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https://www.readbyqxmd.com/read/27920414/morbidity-and-mortality-and-predictors-of-outcome-following-hepatectomy-at-a-saudi-tertiary-care-center
#1
Faisal Al-Alem, Rafif Essam Mattar, Ola Abdelmonem Fadl, Abdulsalam Alsharabi, Faisal Al-Saif, Mazen Hassanain
BACKGROUND: Hepatic resection is a major surgical procedure. Data on outcomes of hepatectomy in Saudi Arabia are scarce. OBJECTIVE: To measure morbidity and mortality and assess predictors of outcome after hepatectomy. DESIGN: Descriptive study. SETTING: Tertiary care center in Saudi Arabia with well established hepatobiliary surgery unit. PATIENTS AND METHODS: All patients undergoing liver resection in our institute during 2006-2014...
November 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27899949/corrigendum-to-effect-of-narrow-band-ultraviolet-b-phototherapy-and-methotrexate-on-microrna-146a-levels-in-blood-of-psoriatic-patients
#2
Amal Abou El-Fadle, Asmaa M Ele-Refaei, Fatma M El-Esawy
[This corrects the article DOI: 10.1155/2015/145769.].
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27897277/the-structure-of-fadl-mrna-and-its-interactions-with-rybb-srna
#3
Agata Groszewska, Zuzanna Wroblewska, Mikolaj Olejniczak
Small bacterial RNAs (sRNAs) regulate translation by pairing with complementary sequences in their target mRNAs, in a process which is often dependent on the Hfq protein. Here, the secondary structure of a 95-nt long fragment of Salmonella fadL mRNA containing RybB sRNA binding site in the coding region was analyzed. The data indicated local rearrangements in this mRNA structure after the annealing of RybB. The filter retention data had shown that Hfq bound both RybB and the fadL mRNA fragment with tight affinities...
November 25, 2016: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/27880790/integrating-maternal-and-children-s-oral-health-promotion-into-nursing-and-midwifery-practice-a-systematic-review
#4
Reham Abou El Fadl, Mitch Blair, Sondus Hassounah
BACKGROUND: Globally, oral diseases contribute to major disease problems and oral health disparities persistently exist amongst vulnerable population groups. Two contributory factors to these challenges are the shortage of dental practitioners and the characteristic separation between the medical and dental professions. Nurses and midwives, in particular, are in a potentially excellent position to assist in basic oral health services such as dental health education and intraoral screening...
2016: PloS One
https://www.readbyqxmd.com/read/27878786/enhancing-poly-3-hydroxyalkanoate-production-in-escherichia-coli-by-the-removal-of-the-regulatory-gene-arca
#5
Ryan A Scheel, Liyuan Ji, Benjamin R Lundgren, Christopher T Nomura
Recombinant Escherichia coli is a desirable platform for the production of many biological compounds including poly(3-hydroxyalkanoates), a class of naturally occurring biodegradable polyesters with promising biomedical and material applications. Although the controlled production of desirable polymers is possible with the utilization of fatty acid feedstocks, a central challenge to this biosynthetic route is the improvement of the relatively low polymer yield, a necessary factor of decreasing the production costs...
December 2016: AMB Express
https://www.readbyqxmd.com/read/27831977/single-stage-combined-craniofacial-repair-for-frontoethmoidal-meningoencephalocele
#6
Ahmed Gaber Hassanein, Khalid Nasser Fadle
INTRODUCTION: Frontoethmoidal meningoencephalocele (FMEC) is a rare congenital anomaly characterized by herniation of brain tissue and meninges through a defect in the cranium and associated with facial dysmorphism. Treatment modalities include extra cranial, transcranial, or combined craniofacial approaches. The combined approach is considered the best treatment choice. METHODS: Twelve patients with FMEC aging from 6 months to 4 years were treated by single-stage combined craniofacial approach between July 2011 and July 2015...
