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https://www.readbyqxmd.com/read/29224255/the-highest-mortality-rates-in-childhood-dilated-cardiomyopathy-occur-during-the-first-year-after-diagnosis
#1
Shalan Fadl, Håkan Wåhlander, Katja Fall, Yang Cao, Jan Sunnegårdh
AIM: The aim of the study was to assess the incidence, mortality and morbidity of dilated cardiomyopathy (DCM) and non-compaction of the left ventricle (LVNC) in Swedish children. METHODS: We reviewed hospital records of all children with dilated cardiomyopathy (DCM) or left ventricular non-compaction cardiomyopathy (LVNC) up to the age of 18 in the healthcare region of western Sweden from 1991 to 2015. RESULTS: In total, 69 cases (61% males) were identified...
December 9, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29188707/increasing-extracellular-free-fatty-acid-production-in-escherichia-coli-by-disrupting-membrane-transport-systems
#2
Kwang Soo Shin, Sung Kuk Lee
Transposon mutagenesis was used to identify three mutants of E. coli that exhibited increased free fatty acid (FFA) production, which resulted from the disruption of genes related to membrane transport. Deletion of envR, gusC, and mdlA individually in a recombinant E. coli strain resulted in 1.4-, 1.8-, and 1.2-fold increases in total FFA production, respectively. In particular, deletion of envR increased the percentage of extracellular FFA to 46%, compared with 29% for the control strain. Multiple deletion of envR, gusC, mdlA, ompF, and fadL had a synergistic effect on FFA production, resulting in high extracellular FFA production, comprising up to 50% of total FFA production...
November 30, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29188490/igg4-related-disease-of-the-appendix
#3
Fadl H Veerankutty, Suhail Saleem, Sidharth Chacko, Vipin I Sreekumar, Prasad Krishnan, Deepak Varma, Prakash Kurumboor
No abstract text is available yet for this article.
November 29, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29187950/assessment-of-methicillin-resistant-staphylococcus-aureus-detection-methods-analytical-comparative-study
#4
Omer Mohammed Ali Ibrahim, Naser Eldin Bilal, Omran Fadl Osman, Magzoub Abbas Magzoub
Introduction: The heterogeneous expression of methicillin resistance in Staphylococcus aureus (MRSA) affects the efficiency of tests available to detect it. The objective of this study was to assess four phenotypic tests used to detect MRSA. Methods: This is an analytical comparative study conducted among sudanese patients during period from May 2012 to July 2014, Staphylococcus aureus strains were isolated and identified by conventional methods, and then confirmed by PCR detection of coagulase gene...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29159577/core-curriculum-case-illustration-a-rare-case-of-an-isolated-fallopian-tube-torsion
#5
Nehal Mohamed Ibrahim Saloum, Hayley Wurtz Hunt, Shaimaa Abdelhassib Fadl
This is the 46th installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at: http://www.erad.org/page/CCIP_TOC .
November 21, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/29055128/a-generalized-outflow-boundary-condition-impedance-model-for-non-invasive-prediction-of-ischemia-in-diseased-coronary-arteries
#6
Iyad A Fayssal, Fadl Moukalled, Samir Alam, Hussain Isma'eel
This paper reports on a new boundary condition formulation to model the total coronary myocardial flow and impedance characteristics of the myocardial vascular bed for any specific patient when considered for non-invasive diagnosis of fractional flow reserve (FFR). The developed boundary condition model inherits an implicit representation of the downstream truncated vascular bed and is based on integrating patient-specific physiologic parameters that can be non-invasively extracted for each patient to account for blood flow demand to the myocardium at rest and hyperemic conditions...
October 21, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29045339/blood-pressure-response-to-renal-denervation-is-correlated-with-baseline-blood-pressure-variability-a-patient-level-meta-analysis
#7
Alexandre Persu, Daniel Gordin, Lotte Jacobs, Lutgarde Thijs, Michiel L Bots, Wilko Spiering, Atena Miroslawska, Jonas Spaak, Ján Rosa, Mark R de Jong, Elena Berra, Fadl Elmula M Fadl Elmula, Grégoire Wuerzner, Alison H M Taylor, Agnieszka Olszanecka, Danuta Czarnecka, Patrick B Mark, Michel Burnier, Jean Renkin, Sverre E Kjeldsen, Jiří Widimský, Arif Elvan, Thomas Kahan, Terje K Steigen, Peter J Blankestijn, Ilkka Tikkanen, Jan A Staessen
BACKGROUND: Sympathetic tone is one of the main determinants of blood pressure (BP) variability and treatment-resistant hypertension. The aim of our study was to assess changes in BP variability after renal denervation (RDN). In addition, on an exploratory basis, we investigated whether baseline BP variability predicted the BP changes after RDN. METHODS: We analyzed 24-h BP recordings obtained at baseline and 6 months after RDN in 167 treatment-resistant hypertension patients (40% women; age, 56...
