keyword
MENU ▼
Read by QxMD icon Read
search

Wells criteria

keyword
https://www.readbyqxmd.com/read/29045979/-changes-of-serum-krebs-von-den-lungen-6-levels-in-interstitial-lung-disease-associated-with-dermatomyositis-and-secondary-sj%C3%A3-gren-s-syndrome-a-case-report
#1
J F Yu, Y B Jin, J He, Y An, Z G Li
Interstitial lung diseases (ILDs) are a diverse group of pulmonary disorders characterized by various patterns of inflammation and fibrosis in the interstitium of the lung. The underlying pathogenesis of ILDs is complex and associated with multiple rheumatologic conditions, such as systemic sclerosis, rheumatoid arthritis, pollymyositis and dermatomyositis, Sjögren's syndrome, and systemic lupus erythematosus. As the disease progresses, excessive pulmonary fibrosis impairs alveolar gas exchange and damages pulmonary function...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045807/evidence-reversal-when-new-evidence-contradicts-current-claims-a-systematic-overview-review
#2
REVIEW
Desirée Sutton, Riaz Qureshi, Janet Martin
OBJECTIVE: To explore the terminology and definitions surrounding the phenomenon of Evidence Reversal - which occurs when an existing claim is tested and the original evidence is contradicted by new and stronger evidence. STUDY DESIGN AND SETTING: For this overview systematic review, multiple medical and grey literature databases were systematically searched from inception to 2016 as well as hand searches of relevant journals, websites, blogs, article bibliographies, citing articles, and related articles...
October 15, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29045753/association-between-the-rs1229984-polymorphism-in-the-alcohol-dehydrogenase-b-adh1b-gene-and-risk-for-restless-legs-syndrome
#3
Félix Javier Jiménez-Jiménez, Javier Gómez-Tabales, Hortensia Alonso-Navarro, Martín Zurdo, Laura Turpín-Fenoll, Jorge Millán-Pascual, Teresa Adeva-Bartolomé, Esther Cubo, Francisco Navacerrada, Ana Rojo-Sebastián, Lluisa Rubio, Mónica Díez-Fairén, Pau Pastor, Marisol Calleja, José Francisco Plaza-Nieto, Belén Pilo-de-la-Fuente, Margarita Arroyo-Solera, Esteban García-Albea, José A G Agúndez, Elena García-Martín
Background/Objective: Several studies have raised the possibility of an association between alcohol consumption and the risk of developing restless legs syndrome (RLS). Moreover, an important percentage of patients under alcohol detoxification therapy develop RLS symptoms fulfil the criteria for idiopathic RLS during alcohol withdrawal. We have aimed to establish the possible association between 2 common single nucleotide polymorphisms (SNPs) in the alcohol-dehydrogenase 1B (ADH1B) gene, and the risk for RLS...
October 16, 2017: Sleep
https://www.readbyqxmd.com/read/29045540/phase-ii-trial-of-pembrolizumab-in-patients-with-platinum-refractory-germ-cell-tumors-a-hoosier-cancer-research-network-study-gu14-206
#4
N Adra, L H Einhorn, S K Althouse, N R Ammakkanavar, D Musapatika, C Albany, D Vaughn, N H Hanna
Background: Despite remarkable results with salvage standard-dose or high-dose chemotherapy about 15% of patients with relapsed germ-cell tumors (GCT) are incurable. Immune checkpoint inhibitors have produced significant remission in multiple tumor types. We report the first study of immunotherapy in patients with GCT. Patients and Methods: Single arm phase 2 trial investigating pembrolizumab 200mg IV Q3weeks until disease progression in patients with relapsed GCT and no curable options...
October 17, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29045409/psychometric-validation-of-the-italian-rehabilitation-complexity-scale-extended-version-13
#5
Francesca Roda, Maurizio Agosti, Andrea Merlo, Maurizio Maini, Francesco Lombardi, Claudio Tedeschi, Maria Grazia Benedetti, Nino Basaglia, Mara Contini, Domenico Nicolotti, Rodolfo Brianti
In Italy, at present, a well-known problem is inhomogeneous provision of rehabilitative services, as stressed by MoH, requiring appropriate criteria and parameters to plan rehabilitation actions. According to the Italian National Rehabilitation Plan, Comorbidity, Disability and Clinical Complexity should be assessed to define the patient's real needs. However, to date, clinical complexity is still difficult to measure with shared and validated tools. The study aims to psychometrically validate the Italian Rehabilitation Complexity Scale-Extended v13 (RCS-E v13), in order to meet the guidelines requirements...
