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https://www.readbyqxmd.com/read/29134581/the-pain-of-ambivalence-over-emotional-expression
#1
Carol Wang, Celia C Y Wong, Qian Lu
PURPOSE: Ambivalence over emotional expression (AEE) is defined as the desire to express emotion but failing to do so. Recent studies have revealed that AEE is associated with more pain. Pain is common among cancer survivors. This cross-sectional study investigated the association between AEE and pain, its underlying mechanism, and cultural relevance among cancer survivors. METHODS: Ninety-six Chinese American breast cancer survivors completed a questionnaire package assessing AEE and pain...
November 13, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29131058/nonfunctional-redundant-acts-characterize-ocd-even-in-ocd-unrelated-tasks-a-demonstration-in-questionnaire-completion
#2
Maya Amitai, Nitzan Arnon, Noa Shaham, Shay Gur, Alan Apter, Abraham Weizman, Haggai Hermesh
BACKGROUND: Ethological methods used to analyze human obsessive-compulsive disorder (OCD) rituals demonstrated excess of unnecessary repetitions as well as irrelevant, idiosyncratic acts (additions) compared to normal activity. A question that still remains is whether these well-known repetitions and additions are manifested in behaviors unrelated to the OCD rituals. Our objectives were to: (1) assess whether OCD-related repetitions and additions as found in previous studies also affect the patients' activity of filling out questionnaires and (2) evaluate the specificity of these behaviors to OCD as opposed to other anxiety disorders and healthy controls...
November 3, 2017: Psychopathology
https://www.readbyqxmd.com/read/29107201/alexithymia-and-problematic-alcohol-use-a-critical-update
#3
REVIEW
K E Cruise, R Becerra
There has been a substantial growth in empirical research aimed at examining the co-occurrence of alexithymia and problematic alcohol use and alcohol use disorder (AUD) since Thorberg, Young, Sullivan, and Lyvers (2009) original review article. The objective of the present paper is therefore to provide a critical update review of research on alexithymia and problematic alcohol use published since 2009. A systematic search was conducted through PsychINFO, Medline, and ProQuest databases to obtain relevant literature published between 2009 and 2016...
October 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29101315/hippocampal-gaba-enables-inhibitory-control-over-unwanted-thoughts
#4
Taylor W Schmitz, Marta M Correia, Catarina S Ferreira, Andrew P Prescot, Michael C Anderson
Intrusive memories, images, and hallucinations are hallmark symptoms of psychiatric disorders. Although often attributed to deficient inhibitory control by the prefrontal cortex, difficulty in controlling intrusive thoughts is also associated with hippocampal hyperactivity, arising from dysfunctional GABAergic interneurons. How hippocampal GABA contributes to stopping unwanted thoughts is unknown. Here we show that GABAergic inhibition of hippocampal retrieval activity forms a key link in a fronto-hippocampal inhibitory control pathway underlying thought suppression...
November 3, 2017: Nature Communications
https://www.readbyqxmd.com/read/29056983/glutamate-genetics-in-obsessive-compulsive-disorder-a-review
#5
Rageen Rajendram, Sefi Kronenberg, Christie L Burton, Paul D Arnold
OBJECTIVE: Obsessive-compulsive disorder (OCD) is common and debilitating with patients exhibiting persistent intrusive thoughts (obsessions), repetitive ritualistic behaviours (compulsions) and anxiety. While it is known that OCD is highly heritable, the specific genetic risk factors for OCD are still largely unknown. The etiology of OCD has also not been fully elucidated but there is growing evidence that glutamate signaling dysfunction in the cortico-striatal-thalamo-cortical (CSTC) circuitry plays a role in its pathogenesis...
