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https://www.readbyqxmd.com/read/28323904/pyrrolidine-dithiocarbamate-administered-during-ex-vivo-lung-perfusion-promotes-rehabilitation-of-injured-donor-rat-lungs-obtained-after-prolonged-warm-ischemia
#1
Cyril Francioli, Xingyu Wang, Roumen Parapanov, Etienne Abdelnour, Jérôme Lugrin, Fabrizio Gronchi, Jean Perentes, Philippe Eckert, Hans-Beat Ris, Lise Piquilloud, Thorsten Krueger, Lucas Liaudet
Damaged lung grafts obtained after circulatory death (DCD lungs) and warm ischemia may be at high risk of reperfusion injury after transplantation. Such lungs could be pharmacologically reconditioned using ex-vivo lung perfusion (EVLP). Since acute inflammation related to the activation of nuclear factor kappaB (NF-κB) is instrumental in lung reperfusion injury, we hypothesized that DCD lungs might be treated during EVLP by pyrrolidine dithiocarbamate (PDTC), an inhibitor of NF-κB. Rat lungs exposed to 1h warm ischemia and 2 h cold ischemia were subjected to EVLP during 4h, in absence (CTRL group, N = 6) or in presence of PDTC (2...
2017: PloS One
https://www.readbyqxmd.com/read/28323322/adaptations-following-an-intermittent-hypoxia-hyperoxia-training-in-coronary-artery-disease-patients-a-controlled-study
#2
Oleg Glazachev, Phylipp Kopylov, Davide Susta, Elena Dudnik, Elena Zagaynaya
BACKGROUND: Repeated exposure to intermittent normobaric hypoxia improves exercise tolerance in cardiac patients. Little is known on the effects of intermittent normobaric hypoxia-hyperoxia exposure in coronary artery disease (CAD) patients (New York Heart Association II-III). HYPOTHESIS: IHHT improves exercise tolerance, cardiometabolic profile, and quality of life in CAD patients. METHODS: The study design was a nonrandomized, controlled, before-and-after trial...
March 21, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28322035/multidisciplinary-rehabilitation-program-after-breast-cancer-benefits-on-physical-function-anthropometry-and-quality-of-life
#3
Anne-France Leclerc, Marguerite Foidart-Dessalle, Marco Tomasella, Philippe Coucke, Martine Devos, Olivier Bruyère, Thierry Bury, Dorian Deflandre, Guy Jerusalem, Eric Lifrange, Jean-François Kaux, Jean-Michel Crielaard, Didier Maquet
BACKGROUND: Different clinical trials show beneficial effects of physical training offered during and / or after breast cancer treatment. However, given the variety of side effects that may be encountered, physical training could be combined with psychological, relational and social guidance. This kind of multidisciplinary program has been little studied so far. AIM: To determine the benefits of a three-month multidisciplinary rehabilitation program among women after breast cancer treatment...
March 20, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28319533/-perfscore-a-multidimensional-score-a-simple-way-to-predict-the-success-of-cardiac-rehabilitation
#4
Patrizia Maras, Sara Doimo, Alessando Altinier, Alessio Della Mattia, Luigia Scudeller, Gianfranco Sinagra, Catherine Klersy
BACKGROUND: We propose a simple and reliable score, performance score ('PERFSCORE'), that allows cardiologists to assess the achievement of therapeutic goals. METHODS: We identified six indicators of cardiac rehabilitation performance: heart rate (HR) less than 70 beats/min; blood pressure (BP) less than 140/90 mmHg; smoking cessation or non-smokers; left ventricular ejection fraction (LVEF) more than 40%; LDLc less than 100 mg/dl or more than 70 mg/dl if diabetic; and on treatment at least with three drugs among angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blocker (ARBs), β-blockers, statins, and ASA...
March 17, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28318815/the-role-of-cardiac-rehabilitation-in-patients-with-heart-disease
#5
REVIEW
Sean R McMahon, Philip A Ades, Paul D Thompson
Cardiac rehabilitation is a valuable treatment for patients with a broad spectrum of cardiac disease. Current guidelines support its use in patients after acute coronary syndrome, coronary artery bypass grafting, coronary stent placement, valve surgery, and stable chronic systolic heart failure. Its use in these conditions is supported by a robust body of research demonstrating improved clinical outcomes. Despite this evidence, cardiac rehabilitation referral and attendance remains low and interventions to increase its use need to be developed...
