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https://www.readbyqxmd.com/read/29031233/forensic-and-clinical-significance-of-serum-amylase-lipase-and-gamma-glutamyl-transferase-as-predictors-of-outcome-in-head-injured-patients
#1
Mona Mohamed Abo El-Noor, Naema Mahmoud ElHosary, Hytham Ibrahim Elatrozy, Hussein Mohamed Abou Elgheit, Ahmed Mohamed Elbelkasy, Ahmed Gamal Fath, Ghada Hamed El-Shafy
Head trauma is one of the leading causes of death and disability worldwide. Combined head lesions consist of more than one form of lesions. Biochemical markers of brain injury are used in determining the extent of brain injury and predicting its outcomes. The aim of this study was to investigate the forensic and clinical significance of serum amylase, lipase and gamma glutamyl transferase (GGT) as predictors of the outcome in head injured patients. PATIENTS AND METHODS: Sixty head injured patients were enrolled and subjected to personal history taking, general and local physical examination...
October 4, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29031193/the-retention-of-lacosamide-in-patients-with-epilepsy-and-intellectual-disability-in-three-specialised-institutions
#2
J Brenner, H J M Majoie, S van Beek, J A Carpay
PURPOSE: We describe the effectiveness of lacosamide as adjunctive therapy in patients with epilepsy and an intellectual disability. This information is relevant, as few data exist pertaining to this population with a high prevalence of (intractable) epilepsy. METHODS: We performed a retrospective study in three specialised institutions. Inclusion criteria were (1) focal onset or symptomatic generalized (2) therapy-resistant epilepsy, (3) intellectual disability and (4) residence in a care-facility for people with intellectual disabilities (PWID)...
October 3, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29031102/identifying-the-loss-of-functional-independence-of-older-people-residing-in-the-community-validation-of-the-prisma-7-instrument-in-brazil
#3
Ana Luiza Flores Saenger, Célia Pereira Caldas, Michel Raîche, Luciana Branco da Motta
The identification of the older people who are functionally dependant is essential for planning interventions with emphasis on secondary and tertiary prevention. Therefore, a simplified tool, able to identify these individuals for a more comprehensive evaluation, is required. However, the use of a measuring tool in a different socio-cultural context requires prior adaptation. This article aims to verify the psychometric properties of the PRISMA-7 in Brazilian context. This instrument was previously shown as able to identify older persons living in the community who have risk of functional loss in a Canadian study...
October 7, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29029293/multiple-chronic-conditions-in-spousal-caregivers-of-older-adults-with-functional-disability-associations-with-caregiving-difficulties-and-gains
#4
Courtney A Polenick, Amanda N Leggett, Noah J Webster, Benjamin H Han, Steven H Zarit, John D Piette
Objectives: Multiple chronic conditions (MCCs) are common and have harmful consequences in later life. Along with managing their own health, many aging adults care for an impaired partner. Spousal caregiving may be more stressful when caregivers have MCCs, particularly those involving complex management. Yet, little is known about combinations of conditions that are most consequential for caregiving outcomes. Method: Using a U.S. sample of 359 spousal caregivers and care recipients from the 2011 National Aging Trends Study and National Study of Caregiving, we examined three categories of MCCs based on similarity of management strategies (concordant only, discordant only, and both concordant and discordant) and their associations with caregiving difficulties and gains...
September 18, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29029214/sleepless-night-and-day-the-plight-of-progressive-supranuclear-palsy
#5
Christine M Walsh, Leslie Ruoff, Kathleen Walker, Alaisa Emery, Jonathan Varbel, Elissaios Karageorgiou, Phi N Luong, Irida Mance, Hilary W Heuer, Adam L Boxer, Lea T Grinberg, Joel H Kramer, Bruce L Miller, Thomas C Neylan
Objectives: To elucidate the unique sleep and waking characteristics in progressive supranuclear palsy (PSP), a neurodegenerative disease associated with motor deficits and dementia that largely affects the brainstem and thalamic regions. Methods: 20 PSP and 16 healthy older adult controls participated in this study. Participants underwent an overnight polysomnography and multiple sleep latency test (MSLT) the following day. Prior to the MSLT last trial, participants were asked to complete the Stanford Sleepiness Scale...
