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https://www.readbyqxmd.com/read/28318664/risk-assessment-of-patients-with-clinical-manifestations-of-cardiac-sarcoidosis-with-positron-emission-tomography-and-magnetic-resonance-imaging
#1
Paco E Bravo, Ganesh Raghu, David G Rosenthal, Shana Elman, Bradley J Petek, Laurie A Soine, Jeffrey H Maki, Kelley R Branch, Sofia C Masri, Kristen K Patton, James H Caldwell, Eric V Krieger
BACKGROUND: Prior studies have shown that late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) and fluorodeoxyglucose (FDG) positron emission tomography (PET) confer incremental risk assessment in patients with cardiac sarcoidosis (CS). However, the incremental prognostic value of the combined use of LGE and FDG compared to either test alone has not been investigated, and this is the aim of the present study. METHODS: Retrospective observational study of 56 symptomatic patients with high clinical suspicion for CS who underwent LGE-CMR and FDG-PET and were followed for the occurrence of death and/or malignant ventricular arrhythmias (VA)...
March 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28318537/cardiac-magnetic-resonance-imaging-in-suspected-blunt-cardiac-injury-a-prospective-pilot-cohort-study
#2
Aidan Jc Burrell, David M Kaye, Mark C Fitzgerald, David J Cooper, James L Hare, Benedict T Costello, Andrew J Taylor
INTRODUCTION: The aim of this study was to evaluate the incidence and severity of blunt cardiac injury (BCI) as determined by cardiac magnetic resonance imaging (CMR), and to compare this to currently used diagnostic methods in severely injured patients. MATERIALS AND METHODS: We conducted a prospective, pilot cohort study of 42 major trauma patients from July 2013 to Jan 2015. The cohort underwent CMR within 7 days, enrolling 21 patients with evidence of chest injury and an elevated Troponin I compared to 21 patients without chest injury who acted as controls...
February 27, 2017: Injury
https://www.readbyqxmd.com/read/28317480/novel-insights-into-complex-cardiovascular-pathologies-using-4d-flow-analysis-by-cardiovascular-magnetic-resonance-imaging
#3
Adam James Lewandowski, Betty Raman, Rajarshi Banerjee, Matteo Milanesi
BACKGROUND: It is essential that we are able to assess variations in blood flow in order to fully understand cardiovascular function in disease pathologies and for identification of individuals at long-term risk of cardiovascular disease development. Qualitative and quantitative assessments of blood flow by imaging modalities have been limited, and much of the accurate quantification has relied on invasive measures. METHODS: This review discusses how four-dimensional velocity cardiovascular magnetic resonance (4D flow CMR) offers increasing potential for the non-invasive assessment of blood flow in the heart and major blood vessels such as the aorta...
March 17, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28317398/cardiac-transplantation-towards-a-new-noninvasive-approach-of-cardiac-allograft-rejection
#4
Sophie I Mavrogeni, George Athanasopoulos, Aggeliki Gouziouta, Evangelos Leontiadis, Stamatis Adamopoulos, Genovefa Kolovou
Cardiac allograft rejection (CAR) may occur after transplantation and remains silent, until hemodynamic deterioration takes place. Endomyocardial biopsy (EMB) is applied to early detect CAR. Although, flexible bioptoms have decreased the incidence of lethal complications, EMB remains an invasive procedure carrying risk of tamponade and permanent heart block. Therefore, a new non-invasive approach is needed. Areas covered: AlloMap molecular expression testing and graft-derived cell-free DNA (GcfDNA) test can be used as blood indices of acute and chronic CAR, respectively...
March 20, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28317067/pet-cmr-in-heart-failure-synergistic-or-redundant-imaging
#5
REVIEW
Michael A Quail, Albert J Sinusas
Imaging in heart failure (HF) provides data for diagnosis, prognosis and disease monitoring. Both MRI and nuclear imaging techniques have been successfully used for this purpose in HF. Positron Emission Tomography-Cardiac Magnetic Resonance (PET-CMR) is an example of a new multimodality diagnostic imaging technique with potential applications in HF. The threshold for adopting a new diagnostic tool to clinical practice must necessarily be high, lest they exacerbate costs without improving care. New modalities must demonstrate clinical superiority, or at least equivalence, combined with another important advantage, such as lower cost or improved patient safety...
