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https://www.readbyqxmd.com/read/27916326/corrigendum-to-what-is-the-effect-of-sensori-motor-training-on-functional-outcome-and-balance-performance-of-patients-undergoing-tkr-a-systematic-review-physiotherapy-102-2016-136-144
#1
M Moutzouri, N Gleeson, E Billis, I Panoutsopoulou, J Gliatis
No abstract text is available yet for this article.
December 1, 2016: Physiotherapy
https://www.readbyqxmd.com/read/27893033/effect-of-a-decision-aid-on-access-to-total-knee-replacement-for-black-patients-with-osteoarthritis-of-the-knee-a-randomized-clinical-trial
#2
Said A Ibrahim, Marissa Blum, Gwo-Chin Lee, Pekka Mooar, Elina Medvedeva, Aliya Collier, Diane Richardson
Importance: Black patients with advanced osteoarthritis (OA) of the knee are significantly less likely than white patients to undergo surgery. No strategies have been proved to improve access to surgery for black patients with end-stage OA of the knee. Objective: To assess whether a decision aid improves access to total knee replacement (TKR) surgery for black patients with OA of the knee. Design, Setting, and Participants: In a randomized clinical trial, 336 eligible participants who self-identified as black and 50 years or older with chronic and frequent knee pain, a Western Ontario McMaster Universities Osteoarthritis Index score of at least 39, and radiographic evidence of OA of the knee were recruited from December 1, 2010, to May 31, 2014, at 3 medical centers...
November 23, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27868384/post-acute-rehabilitation-after-total-knee-replacement-a-multicentre-randomized-clinical-trial-comparing-long-term-outcomes
#3
Marlene Fransen, Lillias Nairn, Lisa Bridgett, Jack Crosbie, Lyn March, David Parker Mbbs, Ross Crawford, Alison R Harmer
OBJECTIVE: To evaluate the long-term benefit of providing a post-acute outpatient group exercise program for patients following primary total knee replacement (TKR) surgery for osteoarthritis. METHODS: A multicenter randomized clinical trial conducted in 12 Australian public and private hospital centers. A total of 422 participants, aged 45 to 75 years, were randomly allocated prior to hospital discharge to the post-acute group exercise program or usual care and were assessed six weeks, six months and 12 months after surgery...
November 21, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27856293/substantial-rise-in-the-lifetime-risk-of-primary-total-knee-replacement-surgery-for-osteoarthritis-from-2003-to-2013-an-international-population-level-analysis
#4
I N Ackerman, M A Bohensky, R de Steiger, C A Brand, A Eskelinen, A M Fenstad, O Furnes, G Garellick, S E Graves, J Haapakoski, L I Havelin, K Mäkelä, F Mehnert, A Becic Pedersen, O Robertsson
OBJECTIVE: To estimate and compare the lifetime risk of total knee replacement surgery (TKR) for osteoarthritis (OA) between countries, and over time. METHOD: Data on primary TKR procedures performed for OA in 2003 and 2013 were extracted from national arthroplasty registries in Australia, Denmark, Finland, Norway and Sweden. Life tables and population data were also obtained for each country. Lifetime risk of TKR was calculated for 2003 and 2013 using registry, life table and population data...
November 14, 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/27837186/computed-tomography-is-not-necessary-to-assess-rotation-of-the-femoral-component-in-navigation-assisted-total-knee-replacement
#5
Daniel Hernández-Vaquero, Alfonso Noriega-Fernandez, Ivan Perez-Coto, Manuel A Sandoval García, Andres A Sierra-Pereira, Sergio Roncero-Gonzalez, Jose Manuel Fernandez-Carreira
OBJECTIVE: To demonstrate that postoperative computed tomography (CT) is not needed if navigation is used to determine the rotational position of the femoral component during total knee replacement (TKR). METHODS: Preoperative CT, navigational, and postoperative CT data of 70 TKR procedures were analysed. The correlation between the rotational angulation of the femur measured by CT and that measured by perioperative navigation was examined. The correlation between the femoral component rotation determined by navigation and that determined by CT was also assessed...