October 16, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/29044501/authentication-of-surveillance-videos-detecting-frame-duplication-based-on-residual-frame
#8
Sondos M Fadl, Qi Han, Qiong Li
Nowadays, surveillance systems are used to control crimes. Therefore, the authenticity of digital video increases the accuracy of deciding to admit the digital video as legal evidence or not. Inter-frame duplication forgery is the most common type of video forgery methods. However, many existing methods have been proposed for detecting this type of forgery and these methods require high computational time and impractical. In this study, we propose an efficient inter-frame duplication detection algorithm based on standard deviation of residual frames...
October 16, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29034337/new-biomarkers-of-post-settlement-growth-in-the-sea-urchin-strongylocentrotus-purpuratus
#9
Alyaa Elsaid Abdelaziz Fadl, Magdy Elsayed Mahfouz, Mona Mabrouk Taha El-Gamal, Andreas Heyland
Some sea urchins, including the purple sea urchin Strongylocentrotus purpuratus, have been successfully used in aquaculture, but their slow growth and late reproduction are challenging to overcome when developing efficient aquaculture production techniques. S. purpuratus develops via an indirect life history that is characterized by a drastic settlement process at the end of a larval period that lasts for several weeks. During this transition, the bilateral larva is transformed into a pentaradial juvenile, which will start feeding and growing in the benthic habitat...
October 2017: Heliyon
https://www.readbyqxmd.com/read/28986135/impact-of-supplementation-of-semen-extender-with-antioxidants-on-the-quality-of-chilled-or-cryopreserved-arabian-stallion-spermatozoa
#10
sAbdelRaouf M Ghallab, Abdallah M Shahat, Aya M Fadl, Mohamed M Ayoub, Adel R Moawad
The aim of the present study was to evaluate the effects of supplementation of semen extender with various non-enzymatic antioxidants on the quality of cooled or cryopreserved Arabian stallion spermatozoa. Semen collected from four pure Arabian stallions was centrifuged at 600g for 15 min. Spermatozoa were then diluted in INRA-82 extender supplemented with bovine serum albumin (BSA; 0, 10, 15 and 20 mg/mL) or trehalose (0, 75, 100 and 150 mM) or zinc sulphate (0, 100, 150 and 200 μM). The diluted semen was then either cooled at 5 °C or cryopreserved in 0...
October 4, 2017: Cryobiology
https://www.readbyqxmd.com/read/28962805/management-of-traumatic-brain-injury-an-update
#11
REVIEW
Mohamed H Abou El Fadl, Kristine H O'Phelan
The care of patients with traumatic brain injury can be one of the most challenging and rewarding aspects of clinical neurocritical care. This article reviews the approach to unique aspects specific to the care of this patient population. These aspects include appropriate use of sedation and analgesia, and the principles and the clinical use of intracranial monitors. Common clinical challenges encountered in these patients are also discussed, including the treatment of intracranial hypertension, temperature management, and control of sympathetic hyperactivity...
November 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28846421/operando-spectroscopic-analysis-of-cop-films-electrocatalyzing-the-hydrogen-evolution-reaction
#12
Fadl H Saadi, Azhar I Carim, Walter S Drisdell, Sheraz Gul, Jack H Baricuatro, Junko Yano, Manuel P Soriaga, Nathan S Lewis
Transition metal phosphides exhibit high catalytic activity toward the electrochemical hydrogen-evolution reaction (HER) and resist chemical corrosion in acidic solutions. For example, an electrodeposited CoP catalyst exhibited an overpotential, η, of -η < 100 mV at a current density of -10 mA cm(-2) in 0.500 M H2SO4(aq). To obtain a chemical description of the material as-prepared and also while effecting the HER in acidic media, such electrocatalyst films were investigated using Raman spectroscopy and X-ray absorption spectroscopy both ex situ as well as under in situ and operando conditions in 0...
September 8, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28775316/efficient-functional-neutralization-of-lethal-peptide-toxins-in-vivo-by-oligonucleotides
#13
Tarek Mohamed Abd El-Aziz, Corinne Ravelet, Jordi Molgo, Emmanuelle Fiore, Simon Pale, Muriel Amar, Sawsan Al-Khoury, Jérôme Dejeu, Mahmoud Fadl, Michel Ronjat, Germain Sotoing Taiwe, Denis Servent, Eric Peyrin, Michel De Waard
Medical means to save the life of human patients affected by drug abuse, envenomation or critical poisoning are currently limited. While the compounds at risks are most often well identified, particularly for bioterrorism, chemical intervention to counteract the toxic effects of the ingested/injected compound(s) is restricted to the use of antibodies. Herein, we illustrate that DNA aptamers, targeted to block the pharmacophore of a poisonous compound, represent a fast-acting and reliable method of neutralization in vivo that possesses efficient and long-lasting life-saving properties...
