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https://www.readbyqxmd.com/read/29142369/utility-of-18-f-fluorodeoxyglucose-positron-emission-tomography-magnetic-resonance-imaging-in-the-diagnosis-of-cardiac-paraganglioma
#1
Nicholas Bhojwani, Jennifer Huang, Vasant Garg, Michael Yang, Guilherme H Oliveira, Prabhakar Rajiah
Cardiac paragangliomas are rare tumors of neural crest origin, most frequently seen in the left atrium. There are mixed opinions regarding the most appropriate imaging study for diagnosis and evaluation. We describe the novel utility of 18-F-Fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in the case of a 42-year-old male with cardiac paraganglioma.
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29138942/calculation-of-left-ventricular-volumes-and-ejection-fraction-from-dynamic-cardiac-gated-15-o-water-pet-ct-5d-pet
#2
Jonny Nordström, Tanja Kero, Hendrik Johannes Harms, Charles Widström, Frank A Flachskampf, Jens Sörensen, Mark Lubberink
BACKGROUND: Quantitative measurement of myocardial blood flow (MBF) is of increasing interest in the clinical assessment of patients with suspected coronary artery disease (CAD). (15)O-water positron emission tomography (PET) is considered the gold standard for non-invasive MBF measurements. However, calculation of left ventricular (LV) volumes and ejection fraction (EF) is not possible from standard (15)O-water uptake images. The purpose of the present work was to investigate the possibility of calculating LV volumes and LVEF from cardiac-gated parametric blood volume (V B) (15)O-water images and from first pass (FP) images...
November 14, 2017: EJNMMI Physics
https://www.readbyqxmd.com/read/29137818/molecular-imaging-for-the-diagnosis-of-infective-endocarditis-a-systematic-literature-review-and-meta-analysis
#3
Daniel Juneau, Mohammad Golfam, Samir Hazra, Fernanda Erthal, Lionel S Zuckier, Jordan Bernick, George A Wells, Rob S B Beanlands, Benjamin J W Chow
BACKGROUND: Infective endocarditis (IE) is a serious, potentially life-threatening condition. Currently, the modified Duke criteria is used to assist with the diagnosis of IE, but it can still remain difficult. Growing data supports the potential use of molecular imaging to assist in the diagnosis of IE. Our objective was to understand the potential utility of (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography (PET-CT), (67)Ga citrate and radiolabeled white blood cell (WBC) scintigraphy in the diagnosis of IE...
November 8, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29130567/treatment-strategies-in-coronary-microvascular-dysfunction-a-systematic-review-of-interventional-studies
#4
Hannah E Suhrs, Marie M Michelsen, Eva Prescott
Coronary microvascular dysfunction has been associated with a wide spectrum of diseases and conditions, and it has proven to be a strong prognostic marker of morbidity and mortality. Despite increased attention guideline-based treatment recommendations are lacking. We performed a systematic review of pharmacological and non-pharmacological interventions to improve coronary perfusion, assessed by intracoronary Doppler, transthoracic Doppler echocardiography, positron emission tomography, cardiac magnetic resonance imaging, transthoracic contrast perfusion echocardiography and dilution techniques...
November 11, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/29122140/cardiac-tissue-characterization-and-imaging-in-autoimmune-rheumatic-diseases
#5
REVIEW
Sophie I Mavrogeni, Petros P Sfikakis, Loukia Koutsogeorgopoulou, George Markousis-Mavrogenis, Theodoros Dimitroulas, Genovefa Kolovou, George D Kitas
Inflammation, microvascular and macrovascular ischemia, valvular disease, and fibrosis are the main causes of cardiovascular disease (CVD) in autoimmune rheumatic diseases (ARDs). The silent presentation and the high mortality and/or morbidity of CVD in ARDs necessitate a reliable tool for early diagnosis. Noninvasive cardiovascular imaging, including echocardiography, nuclear imaging, cardiovascular computed tomography (CT), cardiac magnetic resonance (CMR), and hybrid imaging modalities, constitutes the main tool for monitoring of CVD in ARDs...