November 9, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27830341/serum-progranulin-levels-in-hispanic-rheumatoid-arthritis-patients-treated-with-tnf-antagonists-a-prospective-observational-study
#7
Jennifer Johnson, Karen Yeter, Rosy Rajbhandary, Rebekah Neal, Qingyun Tian, Jinlong Jian, Natalie Fadle, Lorenz Thurner, Chuanju Liu, William Stohl
Since progranulin (PGRN) is a natural ligand of TNF receptors, we assessed whether serum PGRN levels predict and/or reflect responsiveness of RA patients to TNF-antagonist therapy. TNF-antagonist-naïve RA patients (N = 35) were started on TNF-antagonist therapy. At baseline and at follow-up visits, DAS28-ESR, DAS28-CRP, and CDAI were calculated, and venous blood was collected for serum PGRN determination. Disease activity and clinical response were based on EULAR criteria. Baseline serum PGRN levels varied considerably and correlated with ESR and CRP...
November 9, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27813832/single-nucleotide-polymorphisms-in-il8-and-tlr4-genes-as-candidates-for-digital-dermatitis-resistance-susceptibility-in-holstein-cattle
#8
El-Sayed El-Shafaey, Ahmed Ateya, Hazem Ramadan, Rasha Saleh, Yousef Elseady, Eman Abo El Fadl, Sabry El-Khodery
Relatedness between single nucleotide polymorphisms in IL8 and TLR4 genes and digital dermatitis resistance/susceptibility was investigated in seventy Holstein dairy cows. Animals were assigned into two groups, affected group (n = 35) and resistant group (n = 35) based on clinical signs and previous history of farm clinical records. Blood samples were collected for DNA extraction to ampliy fragments of 267-bp and 382-bp for IL8 and TLR4 genes, respectively. PCR-DNA sequencing revealed three SNPs in each of IL8 and TLR4 genes...
November 4, 2016: Animal Biotechnology
https://www.readbyqxmd.com/read/27702773/clinical-outcomes-in-3343-children-and-adults-with-rheumatic-heart-disease-from-14-low-and-middle-income-countries-2-year-follow-up-of-the-global-rheumatic-heart-disease-registry-the-remedy-study
#9
Liesl Zühlke, Ganesan Karthikeyan, Mark E Engel, Sumathy Rangarajan, Pam Mackie, Blanche Cupido, Katya Mauff, Shofiqul Islam, Rezeen Daniels, Veronica Francis, Stephen Ogendo, Bernard Gitura, Charles Mondo, Emmy Okello, Peter Lwabi, Mohammed M Al-Kebsi, Christopher Hugo-Hamman, Sahar S Sheta, Abraham Haileamlak, Wandimu Daniel, Dejuma Yadeta Goshu, Senbeta G Abdissa, Araya G Desta, Bekele A Shasho, Dufera M Begna, Ahmed ElSayed, Ahmed S Ibrahim, John Musuku, Fidelia Bode-Thomas, Christopher C Yilgwan, Ganiyu A Amusa, Olukemi Ige, Basil Okeahialam, Christopher Sutton, Rajeev Misra, Azza Abul Fadl, Neil Kennedy, Albertino Damasceno, Mahmoud U Sani, Okechukwu S Ogah, Taiwo Olunuga, Huda ElHassan, Ana Olga Mocumbi, Abiodun M Adeoye, Pindile S Mntla, Dike B Ojji, Joseph Mucumbitsi, Koon Teo, Salim Yusuf, Bongani M Mayosi
BACKGROUND: -There are few contemporary data on the mortality and morbidity associated with rheumatic heart disease (RHD) or information on their predictors. We report the two year follow-up of individuals with RHD from 14 low and middle income countries in Africa and Asia. METHODS: -Between January 2010 and November 2012, we enrolled 3343 patients from 25 centers in 14 countries and followed them for two years to assess mortality, congestive heart failure (CHF), stroke or transient ischemic attack (TIA), recurrent acute rheumatic fever (ARF), and infective endocarditis (IE)...
October 4, 2016: Circulation
https://www.readbyqxmd.com/read/27695652/current-advances-in-the-functional-studies-of-fatty-acids-and-fatty-acid-derived-lipids-in-c-elegans
#10
REVIEW
Lu Ying, Huanhu Zhu
Fatty acids and fatty acid-derived lipids (FAs/FADLs) play essential roles in many living organisms, including contributions to membrane structure and signaling transduction. Aberrant metabolism of FAs/FADLs often causes diseases and health problems. However, the detailed mechanistic studies of specific FAs/FADLs in vivo are limited. C. elegans has been an effective model system for FA/ FADL studies due to its powerful genetics and conserved lipid biosynthetic pathways. The recently developed high-throughput analytic tools also enable sophisticated profiling of lipids molecules in C...
