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https://www.readbyqxmd.com/read/28626303/the-comparison-of-clinical-features-and-quality-of-life-after-total-knee-replacement
#1
Jiyeon Lee, Jung-Hee Kim, Eun-Jung Jung, Byoung-Hee Lee
[Purpose] The purpose of this study is to provide fundamental information for efficient management of patients after a total knee replacement (TKR) through the evaluation of changes of range of motion, pain, functional level, and quality of life. [Subjects and Methods] For a total of 63 knee osteoarthritis patients, VAS, KSKS, KSFS, HSS, WOMAC scores and quality of life were evaluated for functional levels at pre-operation, post-operation, six months after operation, and 12 months after operation. [Results] After the TKR operations, participants showed significant improvement in KSKS, KSFS, WOMAC, and SF-36 scores when compared to pre-operation...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28622843/fatal-pulmonary-embolism-following-elective-total-knee-replacement-using-aspirin-in-multi-modal-prophylaxis-a-12year-study
#2
C Quah, E Bayley, N Bhamber, P Howard
BACKGROUND: The National Institute for Health and Clinical Excellence (NICE) has issued guidelines on which thromboprophylaxis regimens are suitable following lower limb arthroplasty. Aspirin is not a recommended agent despite being accepted in orthopaedic guidelines elsewhere. We assessed the incidence of fatal pulmonary embolism (PE) and all-cause mortality following elective primary total knee replacement (TKR) with a standardised multi-modal prophylaxis regime in a large teaching district general hospital...
June 13, 2017: Knee
https://www.readbyqxmd.com/read/28615121/implications-of-the-getting-it-right-first-time-initiative-for-regional-knee-arthroplasty-services
#3
Richard Barksfield, James Murray, James Robinson, Andrew Porteous
STUDY AIM: The aim of this case study of regional orthopaedic practice was to estimate the potential impact of the GIRFT recommendations (iGIRFT) of minimum unit and surgeon specific volumes to orthopaedic units within the Severn Region, UK. METHOD: Practice profiles for surgeons and units were generated using the UK National Joint Registry Surgeon and Hospital Profile Database. Minimum volume thresholds were set at 13 procedures/year for surgeons and 30 procedures/year for units...
June 11, 2017: Knee
https://www.readbyqxmd.com/read/28606159/thresholds-for-oxford-knee-score-after-total-knee-replacement-surgery-a-novel-approach-to-post-operative-evaluation
#4
Christian Lund Petersen, Jonas Bruun Kjærsgaard, Nicolai Kjærgaard, Michael Ulrich Jensen, Mogens Berg Laursen
BACKGROUND: In a prospective cohort study, we wanted to detect thresholds distinguishing between patients with a satisfactory and an unsatisfactory outcome after total knee replacement (TKR) based on Patient-Reported Outcome Measures (PROMs), namely the Oxford Knee Score (OKS), using patient satisfaction and patient-perceived function as global transition items. METHODS: Seventy-three TKR patients completed the OKS questionnaire before surgery and were invited to complete the same questionnaire again 6 (4 to 9) months after surgery...
June 12, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28597247/pre-operative-predictors-of-post-operative-falls-in-people-undergoing-total-hip-and-knee-replacement-surgery-a-prospective-study
#5
Pazit Levinger, Elin Wee, Soula Margelis, Hylton B Menz, John R Bartlett, Neil R Bergman, Stephen McMahon, Keith D Hill
INTRODUCTION: Pain and disability often persist following hip (THR) and knee replacement (TKR) surgery predisposing patients to increased risk of falling. This study identified pre-operative predictors for post-operative falls in TKR and THR patients, and the incidence and circumstances of falls in the 12 months post-surgery. MATERIALS AND METHODS: A survey was undertaken of patients before THR and TKR, and was repeated 12 months post-operation. The survey included (1) medical history and medications usage, (2) pain and function, (3) health-related and physical activity and (4) fear of falls and history of falls questionnaires...