November 10, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27824655/-fear-of-the-known-and-unknown-factors-affecting-participation-following-knee-replacement-among-persons-with-participation-restriction
#6
Jessica Maxwell, Molly Vaughan, Aileen Ledingham, David Felson, Julie Keysor
BACKGROUND/PURPOSE: Evidence suggests that more than 30% of patients post-total knee replacement (TKR) are living with participation restrictions, yet little is known about their perceptions of and factors contributing to these restrictions. The purpose of this study was to identify emergent or recurring themes behind participation restrictions after TKR. METHODS: Nineteen participants between 50 and 85 years old reporting participation restrictions 1 to 5 years post-TKR completed semistructured qualitative interviews about their participation experience after TKR...
November 7, 2016: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/27818976/does-the-suction-drain-diameter-matter-bleeding-analysis-after-total-knee-replacement-comparing-different-suction-drain-gauges
#7
Marcos George de Souza Leao, Gladys Martins Pedroza Neta, Thiago Montenegro da Silva, Yacov Machado Costa Ferreira, Waryla Raissa Vasconcelos Dias
OBJECTIVES: To evaluate bleeding and the estimated blood loss in patients who underwent total knee replacement (TKR) with different closed suction drains (3.2-mm and 4.8-mm gauge). METHODS: This was a randomized controlled trial with 22 patients who underwent TKR and were divided into two groups: Group I, with 11 patients in whom the 3.2-mm suction drain was used, and Group II, with 11 patients in whom the 4.8-mm suction drain was used. The hematocrit was measured after 24, 48 and 72 h after surgery in order to calculate the estimated blood loss...
September 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/27790392/is-total-knee-replacement-justified-in-the-morbidly-obese-a-systematic-review
#8
Raju Vaishya, Vipul Vijay, David Wamae, Amit Kumar Agarwal
Total knee replacement (TKR) comprises a significant, growing aspect in the management of patients with advanced arthritis of the knee for which conservative medical therapy has failed. Obesity, a rising epidemic, is considered an important independent risk factor in the development of osteoarthritis (OA). An aging population and increasing incidence of obesity contribute to a higher prevalence of OA and a subsequent greater need for TKR. The numbers of morbidly obese (MO) people undergoing TKR has consistently been rising...
September 23, 2016: Curēus
https://www.readbyqxmd.com/read/27761443/patient-satisfaction-at-2-months-following-total-knee-replacement-using-a-second-generation-medial-pivot-system-follow-up-of-250-consecutive-cases
#9
Philippe P Van Overschelde, David A Fitch
BACKGROUND: Patient dissatisfaction following total knee replacement (TKR) has been reported as high as 24%. Most previous studies have focused on satisfaction for TKR overall, with few reporting satisfaction for specific implant designs. The purpose of this study was to assess patient satisfaction for TKRs performed using a second generation medial-pivot system (EVOLUTION(®), MicroPort Orthopedics Inc., Arlington, TN, USA). METHODS: Of a single surgeon's first 250 consecutive TKRs performed using the subject system, 224 completed a patient satisfaction assessment, the Knee Injury and Osteoarthritis Outcome Score (KOOS), range of motion, and radiographs at 2 months follow-up...
September 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27757426/tie2-mediated-tyrosine-phosphorylation-of-h4-regulates-dna-damage-response-by-recruiting-abl1
#10
Mohammad B Hossain, Rehnuma Shifat, David G Johnson, Mark T Bedford, Konrad R Gabrusiewicz, Nahir Cortes-Santiago, Xuemei Luo, Zhimin Lu, Ravesanker Ezhilarasan, Erik P Sulman, Hong Jiang, Shawn S C Li, Frederick F Lang, Jessica Tyler, Mien-Chie Hung, Juan Fueyo, Candelaria Gomez-Manzano
DNA repair pathways enable cancer cells to survive DNA damage induced after genotoxic therapies. Tyrosine kinase receptors (TKRs) have been reported as regulators of the DNA repair machinery. TIE2 is a TKR overexpressed in human gliomas at levels that correlate with the degree of increasing malignancy. Following ionizing radiation, TIE2 translocates to the nucleus, conferring cells with an enhanced nonhomologous end-joining mechanism of DNA repair that results in a radioresistant phenotype. Nuclear TIE2 binds to key components of DNA repair and phosphorylates H4 at tyrosine 51, which, in turn, is recognized by the proto-oncogene ABL1, indicating a role for nuclear TIE2 as a sensor for genotoxic stress by action as a histone modifier...