2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29042551/integrating-evolutionary-and-regulatory-information-with-a-multispecies-approach-implicates-genes-and-pathways-in-obsessive-compulsive-disorder
#6
Hyun Ji Noh, Ruqi Tang, Jason Flannick, Colm O'Dushlaine, Ross Swofford, Daniel Howrigan, Diane P Genereux, Jeremy Johnson, Gerard van Grootheest, Edna Grünblatt, Erik Andersson, Diana R Djurfeldt, Paresh D Patel, Michele Koltookian, Christina M Hultman, Michele T Pato, Carlos N Pato, Steven A Rasmussen, Michael A Jenike, Gregory L Hanna, S Evelyn Stewart, James A Knowles, Stephan Ruhrmann, Hans-Jörgen Grabe, Michael Wagner, Christian Rück, Carol A Mathews, Susanne Walitza, Daniëlle C Cath, Guoping Feng, Elinor K Karlsson, Kerstin Lindblad-Toh
Obsessive-compulsive disorder is a severe psychiatric disorder linked to abnormalities in glutamate signaling and the cortico-striatal circuit. We sequenced coding and regulatory elements for 608 genes potentially involved in obsessive-compulsive disorder in human, dog, and mouse. Using a new method that prioritizes likely functional variants, we compared 592 cases to 560 controls and found four strongly associated genes, validated in a larger cohort. NRXN1 and HTR2A are enriched for coding variants altering postsynaptic protein-binding domains...
October 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29038689/making-connections-exploring-the-centrality-of-posttraumatic-stress-symptoms-and-covariates-after-a-terrorist-attack
#7
Marianne Skogbrott Birkeland, Trond Heir
Background: Posttraumatic stress symptoms are interconnected. Knowledge about which symptoms of posttraumatic stress are more strongly interconnected or central than others may have implications for the targeting of clinical interventions. Exploring whether symptoms of posttraumatic stress may be differentially related to covariates can contribute to our knowledge on how posttraumatic stress symptoms arise and are maintained. Objective: This study aimed to identify the most central symptoms of posttraumatic stress and their interconnections, and to explore how covariates such as exposure, sex, neuroticism, and social support are related to the network of symptoms of posttraumatic stress...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29024232/social-constraints-and-psychological-well-being-after-prostate-cancer-a-follow-up-at-12-and-24-months-after-surgery
#8
Karin Stinesen Kollberg, Thordis Thorsteinsdottir, Ulrica Wilderäng, Jonas Hugosson, Peter Wiklund, Anders Bjartell, Stefan Carlsson, Johan Stranne, Eva Haglind, Gunnar Steineck
OBJECTIVE: Studies indicate that social constraints (barriers to emotional expression) may be a risk factor for psychological morbidity. We aimed to investigate the association between prostate cancer- related social constraints and psychological well-being following prostate cancer surgery. METHODS: In a group of 3478 partnered patients, participating in the Laparoscopic Prostatectomy Robot Open (LAPPRO) trial, a prospective multicenter comparative study of robot-assisted laparoscopic and retropubic radical prostatectomy for prostate cancer, we used log-binomial regression analysis to investigate the links between prostate cancer-related social constraints at 3 months after surgery and psychological well-being at 12 and 24 months...
October 12, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28992533/neural-correlates-of-affective-and-non-affective-cognition-in-obsessive-compulsive-disorder-a-meta-analysis-of-functional-imaging-studies
#9
A Rasgon, W H Lee, E Leibu, A Laird, D Glahn, W Goodman, S Frangou
Obsessive compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive ritualistic behaviors and has been associated with diverse functional brain abnormalities. We sought to synthesize current evidence from functional magnetic resonance imaging (fMRI) studies and examine their alignment to pathogenetic models of OCD. Following systematic review, we identified 54 task-fMRI studies published in the last decade comparing adults with OCD (n=1186) to healthy adults (n=1159) using tasks of affective and non-affective cognition...