June 8, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28578438/predictors-of-blood-transfusion-following-total-knee-replacement-at-a-tertiary-care-center-in-central-saudi-arabia
#6
Abdullah A Al-Turki, Abdulaziz K Al-Araifi, Bshaer A Badakhan, Mohammed T Al-Nazzawi, Suliman Alghnam, Abdulaziz S Al-Turki
To examine the incidence and predictors of blood transfusion following total knee replacement (TKR). Methods: A retrospective study on 462 patients of primary TKR at National Guard Hospital, Riyadh, Kingdom of Saudi Arabia. Descriptive statistics were compared by blood transfusion status and significant variables were further included in the multivariable model. Results: Overall transfusion rate following TKR was 35.3%. Regression analyses identified bilateral surgery, low preoperative hemoglobin (Hb) level, and high amount of blood loss as predictors of blood transfusion...
June 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28576685/aberrant-dna-methylation-patterns-of-human-spermatozoa-in-current-smoker-males
#7
M Laqqan, S Tierling, Y Alkhaled, C Lo Porto, E F Solomayer, M E Hammadeh
The purpose of this study was to investigate the impact of current cigarette smoking on sperm DNA methylation patterns. A total of 108 males (51 current smokers and 57 never smoked males) were included in the study. Using 450 BeadChip Arrays, the differentially methylated CpGs between current smokers (n=15) and never smoked males (n=15) were identified. Out of significantly 11 CpGs identified, 2 CpGs namely cg07869343 and cg19169023, which are located in the MAPK8IP3 and TKR genes were selected for further analysis...
May 30, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28567148/hip-abductor-strengthening-improves-physical-function-following-total-knee-replacement-one-year-follow-up-of-a-randomized-pilot-study
#8
Karvannan Harikesavan, Raj D Chakravarty, Arun G Maiya, Sanjay P Hegde, Shivakumar Y Shivanna
BACKGROUND: Total knee replacement (TKR) is the commonest surgical procedure for patients with severe pain and impaired physical function following end stage knee osteoarthritis. The hip abductors are well renowned in stabilization of the trunk and hip during walking, maintaining the lower limb position, and transferring the forces from the lower limbs to the pelvis. OBJECTIVE: To assess the efficacy of hip abductor strengthening exercise on functional outcome using performance based outcome measures following total knee replacement...
2017: Open Rheumatology Journal
https://www.readbyqxmd.com/read/28562150/preoperative-psychosocial-risk-factors-for-poor-outcomes-at-1-and-5-years-after-total-knee-replacement
#9
Vikki Wylde, Lea Trela-Larsen, Michael R Whitehouse, Ashley W Blom
Background and purpose - Psychosocial factors are important risk factors for poor outcomes in the first year after total knee replacement (TKR), however their impact on long-term outcomes is unclear. We aimed to identify preoperative psychosocial risk factors for poor outcomes at 1 year and 5 years after TKR. Patients and methods - 266 patients were recruited prior to TKR surgery. Knee pain and function were assessed preoperatively and at 1 and 5 years postoperative using the WOMAC Pain score, WOMAC Function score and American Knee Society Score (AKSS) Knee score...
May 31, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28558029/association-of-anterior-cruciate-ligament-injury-with-knee-osteoarthritis-and-total-knee-replacement-a-retrospective-cohort-study-from-the-taiwan-national-health-insurance-database
#10
Sheng-Hsiung Lin, Ting-Chuan Wang, Chun-Fu Lai, Ru-Yin Tsai, Chih-Ping Yang, Chih-Shung Wong
OBJECTIVE: This study aimed to support the potential protective role of anterior cruciate ligament (ACL) reconstruction against the development of osteoarthritis (OA). METHODS: In this retrospective cohort study, the long-term results of ACL reconstruction in Taiwan were evaluated based on data from the National Health Insurance Research Database (NHIRD). In total, 8,769 eligible cases were included from 11,921 ACL-injured patients. The cumulative incidence rates of OA and total knee replacement (TKR) were analyzed using the Kaplan-Meier estimator...