October 5, 2017: Sleep
https://www.readbyqxmd.com/read/29029213/recovery-kinetics-of-radiographic-and-implant-related-revision-patients-following-adult-spinal-deformity-surgery
#6
Peter G Passias, Cyrus M Jalai, Virginie Lafage, Gregory W Poorman, Shaleen Vira, Samantha R Horn, Justin K Scheer, D Kojo Hamilton, Breton G Line, Shay Bess, Frank J Schwab, Christopher P Ames, Douglas C Burton, Robert A Hart, Eric O Klineberg
BACKGROUND: Prior studies have observed similar health-related quality of life (HRQL) in revisions and nonrevision (NR) patients following adult spinal deformity (ASD) correction. However, a novel comparison approach may allow better comparisons in spine outcomes groups. OBJECTIVE: To determine if ASD revisions for radiographic and implant-related complications undergo a different recovery than NR patients. METHODS: Inclusion: ASD patients with complete HRQL (Oswestry Disability Index, Short-Form-36 version 2 (SF-36), Scoliosis Research Society [SRS]-22) at baseline, 6 wk, 1 yr, 2 yr...
October 6, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29029169/a-family-affair-family-typologies-of-problems-and-midlife-well-being
#7
Karen L Fingerman, Meng Huo, Jamie L Graham, Kyungmin Kim, Kira S Birditt
Background and Objectives: Midlife adults are a "pivot" generation, responding to parents' and grown children's problems. Yet, some midlife adults may have families where multiple members suffer sorrows, whereas other midlife adults may have families with few problems. This study examined: (a) typologies of problems across generations and (b) associations between profiles of problems and midlife adults' well-being. Research Design and Methods: Midlife adults (N = 633) reported their own, each parent's (n = 868), and grown child's (n = 1,785) physical (e...
September 23, 2017: Gerontologist
https://www.readbyqxmd.com/read/29029164/aging-parents-disabilities-and-daily-support-exchanges-with-middle-aged-children
#8
Meng Huo, Jamie L Graham, Kyungmin Kim, Steven H Zarit, Karen L Fingerman
Background and Objectives: Aging parents often incur disabilities in activities of daily living, which may limit their ability to give support and necessitate increased support from middle-aged children. Research has predominantly assessed disabled parents' retrospective reports of receiving support, but we know little about their daily support exchanges with middle-aged children. This study examined practical support, emotional support, and advice that aging parents with and without disabilities provided and received from middle-aged children, and links between these support exchanges and parents' daily mood...
September 23, 2017: Gerontologist
https://www.readbyqxmd.com/read/29029074/multimodality-imaging-evaluation-of-chagas-disease-an-expert-consensus-of-brazilian-cardiovascular-imaging-department-dic-and-the-european-association-of-cardiovascular-imaging-eacvi
#9
Maria Carmo P Nunes, Luigi Paolo Badano, J Antonio Marin-Neto, Thor Edvardsen, Covadonga Fernández-Golfín, Chiara Bucciarelli-Ducci, Bogdan A Popescu, Richard Underwood, Gilbert Habib, Jose Luis Zamorano, Roberto Magalhães Saraiva, Ester Cerdeira Sabino, Fernando A Botoni, Márcia Melo Barbosa, Marcio Vinicius L Barros, Eduardo Falqueto, Marcus Vinicius Simões, André Schmidt, Carlos Eduardo Rochitte, Manoel Otávio Costa Rocha, Antonio Luiz Pinho Ribeiro, Patrizio Lancellotti
Aims: To develop a document by Brazilian Cardiovascular Imaging Department (DIC) and the European Association of Cardiovascular Imaging (EACVI) to review and summarize the most recent evidences about the non-invasive assessment of patients with Chagas disease, with the intent to set up a framework for standardized cardiovascular imaging to assess cardiovascular morphologic and functional disturbances, as well as to guide the subsequent process of clinical decision-making. Methods and results: Chagas disease remains one of the most prevalent infectious diseases in Latin America, and has become a health problem in non-endemic countries...