September 1, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28959383/a-new-short-version-of-the-posttraumatic-diagnostic-scale-validity-among-japanese-adults-with-and-without-ptsd
#10
Mariko Itoh, Yuri Ujiie, Nobukazu Nagae, Madoka Niwa, Toshiko Kamo, Mingming Lin, Sayuri Hirohata, Yoshiharu Kim
Background: Identifying high-risk groups for posttraumatic stress disorder (PTSD) during evacuation situations requires a valid short screening tool. The re-experiencing symptoms of PTSD are considered helpful for distinguishing those with PTSD from those without, as they are thought to be specific to PTSD, have less ambiguity for respondents, and are representative of all PTSD symptoms. Objective: To develop a new short version of the Posttraumatic Diagnostic Scale (PDS) comprising only re-experiencing symptom items...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28913686/pretreatment-quality-of-life-in-patients-with-rectal-cancer-is-associated-with-intrusive-thoughts-and-sense-of-coherence
#11
Dan Asplund, Thue Bisgaard, David Bock, Jakob Burcharth, Elisabeth González, Eva Haglind, Yanislav Kolev, Peter Matthiessen, Carina Rosander, Jacob Rosenberg, Kenneth Smedh, Marina Åkerblom Sörensson, Eva Angenete
PURPOSE: Quality of life may predict survival. In addition to clinical variables, it may be influenced by psychological factors, some of which may be accessible for intervention. The primary objective of this study was to investigate the association of intrusive thoughts and the patients' sense of coherence with pretreatment quality of life in patients with newly diagnosed rectal cancer. METHODS: Patients were prospectively included in 16 hospitals in Sweden and Denmark...
November 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28901577/suppression-mediates-the-effect-of-5-httlpr-by-stress-interaction-on%C3%A2-depression
#12
Gennady G Knyazev, Daria V Bazovkina, Alexander N Savostyanov, Vladimir S Naumenko, Valeriya B Kuznetsova, Ekaterina A Proshina
A number of studies have shown that the presence of short (S), as opposed to long (L), allele of the serotonin transporter-linked polymorphic region (5-HTTLPR) is associated with a higher risk for depression following exposure to stressful life events. However, many other studies failed to confirm this association. One reason for this inconsistency might be the fact that the interaction of the 5-HTTLPR polymorphism with stress may relate not to depression per se, but rather to adaptive or maladaptive emotion regulation strategies...
October 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28865371/the-relationship-between-cognitions-and-symptoms-in-obsessive-compulsive-disorder
#13
Lee Tibi, Patricia van Oppen, Anton J L M van Balkom, Merijn Eikelenboom, Gert-Jan Hendriks, Gideon E Anholt
BACKGROUND: The cognitive theory of obsessive-compulsive disorder (OCD) ascertains that catastrophic (mis)interpretations of normally occurring intrusive thoughts are related to the maintenance of OCD. Nonetheless, findings supporting the relationship between cognitive biases and OCD symptoms are largely inconsistent. In the present study we examined the relationship between OCD cognitions and symptoms among 382 OCD patients participating in the longitudinal Netherlands Obsessive Compulsive Disorder Association (NOCDA) study...
January 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28822003/pedophilia-themed-obsessive-compulsive-disorder-assessment-differential-diagnosis-and-treatment-with-exposure-and-response-prevention
#14
Simone Leavell Bruce, Terence H W Ching, Monnica T Williams
Fears of sexually harming children are fairly common among clients suffering from obsessive-compulsive disorder (OCD), yet these symptoms are largely unrecognized and frequently misdiagnosed by mental health professionals. Specifically, clients with pedophilia-themed OCD (P-OCD) experience excessive worries and distressing intrusive thoughts about being sexually attracted to, and sexually violating, children. Expressing these concerns may provoke misjudgments from uninformed mental health professionals that a client is presenting instead with pedophilic disorder...