2017: PloS One
https://www.readbyqxmd.com/read/28553451/the-use-of-dual-reconstruction-plates-for-failed-fixation-of-patellar-fracture-after-total-knee-replacement-a-case-report
#11
P Sa-Ngasoongsong, K Chulsomlee, S Wongsak, C Suphachatwong, V Kawinwonggowit
Patellar fracture after total knee replacement (TKR) is one of the challenging problems in periprosthetic fracture. Open reduction with internal fixation (ORIF), as tension band wiring (TBW), usually required in cases with extensor mechanism disruption. However, many studies reported a high failure rate after using this technique. In this report, we presented an interesting case of periprosthetic patellar fracture after TKR with TBW failure that was successfully treated with double non-locking reconstruction plates fixation and TBW augmentation...
November 2016: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28552448/surgeon-s-preference-in-total-knee-replacement-a-quantitative-examination-of-attributes-reasons-for-alteration-and-barriers-to-change
#12
Christopher J Vertullo, Peter M Grimbeek, Stephen E Graves, Peter L Lewis
BACKGROUND: The reasons why surgeons prefer a particular total knee replacement (TKR) to other viable options with lower cost or lower revision risk remain uncertain. This study examined the concept of surgeon's preference in TKR; including the self-assigned utility of their preferred prosthesis, reasons to alter usual preference and barriers to permanently changing preference. METHODS: Using a multinational electronic survey, 347 TKR performing orthopedic surgeons were studied using anonymous mandatory responses, mutually exclusive closed options, multiple responses blocking, automatic stem randomization, Likert scale weighting, and an absence of neutral options...
April 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28551201/multifactorial-analysis-of-dissatisfaction-after-primary-total-knee-replacement
#13
Kunal Dhurve, Corey Scholes, Sherif El-Tawil, Aseem Shaikh, Lai Kah Weng, Kumbelin Levin, Brett Fritsch, David Parker, Myles Coolican
BACKGROUND: The aims of this study were to identify the prevalence and causes of dissatisfaction in a cohort of private practice patients, and to compare the psychological characteristics of dissatisfied patients to matched, satisfied controls. METHODS: Unilateral TKR patients were evaluated to identify those dissatisfied with their TKR. Dissatisfied and satisfied patients were matched in terms of age, gender, follow-up duration and body mass index (BMI). Psychological evaluation was performed using the Pain Catastrophizing Scale (PCS), Depression, Anxiety and Stress Scale (DASS) and the Multidimensional Health Locus of Control (MHLC) scale...
May 24, 2017: Knee
https://www.readbyqxmd.com/read/28548313/total-knee-replacement-are-there-any-baseline-factors-that-have-influence-in-patient-reported-outcomes
#14
A Escobar, L García Pérez, C Herrera-Espiñeira, F Aizpuru, C Sarasqueta, M Gonzalez Sáenz de Tejada, J M Quintana, A Bilbao
BACKGROUND: There is conflicting evidence about what factors influence outcomes after total knee replacement (TKR). The objective is to identify baseline factors that differentiate patients who achieve both, minimal clinically important difference (MCID) and a patient acceptable symptom state (PASS) in pain and function, measured by WOMAC, after TKR from those who do not attain scores above the cutoff in either of these dimensions. METHODS: One-year prospective multicentre study...
May 26, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28539693/quality-based-procedures-for-knee-replacement-hip-replacement-and-hip-fracture-physiotherapists-perceptions-of-adherence-barriers-and-facilitators
#15
Kirsti J E Reinikka, Denise Taylor, Sylvia Daniel, Stacey Burns-Hogan, Brittany DePass, Laura McGill, Michael McLeod, Susan Safadi, Sandy Veit
Purpose: This mixed-methods study examined the perceived barriers to and facilitators of implementing best-practice guidelines (BPGs) and adhering to provincial Quality-Based Procedures (QBPs) by Ontario physiotherapists working with patients after total knee replacement (TKR), total hip replacement (THR), and hip fracture (HF). Method: Using snowball sampling, 93 hospital and home care physiotherapists working with patients after TKR, THR, or HF completed a Web-based survey. A subset of these participated in follow-up semi-structured telephone interviews...
