keyword
https://read.qxmd.com/read/38485484/heart-failure-clinic-inclusion-and-exclusion-criteria-cross-sectional-study-of-clinic-s-and-referring-provider-s-perspectives
#1
JOURNAL ARTICLE
Taslima Mamataz, Sean A Virani, Michael McDonald, Heather Edgell, Sherry L Grace
OBJECTIVES: There are substantial variations in entry criteria for heart failure (HF) clinics, leading to variations in whom providers refer for these life-saving services. This study investigated actual versus ideal HF clinic inclusion or exclusion criteria and how that related to referring providers' perspectives of ideal criteria. DESIGN, SETTING AND PARTICIPANTS: Two cross-sectional surveys were administered via research electronic data capture to clinic providers and referrers (eg, cardiologists, family physicians and nurse practitioners) across Canada...
March 14, 2024: BMJ Open
https://read.qxmd.com/read/38461741/optimal-blood-pressure-for-stroke-prevention-in-healthy-adults-below-65-years-a-nationwide-10-year-observational-study
#2
JOURNAL ARTICLE
So Im Ryu, Sang Hyo Lee, Hyoung Soo Byoun, Young-Deok Kim, Seung Pil Ban, Jae Seung Bang, O-Ki Kwon, Chang Wan Oh, Si Un Lee
BACKGROUND: There have been few reports on the preventative value of intensive blood pressure (BP) management for stroke since the American College of Cardiology/American Heart Association (ACC/AHA) announced the new criteria for hypertension (HTN) in 2017. This study aimed to identify optimal BP for prevention of stroke in healthy adults under 65 years. METHODS: We conducted a 10-year observational study on the risk of stroke, subclassified as hemorrhagic stroke (HS) or ischemic stroke (IS), according to BP categories (low-normal BP, high-normal BP, elevated BP, stage 1 HTN, and stage 2 HTN) using the National Health Insurance Service Database...
March 9, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://read.qxmd.com/read/38456903/-drug-therapy-for-arterial-hypertension-and-atrial-fibrillation-in-frail-patients-are-there-any-new-insights-and-recommendations
#3
REVIEW
Ursula Müller-Werdan
The frail and elderly are considered to be at particular risk of suffering an adverse drug reaction. Empirical studies confirm the increased rate of adverse drug reactions. Whether frailty per se impairs drug metabolism or the underlying organ ageing processes and multimorbidity cannot be answered with certainty based on current data. Cardiovascular diseases exhibit a considerable interdependence with frailty. For example, there is a disproportionate syndromal interdependence between heart failure and frailty, and the typical ageing processes of the sinus node can be interpreted as heartbeat frailty...
March 8, 2024: Inn Med (Heidelb)
https://read.qxmd.com/read/38447271/cardiometabolic-health-markers-among-aboriginal-adolescents-from-the-next-generation-youth-wellbeing-cohort-study
#4
JOURNAL ARTICLE
Christopher D McKay, Lina Gubhaju, Alison J Gibberd, Bridgette J McNamara, Emily Banks, Peter Azzopardi, Robyn Williams, Sandra Eades
OBJECTIVE: The objective of this study was to investigate cardiometabolic health markers among Aboriginal adolescents aged 10-24 years and relationships with age, gender, and body composition. METHODS: Baseline data (2018-2020) from the Next Generation Youth Wellbeing Cohort Study (Western Australia, New South Wales, and Central Australia) on clinically assessed body mass index, waist/height ratio, blood pressure, glycated haemoglobin (HbA1c), total and high-density lipoprotein cholesterol, total/high-density lipoprotein cholesterol ratio, and triglycerides were analysed...
March 5, 2024: Australian and New Zealand Journal of Public Health
https://read.qxmd.com/read/38410954/mpap-co-slope-and-oxygen-uptake-add-prognostic-value-in-aortic-stenosis
#5
JOURNAL ARTICLE
Sarah Hoedemakers, Nicola Riccardo Pugliese, Jan Stassen, Arnaud Vanoppen, Jade Claessens, Tin Gojevic, Youri Bekhuis, Maarten Falter, Sara Moura Ferreira, Sebastiaan Dhont, Nicolò De Biase, Lavinia Del Punta, Valerio Di Fiore, Marco De Carlo, Cristina Giannini, Andrea Colli, Raluca Elena Dulgheru, Jolien Geers, Alaaddin Yilmaz, Guido Claessen, Philippe Bertrand, Steven Droogmans, Patrizio Lancellotti, Bernard Cosyns, Frederik H Verbrugge, Lieven Herbots, Stefano Masi, Jan Verwerft
BACKGROUND: Recent guidelines redefined exercise pulmonary hypertension as a mean pulmonary artery pressure/cardiac output (mPAP/CO) slope >3 mm Hg·L-1 ·min-1 . A peak systolic pulmonary artery pressure >60 mm Hg during exercise has been associated with an increased risk of cardiovascular death, heart failure rehospitalization, and aortic valve replacement in aortic valve stenosis. The prognostic value of the mPAP/CO slope in aortic valve stenosis remains unknown...
