Young
Social media technologies have become increasingly useful tools for research-based interventions. However, participants and social media users have expressed ethical concerns with these studies, such as risks and benefits of participation, as well as privacy, confidentiality, and informed consent issues. This study was designed to follow up with and assess experiences and perceptions of ethics-related issues among a sample of 211 men who have sex with men who participated in the Harnessing Online Peer Education (HOPE) Peru study, a randomized controlled HIV prevention intervention conducted in Peru...
December 9, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/27933408/twelve-weeks-progressive-resistance-training-combined-with-protein-supplementation-beyond-habitual-intakes-increases-upper-leg-lean-tissue-mass-muscle-strength-and-extended-gait-speed-in-healthy-older-women
#14
Peter Francis, William Mc Cormack, Clodagh Toomey, Catherine Norton, Jean Saunders, Emmet Kerin, Mark Lyons, Philip Jakeman
The age-related decline in functional capability is preceded by a reduction in muscle quality. The purpose of this study was to assess the combined effects of progressive resistance training (PRT) and protein supplementation beyond habitual intakes on upper leg lean tissue mass (LTM), muscle quality and functional capability in healthy 50-70 years women. In a single-blinded, randomized, controlled design, 57 healthy older women (age 61.1 ± 5.1 years, 1.61 ± 0.65 m, 65.3 ± 15.3 kg) consumed 0.33 g/kg body mass of a milk-based protein matrix (PRO) for 12 weeks...
December 8, 2016: Biogerontology
https://www.readbyqxmd.com/read/27933401/improvement-of-abnormal-vaginal-flora-in-ugandan-women-by-self-testing-and-short-use-of-intravaginal-antimicrobials
#15
G Donders, G Bellen, F Donders, J Pinget, I Vandevelde, T Michiels, J Byamughisa
The vaginal composition of African women is more often lactobacillus-deficient compared to that of women from other areas around the world. Lactobacillus-deficient microflora is a known risk factor for serious health problems, such as preterm birth, cervix cancer, and entrapment of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). The aim of this study was to assess the effect of local vaginal antibiotic or antiseptic treatment on abnormal vaginal flora (AVF), aerobic vaginitis (AV), and bacterial vaginosis (BV) among women in rural, semi-urban, and urban areas in Uganda, as compared to placebo...
December 8, 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27933399/implementation-of-clinical-decision-support-in-young-children-with-acute-gastroenteritis-a-randomized-controlled-trial-at-the-emergency-department
#16
Dorien Geurts, Evelien de Vos-Kerkhof, Suzanne Polinder, Ewout Steyerberg, Johan van der Lei, Henriëtte Moll, Rianne Oostenbrink
: Acute gastroenteritis (AGE) is one of the most frequent reasons for young children to visit emergency departments (EDs). We aimed to evaluate (1) feasibility of a nurse-guided clinical decision support system for rehydration treatment in children with AGE and (2) the impact on diagnostics, treatment, and costs compared with usual care by attending physician. A randomized controlled trial was performed in 222 children, aged 1 month to 5 years at the ED of the Erasmus MC-Sophia Children's hospital in The Netherlands ( 2010-2012)...
December 8, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27933351/-modern-modifications-of-uvulopalatopharyngoplasty
#17
T Verse, B A Stuck
Uvulopalatopharyngoplasty (UPPP) was first described in 1964 with regard to surgical treatment of snoring and in 1981 with regard to treatment of obstructive sleep apnea (OSA). The initial surgical techniques for OSA were very invasive, frequently leading to significant morbidity and complications. Wolfgang Pirsig et al. were the first in Germany to recognize that a radical surgical technique increased only the complications, not the efficacy of UPPP. The less invasive surgical technique developed based on these findings is still established in Germany...
December 8, 2016: HNO
https://www.readbyqxmd.com/read/27933348/-acupuncture-in-posttonsillectomy-pain-a%C3%A2-prospective-double-blind-randomized-controlled-trial-german-version
#18
J Dingemann, B Plewig, I Baumann, P K Plinkert, S Sertel
BACKGROUND: Postoperative swallowing pain is one of the most unpleasant after-effects of tonsillectomy. During recent years, the demand for alternatives to drug-based pain therapy has continued to grow, although the topic has received little research attention until now. MATERIALS AND METHODS: A total of 46 patients were randomized into verum acupuncture, control acupuncture, and drug-based treatment groups. All patients received nonsteroidal antirheumatic drugs (NSAIDs)...
December 8, 2016: HNO
https://www.readbyqxmd.com/read/27933297/exhibitionist-eating-who-wins-eating-competitions
#19
Brian Wansink, Kevin M Kniffin
OBJECTIVE: How and why does competition and spectator involvement influence eating behaviors? The primary objective of this article is to explore the nature of competitive eating with the goal of identifying implications for other social situations. DESIGN: Study 1 investigated how many chicken wings were eaten by men and women in a 30-min eating competition when cheering spectators either were or were not present (compared to a control condition). The second study sought to explain Study 1's findings through a survey of 93 students who rated male or female competitive eaters (in randomized order) based on intelligence, attractiveness, health, strength, and how romantic they expected the eaters to be...
2016: Frontiers in Nutrition
https://www.readbyqxmd.com/read/27933283/neonatal-diagnostics-toward-dynamic-growth-charts-of-neuromotor-control
#20
Elizabeth B Torres, Beth Smith, Sejal Mistry, Maria Brincker, Caroline Whyatt
The current rise of neurodevelopmental disorders poses a critical need to detect risk early in order to rapidly intervene. One of the tools pediatricians use to track development is the standard growth chart. The growth charts are somewhat limited in predicting possible neurodevelopmental issues. They rely on linear models and assumptions of normality for physical growth data - obscuring key statistical information about possible neurodevelopmental risk in growth data that actually has accelerated, non-linear rates-of-change and variability encompassing skewed distributions...
2016: Frontiers in Pediatrics
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