2017: PloS One
https://www.readbyqxmd.com/read/29044787/intracardiac-ablation-for-atrioventricular-nodal-reentry-tachycardia-using-a-6%C3%A2-mm-distal-electrode-cryoablation-catheter-prospective-multicenter-north-american-study-icy-avnrt-study
#6
Peter Wells, Marc Dubuc, George J Klein, Dan Dan, Jean-Francois Roux, Evan Lockwood, Marcio Sturmer, David Dunbar, Paul Novak, Arun Rao, Brett J Peterson, Fred Kueffer, Kenneth A Ellenbogen
INTRODUCTION: Radiofrequency (RF) ablation is effective for slow pathway ablation, but carries a risk of inadvertent AV block requiring permanent pacing. By comparison, cryoablation with a 4 mm distal electrode catheter has not been reported to cause permanent AV block but has been shown to be less effective than RF ablation. We sought to define the safety and efficacy of a 6 mm distal electrode cryoablation catheter for slow pathway ablation in patients with atrioventricular nodal reentry tachycardia (AVNRT)...
October 17, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29044682/systematic-review-and-meta-analysis-of-liver-transplantation-using-grafts-from-deceased-donors-aged-over-70-years
#7
REVIEW
B V Dasari, H Mergental, J R Isaac, P Muiesan, D F Mirza, M T P R Perera
INTRODUCTION: Due to the current organ shortage, nearly 20% of patients die waiting for a liver transplant (LT). The average donor age is on the rise, and grafts from elderly donors are offered as extended criteria grafts. METHODS: This is a meta-analysis comparing the outcome differences of adult patients undergoing LT using grafts from <70-year-old donors versus >70-year-old donors. The primary end-points were graft and patient survival. Secondary outcomes were biliary and vascular complications as well as graft function...
October 17, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29044289/preoperative-diagnostics-in-differentiated-thyroid-carcinoma
#8
Philipp Seifert, Martin Freesmeyer
AIM: The preoperative diagnosis of differentiated thyroid carcinomas (DTC) is particularly challenging in view of the high prevalence of thyroid nodules in the general population. Incidental diagnosis of DTC, on the other hand, can lead to reoperations and increased risk of morbidity. This study aimed to assess the prediction value of preoperative DTC dignity assessment and it's impact on surgical approaches. METHODS: We retrospectively reviewed 107 cases of DTC and subdivided them in three groups based on the preoperative dignity assessment: suspected malignancy (SM), unclear dignity (UD), and incidental findings (IF)...
October 18, 2017: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/29043599/shenyi-capsule-plus-chemotherapy-versus-chemotherapy-for-non-small-cell-lung-cancer-a-systematic-review-of-overlapping-meta-analyses
#9
Xiu-Wei Guo, Nai-Dong Hu, Gui-Zhi Sun, Meng Li, Pei-Tong Zhang
OBJECTIVE: To assist decision-makers interpret and choose among conflicting meta-analyses, as well as to offer treatment recommendations based on current best evidence by performing a systematic review of overlapping meta-analyses regarding Shenyi Capsule (, SC) plus chemotherapy versus chemotherapy of non-small cell lung cancer (NSCLC). METHODS: A literature search was conducted to select systematic reviews comparing SC plus chemotherapy with chemotherapy for NSCLC...
October 18, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29043571/an-uncertainty-based-framework-to-quantifying-climate-change-impacts-on-coastal-flood-vulnerability-case-study-of-new-york-city
#10
Zahra Zahmatkesh, Mohammad Karamouz
The continued development efforts around the world, growing population, and the increased probability of occurrence of extreme hydrologic events have adversely affected natural and built environments. Flood damages and loss of lives from the devastating storms, such as Irene and Sandy on the East Coast of the USA, are examples of the vulnerability to flooding that even developed countries have to face. The odds of coastal flooding disasters have been increased due to accelerated sea level rise, climate change impacts, and communities' interest to live near the coastlines...