February 15, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28316572/eccentric-ergometer-training-promotes-locomotor-muscle-strength-but-not-mitochondrial-adaptation-in-patients-with-severe-chronic-obstructive-pulmonary-disease
#6
Norah J MacMillan, Sophia Kapchinsky, Yana Konokhova, Gilles Gouspillou, Riany de Sousa Sena, R Thomas Jagoe, Jacinthe Baril, Tamara E Carver, Ross E Andersen, Ruddy Richard, Hélène Perrault, Jean Bourbeau, Russell T Hepple, Tanja Taivassalo
Eccentric ergometer training (EET) is increasingly being proposed as a therapeutic strategy to improve skeletal muscle strength in various cardiorespiratory diseases, due to the principle that lengthening muscle actions lead to high force-generating capacity at low cardiopulmonary load. One clinical population that may particularly benefit from this strategy is chronic obstructive pulmonary disease (COPD), as ventilatory constraints and locomotor muscle dysfunction often limit efficacy of conventional exercise rehabilitation in patients with severe disease...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28303967/effects-of-exercise-based-cardiac-rehabilitation-in-patients-after-percutaneous-coronary-intervention-a-meta-analysis-of-randomized-controlled-trials
#7
Xinyu Yang, Yanda Li, Xiaomeng Ren, Xingjiang Xiong, Lijun Wu, Jie Li, Jie Wang, Yonghong Gao, Hongcai Shang, Yanwei Xing
In this study, we assessed the effect of rehabilitation exercise after percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD). We performed a meta-analysis to determine the effects of exercise in patients after PCI. The Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, the Embase database, China National Knowledge Internet (CNKI), China Biology Medicine (CBM), and the Wanfang Database were searched for randomized controlled trials (RCTs). The key words used for the searches were PCI, exercise, walking, jogging, Tai Chi, and yoga...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28302548/availability-use-and-barriers-to-cardiac-rehabilitation-in-lmic
#8
Loheetha Ragupathi, Judy Stribling, Yuliya Yakunina, Valentin Fuster, Mary Ann McLaughlin, Rajesh Vedanthan
BACKGROUND: Cardiac rehabilitation (CR) is a cornerstone of secondary prevention of ischemic heart disease. It is critically important in low- and middle-income countries (LMIC), where the burden of ischemic heart disease is substantial and growing. However, the availability and utilization of CR in LMIC is not systematically known. OBJECTIVES: This study sought to characterize the availability, use, and barriers to the use of CR. METHODS: Electronic databases (Cochrane Library, EMBASE, PubMed, Web of Science) were searched from January 1, 1980 to May 31, 2013 for articles on CR in LMIC...
March 13, 2017: Global Heart
https://www.readbyqxmd.com/read/28302117/the-effects-of-music-intervention-on-burn-patients-during-treatment-procedures-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#9
Jinyi Li, Liang Zhou, Yungui Wang
BACKGROUND: The treatment of burn patients is very challenging because burn injuries are one of the most severe traumas that can be experienced. The effect of music therapy on burn patients has been widely reported, but the results have been inconsistent. Thus, we performed a systematic review and meta-analysis of randomized controlled trials in burn patients to determine the effect of music during treatments. METHODS: We searched a variety of electronic databases, including MEDLINE (via PubMed), EMBASE, Cochrane Library, Psychinfo, VIP Database for Chinese Technical Periodicals (VIP) and China National Knowledge Infrastructure (CNKI) for relevant trials on the basis of predetermined eligibility criteria...
March 17, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28295468/the-protective-effects-of-a-novel-fitness-fatness-index-on-all-cause-mortality-among-adults-with-cardiovascular-disease
#10
Emily Frith, Paul D Loprinzi
BACKGROUND: We evaluated the specific association between a fitness-fatness index (FFI) and all-cause mortality among a national sample of US adults with coronary artery disease, congestive heart failure, or myocardial infarction. This FFI has recently emerged in the literature as a novel index of health. HYPOTHESIS: We hypothesize that FFI will be inversely associated with mortality risk. METHODS: The FFI was calculated as cardiorespiratory fitness divided by waist-to-height ratio...