September 25, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29028957/long-term-mortality-and-disability-in-cryptococcal-meningitis-a-systematic-literature-review
#10
Estelle Pasquier, John Kunda, Pierre De Beaudrap, Angela Loyse, Elvis Temfack, Síle F Molloy, Thomas S Harrison, Olivier Lortholary
Cryptococcal meningitis (CM) is the primary cause of meningitis in HIV-infected adults and an emerging disease in HIV-seronegative individuals. No literature review has studied the long-term outcome of CM. We performed a systematic review on the long-term (≥3 months) impact of CM (C. neoformans and C. gattii) on mortality and disability in HIV-infected and non-HIV-infected adults. Though the quality of current evidence is limited, the long-term impact of CM on survival and disability appears to be high. One-year mortality ranged from 13% in an Australian non-HIV C...
October 4, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29028764/the-prognostic-value-of-mri-in-moderate-and-severe-traumatic-brain-injury-a-systematic-review-and-meta-analysis
#11
Hourmazd Haghbayan, Amélie Boutin, Mathieu Laflamme, François Lauzier, Michèle Shemilt, Lynne Moore, Ryan Zarychanski, Vincent Douville, Dean Fergusson, Alexis F Turgeon
OBJECTIVES: Traumatic brain injury is a major cause of death and disability, yet many predictors of outcome are not precise enough to guide initial clinical decision-making. Although increasingly used in the early phase following traumatic brain injury, the prognostic utility of MRI remains uncertain. We thus undertook a systematic review and meta-analysis of studies evaluating the predictive value of acute MRI lesion patterns for discriminating clinical outcome in traumatic brain injury...
October 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29028759/which-domains-of-the-odi-best-predict-change-in-physical-function-in-patients-after-surgery-for-degenerative-lumbar-spondylolisthesis
#12
Hamadi A Murphy, Eugene Warnick, Richard McGintee, Kristen Nicholson, Douglas A Hollern, Christie Stawicki, Daniel Tarazona, Gregory D Schroeder, Barrett I Woods, Mark F Kurd, Jeffrey A Rihn, Greg D Anderson, Christopher K Kepler, Alan S Hilibrand, Alexander R Vaccaro, Kris E Radcliff
STUDY DESIGN: Retrospective Review OBJECTIVE.: The purpose of this study is to determine the differential improvement of the various individual items of the ODI and to determine their relationship to other measures of HRQOL. SUMMARY OF BACKGROUND DATA: The oswestry disability index (ODI) is an easily scored, common, ten-item questionnaire about symptoms relevant to lumbar spine pathology. It is not clear if all of the items can be reliably applied to spine surgery...
October 12, 2017: Spine
https://www.readbyqxmd.com/read/29028682/current-and-projected-burden-of-disease-from-high-ambient-temperature-in-korea
#13
Soo Eun Chung, Hae-Kwan Cheong, Jae-Hyun Park, Jong-Hun Kim, Hyunjin Han
BACKGROUND: The objective of the present study was to estimate the current and projected burden of disease from high ambient temperature using population-based data sources of nationwide mortality and morbidity in Korea. METHODS: Disability-adjusted life years (DALY) were estimated using noninjury-related deaths, and cerebrovascular and cardiovascular diseases from recently released nationwide health and mortality databases. Years of life lost and years lost due to disability were measured based on the point prevalence and number of deaths during the study period...
October 2017: Epidemiology
https://www.readbyqxmd.com/read/29028520/socioeconomic-status-and-childhood-autism-a-population-based-study-in-china
#14
Ping He, Chao Guo, Zhenjie Wang, Gong Chen, Ning Li, Xiaoying Zheng
There is limited evidence on the association between socioeconomic status (SES) and autism in developing nations. The aim of this study was to examine this association among children aged 0-17 years in China. We obtained data from the Second National Sample Survey on Disability, and selected 616,940 children for analysis. Autism was ascertained according to the International Statistical Classification of Diseases, Tenth Revision. Multiple logistic regressions allowing for weights showed that children in middle-income and high-income families were less likely than their low-income peers to have autism, with an odds ratio of 0...
August 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29028437/stimulants-do-not-increase-the-risk-of-seizure-related-hospitalizations-in-children-with-epilepsy
#15
Xinyue Liu, Paul R Carney, Regina Bussing, Richard Segal, Linda B Cottler, Almut G Winterstein
OBJECTIVE: To evaluate the safety of stimulants in children with epilepsy. METHODS: In a retrospective cohort study based on Medicaid Analytic eXtract billing records from 26 U.S. states from 1999 to 2010, we identified incident stimulant use among children with epilepsy through outpatient encounter claims and pharmacy claims. We established a control group of nonusers and used frequency matching to generate index dates. We followed both cohorts for 12 months and calculated hazard ratios [HRs] of current and former use of stimulants versus no use on the outcome of seizure-related hospitalization using multivariate Cox proportional hazard models...