October 17, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29042785/mlc601-in-vascular-dementia-an-efficacy-and-safety-pilot-study
#11
Hossein Pakdaman, Ali Amini Harandi, Koroush Gharagozli, Mehdi Abbasi, Majid Ghaffarpour, Farzad Ashrafi, Hosein Delavar Kasmaei, Asghar Amini Harandi
BACKGROUND AND AIM: Vascular dementia (VaD) is the second most common cause of dementia and currently there is scarcity of therapies for VaD. We aimed to investigate the efficacy and safety of MLC601 in the treatment of VaD. METHODS: In this multicenter, pilot, randomized, double-blind trial, 82 patients with VaD according to DSM-5 criteria received MLC601 or placebo capsules three times a day for 2 years. The primary efficacy end-point was evaluated by comparing Mini-Mental State Examination (MMSE) and Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) score between the two groups over 2 years of study...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29042344/mommio-s-recipe-box-assessment-of-the-cooking-habits-of-mothers-of-preschoolers-and-their-perceptions-of-recipes-for-a-video-game
#12
Maciel Ugalde, Leah Brand, Alicia Beltran, Hafza Dadabhoy, Tzu-An Chen, Teresia M O'Connor, Sheryl O Hughes, Tom Baranowski, Richard Buday, Theresa A Nicklas, Janice Baranowski
BACKGROUND: Vegetables are an important part of a healthy diet because they help prevent several chronic diseases. Mothers of preschoolers reported difficulty getting their young children to eat vegetables, and many did not know how to cook child-pleasing recipes. OBJECTIVE: The cooking habits of mothers of preschoolers, their perceptions of recipes designed for their children, and the involvement of their children in food preparation were assessed to inform a food parenting video game called Mommio...
October 17, 2017: JMIR Serious Games
https://www.readbyqxmd.com/read/29042148/histopathology-of-3%C3%A2-tesla-mri-negative-temporal-lobe-epilepsies
#13
Evangelos Kogias, Dirk-Matthias Altenmüller, Jan-Helge Klingler, Barbara Schmeiser, Horst Urbach, Soroush Doostkam
INTRODUCTION: Histopathology of MRI-negative temporal lobe epilepsies (TLE) shows heterogeneous findings. The use of either 1.5 or 3 Tesla MRI for the selection of MRI-negative cases and use of older classification systems instead of the current ILAE classification system may account for this heterogeneity. We focus on histopathology of 3 Tesla MRI-negative TLE according to ILAE criteria and investigate potential correlation to seizure outcome 1 year postoperatively. MATERIALS AND METHODS: Twenty specimens (9 neocortical, 11 hippocampal) from eleven 3 Tesla MRI-negative patients with TLE were examined in two steps...
October 14, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29040893/quality-of-online-information-on-breast-cancer-treatment-options
#14
Nadia Arif, Pietro Ghezzi
Offering breast cancer patients treatment choice has become a priority as the involvement of patients in the decision-making process is associated with improved physical and psychological outcomes. As the Internet is increasingly being used by patients as a source of medical information, it is important to evaluate the quality of information relating to breast cancer on the Internet. We analysed 200 websites returned by google.co.uk searching "breast cancer treatment options" in terms of their typology and treatment options described...
October 14, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29040759/cervical-alignment-changes-in-patients-developing-proximal-junctional-kyphosis-following-surgical-correction-of-adult-spinal-deformity
#15
Peter G Passias, Samantha R Horn, Cyrus M Jalai, Subaraman Ramchandran, Gregory W Poorman, Han Jo Kim, Justin S Smith, Daniel Sciubba, Alexandra Soroceanu, Christopher P Ames, D Kojo Hamilton, Robert Eastlack, Douglas Burton, Munish Gupta, Shay Bess, Virginie Lafage, Frank Schwab
BACKGROUND: Proximal junctional kyphosis (PJK) following adult spinal deformity (ASD) surgery is a well-documented complication, but associations between radiographic PJK and cervical malalignment onset remain unexplored. OBJECTIVE: To study cervical malalignment in ASD surgical patients that develop PJK. METHODS: Retrospective review of prospective multicenter database. Inclusion: primary ASD patients (≥5 levels fused, upper instrumented vertebra [UIV] at T2 or above, and 1-yr minimum follow-up) without baseline cervical deformity (CD), defined as ≥2 of the following criteria: T1 slope minus cervical lordosis < 20°, cervical sagittal vertical axis < 4 cm, C2-C7 cervical lordosis < 10°...