August 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28666482/urolithiasis-secondary-to-primary-obstructive-megaureter-in-an-adult-a-case-report
#14
Somuah Tenkorang, Jean-Paul Omana, Soufiane Mellas, Fadl Mohammed Tazi, Jalal Eddine El Ammari, Abdelhak Khallouk, Mohammed Jamal El Fassi, Moulay Hassan Farih
BACKGROUND: Primary obstructive megaureter is relatively uncommon in adults. This condition usually regresses spontaneously or is treated during infancy. It can remain asymptomatic for decades until adulthood when symptoms may manifest in the event of complications or during a routine radiologic imaging. Primary obstructive megaureter has been reported to favor stone formation in the upper urinary tract. CASE PRESENTATION: We present the case of a 35-year-old Moroccan man who had a 10-year history of intermittent left flank pain and hematuria...
July 1, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28662172/quantitative-proteomics-analysis-of-proteins-involved-in-alkane-uptake-comparing-the-profiling-of-pseudomonas-aeruginosa-sjtd-1-in-response-to-n-octadecane-and-n-hexadecane
#15
COMPARATIVE STUDY
Xuefeng Zhou, Xuejiao Xing, Jingli Hou, Jianhua Liu
While many data are available on genes encoding proteins for degradation of hydrocarbons in bacteria, the impact of alkane on transporter protein expression is unclear. Pseudomonas aeruginosa SJTD-1 is a strain that can consume medium- and long-chain n-alkanes. In order to study the proteins involved in n-octadecane uptake, we use iTRAQ and label free comparative proteomics analysis to identify the proteins of alkane uptake in response to n-octadecane (C18) comparing with n-hexadecane (C16) in P. aeruginosa SJTD-1...
2017: PloS One
https://www.readbyqxmd.com/read/28660527/core-curriculum-illustration-abdominal-wood-impalement-injury-from-motor-vehicle-collision
#16
Shaimaa Abdelhassib Fadl, Annie P Ehlers, Gabriel Wallace, Joel A Gross
This is the 42nd installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at http://www.erad.org/page/CCIP_TOC .
June 28, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28656328/core-curriculum-illustration-blunt-traumatic-diaphragmatic-hernia
#17
Shaimaa Abdelhassib Fadl, Rachael M Edwards
This is the 43rd installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at: http://www.erad.org/page/CCIP_TOC .
June 27, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28631162/core-curriculum-case-illustration-blunt-traumatic-thoracic-aortic-pseudo-aneurysm
#18
Muhammad Mubashir Ramzan, Shaimaa Abdelhassib Fadl, Jeffrey D Robinson
Core Curriculum Illustration: [blunt thoracic aortic pseudo aneurysm]. This is the [40th] installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at: http://www.aseronline.org/curriculum/toc.html...
June 19, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28616788/core-curriculum-case-illustration-cardiac-tamponade-complicating-proximal-aortic-dissection
#19
H Laura Aaltonen, Ken F Linnau, Shaimaa Abdelhassib Fadl
This is the 39th installment of a series that will highlight one case per publication issue from the bank of cases available online as part of the American Society of Emergency Radiology (ASER) educational resources. Our goal is to generate more interest in and use of our online materials. To view more cases online, please visit the ASER Core Curriculum and Recommendations for Study online at http://www.erad.org/page/CCIP_TOC .
June 14, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28595464/the-effects-of-baroreflex-activation-therapy-on-blood-pressure-and-sympathetic-function-in-patients-with-refractory-hypertension-the-rationale-and-design-of-the-nordic-bat-study
#20
Daniel Gordin, Fadl Elmula M Fadl Elmula, Bert Andersson, Anders Gottsäter, Johan Elf, Thomas Kahan, Kent Lodberg Christensen, Pirkka Vikatmaa, Leena Vikatmaa, Thomas Bastholm Olesen, Per-Henrik Groop, Michael Hecht Olsen, Ilkka Tikkanen
OBJECTIVE: To explore the effects of baroreflex activation therapy (BAT) on hypertension in patients with treatment resistant or refractory hypertension. METHODS: This investigator-initiated randomized, double-blind, 1:1 parallel-design clinical trial will include 100 patients with refractory hypertension from 6 tertiary referral hypertension centers in the Nordic countries. A Barostim Neo System will be implanted and after 1 month patients will be randomized to either BAT for 16 months or continuous pharmacotherapy (BAT off) for 8 months followed by BAT for 8 months...
June 8, 2017: Blood Pressure
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