August 18, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28821746/neural-circuitry-governing-anxious-individuals-mis-allocation-of-working-memory-to-threat
#15
Daniel M Stout, Alexander J Shackman, Walker S Pedersen, Tara A Miskovich, Christine L Larson
Dispositional anxiety is a trait-like phenotype that confers increased risk for a range of debilitating neuropsychiatric disorders. Like many patients with anxiety disorders, individuals with elevated levels of dispositional anxiety are prone to intrusive and distressing thoughts in the absence of immediate threat. Recent electrophysiological research suggests that these symptoms are rooted in the mis-allocation of working memory (WM) resources to threat-related information. Here, functional MRI was used to identify the network of brain regions that support WM for faces and to quantify the allocation of neural resources to threat-related distracters in 81 young adults...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811021/quantitative-analysis-of-major-and-trace-elements-in-nh4hf2-modified-silicate-rock-powders-by-laser-ablation-inductively-coupled-plasma-mass-spectrometry
#16
Wen Zhang, Zhaochu Hu, Yongsheng Liu, Wenwu Yang, Haihong Chen, Shenghong Hu, Hongyan Xiao
In this paper, we described a NH4HF2 digestion method as sample preparation for the rapid determination of major and trace elements in silicate rocks using laser ablation-inductively coupled plasma mass spectrometry (LA-ICP-MS). Sample powders digested by NH4HF2 at 230 °C for 3 h form ultrafine powders with a typical grain size d80 < 8.5 μm, and various silicate rocks have a consistent grain morphology and size, allowing us to produce pressed powder pellets that have excellent cohesion and homogeneity suitable for laser ablation micro-analysis without the addition of binder...
August 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28796737/strength-of-occipital-hair-as-an-explanation-for-pilonidal-sinus-disease-caused-by-intruding-hair
#17
Dietrich Doll, Friederike D Bosche, Verena K Stauffer, Inga Sinicina, Sebastian Hoffmann, Dominic van der Zypen, Markus M Luedi
BACKGROUND: Pilonidal sinus disease is thought to be caused by intrusion of hair into healthy skin; loose hair in the intergluteal fold is thought to promote disease. However, compelling evidence to support these postulates is lacking; the cause of pilonidal sinus disease remains uncertain. OBJECTIVE: To determine whether particular properties of hair are associated with susceptibility to pilonidal sinus disease, we compared physical properties of hairs of patients with pilonidal sinus disease with hairs from control subjects who were matched for sex, BMI, and age...
September 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28777877/timely-access-to-care-in-the-treatment-of-rectal-cancer-and-the-effect-on-quality-of-life
#18
Sofie Walming, Mattias Block, David Bock, Eva Angenete
AIM: The aim of this study was to investigate if a delay in a patient's first contact with a health care professional, and any subsequent delay in diagnosis, affected self-assessed quality of life prior to start of treatment for rectal cancer. METHOD: Questionnaires were administered when the patients had been informed of the diagnosis and planned treatment. The primary endpoint was self-assessed quality of life according to a seven-point Likert scale. The response variables were dichotomized and analysed by unadjusted and adjusted binary logistic regression...
August 4, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28776482/procrastination-as-a-self-regulation-failure-the-role-of-impulsivity-and-intrusive-thoughts
#19
Marie My Lien Rebetez, Lucien Rochat, Catherine Barsics, Martial Van der Linden
Procrastination has been described as the quintessence of self-regulatory failure. This study examines the relationships between this self-regulatory failure and other manifestations of self-regulation problems, namely impulsivity and intrusive thoughts. One hundred and forty-one participants completed questionnaires assessing procrastination, impulsivity (in particular, the urgency and lack of perseverance dimensions), and intrusive thoughts (i.e., rumination and daydreaming). Main results show that urgency mediated the association between rumination and procrastination, whereas rumination did not mediate the relation between urgency and procrastination...
January 1, 2017: Psychological Reports
https://www.readbyqxmd.com/read/28751351/intrusive-thoughts-and-images-of-intentional-harm-to-infants-in-the-context-of-maternal-postnatal-depression-anxiety-and-ocd
#20
Peter J Lawrence, Michelle G Craske, Claire Kempton, Anne Stewart, Alan Stein
No abstract text is available yet for this article.
August 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
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