November 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29121750/novel-ecg-parameters-are-strongly-associated-with-inflammatory-18-f-fdg-pet-findings-in-patients-with-suspected-cardiac-sarcoidosis
#6
Kalle Sipilä, Heikki Tuominen, Atte Haarala, Antti Tikkakoski, Mika Kähönen, Kjell Nikus
BACKGROUND: (18)F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) is a feasible method to investigate the inflammatory activity of the myocardium in cardiac sarcoidosis. However, PET is costly and not as widely available as standard electrocardiogram (ECG). Current ECG findings related to cardiac sarcoidosis are highly non-specific. In this study, our aim was to determine whether novel ECG parameters are associated with pathological PET findings in patients with suspected cardiac sarcoidosis...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29119262/role-of-cardiac-pet-in-clinical-practice
#7
REVIEW
Brian M Salata, Parmanand Singh
Early identification of atherosclerosis and at-risk lesions plays a critical role in reducing the burden of cardiovascular disease. While invasive coronary angiography serves as the gold standard for diagnosing coronary artery disease, non-invasive imaging techniques provide visualization of both anatomical and functional atherosclerotic processes prior to clinical presentation. The development of cardiac positron emission tomography (PET) has greatly enhanced our capability to diagnose and treat patients with early stages of atherosclerosis...
November 9, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29101165/myocardial-contrast-echocardiography-in-mice-technical-and-physiological-aspects
#8
Melissa Verkaik, Erik van Poelgeest, Rick F J Kwekkeboom, Piet M Ter Wee, Charissa E van den Brom, Marc G Vervloet, Etto C Eringa
Myocardial contrast echocardiography (MCE) offers the opportunity to study myocardial perfusion defects in mice in detail. The value of MCE compared to SPECT, PET and CT consists of high spatial resolution, the possibility of quantification of blood volume and relatively low costs. Nevertheless, a number of technical and physiological aspects should be considered to ensure reproducibility among research groups. The aim of this overview is to describe technical aspects of MCE and the physiological parameters that influence myocardial perfusion data obtained with this technique...
November 3, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29096007/diagnosis-of-active-pericarditis-by-positron-emission-tomography-pet-cardiac-magnetic-resonance-cmr-imaging
#9
Bo Xu, Steve Shih-Lin Huang, Christine Jellis, Scott D Flamm
No abstract text is available yet for this article.
October 31, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29095701/impact-of-motion-compensation-and-partial-volume-correction-for-sup-18-sup-f-naf-pet-ct-imaging-of-coronary-plaque
#10
Jacobo Cal-Gonzalez, Charalampos Harry Tsoumpas, Martin Lyngby Lassen, Sazan Rasul, Lorenz Koller, Marcus Hacker, Klaus P Schäfers, Thomas Beyer
Recent studies have suggested that <sup>18</sup>F-NaF-PET enables visualization and quantification of plaque micro-calcification in the coronary tree. However, PET imaging of plaque calcification in the coronary arteries is challenging because of the respiratory and cardiac motion as well as partial volume effects. The objective of this work is to implement an image reconstruction framework, which incorporates compensation for respiratory as well as cardiac motion (MoCo) and partial volume correction (PVC), for cardiac <sup>18</sup>F-NaF PET imaging in PET/CT...
November 2, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29094295/patient-page-sarcoidosis-imaging
#11
John P Bois, Panithaya Chareonthaitawee
Optimizing our imaging capabilities for patients with cardiac sarcoidosis is critical as it has diagnostic, prognostic, and therapeutic implications. (18)FDG PET/CT has the highest sensitivity for the detection of CS but requires specific dietary preparation that is difficult for patients to follow which may lead to ineffective suppression of physiologic (18)FDG uptake. This may result in inconclusive scan results in up to 30% of patients undergoing (18)FDG PET/CT imaging for CS. Therefore, it is imperative that we relay to our patients the importance of dietary preparation for CS PET imaging and then provide simple, easy to follow instructions for them...
