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https://www.readbyqxmd.com/read/29762792/medical-student-interest-in-flexible-residency-training-options
#1
Madison Piotrowski, Debra Stulberg, Mari Egan
BACKGROUND AND OBJECTIVES: Medical residents continue to experience high rates of burnout during residency training even after implementation of the 2003 Accreditation Council for Graduate Medical Education duty-hour restrictions. The purpose of this study is to determine medical student interest in flexible residency training options. METHODS: Researchers developed an 11-question survey for second through fourth-year medical students. The populations surveyed included medical students who were: (1) attending the 2015 American Academy of Family Physicians National Conference, the 2015 Family Medicine Midwest Conference, and (2) enrolled at University of Chicago Pritzker School of Medicine, University of Illinois College of Medicine at Chicago, Drexel University College of Medicine, and Case Western Reserve University School of Medicine...
May 2018: Family Medicine
https://www.readbyqxmd.com/read/29685638/a-human-centered-approach-to-cv-care-infrastructure-development-in-uganda
#2
Christopher T Longenecker, Ankur Kalra, Emmy Okello, Peter Lwabi, John O Omagino, Cissy Kityo, Moses R Kamya, Allison R Webel, Daniel I Simon, Robert A Salata, Marco A Costa
In this case study, we describe an ongoing approach to develop sustainable acute and chronic cardiovascular care infrastructure in Uganda that involves patient and provider participation. Leveraging strong infrastructure for HIV/AIDS care delivery, University Hospitals Harrington Heart and Vascular Institute and Case Western Reserve University have partnered with U.S. and Ugandan collaborators to improve cardiovascular capabilities. The collaboration has solicited innovative solutions from patients and providers focusing on education and advanced training, penicillin supply, diagnostic strategy (e...
April 20, 2018: Global Heart
https://www.readbyqxmd.com/read/29642459/bearing-fault-diagnosis-by-a-robust-higher-order-super-twisting-sliding-mode-observer
#3
Farzin Piltan, Jong-Myon Kim
An effective bearing fault detection and diagnosis (FDD) model is important for ensuring the normal and safe operation of machines. This paper presents a reliable model-reference observer technique for FDD based on modeling of a bearing's vibration data by analyzing the dynamic properties of the bearing and a higher-order super-twisting sliding mode observation (HOSTSMO) technique for making diagnostic decisions using these data models. The HOSTSMO technique can adaptively improve the performance of estimating nonlinear failures in rolling element bearings (REBs) over a linear approach by modeling 5 degrees of freedom under normal and faulty conditions...
April 7, 2018: Sensors
https://www.readbyqxmd.com/read/29557838/developing-a-problem-based-learning-approach-to-the-integration-of-environmental-and-occupational-health-topics-into-medical-school-curriculum
#4
Anisha Garg, Karen B Mulloy
OBJECTIVES: Pilot study incorporating environmental and occupational health (EOH) learning objectives into medical school curriculum using problem based learning approach. METHODS: 184 Case Western Reserve University medical students participated in problem based learning curriculum emphasizing EOH topics. Multiple choice (MCQ), short essay (SEQ), and summative short essay (SSEQ) questions assessed student knowledge. Two rating scale questions and one open-ended question determined student attitudes and confidence...
March 19, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29408298/from-hypothermia-to-cephalosomatic-anastomoses-the-legacy-of-robert-white-1926-2010-at-case-western-reserve-university-of-cleveland
#5
REVIEW
Sunil Manjila, Vilakshan Alambyan, Gagandeep Singh, Priyanka Satish, Robert T Geertman
Dr. Robert J. White (1926-2010) was an eminent neurosurgeon and bioethicist, renowned for his classic work in hypothermia and pioneering mammalian head transplant experiments. He founded the Division of Neurosurgery at the Cleveland Metropolitan General Hospital (currently MetroHealth Medical Center, a level 1 trauma county hospital) and became the youngest full professor at the Case Western Reserve University in Cleveland, Ohio. With over 500 research articles to his credit, he founded the Brain Research Laboratory at what was then the Cleveland Metropolitan General Hospital, which was also home to future leaders in neurosurgery, neurosciences, and allied specialties...