April 2016: Science Advances
https://www.readbyqxmd.com/read/27748254/retrospective-comparison-of-functional-and-radiological-outcome-between-two-contemporary-high-flexion-knee-designs
#11
Vikash Kapoor, Daipayan Chatterjee, Sutanu Hazra, Anirban Chatterjee, Parag Garg, Kaustav Debnath, Soham Mandal, Sudipto Sarkar
INTRODUCTION: Patient satisfaction after total knee replacement (TKR) depends on the amount of pain relief and the functional activities achieved. An important criterion of good functional outcome is the amount of flexion achieved and whether the patient can manage high flexion activities. In order to increase the amount of safe flexion, various implant designs have been developed. This study aims to compare the outcome after TKR using two contemporary high flexion knee designs: Sigma CR150 High Flex Knee prosthesis (Depuy, Warsaw, Indiana) and NexGen High Flex Knee prosthesis (Zimmer, Warsaw, Indiana)...
2016: SICOT-J
https://www.readbyqxmd.com/read/27745873/stress-shielding-in-periprosthetic-bone-following-a-total-knee-replacement-effects-of-implant-material-design-and-alignment
#12
Qing-Hang Zhang, Andrew Cossey, Jie Tong
Periprosthetic bone strain distributions in some of the typical cases of total knee replacement (TKR) were studied with regard to the selection of material, design and the alignments of tibial components to examine which conditions are more forgiving than the others to stress shielding post a TKR. Four tibial components with two implant designs (cruciate sacrificing and cruciate retaining) and material properties (metal-backed (MB) and all-polyethylene (AP)) were considered in a specimen-specific finite element tibia bone model loaded in a neutral position...
October 10, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/27739555/evaluation-of-the-relationship-of-tibiofemoral-kinematics-before-and-after-total-knee-replacement-in-an-in-vitro-model-of-cranial-cruciate-deficiency-in-the-dog
#13
Rebecca N Howie, Timothy L Foutz, Curtis C Cathcart, Jeff S Burmeister, Steve C Budsberg
OBJECTIVE: To investigate the relationship between tibiofemoral kinematics before and after total knee replacement (TKR) in vitro. ANIMALS: Eight canine hemipelves. METHODS: A modified Oxford Knee Rig was used to place cadaveric limbs through a range of passive motion allowing the kinematics of the stifle to be evaluated. Four measurements were performed: a control stage, followed by a cranial cruciate transection stage, then following TKR with the musculature intact stage, and finally TKR with removal of limb musculature stage...
October 14, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27704332/a-cost-utility-analysis-of-dabigatran-enoxaparin-and-usual-care-for-venous-thromboprophylaxis-after-hip-or-knee-replacement-surgery-in-thailand
#14
Surachai Kotirum, Bunchai Chongmelaxme, Nathorn Chaiyakunapruk
To analyze the cost-utility of oral dabigatran etexilate, enoxaparin sodium injection, and no intervention for venous thromboembolism (VTE) prophylaxis after total hip or knee replacement (THR/TKR) surgery among Thai patients. A cost-utility analysis using a decision tree model was conducted using societal and healthcare payers' perspectives to simulate relevant costs and health outcomes covering a 3-month time horizon. Costs were adjusted to year 2014. The willingness-to-pay threshold of THB 160,000 (USD 4926) was used...
October 4, 2016: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/27698080/tyrosine-kinase-receptor-expression-in-canine-liposarcoma
#15
G Avallone, V Pellegrino, P Roccabianca, E Lepri, L Crippa, G Beha, L De Tolla, G Sarli
The expression of tyrosine kinase receptors is attracting major interest in human and veterinary oncological pathology because of their role as targets for adjuvant therapies. Little is known about tyrosine kinase receptor (TKR) expression in canine liposarcoma (LP), a soft tissue sarcoma. The aim of this study was to evaluate the immunohistochemical expression of the TKRs fibroblast growth factor receptor 1 (FGFR1) and platelet-derived growth factor receptor-β (PDGFRβ); their ligands, fibroblast growth factor 2 (FGF2) and platelet-derived growth factor B (PDGFB); and c-kit in canine LP...
