Stephen Zewinger, Christiane Drechsler, Marcus E Kleber, Alexander Dressel, Julia Riffel, Sarah Triem, Marlene Lehmann, Chantal Kopecky, Marcus D Säemann, Philipp M Lepper, Günther Silbernagel, Hubert Scharnagl, Andreas Ritsch, Barbara Thorand, Tonia de las Heras Gala, Stefan Wagenpfeil, Wolfgang Koenig, Annette Peters, Ulrich Laufs, Christoph Wanner, Danilo Fliser, Thimoteus Speer, Winfried März
AIMS: High-density lipoproteins (HDLs) are considered as anti-atherogenic. Recent experimental findings suggest that their biological properties can be modified in certain clinical conditions by accumulation of serum amyloid A (SAA). The effect of SAA on the association between HDL-cholesterol (HDL-C) and cardiovascular outcome remains unknown. METHODS AND RESULTS: We examined the association of SAA and HDL-C with mortality in the Ludwigshafen Risk and Cardiovascular Health (LURIC) study, which included 3310 patients undergoing coronary angiography...
November 14, 2015: European Heart Journal