November 1, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29089819/2017-multimodality-appropriate-use-criteria-for-noninvasive-cardiac-imaging-expert-consensus-of-the-asian-society-of-cardiovascular-imaging
#12
REVIEW
Kyongmin Sarah Beck, Jeong A Kim, Yeon Hyeon Choe, Sim Kui Hian, John Hoe, Yoo Jin Hong, Sung Mok Kim, Tae Hoon Kim, Young Jin Kim, Yun Hyeon Kim, Sachio Kuribayashi, Jongmin Lee, Lilian Leong, Tae-Hwan Lim, Bin Lu, Jae Hyung Park, Hajime Sakuma, Dong Hyun Yang, Tan Swee Yaw, Yung-Liang Wan, Zhaoqi Zhang, Shihua Zhao, Hwan Seok Yong
In 2010, the Asian Society of Cardiovascular Imaging (ASCI) provided recommendations for cardiac CT and MRI, and this document reflects an update of the 2010 ASCI appropriate use criteria (AUC). In 2016, the ASCI formed a new working group for revision of AUC for noninvasive cardiac imaging. A major change that we made in this document is the rating of various noninvasive tests (exercise electrocardiogram, echocardiography, positron emission tomography, single-photon emission computed tomography, radionuclide imaging, cardiac magnetic resonance, and cardiac computed tomography/angiography), compared side by side for their applications in various clinical scenarios...
November 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29076915/intracardiac-metastases-detected-by-18f-fspg-pet-ct
#13
Meaghan A Magarik, Ronald C Walker, Jill Gilbert, H Charles Manning, Pierre P Massion
PET/CT imaging is frequently used for cancer diagnosis and restaging as metabolically active cells, including cancer, utilize glucose for proliferation. F-FDG is the most commonly utilized radiopharmaceutical in PET/CT imaging. Limitations of F-FDG imaging include intense physiologic uptake in benign tissues such as the brain and myocardium. We present a case of non-small cell lung cancer with myocardial and pericardial metastases obscured by physiologic F-FDG cardiac uptake but detected with the investigational PET radiotracer (4S)-4-(3-F-fluoropropyl)-L-glutamate (F-FSPG), which targets a pathway associated with glutathione biosynthesis...
October 26, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29073808/whole-body-biodistribution-dosimetry-and-metabolite-correction-of-11-c-palmitate-a-pet-tracer-for-imaging-of-fatty-acid-metabolism
#14
Nana L Christensen, Steen Jakobsen, Anna C Schacht, Ole L Munk, Aage K O Alstrup, Lars P Tolbod, Hendrik J Harms, Søren Nielsen, Lars C Gormsen
INTRODUCTION: Despite the decades long use of [(11)C]palmitate positron emission tomography (PET)/computed tomography in basic metabolism studies, only personal communications regarding dosimetry and biodistribution data have been published. METHODS: Dosimetry and biodistribution studies were performed in 2 pigs and 2 healthy volunteers by whole-body [(11)C]palmitate PET scans. Metabolite studies were performed in 40 participants (healthy and with type 2 diabetes) under basal and hyperinsulinemic conditions...
January 2017: Molecular Imaging
https://www.readbyqxmd.com/read/29072629/a-score-based-approach-to-18-f-fdg-pet-images-as-a-tool-to-describe-metabolic-predictors-of-myocardial-doxorubicin-susceptibility
#15
Matteo Bauckneht, Silvia Morbelli, Francesco Fiz, Giulia Ferrarazzo, Roberta Piva, Alberto Nieri, Matteo Sarocchi, Paolo Spallarossa, Maria Elisa Canepari, Eleonora Arboscello, Andrea Bellodi, Massimo Massaia, Andrea Gallamini, Paolo Bruzzi, Cecilia Marini, Gianmario Sambuceti
PURPOSE: To verify the capability of (18)F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) to identify patients at higher risk of developing doxorubicin (DXR)-induced cardiotoxicity, using a score-based image approach. METHODS: 36 patients underwent FDG-PET/CT. These patients had shown full remission after DXR-based chemotherapy for Hodgkin's disease (DXR dose: 40-50 mg/m² per cycle), and were retrospectively enrolled. Inclusion criteria implied the presence of both pre- and post-chemotherapy clinical evaluation encompassing electrocardiogram (ECG) and echocardiography...