May 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29261689/an-improved-wrapper-based-feature-selection-method-for-machinery-fault-diagnosis
#6
Kar Hoou Hui, Ching Sheng Ooi, Meng Hee Lim, Mohd Salman Leong, Salah Mahdi Al-Obaidi
A major issue of machinery fault diagnosis using vibration signals is that it is over-reliant on personnel knowledge and experience in interpreting the signal. Thus, machine learning has been adapted for machinery fault diagnosis. The quantity and quality of the input features, however, influence the fault classification performance. Feature selection plays a vital role in selecting the most representative feature subset for the machine learning algorithm. In contrast, the trade-off relationship between capability when selecting the best feature subset and computational effort is inevitable in the wrapper-based feature selection (WFS) method...
2017: PloS One
https://www.readbyqxmd.com/read/29100506/long-term-in-vitro-culture-of-plasmodium-vivax-isolates-from-madagascar-maintained-in-saimiri-boliviensis-blood
#7
Rajeev K Mehlotra, D'Arbra Blankenship, Rosalind E Howes, Tovonahary A Rakotomanga, Brune Ramiranirina, Stephanie Ramboarina, Thierry Franchard, Marlin H Linger, Melinda Zikursh-Blood, Arsène C Ratsimbasoa, Peter A Zimmerman, Brian T Grimberg
BACKGROUND: Plasmodium vivax is the most prevalent human malaria parasite and is likely to increase proportionally as malaria control efforts more rapidly impact the prevalence of Plasmodium falciparum. Despite the prominence of P. vivax as a major human pathogen, vivax malaria qualifies as a neglected and under-studied tropical disease. Significant challenges bringing P. vivax into the laboratory, particularly the capacity for long-term propagation of well-characterized strains, have limited the study of this parasite's red blood cell (RBC) invasion mechanism, blood-stage development, gene expression, and genetic manipulation...
November 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28972383/research-prevalence-of-dense-bone-island
#8
Ali Zakir Syed, Savitha Deepthi Yannam, Gedela Pavani
OBJECTIVE: To determine the prevalence of dense bone island (DBI) and its relationship to age and sex; its predominant location, amount, and shape; and its correlation with resorption of roots. STUDY DESIGN: A retrospective chart review was done with panoramic images of 4581 patients above the age of 14 years at Case Western Reserve University School of Dental Medicine in northeast Ohio from January 2014 to May 2015. RESULTS: Of 4581 patients seen, 147 (3...
October 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28920007/towards-treatment-of-stargardt-disease-workshop-organized-and-sponsored-by-the-foundation-fighting-blindness
#9
REVIEW
Avery E Sears, Paul S Bernstein, Artur V Cideciyan, Carel Hoyng, Peter Charbel Issa, Krzysztof Palczewski, Philip J Rosenfeld, SriniVas Sadda, Ulrich Schraermeyer, Janet R Sparrow, Ilyas Washington, Hendrik P N Scholl
Accumulation of fluorescent metabolic byproducts of the visual (retinoid) cycle is associated with photoreceptor and retinal pigment epithelial cell death in both Stargardt disease and atrophic (nonneovascular) age-related macular degeneration (AMD). As a consequence of this observation, small molecular inhibitors of enzymes in the visual cycle were recently tested in clinical trials as a strategy to protect the retina and retinal pigment epithelium in patients with atrophic AMD. To address the clinical translational needs for therapies aimed at both diseases, a workshop organized by the Foundation Fighting Blindness was hosted by the Department of Pharmacology at Case Western Reserve University on February 17, 2017, at the Tinkham Veale University Center, Cleveland, OH, USA...
September 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28828153/effect-of-polyethelene-oxide-on-the-thermal-degradation-of-cellulose-biofilm-low-cost-material-for-soft-tissue-repair-in-dentistry
#10
Anna Akkus, Rakim Tyler, David Schiraldi, Renato Roperto, Fady Faddoul, Sorin Teich
BACKGROUND: Bio cellulose is a byproduct of sweet tea fermentation known as kombusha. During the biosynthesis by bacteria cellulose chains are polymerized by enzyme from activated glucose. The single chains are then extruded through the bacterial cell wall. Interestingly, a potential of the Kombucha's byproduct bio cellulose (BC) as biomaterial had come into focus only in the past few decades. The unique physical and mechanical properties such as high purity, an ultrafine and highly crystalline network structure, a superior mechanical strength, flexibility, pronounced permeability to gases and liquids, and an excellent compatibility with living tissue that reinforced by biodegradability, biocompatibility, large swelling ratios...