March 20, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28316282/motion-compensated-cine-cmr-of-the-fetal-heart-using-radial-undersampling-and-compressed-sensing
#6
Christopher W Roy, Mike Seed, John C Kingdom, Christopher K Macgowan
BACKGROUND: To develop and evaluate a reconstruction framework for high resolution time-resolved CMR of the fetal heart in the presence of motion. METHODS: Data were acquired using a golden angle radial trajectory in seven fetal subjects and reconstructed as real-time images to detect fetal movement. Data acquired during through-plane motion were discarded whereas in-plane motion was corrected. A fetal cardiac gating signal was extracted to sort the corrected data by cardiac phase, allowing reconstruction of cine images...
March 20, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28315985/role-of-cardiovascular-magnetic-resonance-in-acute-and-chronic-ischemic-heart-disease
#7
A Baritussio, A Scatteia, C Bucciarelli-Ducci
Cardiovascular magnetic resonance (CMR) is a multi-parametric, multi-planar, non-invasive imaging technique, which allows accurate determination of biventricular function and precise myocardial tissue characterization in a one-stop-shop technique, free from the use of ionizing radiations. Though CMR has been increasingly applied over the last two decades in every-day clinical practice, its widest application has been in the assessment of ischemic cardiomyopathy.
March 18, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28315124/multi-modality-imaging-assessment-of-pericardial-masses
#8
REVIEW
Wunan Zhou, Monvadi Barbara Srichai
PURPOSE OF REVIEW: This review will discuss the application of various imaging modalities including their advantages and disadvantages in the evaluation of the most common pericardial masses with a focus on pericardial cysts, tumors, and hematomas. RECENT FINDINGS: Accurate identification of pericardial masses and assessment of potential hemodynamic compromise is imperative for management. Cardiac imaging plays a central role in tissue characterization as well as evaluation of extension into neighboring structures...
April 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28314659/diagnostic-and-prognostic-value-of-cmr-t1-mapping-in-patients-with-heart-failure-and-preserved-ejection-fraction
#9
Karl-Philipp Rommel, Christian Lücke, Philipp Lurz
Heart failure with preserved ejection fraction (HFpEF) presents a major challenge in modern cardiology. Although this syndrome is of increasing prevalence and is associated with unfavorable outcomes, treatment trials have failed to establish effective therapies. Currently, solutions to this dilemma are being investigated, including categorizing and characterizing patients more diversely to individualize treatment. In this regard, new imaging techniques might provide important information. Diastolic dysfunction is a diagnostic and pathophysiological cornerstone in HFpEF and is believed to be caused by systemic inflammation with the development of interstitial myocardial fibrosis and myocardial stiffening...
March 14, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28303211/real-time-three-dimensional-echocardiography-characterization-of-cardiac-anatomy-and-function-current-clinical-applications-and-literature-review-update
#10
REVIEW
Omar Velasco, Morgan Q Beckett, Aaron W James, Megan N Loehr, Taylor G Lewis, Tahmin Hassan, Rajesh Janardhanan
Our review of real-time three-dimensional echocardiography (RT3DE) discusses the diagnostic utility of RT3DE and provides a comparison with two-dimensional echocardiography (2DE) in clinical cardiology. A Pubmed literature search on RT3DE was performed using the following key words: transthoracic, two-dimensional, three-dimensional, real-time, and left ventricular (LV) function. Articles included perspective clinical studies and meta-analyses in the English language, and focused on the role of RT3DE in human subjects...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28302143/altered-aortic-3d-hemodynamics-and-geometry-in-pediatric-marfan-syndrome-patients
#11
Roel L F van der Palen, Alex J Barker, Emilie Bollache, Julio Garcia, Michael J Rose, Pim van Ooij, Luciana T Young, Arno A W Roest, Michael Markl, Joshua D Robinson, Cynthia K Rigsby
BACKGROUND: Blood flow dynamics make it possible to better understand the development of aortopathy and cardiovascular events in patients with Marfan syndrome (MFS). Aortic 3D blood flow characteristics were investigated in relation to aortic geometry in children and adolescents with MFS. METHODS: Twenty-five MFS patients (age 15.6 ± 4.0 years; 11 females) and 21 healthy controls (age 16.0 ± 2.6 years; 12 females) underwent magnetic resonance angiography and 4D flow CMR for assessment of thoracic aortic size and 3D blood flow velocities...