October 3, 2016: Veterinary Pathology
https://www.readbyqxmd.com/read/27672575/compartment-syndrome-following-total-knee-replacement-a-case-report-and-literature-review
#16
Mohammed Shaath, Mohamed Sukeik, Saadallah Mortada, Sean Masterson
Compartment syndrome is a rare complication of total knee replacement (TKR) surgery that needs prompt diagnosis and treatment as it may be associated with high morbidity and mortality. We have found very few reports in the literature describing compartment syndrome after TKRs and therefore, present a relevant case which occurred in the immediate postoperative phase and was treated with fasciotomy and subsequent operations to close the soft tissue defects.
September 18, 2016: World Journal of Orthopedics
https://www.readbyqxmd.com/read/27648327/resection-and-resolution-of-bone-marrow-lesions-associated-with-an-improvement-of-pain-after-total-knee-replacement-a-novel-case-study-using-a-3-tesla-metal-artefact-reduction-mri-sequence
#17
Thomas Kurien, Robert Kerslake, Brett Haywood, Richard G Pearson, Brigitte E Scammell
We present our case report using a novel metal artefact reduction magnetic resonance imaging (MRI) sequence to observe resolution of subchondral bone marrow lesions (BMLs), which are strongly associated with pain, in a patient after total knee replacement surgery. Large BMLs were seen preoperatively on the 3-Tesla MRI scans in a patient with severe end stage OA awaiting total knee replacement surgery. Twelve months after surgery, using a novel metal artefact reduction MRI sequence, we were able to visualize the bone-prosthesis interface and found complete resection and resolution of these BMLs...
2016: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/27647443/effect-of-body-mass-index-on-knee-function-outcomes-following-continuous-passive-motion-in-patients-with-osteoarthritis-after-total-knee-replacement-a-retrospective-study
#18
C-D Liao, Y-C Huang, Y-S Chiu, T-H Liou
OBJECTIVE: Obesity may influence postoperative rehabilitation outcomes after total knee replacement (TKR). The aim of this study was to evaluate the effects of body mass index (BMI) on the progression of inpatient rehabilitation using continuous passive motion (CPM) and its treatment outcomes. PARTICIPANTS AND SETTING: A retrospective study was conducted in a rehabilitation centre. In total, 354 patients undergoing primary TKR were enrolled through medical chart review...
May 9, 2016: Physiotherapy
https://www.readbyqxmd.com/read/27636123/relationship-between-knee-pain-and-patient-preferences-for-joint-replacement-healthcare-access-matters
#19
Ernest R Vina, Di Ran, Erin L Ashbeck, Manjinder Kaur, C Kent Kwoh
OBJECTIVES: Determine if severity of osteoarthritis-related knee pain is associated with willingness to undergo total knee replacement (TKR) and if this association is confounded or modified by components of socioeconomic status and healthcare coverage. METHODS: Cross-sectional analysis was conducted among 3530 Osteoarthritis Initiative study participants. Logistic regression models were used to assess the effect of knee pain severity (0: none, 1-3: mild, 4-7: moderate, 8-10: severe) on willingness to undergo TKR...
September 16, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27631237/complications-after-total-knee-replacement-in-patients-with-chronic-obstructive-pulmonary-disease-a-nationwide-case-control-study
#20
Kuang-Ming Liao, Hsueh-Yi Lu
The incidence and prevalence of chronic obstructive pulmonary disease (COPD) is associated with increasing age. Osteoarthritis is also a growing problem in the aging population, and total knee replacement (TKR) is a common surgical procedure for this population. An increasing number of COPD patients are receiving TKR, but few studies have examined the complications and outcomes after TKR in COPD patients. The purpose of this study was to investigate the complications, including mortality, wound infections, hospitalization readmission, pneumonia (PN), and cerebrovascular accidents (CVAs) in patients with COPD after receiving TKR...
September 2016: Medicine (Baltimore)
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