February 27, 2024: Circulation
https://read.qxmd.com/read/38399561/refractory-iga-nephropathy-a-challenge-for-future-nephrologists
#6
JOURNAL ARTICLE
Vincenzo Di Leo, Francesca Annese, Federica Papadia, Maria Serena Russo, Marica Giliberti, Fabio Sallustio, Loreto Gesualdo
IgA nephropathy (IgAN) represents the most prevalent form of primary glomerulonephritis, and, on a global scale, it ranks among the leading culprits behind end-stage kidney disease (ESKD). Presently, the primary strategy for managing IgAN revolves around optimizing blood pressure and mitigating proteinuria. This is achieved through the utilization of renin-angiotensin system (RAS) inhibitors, namely, angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs). As outlined by the KDIGO guidelines, individuals who continue to show a persistent high risk of progressive ESKD, even with comprehensive supportive care, are candidates for glucocorticoid therapy...
February 5, 2024: Medicina
https://read.qxmd.com/read/38391284/updates-in-the-management-of-cancer-therapy-related-hypertension
#7
JOURNAL ARTICLE
Prerna Gupta, Mario Enrico Canonico, Christian Faaborg-Andersen, Nicole Prabhu, Lavanya Kondapalli, Raymundo A Quintana
PURPOSE OF REVIEW: To provide a comprehensive review of hypertension among patients with cancer. Several cancer therapies cause hypertension which has resulted in a growing and vulnerable population of patients with difficult to control hypertension which has significant downstream effects. RECENT FINDINGS: Hypertension affects up to 50% of cancer patients and higher comorbidity when compared to the general population. Many anticancer therapies can cause hypertension through their treatment effect...
February 26, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38378735/primary-results-of-the-brazilian-registry-of-atherothrombotic-disease-neat
#8
JOURNAL ARTICLE
Pedro G M de Barros E Silva, Charlene Troiani do Nascimento, Rodrigo Pinto Pedrosa, Marcelo Arruda Nakazone, Michel Ulloffo do Nascimento, Leiliandry de Araújo Melo, Osvaldo Lourenço Silva Júnior, Sérgio Luiz Zimmermann, Rodrigo Morel Vieira de Melo, Ricardo Reinaldo Bergo, Dalton Bertolim Precoma, Lucas Tramujas, Eduardo Gomes Lima, João Miguel Malta Dantas, Antônio Cláudio do Amaral Baruzzi, Ronald Luiz Gomes Flumignan, Maria Sanali Moura de Oliveira Paiva, Luís Henrique Wolff Gowdak, Priscila Nasser de Carvalho, José Albuquerque de Figueiredo Neto, Odilson Marcos Silvestre, Alexandre Fioranelli, Ricardo D 'Oliveira Vieira, Ana Clara Peneluppi Horak, Debora Harumi Kodama Miyada, Flávia Cristina Soares Kojima, Júlia Souza de Oliveira, Leila de Oliveira Silva, Ricardo Pavanello, Eduardo Ramacciotti, Renato D Lopes
There is limited contemporary prospective real-world evidence of patients with chronic arterial disease in Latin America. The Network to control atherothrombosis (NEAT) registry is a national prospective observational study of patients with known coronary (CAD) and/or peripheral arterial disease (PAD) in Brazil. A total of 2,005 patients were enrolled among 25 sites from September 2020 to March 2022. Patient characteristics, medications and laboratorial data were collected. Primary objective was to assess the proportion of patients who, at the initial visit, were in accordance with good medical practices (domains) for reducing cardiovascular risk in atherothrombotic disease...
February 20, 2024: Scientific Reports
https://read.qxmd.com/read/38365947/a-european-renal-association-era-synopsis-for-nephrology-practice-of-the-2023-european-society-of-hypertension-esh-guidelines-for-the-management-of-arterial-hypertension
#9
JOURNAL ARTICLE
Pantelis Sarafidis, Roland Schmieder, Michel Burnier, Alexandre Persu, Andrzej Januszewicz, Jean-Michel Halimi, Mustafa Arici, Alberto Ortiz, Christoph Wanner, Giuseppe Mancia, Reinhold Kreutz
In June 2023, the European Society of Hypertension (ESH) presented and published the new 2023 ESH Guidelines for the Management of Arterial Hypertension, a document that was endorsed by the European Renal Association (ERA). Following the evolution of evidence in recent years, several novel recommendations relevant to the management of hypertension in patients with chronic kidney disease (CKD) appeared in these Guidelines. These include recommendations for target office BP < 130/80 mmHg in most and against target office BP < 120/70 mmHg in all patients with CKD; recommendations for use of spironolactone or chlortalidone for patients with resistant hypertension with eGFR higher or lower than 30 ml/min/1...