March 10, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28295269/role-and-value-of-clinical-pharmacy-in-heart-failure-management
#11
Wendy Gattis Stough, J Herbert Patterson
Effectively managing heart failure requires a multi-disciplinary, holistic approach attuned to many factors: diagnosis of structural and functional cardiac abnormalities; medication, device, or surgical management; concomitant treatment of comorbidities; physical rehabilitation; dietary considerations; and social factors. This practice paper highlights the pharmacist's role in the management of patients with heart failure, the evidence supporting their functions, and steps to ensure the pharmacist resource is available to the broad population of patients with heart failure...
March 15, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28294880/-results-of-monitoring-of-the-plan-of-measures-directed-to-reduction-of-ischemic-heart-disease-in-north-caucasus-republics-analysis-of-dynamics-of-cardio-vascular-mortality
#12
M N Mamedov
Comparative analysis of dynamics of cardiovascular mortality in Russia and foreign countries as well as main directions of development of cardiological service in Russia are presented in this review article. Plan of measures for reduction of mortality from ischemic heart disease (IHD) was created in 2015. This plan comprises 4 blocks of assessment of the following measures: directed at improvement of primary IHD prevention (1), directed at secondary prevention of complications of IHD (2); directed at improvement of efficacy of medical care of patients with IHD (3), and directed at monitoring of some demographic parameters (4)...
May 2016: Kardiologiia
https://www.readbyqxmd.com/read/28290884/-the-new-european-questionnaire-for-assessment-of-quality-of-life-of-patients-with-ischemic-heart-disease-heartqol
#13
N V Pogosova, I H Boycharov, O Yu Sokolova, V A Vygodin
Quality of life (QL) of patients with ischemic heart disease (IHD) is a combination symptoms of the disease, physical state, emotional status, and social-laboring functioning. Until recently there were no universal questionnaire allowing to perform comparative analysis of QL of patients with effort angina (EF), survivors of myocardial infarction (MI) and chronic heart failure (CHF). Therefore, European Association of Cardiovascular Prevention and Rehabilitation conducted a study with the aim of developing universal questionnaire for assessment of QL in patients with IHD - HeartQol...
August 2016: Kardiologiia
https://www.readbyqxmd.com/read/28290875/-clinical-and-economic-aspects-of-meldonium-as-part-of-physical-rehabilitation-programs-in-patients-with-coronary-heart-disease-after-percutaneous-coronary-interventions
#14
N P Lyamina, I B Razborov, E S Karpov
PURPOSE: to analyze clinical and economical effectiveness of meldonium as component of integrated program of cardio-rehabilitation in patients with ischemic heart disease (IHD) in the early period after percutaneous coronary intervention (PCI) with incomplete revascularization. MATERIAL AND METHODS: A program of controlled physical training (CPT) was carried out in patients with stable IHD and positive post PCI exercise test (n=48, age less or equal 65 years) starting 8-10 days after PCI...
August 2016: Kardiologiia
https://www.readbyqxmd.com/read/28290855/-problems-of-determination-of-degree-of-disability-after-coronary-artery-bypass-surgery
#15
O L Barbarash, I V Samorodskaya, L A Efros, S A Pomeshkina, N V Kondrikova, S A Boitsov
The review contains data on rates of permanent loss of working ability (disability) after coronary artery bypass grafting (CABG) in Russia and in European populations of patients with ischemic heart disease. According to domestic studies determination of disability status is not based on assessment of objective characteristics of functional reserve of cardiovascular system. Most patients after surgery retain disability status. CABG is not a rehabilitating factor but on the contrary results in increase of number of officially disabled people...