July 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28780738/john-p-craig-md-mph-physician-scientist-educator-and-mentor-1923-2016
#11
M A Haseeb, Pascal James Imperato
John P. Craig (1923-2016) was an eminent physician-scientist, gifted educator, and greatly valued mentor. Born in West Liberty, Ohio on 29 November 1923, he attended Oberlin College, and received his medical degree from Case Western Reserve University, School of Medicine. This was followed by an internship at Yale University Medical Center, and then service in the U.S. Army during the Korean War. He was a battalion surgeon, preventive medicine officer, and epidemiologist. While in Korea, he conducted important investigations of hemorrhagic fever among American troops...
October 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28772943/fault-diagnosis-for-rolling-bearings-under-variable-conditions-based-on-visual-cognition
#12
Yujie Cheng, Bo Zhou, Chen Lu, Chao Yang
Fault diagnosis for rolling bearings has attracted increasing attention in recent years. However, few studies have focused on fault diagnosis for rolling bearings under variable conditions. This paper introduces a fault diagnosis method for rolling bearings under variable conditions based on visual cognition. The proposed method includes the following steps. First, the vibration signal data are transformed into a recurrence plot (RP), which is a two-dimensional image. Then, inspired by the visual invariance characteristic of the human visual system (HVS), we utilize speed up robust feature to extract fault features from the two-dimensional RP and generate a 64-dimensional feature vector, which is invariant to image translation, rotation, scaling variation, etc...
May 25, 2017: Materials
https://www.readbyqxmd.com/read/28760280/effects-of-case-western-reserve-university-s-transverse-analysis-on-the-quality-of-orthodontic-treatment
#13
Raweya Yehya Mostafa, Rany M Bous, Mark G Hans, Manish Valiathan, Garrison E Copeland, Juan Martin Palomo
INTRODUCTION: The purpose of this study was to evaluate the effect of using the transverse analysis developed at Case Western Reserve University (CWRU) in Cleveland, Ohio. The hypotheses were based on the following: (1) Does following CWRU's transverse analysis improve the orthodontic results? (2) Does following CWRU's transverse analysis minimize the active treatment duration? METHODS: A retrospective cohort research study was conducted on a randomly selected sample of 100 subjects...
August 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28738127/early-onset-alzheimer-disease-and-candidate-risk-genes-involved-in-endolysosomal-transport
#14
Brian W Kunkle, Badri N Vardarajan, Adam C Naj, Patrice L Whitehead, Sophie Rolati, Susan Slifer, Regina M Carney, Michael L Cuccaro, Jeffery M Vance, John R Gilbert, Li-San Wang, Lindsay A Farrer, Christiane Reitz, Jonathan L Haines, Gary W Beecham, Eden R Martin, Gerard D Schellenberg, Richard P Mayeux, Margaret A Pericak-Vance
Importance: Mutations in APP, PSEN1, and PSEN2 lead to early-onset Alzheimer disease (EOAD) but account for only approximately 11% of EOAD overall, leaving most of the genetic risk for the most severe form of Alzheimer disease unexplained. This extreme phenotype likely harbors highly penetrant risk variants, making it primed for discovery of novel risk genes and pathways for AD. Objective: To search for rare variants contributing to the risk for EOAD. Design, Setting, and Participants: In this case-control study, whole-exome sequencing (WES) was performed in 51 non-Hispanic white (NHW) patients with EOAD (age at onset <65 years) and 19 Caribbean Hispanic families previously screened as negative for established APP, PSEN1, and PSEN2 causal variants...
September 1, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28628076/promoting-simulation-globally-networking-with-nursing-colleagues-across-five-continents
#15
Celeste M Alfes, Elizabeth A Madigan
Simulation education is gaining momentum internationally and may provide the opportunity to enhance clinical education while disseminating evidence-based practice standards for clinical simulation and learning. There is a need to develop a cohesive leadership group that fosters support, networking, and sharing of simulation resources globally. The Frances Payne Bolton School of Nursing at Case Western Reserve University has had the unique opportunity to establish academic exchange programs with schools of nursing across five continents...
