Jing Ma, Xiaoling Liu, Lei Qiao, Linlin Meng, Xingli Xu, Fei Xue, Cheng Cheng, Ziqi Han, Yue Lu, Wencheng Zhang, Peili Bu, Meng Zhang, Guipeng An, Huixia Lu, Mei Ni, Cheng Zhang, Yun Zhang
BACKGROUND: Progression of nontarget lesions (NTLs) after percutaneous coronary intervention (PCI) has been reported. However, it remains unknown whether progression of NTLs was causally related to stenting. This study was undertaken to test the hypothesis that stent implantation triggers acute phase response and systemic inflammation which may be associated with progression of NTLs. METHODS: Thirty New Zealand rabbits receiving endothelial denudation and atherogenic diet were randomly divided into stenting, sham, and control groups...
November 2021: Circulation. Cardiovascular Interventions