October 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29028419/an-innovative-educational-clinical-experience-promoting-geriatric-exercise
#16
Kenneth M Manning, Darien L McNeill, Sandro O Pinheiro, Mitchell T Heflin, Willy M Valencia, Cathy C Lee, Steven C Castle, Leslie Katzel, Jamie Giffuni, Miriam C Morey
Formal educational training in physical activity promotion is relatively sparse throughout the medical education system. We describe an innovative clinical experience in physical activity directed at medical clinicians on a geriatrics rotation. The experience consists of a single 2.5 hour session, in which learners are partnered with geriatric patients engaged in a formal supervised exercise program. The learners are guided through an evidence-based exercise regimen tailored to functional status. This experience provides learners with an opportunity to interact with geriatric patients outside the hospital environment to counterbalance the typical geriatric rotation in which geriatric patients are often seen in clinics or hospitals...
October 13, 2017: Gerontology & Geriatrics Education
https://www.readbyqxmd.com/read/29027682/comparative-study-of-abdominal-muscle-thickness-on-ultrasonography-in-healthy-adolescents-and-patients-with-low-back-pain
#17
Nahid Rahmani, Mohammad Ali Mohseni-Bandpei, Mahyar Salavati, Roshanak Vameghi, Iraj Abdollahi
OBJECTIVES: Low back pain (LBP) is a common musculoskeletal disorder among different age groups, including adolescents. The purpose of this study was to compare the abdominal muscle thickness between healthy adolescents and those with LBP. METHODS: One hundred sixty healthy high school adolescents and 80 high school adolescents with LBP participated in the study. All participants were asked to complete a demographic questionnaire and also a visual analog scale and the Oswestry Disability Questionnaire to evaluate the pain intensity and functional disability...
October 13, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29027640/the-utility-of-botulinum-toxin-a-in-the-repair-of-distal-biceps-tendon-ruptures
#18
L S Khalil, R A Keller, N Mehran, N E Marshall, K Okoroha, N B Frisch, S P DeSilva
PURPOSE: The purpose of our study is to report the outcomes and complications in patients who underwent distal biceps tendon repair with the use of Botulinum toxin A (BoNT-A) as an adjunct to surgery. METHODS: A retrospective review of 14 patients who underwent 15 distal biceps tendon repairs was performed. All repaired tendons had their correlating muscle bellies injected intraoperatively with a mixture of 100U of BoNT-A and 10 ml of normal saline. Each patient was evaluated for surgical and post-operative complications and followed with Disabilities of the Arm, Shoulder and Hand (DASH) Disability Scores...
October 13, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/29027356/relationship-between-neighbourhood-socioeconomic-status-and-venous-thromboembolism-results-from-a-population-based-study
#19
D Kort, N van Rein, F J M van der Meer, H W Vermaas, N Wiersma, S C Cannegieter, W M Lijfering
BACKGROUND: The association between socioeconomic status and arterial cardiovascular disease is well established. However, despite its high burden of disability-adjusted life years, little research has been done to determine whether socioeconomic status is associated with venous thromboembolism. OBJECTIVE: To determine if neighbourhood socioeconomic status is associated with venous thromboembolism in a population-based study from the Netherlands. METHODS: We identified all patients aged 15 years and older with a first event of venous thromboembolism from inhabitants who lived in the urban districts of The Hague, Leiden and Utrecht in the Netherlands in 2008-2012...
October 12, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29027297/factors-associated-with-ambulatory-care-sensitive-emergency-department-visits-for-south-carolina-medicaid-members-with-intellectual-disability
#20
S McDermott, J Royer, J R Mann, B S Armour
INTRODUCTION: Ambulatory care sensitive conditions (ACSCs) can be seen as failure of access or management in primary care settings. Identifying factors associated with ACSCs for individuals with an Intellectual Disability (ID) provide insight into potential interventions. METHOD: To assess the association between emergency department (ED) ACSC visits and a number of demographic and health characteristics of South Carolina Medicaid members with ID. A retrospective cohort of adults with ID was followed from 2001 to 2011...
October 13, 2017: Journal of Intellectual Disability Research: JIDR
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