March 17, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28301000/population-based-study-on-infant-mortality
#12
Jaqueline Costa Lima, Alexandre Marchezoni Mingarelli, Neuber José Segri, Arturo Alejandro Zavala Zavala, Olga Akiko Takano
Although Brazil has reduced social, economic and health indicators disparities in the last decade, intra- and inter-regional differences in child mortality rates (CMR) persist in regions such as the state capital of Mato Grosso. This population-based study aimed to investigate factors associated with child mortality in five cohorts of live births (LB) of mothers living in Cuiabá (MT), Brazil, 2006-2010, through probabilistic linkage in 47,018 LB. We used hierarchical logistic regression analysis. Of the 617 child deaths, 48% occurred in the early neonatal period...
March 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28299606/three-dimensional-speckle-tracking-longitudinal-strain-is-related-to-myocardial-fibrosis-determined-by-late-gadolinium-enhancement
#13
Marco Spartera, Anna Damascelli, Ferenc Mozes, Francesco De Cobelli, Giovanni La Canna
Three-dimensional (3D) speckle tracking echocardiography (STE) is a reliable clinical tool for accurate measurements of left ventricular (LV) volumes and ejection fraction (EF). In this prospective study, we sought to identify an association between 3DSTE longitudinal strain abnormalities and areas of late gadolinium enhancement (LGE). In 50 patients (52 ± 18.5 years old) referred to our hospital for clinically indicated CMR, 3D full-volume trans-thoracic acquisitions on apical views were performed within 1 h of CMR, in order to obtain LV volumes and ejection fraction as well as global and segmental peak systolic longitudinal strain...
March 15, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28292302/impact-of-left-ventricular-outflow-tract-ellipticity-on-the-grading-of-aortic-stenosis-in-patients-with-normal-ejection-fraction
#14
Frédéric Maes, Sophie Pierard, Christophe de Meester, Jamila Boulif, Mihaela Amzulescu, David Vancraeynest, Anne-Catherine Pouleur, Agnès Pasquet, Bernhard Gerber, Jean-Louis Vanoverschelde
BACKGROUND: The pathophysiology of paradoxical low-gradient (LG) severe aortic stenosis (SAS) remains controversial. As low transvalvular flow has been implicated, we sought to investigate the impact of left ventricular outflow tract (LVOT) ellipticity on the estimation of the LV stroke volume, the calculation of the aortic valve area (AVA) by use of the continuity equation and on AS severity grading. METHODS: We studied 190 consecutive patients (mean age: 72 ± 13 years; male: 57%) with SAS (indexed AVA < 0...
March 15, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28292197/sudden-death-risk-stratification-in-non-ischemic-dilated-cardiomyopathy-using-old-and-new-tools-a-clinical-challenge
#15
Antonis S Manolis
Risk stratification for sudden cardiac death in non-ischemic dilated cardiomyopathy (NIDCM) remains a clinical challenge. Areas Covered: Currently, left ventricular ejection fraction (LVEF), severity of heart failure symptoms according to NYHA classification, and morphology and duration of the QRS complex guide device management in these patients with implantation of a cardioverter defibrillator (ICD) and/or cardiac resynchronization therapy (CRT) devices. Recently, the results of a randomized trial stirred some controversy regarding the utility of ICD in NIDCM patients, however, a subsequent meta-analysis confirmed prior findings of the survival-prolonging benefit of device therapy...