2017: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/28536660/sorafenib-associated-heart-failure-complicated-by-cardiogenic-shock-after-treatment-of-advanced-stage-hepatocellular-carcinoma-a-clinical-case-discussion
#16
Candace Wu, Kamal Shemisa
Background. Sorafenib, an oral tyrosine kinase inhibitor (TKI), targets multiple tyrosine kinase receptors (TKRs) involved in angiogenesis and tumor growth. Studies suggest that inhibition of TKR impacts cardiomyocyte survival. Inhibition of VEGF signaling interrupts angiogenesis and is associated with the development of hypertension and compensatory hypertrophy. Compensated hypertrophy ultimately leads to heart failure. Case Description. A 76-year-old man with a past medical history of systolic heart failure due to ischemic cardiomyopathy and stage IIIC hepatocellular carcinoma (HCC) presented with symptoms of decompensated heart failure...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28521834/incidence-of-total-hip-or-knee-replacement-due-to-osteoarthritis-in-relation-to-thyroid-function-a-prospective-cohort-study-the-nord-tr%C3%A3-ndelag-health-study
#17
Alf Inge Hellevik, Marianne Bakke Johnsen, Arnulf Langhammer, Anne Marie Fenstad, Ove Furnes, Kjersti Storheim, John Anker Zwart, Gunnar Flugsrud, Lars Nordsletten
BACKGROUND: To study whether thyroid function was associated with risk of hip or knee replacement due to primary osteoarthritis. METHODS: In a prospective cohort study, data from the second and third survey of the Nord-Trøndelag Health Study were linked to the Norwegian Arthroplasty Register in order to identify total hip or knee replacement as a result of primary osteoarthritis. RESULTS: Among 37 891 participants without previously known thyroid disease we recorded 978 total hip replacements (THRs) and 538 total knee replacements (TKRs) during a median follow-up time of 15...
May 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28500496/patient-specific-instrumentation-improves-alignment-of-lateral-unicompartmental-knee-replacements-by-novice-surgeons
#18
Chin Ting Justin Ng, Simon Newman, Simon Harris, Susannah Clarke, Justin Cobb
PURPOSE: Patient-specific instrumentation (PSI) has the potential to offer numerous benefits-not least of all, improved resection accuracy; but its potential has not been realised in clinical studies. An explanation may be the focus of such studies on the total knee replacement (TKR-a common procedure, with which surgeons are generally very familiar. Consequently, we sought to investigate the potential role of PSI in guiding novice surgeons to perform the more technically demanding and less familiar lateral unicondylar knee replacement (LUKR)...
May 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28492106/higher-risk-of-revision-for-infection-using-systemic-clindamycin-prophylaxis-than-with-cloxacillin
#19
Otto Robertsson, Olof Thompson, Annette W-Dahl, Martin Sundberg, Lars Lidgren, Anna Stefánsdóttir
Background and purpose - Clindamycin has not been compared with other antibiotics for prophylaxis in arthroplasty. Since 2009, the Swedish Knee Arthroplasty Register (SKAR) has been collecting information on the prophylactic antibiotic regime used at every individual operation. In Sweden, when there is allergy to penicillin, clindamycin has been the recommended alternative. We examined whether there were differences in the rate of revision due to infection depending on which antibiotic was used as systemic prophylaxis...
May 11, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28476062/patient-reported-outcomes-following-single-and-multiple-radius-total-knee-replacement-a-randomized-controlled-trial
#20
Nadeem Mushtaq, Alexander D Liddle, David Isaac, Katherine Dillow, Paul Gill
Although single-radius (SR) designs of total knee replacement (TKR) have theoretical benefits, the clinical advantage conferred by such designs is unknown. The aim of this randomized, controlled study was to compare the short-term clinical outcomes of the two design rationales. A total of 105 knees were randomized to receive either a single radius (Scorpio, Stryker; SR Group) or multiple radius (AGC, Zimmer Biomet; MR group) TKR. Patient-reported outcomes (Oxford Knee Score [OKS] and Knee Society Score [KSS]) were collected at 6 weeks, 6 months, and 1 year following surgery...
May 5, 2017: Journal of Knee Surgery
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