2016: Worm
https://www.readbyqxmd.com/read/27617807/orbitocranial-fibrous-dysplasia-outcome-of-radical-resection-and-immediate-reconstruction-with-titanium-mesh-and-pericranial-flap
#11
Khalid Nasser Fadle, Ahmed Gaber Hassanein, Abdin K Kasim
INTRODUCTION: Fibrous dysplasia (FD) is a non-neoplastic developmental fibro-osseous disease. It represents 2.5% of all bone tumors and 5% to 7% of the benign bone tumors. Orbitocranial region is involved in about 20% of the patients. The main presentations are craniofacial deformity and headache. Loss of vision is the most devastating result of this disease. There is no medical treatment to cure or prevent FD. Radiation therapy is contraindicated. Surgery for the orbitocranial FD is often challenging because of the proximity of neurovascular and ocular structures...
September 9, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27582306/sexually-transmitted-infections-other-than-hiv-aids-among-women-of-low-socio-economic-class-attending-antenatal-clinics-in-khartoum-sudan
#12
Nada A Abdelrahim, Hiba I Ahmed, Imad M Fadl-Elmula, Magdi A Bayoumi, Mamoun M Homeida
Sexually transmitted infections (STIs) are major health threats affecting people globally; however, the burden of STIs is greatest in low-income countries. Since they are physiologically more vulnerable, women are mostly affected. The risk is increased dramatically during pregnancy leading to serious health complications that may affect the newborn. Underprivileged pregnant women attending antenatal clinics for routine checkups in displaced camps, a women's prison and several peripheral health centres were clinically and laboratory screened for trichomoniasis, chlamydial infections, gonorrhea and syphilis...
August 31, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27557918/effect-of-tooth-mousse-on-streptococcus-mutans-in-the-plaque-of-high-caries-risk-preschool-children-a-triple-blind-randomized-clinical-trial
#13
Amira N Fadl, Magda M ElTekeya, Karin L Dowidar, Nadia Mokhles, Maha M El Tantawi
PURPOSE: Control of Streptococcus mutans can prevent caries in high-risk preschool children. The purpose of this study was to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) on Streptococcus mutans in the plaque of high-risk preschool children. METHODS: A triple blind, randomized, controlled clinical trial included 40 healthy three- to five-year-olds with at least one white spot lesion. They were randomized into test (daily applications of GC Tooth Mousse:CPP-ACP) and control groups (placebo mousse)...
2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/27547412/trends-in-diabetes-in-pregnancy-in-sweden-1998-2012
#14
Helena E Fadl, David Simmons
OBJECTIVE: Diabetes in pregnancy has been shown to increase in parallel with the increasing prevalence of obesity. In this national population-based study, we analyzed the trends for gestational diabetes mellitus (GDM), type 1 diabetes in pregnancy, and type 2 diabetes in pregnancy in Sweden between 1998 and 2012. RESEARCH DESIGN AND METHODS: A population-based cohort study using the Swedish national medical birth registry data. The time periods were categorized into 3-year intervals and adjusted for maternal body mass index (BMI), ethnicity, and age in a logistic regression...