October 12, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29040589/corifollitropin-alfa-followed-by-highly-purified-hmg-versus-recombinant-fsh-in-young-poor-ovarian-responders-a-multicentre-randomized-controlled-clinical-trial
#16
Panagiotis Drakopoulos, Thi Ngoc Lan Vuong, Ngoc Anh Vu Ho, Alberto Vaiarelli, Manh Tuong Ho, Christophe Blockeel, Michel Camus, Anh Tuan Lam, Arne van de Vijver, Peter Humaidan, Herman Tournaye, Nikolaos P Polyzos
STUDY QUESTION: Does administration of corifollitropin alfa followed by highly purified (hp) HMG result in higher ongoing pregnancy rates compared with daily recombinant FSH (rFSH) in young poor responders? SUMMARY ANSWER: Corifollitropin alfa followed by hp-HMG does not increase ongoing pregnancy rates compared with rFSH in young poor responders, although more supernumerary cryopreserved embryos were obtained with corifollitropin alfa and hp-HMG. WHAT IS KNOWN ALREADY: Poor ovarian response remains one of the main therapeutic challenges in women undergoing ovarian stimulation, given that very low live birth rates of 6% have been reported in this particular group of infertile patients...
September 23, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29040582/cdc73-related-disorders-clinical-manifestations-and-case-detection-in-primary-hyperparathyroidism
#17
Karin van der Tuin, Carli M J Tops, Muriel A Adank, Jan-Maarten Cobben, Neveen A T Hamdy, Marjolijn C Jongmans, Fred H Menko, Bernadette P M van Nesselrooij, Romana T Netea-Maier, Jan C Oosterwijk, Gerlof D Valk, Bruce H R Wolffenbuttel, Frederik J Hes, Hans Morreau
Context: Heterozygous pathogenic germline variants in CDC73 predispose to the development of primary hyperparathyroidism (pHPT), and less frequently, ossifying fibroma of the jaw and renal and uterine tumors. Clinical information on CDC73-related disorders has so far been limited to small case series. Objective: To assess the clinical manifestations and penetrance in CDC73-related disorders and to improve case detection in pHPT. Design: Nationwide retrospective Dutch cohort study...
October 12, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29039729/antimicrobial-activity-of-ceftolozane-tazobactam-tested-against-enterobacteriaceae-and-pseudomonas-aeruginosa-with-various-resistance-patterns-isolated-in-u-s-hospitals-2013-2016-as-part-of-the-surveillance-program-program-to-assess-ceftolozane-tazobactam-susceptibility
#18
Dee Shortridge, Michael A Pfaller, Mariana Castanheira, Robert K Flamm
This study evaluated the in vitro activity of ceftolozane-tazobactam and comparator agents tested against Enterobacteriaceae and Pseudomonas aeruginosa isolates from hospitalized patients in the United States. Ceftolozane-tazobactam is an antipseudomonal cephalosporin combined with a well-established β-lactamase inhibitor. A total of 18,960 organisms (15,223 Enterobacteriaceae and 3,737 P. aeruginosa) were consecutively collected from 32 medical centers located in all nine U.S. census divisions from 2013 to 2016...
October 17, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29039685/health-technology-assessment-process-of-a-cardiovascular-medical-device-in-four-different-settings
#19
Antonio Olry de Labry Lima, Jaime Espín Balbino, Alexandre Lemgruber, Araceli Caro Martínez, Leticia García-Mochón, Eva Martín Ruiz, Fernanda Lessa
AIM: Health technology assessment (HTA) is a tool to help the decision-making process. The aim is to describe methods and processes used in the reimbursement decision making for drug-eluting stents (DES) in four different settings. METHODS: DES as a technology under study was selected according to different criteria, all of them agreed by a working group. A survey of key informants was designed. RESULTS: DES was evaluated following well-structured HTA processes...
October 17, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29039320/pharmacokinetic-and-bioequivalence-studies-of-fast-dispersible-ketoprofen-tablets-in-healthy-volunteers
#20
Farya Zafar, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Huma Ali, Rabia Bushra
In the present study the pharmacokinetic and bioequivalence parameter of Ketoprofen 100 mg fast dispersible tablets (test) were measured with marketed (reference) product. This study was accomplished following FDA guidance. A single dose, open labeled, cross over (two way), randomized study design was used to conduct investigation on 12 Pakistani healthy volunteers. At various time points blood samples (10mL) were drawn i.e. at 0.25, 0.5, 1, 1.5, 2, 3, 4, 8, 12 and 13hr. Plasma was then separated and ketoprofen concentrations were estimated by validated HPLC technique using LC 20A pump (Shimadzu Corp, Japan) and Spectrophotometric SPD-20Adetector (Shimadzu Corp, Japan)...
July 2017: Pakistan Journal of Pharmaceutical Sciences
keyword
keyword
82030
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"