March 15, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28289525/cardiovascular-magnetic-resonance-imaging-assessment-of-outcomes-in-acute-myocardial-infarction
#16
REVIEW
Jamal N Khan, Gerry P McCann
Cardiovascular magnetic resonance (CMR) imaging uniquely characterizes myocardial and microvascular injury in acute myocardial infarction (AMI), providing powerful surrogate markers of outcomes. The last 10 years have seen an exponential increase in AMI studies utilizing CMR based endpoints. This article provides a contemporary, comprehensive review of the powerful role of CMR imaging in the assessment of outcomes in AMI. The theory, assessment techniques, chronology, importance in predicting left ventricular function and remodelling, and prognostic value of each CMR surrogate marker is described in detail...
February 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28289524/assessment-of-stable-coronary-artery-disease-by-cardiovascular-magnetic-resonance-imaging-current-and-emerging-techniques
#17
REVIEW
James R J Foley, Sven Plein, John P Greenwood
Coronary artery disease (CAD) is a leading cause of death and disability worldwide. Cardiovascular magnetic resonance (CMR) is established in clinical practice guidelines with a growing evidence base supporting its use to aid the diagnosis and management of patients with suspected or established CAD. CMR is a multi-parametric imaging modality that yields high spatial resolution images that can be acquired in any plane for the assessment of global and regional cardiac function, myocardial perfusion and viability, tissue characterisation and coronary artery anatomy, all within a single study protocol and without exposure to ionising radiation...
February 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28287748/colossal-terahertz-magnetoresistance-at-room-temperature-in-epitaxial-la0-7sr0-3mno3-nanocomposites-and-single-phase-thin-films
#18
J Lloyd-Hughes, Connor Mosley, Samuel Jones, Martin R Lees, Aiping Chen, Quanxi Jia, Eun Mi Choi, Judith L MacManus Driscoll
Colossal magnetoresistance (CMR) is demonstrated at terahertz (THz) frequencies by using terahertz time-domain magnetospectroscopy to examine nanocolumns and planar thin films of La0.7Sr0.3MnO3. At the metal-insulator transition the THz conductivity of the nanocolumn film was dramatically enhanced by the application of a magnetic field, creating a non-Drude conductivity that increased with frequency. The colossal magnetoresistance at 1.0THz is -99.9% at the Curie temperature (room temperature), far exceeding the dc magnetoresistance...
March 13, 2017: Nano Letters
https://www.readbyqxmd.com/read/28285594/defining-left-ventricular-remodeling-following-acute-st-segment-elevation-myocardial-infarction-using-cardiovascular-magnetic-resonance
#19
Heerajnarain Bulluck, Yun Yun Go, Gabriele Crimi, Andrew J Ludman, Stefania Rosmini, Amna Abdel-Gadir, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Silvia Pica, Claudia Raineri, Alex Sirker, Anna S Herrey, Charlotte Manisty, Ashley Groves, James C Moon, Derek J Hausenloy
BACKGROUND: The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for assessing LV remodeling following acute MI. METHODS: Firstly, 40 reperfused ST-segment elevation myocardial infarction (STEMI) patients with paired acute (4 ± 2 days) and follow-up (5 ± 2 months) CMR scans were analyzed by 2 independent reviewers and the minimal detectable changes (MDCs) for percentage change in LV end-diastolic volume (%ΔLVEDV), LV end-systolic volume (%ΔLVESV), and LV ejection fraction (%ΔLVEF) between the acute and follow-up scans were determined...
March 13, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28285066/comprehensive-medication-review-recipients-opinions-actions-and-information-recall
#20
Nick Schulte, Janelle F Ruisinger, Emily S Prohaska, Katelyn M Steele, Brittany L Melton
OBJECTIVES: Assess patients' and caregivers' perceptions of comprehensive medication review (CMR) offers and when a CMR is needed, follow-up actions performed after the CMR, and recall of pharmacists' recommendations made during CMRs. METHODS: A 22-item cross-sectional survey with multiple response, 5-point Likert scale (1 = strongly disagree; 5 = strongly agree), yes/no, and free response prompts was administered to patients and caregivers who completed a CMR between October 1, 2014, and September 30, 2015...
March 8, 2017: Journal of the American Pharmacists Association: JAPhA
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