February 14, 2024: Nephrology, Dialysis, Transplantation
https://read.qxmd.com/read/38312786/updates-on-new-therapies-for-patients-with-ckd
#10
REVIEW
Tushar Tarun, Sai Nikhila Ghanta, Vincz Ong, Rajshekhar Kore, Lakshmi Menon, Csaba Kovesdy, Jawahar L Mehta, Nishank Jain
Individuals diagnosed with chronic kidney disease (CKD) continue to increase globally. This group of patients experience a disproportionately higher risk of cardiovascular (CV) events compared to the general population. Despite multiple guidelines-based medical management, patients with CKD continue to experience residual cardiorenal risk. Several potential mechanisms explain this excessive CV risk observed in individuals with CKD. Several new drugs have become available that could potentially transform CKD care, given their efficacy in this patient population...
January 2024: KI Reports
https://read.qxmd.com/read/38304688/the-management-of-preeclampsia-a-comprehensive-review-of-current-practices-and-future-directions
#11
REVIEW
Dhruvikumari D Sharma, Nidhi R Chandresh, Ayesha Javed, Peter Girgis, Madiha Zeeshan, Syeda Simrah Fatima, Taneen T Arab, Sreeja Gopidasan, Vineesha Chowdary Daddala, Kalgi V Vaghasiya, Ameena Soofia, Maneeth Mylavarapu
Preeclampsia (PE) is a disease in pregnancy that is characterized by new-onset hypertension end-organ dysfunction, often occurring after 20 weeks of gestation. Risk factors include a prior history of PE, diabetes, kidney disease, obesity, and high maternal age at pregnancy. Current treatment and management guidelines focus on the management of high blood pressure and any potential complications. The only known curative treatment is termination of pregnancy (either induction of delivery or cesarean section)...
January 2024: Curēus
https://read.qxmd.com/read/38260693/barriers-to-optimal-clinician-guideline-adherence-in-the-management-of-markedly-elevated-blood-pressure-a-qualitative-content-analysis-of-electronic-health-records
#12
Yuan Lu, Oreoluwa Arowojolu, Xiaoliang Qiu, Yuntian Liu, Leslie Curry, Harlan M Krumholz
IMPORTANCE: Hypertension poses a significant public health challenge. Despite clinical practice guidelines for hypertension management, clinician adherence to these guidelines remains suboptimal. OBJECTIVE: This study aims to develop a taxonomy of suboptimal adherence scenarios for severe hypertension and identify barriers to guideline adherence. DESIGN: We conducted a qualitative content analysis using electronic health records (EHRs) of Yale New Haven Health System who had at least two consecutive visits between January 1, 2013, and October 31, 2018...
January 13, 2024: medRxiv
https://read.qxmd.com/read/38234772/projected-impact-of-nonpharmacologic-management-of-stage-1-hypertension-among-lower-risk-us-adults
#13
Kendra D Sims, Pengxiao Carol Wei, Joanne M Penko, Susan Hennessy, Pamela G Coxson, Nita H Mukand, Brandon K Bellows, Dhruv S Kazi, Yiyi Zhang, Ross Boylan, Andrew E Moran, Kirsten Bibbins-Domingo
BACKGROUND: The 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines newly classified 31 million US adults as having stage 1 hypertension. The ACC/AHA guidelines recommend behavioral change without pharmacology for the low-risk portion of this group. However, the nationwide reduction in cardiovascular disease (CVD) and associated healthcare expenditures achievable by evidence-based dietary improvements, sustained weight loss, adequate physical activity, and alcohol moderation remain unquantified...
December 29, 2023: medRxiv
https://read.qxmd.com/read/38230298/antihypertensive-prescribing-patterns-in-non-dialysis-dependent-chronic-kidney-disease-findings-from-the-salford-kidney-study
#14
JOURNAL ARTICLE
Rajkumar Chinnadurai, Henry H L Wu, Jones Abuomar, Sharmilee Rengarajan, David I New, Darren Green, Philip A Kalra
BACKGROUND: Hypertension is commonly observed in patients living with chronic kidney disease (CKD). Finding an optimal treatment regime remains challenging due to the complex bidirectional cause-and-effect relationship between hypertension and CKD. There remains variability in antihypertensive treatment practices. AIM: To analyze data from the Salford Kidney Study database in relation to antihypertensive prescribing patterns amongst CKD patients. METHODS: The Salford Kidney Study is an ongoing prospective study that has been recruiting CKD patients since 2002...