2016: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/27508849/-op-7d-07-influence-of-renal-sympathetic-denervation-on-blood-pressure-variability-experience-at-11-european-expert-centers
#15
A Persu, D Gordin, L Jacobs, L Thijs, M L Bots, A Miroslawska, J Spaak, J Rosa, M De Jong, E Berra, F E Fadl Elmula, G Wuerzner, A Taylor, A Olszanecka, D Czarnecka, P B Mark, M Burnier, J Renkin, S E Kjeldsen, J Widimsky, A Elvan, T Kahan, T Steigen, P J Blankestijn, I Tikkanen, J A Staessen
OBJECTIVE: Sympathetic tone is one of the main determinants of blood pressure (BP) variability. The aim of our study was to assess the changes in BP variability after renal sympathetic denervation (RDN) in resistant hypertensive patients, and, conversely, to look for the predictive value of baseline BP variability on mean BP changes after RDN. DESIGN AND METHOD: Twenty-four hour BP measurements were analyzed in 167 resistant hypertensive patients recruited at 11 expert centers within the European Network Coordinating research on Renal Denervation (ENCOReD) (mean age 56...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27348058/utilization-of-the-track-embolization-technique-to-improve-the-safety-of-percutaneous-lung-biopsy-and-or-fiducial-marker-placement
#16
Amanjit S Baadh, Jason C Hoffmann, Ahmed Fadl, Dipan Danda, Vijay R Bhat, Nicholas Georgiou, Man Hon
PURPOSE: The purpose of the study was to describe and present outcomes of the track embolization technique with absorbable hemostat gelatin powder during percutaneous computed tomography (CT)-guided lung biopsy and/or fiducial marker placement versus the standard of care (no track embolization) in an attempt to decrease rates of pneumothorax (PTX), chest tube placement, hemorrhage and/or complications, and average cost per patient. MATERIALS AND METHODS: An institutional review board-approved, case-control, retrospective study was performed in which 125 consecutive patients who underwent track embolization were compared with 124 consecutive controls at one institution...
September 2016: Clinical Imaging
https://www.readbyqxmd.com/read/27335608/comparative-hepatotoxicity-of-aflatoxin-b1-among-workers-exposed-to-different-organic-dust-with-emphasis-on-polymorphism-role-of-glutathione-s-transferase-gene
#17
Amal Saad-Hussein, Eman M Shahy, Weam Shaheen, Mona M Taha, Heba Mahdy-Abdallah, Khadiga S Ibrahim, Salwa F Hafez, Nevein N Fadl, Karima A El-Shamy
AIM: The study aimed to investigate effects of organic dust exposure from different sources on aflatoxin B1-albumin adducts (AFB1/Alb), and role of glutathione S-transferase (GST) gene polymorphism in hepatotoxicity of (AFB1) among exposed workers. MATERIAL AND METHODS: Liver enzymes, AFB1/Alb, and GST polymorphism were estimated in 132 wheat flour dust and 87 woods sawmill workers, and 156 controls. RESULTS: Results revealed that AFB1/Alb and liver enzymes were significantly elevated in exposed workers compared to controls, and were significantly higher in sawmill workers compared to flour workers...
June 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27272370/-medication-adherence-and-monitoring-of-antihypertensive-treatment
#18
Per Anders Eskås, Sondre Heimark, Julian Eek Mariampillai, Anne Cecilie K Larstorp, Fadl Elmula Mohamed Fadl Elmula, Aud Høieggen
Lack of adherence to medication may be the explanation for unsatisfactory drug efficacy and is often misinterpreted as resistance to treatment. When encountering patients with persistent high blood pressure despite antihypertensive treatment, it is therefore important to discover whether they are actually taking their medication. This article aims to provide an updated overview of methods of revealing and monitoring medication adherence. The article is based on non-systematic literature searches in PubMed and on the senior authors' own clinical experience...
June 2016: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/27172974/overweight-and-obesity-a-remaining-problem-in-women-treated-for-severe-gestational-diabetes
#19
K Hildén, U Hanson, M Persson, H Fadl
AIM: To analyse the impact of overweight and obesity on the risk of adverse maternal outcomes and fetal macrosomia in pregnancies of women treated for severe gestational diabetes. METHODS: This was a population-based cohort study including all singleton pregnancies in Sweden without pre-existing diabetes in the period 1998-2012. Only mothers with an early- pregnancy BMI of ≥ 18.5 kg/m² were included. Logistic regression analysis was used to determine odds ratios with 95% CIs for maternal outcomes and fetal growth...
August 2016: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/27124769/tertiary-work-up-of-apparent-treatment-resistant-hypertension
#20
Sondre Heimark, Per Anders Eskås, Julian Eek Mariampillai, Anne Cecilie K Larstorp, Aud Høieggen, Fadl Elmula M Fadl Elmula
OBJECTIVE: Treatment-resistant hypertension (TRH) has regained attention with development of new methods for treatment. However, the prevalence of TRH varies considerably from primary to secondary and tertiary care. We aimed to assess the prevalence of true TRH in a population of patients with apparent TRH in a university hospital setting of tertiary work-up and also investigate reasons for poor BP control and evaluate how work-up can be performed in general practice and secondary care...
October 2016: Blood Pressure
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