October 26, 2017: Diagnostics
https://www.readbyqxmd.com/read/29061522/prognostic-value-of-fluorine-18-fluoro-2-deoxyglucose-positron-emission-computed-tomography-in-patients-with-unexplained-atrioventricular-block
#16
Tamiruddin A Danwade, Soumen Devidutta, Abhijeet B Shelke, Daljeet Kaur Saggu, Sachin D Yalagudri, Chennapragada Sridevi, Nallamala Krishna Reddy, Calambur Narasimhan
BACKGROUND: The cause of atrioventricular conduction block (AVB) remains unexplained in a significant number of patients. Granulomatous myocarditis (GM) is an uncommon but important cause of AVB. Fluorine-18 fluoro-2-deoxyglucose positron emission computed tomography (18-FDG PET) scan has emerged as a sensitive tool for diagnosing GM. OBJECTIVES: The objective of this study was to evaluate the prognostic value of 18-FDG PET scan in patients with unexplained AVB...
October 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29057029/transthyretin-cardiac-amyloidosis-in-older-adults-optimizing-cardiac-imaging-to-the-corresponding-diagnostic-and-management-goal
#17
Adam Castaño, Daniel K Manson, Mathew S Maurer, Sabahat Bokhari
PURPOSE OF REVIEW: Transthyretin cardiac amyloidosis is increasingly recognized as an important cause of heart failure in older adults. Many cardiac imaging modalities have evolved to evaluate transthyretin cardiac amyloidosis and include 2D echocardiography with tissue Doppler and speckle-strain imaging, nuclear scintigraphy, cardiac magnetic resonance imaging, and positron emission tomography. The purpose of this review is to highlight the optimal selection of advanced cardiac imaging techniques with corresponding diagnostic goals including raising suspicion, making an early diagnosis, and subtyping transthyretin cardiac amyloid, as well as management goals including assessment of ventricular impairment, prognosticating, and monitoring disease progression...
June 2017: Current Cardiovascular Risk Reports
https://www.readbyqxmd.com/read/29052535/large-cell-neuroendocrine-carcinoma-of-the-kidney-with-cardiac-metastasis-a-case-report
#18
Moeka Shimbori, Kimito Osaka, Takashi Kawahara, Ryo Kasahara, Sayuki Kawabata, Kazuhide Makiyama, Keiichi Kondo, Noboru Nakaigawa, Shoji Yamanaka, Masahiro Yao
BACKGROUND: Primary large cell neuroendocrine carcinoma of the kidney is a rare and generally very aggressive disease. We present a case of a patient with primary large cell neuroendocrine carcinoma of the kidney with cardiac metastasis. CASE PRESENTATION: A 59-year-old Japanese man presented to his previous physician with hematuria. Computed tomography revealed masses in the heart and right kidney, and fluorodeoxyglucose-positron emission tomography showed abnormal uptake in the heart...
October 20, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29052526/cardiac-magnetic-resonance-imaging-indeterminate-negative-cardiac-sarcoidosis-revealed-by-18-f-fluorodeoxyglucose-positron-emission-tomography-two-case-reports-and-a-review-of-the-literature
#19
S C Sasson, R Russo, T Chung, G Chu, I Hunyor, J Williamson, A Murad, A Kane, S Riminton, S Limaye
BACKGROUND: Sarcoidosis is an inflammatory disorder of immune dysregulation characterized by non-caseating granulomas that can affect any organ. Cardiac sarcoidosis is an under-recognized entity that has a heterogeneous presentation and may occur independently or with any severity of systemic disease. Diagnosing cardiac sarcoidosis remains problematic with endomyocardial biopsies associated with a high risk of complications. Several diagnostic algorithms are currently available that rely on histopathology or clinical and radiological measures...
October 20, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29051345/reply-utilizing-and-interpreting-fdg-pet-ct-images-in-patients-referred-for-assessment-of-cardiac-sarcoidosis-the-devil-is-in-the-details
#20
David Birnie, Hiroshi Ohira, Rob Beanlands
No abstract text is available yet for this article.
October 19, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
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