July 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/28363483/restoration-of-reaching-and-grasping-movements-through-brain-controlled-muscle-stimulation-in-a-person-with-tetraplegia-a-proof-of-concept-demonstration
#16
A Bolu Ajiboye, Francis R Willett, Daniel R Young, William D Memberg, Brian A Murphy, Jonathan P Miller, Benjamin L Walter, Jennifer A Sweet, Harry A Hoyen, Michael W Keith, P Hunter Peckham, John D Simeral, John P Donoghue, Leigh R Hochberg, Robert F Kirsch
BACKGROUND: People with chronic tetraplegia, due to high-cervical spinal cord injury, can regain limb movements through coordinated electrical stimulation of peripheral muscles and nerves, known as functional electrical stimulation (FES). Users typically command FES systems through other preserved, but unrelated and limited in number, volitional movements (eg, facial muscle activity, head movements, shoulder shrugs). We report the findings of an individual with traumatic high-cervical spinal cord injury who coordinated reaching and grasping movements using his own paralysed arm and hand, reanimated through implanted FES, and commanded using his own cortical signals through an intracortical brain-computer interface (iBCI)...
May 6, 2017: Lancet
https://www.readbyqxmd.com/read/28166581/a-student-led-introduction-to-lesbian-gay-bisexual-and-transgender-health-for-first-year-medical-students
#17
Andrea M Grosz, Daniel Gutierrez, Andrea A Lui, Julia J Chang, Kathy Cole-Kelly, Henry Ng
BACKGROUND AND OBJECTIVES: Lesbian, gay, bisexual, and transgender (LGBT) individuals face significant health disparities. This is in part because many physicians are not sensitive to, and/or are underprepared to address, LGBT-specific concerns. To help meet this need, we, a group of second- and fourth-year medical students with faculty oversight, organized a session on LGBT health for first-year medical students. METHODS: The three second-year and one fourth-year student authors designed a mandatory session for the 167 first-years at Case Western Reserve University School of Medicine in Cleveland, OH...
January 2017: Family Medicine
https://www.readbyqxmd.com/read/28052061/integrated-genomic-characterization-of-oesophageal-carcinoma
#18
(no author information available yet)
Oesophageal cancers are prominent worldwide; however, there are few targeted therapies and survival rates for these cancers remain dismal. Here we performed a comprehensive molecular analysis of 164 carcinomas of the oesophagus derived from Western and Eastern populations. Beyond known histopathological and epidemiologic distinctions, molecular features differentiated oesophageal squamous cell carcinomas from oesophageal adenocarcinomas. Oesophageal squamous cell carcinomas resembled squamous carcinomas of other organs more than they did oesophageal adenocarcinomas...
January 12, 2017: Nature
https://www.readbyqxmd.com/read/28047693/we-fg-207b-11-objective-image-characterization-of-spectral-ct-with-a-dual-layer-detector
#19
O Ozguner, S Halliburton, A Dhanantwari, G Wen, S Utrup, D Jordan
PURPOSE: To obtain objective reference data for the spectral performance on a dual-layer detector CT platform (IQon, Philips) and compare virtual monoenergetic to conventional CT images. METHODS: Scanning was performed using the hospital's clinical adult body protocol: helical acquisition at 120kVp, with CTDIvol=15mGy. Multiple modules (591, 515, 528) of a CATPHAN 600 phantom and a 20 cm diameter cylindrical water phantom were scanned. No modifications to the standard protocol were necessary to enable spectral imaging...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047671/su-g-iep2-09-iodine-imaging-at-spectral-ct-with-a-dual-layer-detector
#20
O Ozguner, A Dhanantwari, S Halliburton, G Wen, S Utrup, D Jordan
PURPOSE: To evaluate the attenuation response of iodine and the accuracy of iodine quantification on a detector-based spectral CT scanner. METHODS: A Gammex 461A phantom was scanned using a dual-layer detector (IQon, Philips) at 120 kVp using helical acquisition with a CDTIvol of 15 mGy to approximate the hospital's clinical body protocol. No modifications to the standard protocol were necessary to enable spectral imaging. Iodine inserts at 6 concentrations (2, 5, 7...
June 2016: Medical Physics
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