Mercedes J Burnside, Dana M Lewis, Hamish R Crocket, Renee A Meier, Jonathan A Williman, Olivia J Sanders, Craig A Jefferies, Ann M Faherty, Ryan G Paul, Claire S Lever, Sarah K J Price, Carla M Frewen, Shirley D Jones, Tim C Gunn, Christina Lampey, Benjamin J Wheeler, Martin I de Bock
BACKGROUND: Open-source automated insulin delivery (AID) systems are used by many patients with type 1 diabetes. Data are needed on the efficacy and safety of an open-source AID system. METHODS: In this multicenter, open-label, randomized, controlled trial, we assigned patients with type 1 diabetes in a 1:1 ratio to use an open-source AID system or a sensor-augmented insulin pump (control). The patients included both children (defined as 7 to 15 years of age) and adults (defined as 16 to 70 years of age)...
September 8, 2022: New England Journal of Medicine