December 25, 2023: World Journal of Nephrology
https://read.qxmd.com/read/38212019/-review-and-prospect-of-traditional-chinese-medicine-in-treatment-of-hypertension
#15
JOURNAL ARTICLE
Xing-Jiang Xiong, Peng-Qian Wang, Kui-Wu Yao, Jing-le Hou
Hypertension, a primary cause of cardiovascular and cerebrovascular events, has become a major global public health problem and caused a heavy burden of health economics on the society. In &quot;the 20 Most Important and Most Preventable Health Problems&quot; released by the Chinese Academy of Engineering, hypertension was ranked the second. Due to the disease complexity, many hypertension patients need to take antihypertensive drugs for life. Although significant progress has been achieved in blood pressure lowering by western medicines, the problems including adverse reactions, poor compliance due to long-term medication, and ineffective mitigation in clinical symptoms related to hypertension remain to be addressed...
December 2023: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://read.qxmd.com/read/38202209/incretin-therapies-for-patients-with-type-2-diabetes-and-chronic-kidney-disease
#16
REVIEW
Radica Z Alicic, Joshua J Neumiller
Since the early 2000s, an influx of novel glucose-lowering agents has changed the therapeutic landscape for treatment of diabetes and diabetes-related complications. Glucagon-like peptide-1 (GLP-1) receptor agonists represent an important therapeutic class for the management of type 2 diabetes (T2D), demonstrating benefits beyond glycemic control, including lowering of blood pressure and body weight, and importantly, decreased risk of development of new or worsening chronic kidney disease (CKD) and reduced rates of atherosclerotic cardiovascular events...
December 29, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38189961/the-ongoing-impact-of-obesity-on-childhood-hypertension
#17
JOURNAL ARTICLE
Robert L Myette, Joseph T Flynn
Obesity rates among children have been steadily rising over the past several decades. This epidemic has been accompanied by an increase in the prevalence of childhood hypertension, with children in low- and middle-income countries being affected to the same extent as children in high-income countries. This review will examine the trends in childhood blood pressure and the relationship between excess body weight and the development of hypertension. In addition, distinct mechanisms of obesity-related hypertension will be discussed...
January 8, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38182491/safety-review-of-therapeutic-ultrasound-for-spinal-cord-neuromodulation-and-blood-spinal-cord-barrier-opening
#18
REVIEW
Rui Xu, Bradley E Treeby, Eleanor Martin
New focused ultrasound spinal cord applications have emerged, particularly those improving therapeutic agent delivery to the spinal cord via blood-spinal cord barrier opening and the neuromodulation of spinal cord tracts. One hurdle in the development of these applications is safety. It may be possible to use safety trends from seminal and subsequent works in focused ultrasound to guide the development of safety guidelines for spinal cord applications. We collated data from decades of pre-clinical studies and illustrate a clear relationship between damage, time-averaged spatial peak intensity and exposure duration...
January 4, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38180874/general-practice-pharmacist-led-antipsychotic-physical-health-monitoring-a-prospective-intervention-scoping-study
#19
JOURNAL ARTICLE
Chris F Johnson, Fiona Ingram, Fiona Thomson, Pavan Srireddy, Bhautesh D Jani, Nicola Greenlaw
BACKGROUND: People with severe mental health illness die prematurely, often due to preventable cardiometabolic disease, which can be exacerbated by antipsychotic medicines that are effective for treating mental illness. Literature demonstrates that physical health monitoring, as recommended in guidelines, for people receiving antipsychotics is substandard. Therefore, we aimed to scope the potential of a general practice clinical pharmacist (GPCP)-led multidisciplinary intervention optimising adherence to cardiometabolic monitoring guidelines and delivering polypharmacy reviews...
January 5, 2024: Family Practice
https://read.qxmd.com/read/38155893/taoist-way-of-a-balanced-exercise-training-cocktail-for-the-management-of-primary-hypertension-in-older-persons
#20
JOURNAL ARTICLE
Wensheng Xiao, Bihan Wang, Xiaorong Bai, Shouyong Tang, Yang Zhang
High blood pressure is the world's leading risk factor for mortality, affecting nearly half of the global population aged 50-79 years. Physical inactivity is one factor contributing to the prevalence of hypertension. This paper discusses a new concept for the management of hypertension in older persons. We are inclined to fade the current guidelines used in China, the United States, and Europe. Although demonstrating irrefutable benefits for blood pressure regulation, the guidelines fail to address the need to incorporate balance exercises, which are crucial for mitigating the risk of falling...
2023: Frontiers in Public Health
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