June 2016: Kardiologiia
https://www.readbyqxmd.com/read/28289645/accuracy-of-heart-rate-measurement-using-smartphones-during-treadmill-exercise-in-male-patients-with-ischemic-heart-disease
#16
Eun Sun Lee, Jin Seok Lee, Min Cheol Joo, Ji Hee Kim, Se Eung Noh
OBJECTIVE: To evaluate the accuracy of a smartphone application measuring heart rates (HRs), during an exercise and discussed clinical potential of the smartphone application for cardiac rehabilitation exercise programs. METHODS: Patients with heart disease (14 with myocardial infarction, 2 with angina pectoris) were recruited. Exercise protocol was comprised of a resting stage, Bruce stage II, Bruce stage III, and a recovery stage. To measure HR, subjects held smartphone in their hands and put the tip of their index finger on the built-in camera for 1 minute at each exercise stage such as resting stage, Bruce stage II, Bruce stage III, and recovery stage...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28289644/quality-of-life-and-physical-ability-changes-after-hospital-based-cardiac-rehabilitation-in-patients-with-myocardial-infarction
#17
Byung Joo Lee, Jin Young Go, Ae Ryung Kim, Seong Min Chun, Minhyuk Park, Dong Heon Yang, Hun Sik Park, Tae-Du Jung
OBJECTIVE: To evaluate the effect of hospital-based cardiac rehabilitation (CR) on quality of life (QOL) and physical ability in patients with myocardial infarction (MI). METHODS: Patients with MI who were referred to the Cardiac Health and Rehabilitation Center 2 weeks after percutaneous coronary intervention were divided into CR and non-CR groups. The CR group performed supervised exercises 3 times a week for 2 months. QOL assessment, using the 36-item Short-Form Health Survey (SF-36) and physical ability evaluation were performed at the beginning and end of CR...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28285121/a-novel-rehabilitation-intervention-for%C3%A2-older-patients-with-acute-decompensated%C3%A2-heart-failure-the-rehab-hf-pilot-study
#18
Gordon R Reeves, David J Whellan, Christopher M O'Connor, Pamela Duncan, Joel D Eggebeen, Timothy M Morgan, Leigh Ann Hewston, Amy Pastva, Mahesh J Patel, Dalane W Kitzman
OBJECTIVES: This study sought to assess a novel physical rehabilitation intervention in older patients hospitalized for acute decompensated heart failure (ADHF). BACKGROUND: After ADHF, older patients, who are frequently frail with multiple comorbidities, have prolonged and incomplete recovery of physical function and remain at high risk for poor outcomes. METHODS: The REHAB-HF (Rehabilitation Therapy in Older Acute Heart Failure Patients) pilot study was a 3-site, randomized, attention-controlled pilot study of a tailored, progressive, multidomain physical rehabilitation intervention beginning in the hospital and continuing for 12 weeks post-discharge in patients ≥60 years hospitalized with ADHF...
March 5, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28270895/significance-of-cardiac-rehabilitation-on-visit-to-visit-variability-of-blood-pressure-in-patients-with-cardiovascular-disease-in-a-12-month-follow-up
#19
Toshihisa Ishida, Shin-Ichiro Miura, Kanta Fujimi, Makito Futami, Yoko Ueda, Takashi Ueda, Tadaaki Arimura, Rie Koyoshi, Yuhei Shiga, Ken Kitajima, Keijiro Saku
BACKGROUND: Visit-to-visit variability (VVV) in blood pressure (BP) has been shown to be a strong predictor of cardiovascular disease (CVD). However, the long-term effect of comprehensive cardiac rehabilitation (CR) with exercise training on VVV in BP has not yet been established. Therefore, we evaluated the long-term effects of CR on VVV in BP in patients with CVD. METHODS: Twenty-two CVD patients in a 12-month CR program who had at least six clinic visits per month to measure BP were enrolled...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28268383/mobileheart-a-mobile-smartphone-based-application-that-supports-and-monitors-coronary-artery-disease-patients-during-rehabilitation
#20
I Frederix, S Sankaran, K Coninx, P Dendale
Conventional center-based cardiac rehabilitation adherence is poor, adversely affecting long-term efficacy. Innovative strategies such as telerehabilitation are perceived as promising alternatives to improve care delivery. This paper presents the results of prior and ongoing work on the design and development of MobileHeart, a telemedical smartphone-based application to be used in secondary prevention for ischemic heart disease patients. Its constituent components are discussed separately, the minimal necessary cardiovascular monitoring requirements are elaborated in more detail...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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