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Infection bone marrow trasplantation

R Hladun, I Badell, M González, A M Martínez, J Sánchez de Toledo, M T Olivé, M E González, I Elorza, C Díaz de Heredia
INTRODUCTION: Children with primary immunodeficiency have severe life-threatening infections and a higher prevalence of autoimmune problems, allergy and lymphoproliferative disorders. Allogenic hematopoietic stem cell transplantation has been the only potentially curative option. PATIENTS AND METHODS: Patients with primary immunodeficiency underwent allogenic stem cell transplantation in the period 1985-2011, and registered in the Spanish Working Party for Bone Marrow Transplantation in Children...
February 2015: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
Rocío Parody, Rodrigo Martino, Montserrat Rovira, Lourdes Vazquez, María José Vázquez, Rafael de la Cámara, Cristina Blazquez, Francesc Fernández-Avilés, Enric Carreras, Miguel Salavert, Isidro Jarque, Carmen Martín, Francisco Martínez, Javier López, Antonio Torres, Jorge Sierra, Guilllermo F Sanz
We evaluated the occurrence of severe infections in 192 consecutive adult recipients of volunteer unrelated donor allogeneic hematopoietic stem cell transplants, with a detailed analysis of severe infections after receipt of cord blood transplants (CBTs; n = 48) or bone marrow transplants (BMTs)/peripheral blood stem cell transplants (PBSCTs; n = 144). At a 3-year median follow-up, CBT recipients had a higher risk of developing any severe infection (85% versus 69% in BMT/PBSCT recipients, P < .01). CBT recipients had a higher incidence of severe bacterial infections before day +100, but at 3 years the risks of these and other infections were similar in the CBT and BMT/PBSCT groups...
July 2006: Biology of Blood and Marrow Transplantation
E Carreras, J F Tomás, G Sanz, A Iriondo, C Boqué, J López, R Cabrera, A Sureda, V G de Soria, J Sierra, M A Sanz, A Torres
BACKGROUND AND OBJECTIVE: To analyze the results of unrelated bone marrow transplantation (UDBMT) as treatment for chronic myeloid leukemia (CML) in Spain. DESIGN AND METHODS: Eighty-seven consecutive UDBMT performed in 9 centers between October 1989 and February 1998 were evaluated. This represents more than 95% of UDBMT for CML performed in adult transplant centers in Spain during this period. The patients' median age was 31.5 years (range, 12-49). The median interval from CML diagnosis to UDBMT was 30 months (range, 3-160)...
May 2000: Haematologica
S Zhu, S Chen, H Wei, J Suo
After the transplantation of bone marrow, patients with leukemia are easily infected by kinds of microorganism and die. In this paper, F-mice with the 60Co-gamma irradiation (maximum lethal dose) were transplanted bone marrow, then control the microorganism in the environment. Morever the laminar flow wards for the leukemia patient of bone marrow transplantation were designed according to the data combined with the clinic condition. There is no any infection in twelve patients with bone marrow transplantation from 1989 to 1993...
April 1997: Wei Sheng Wu Xue Bao, Acta Microbiologica Sinica
I Badell, J J Ortega, A Muñoz, E Bureo, L Madero, T Olivé, J Cubells, M S Maldonado, J Baro, M A Díaz
PURPOSE: Using the data from the GETMON ("Grupo Español de Trasplante de Medula Osea en Niños") we carried out a retrospective analysis of the results of allogeneic bone marrow transplantation (alloBMT) compared to autologous bone marrow transplantation (ABMT) in 113 paediatric patients with acute lymphoblastic leukaemia (ALL) in second remission. Transplants were performed by the following centers, from April 1983 to December 1991: H. Vall d'Hebrón and H. Sant Pau from Barcelona, H...
April 1996: Sangre
E León, R Sosa
The first case of allogeneic bone marrow transplantation in acute myelogenous leukemia (AML) done in Mexico is reported. The patient was a 26 year old Mexican woman who in October 1987 was diagnosed of having AML of the M2 subtype. After three cycles of the TADOP regimen (6-thioguanine, cytosine-arabinoside, doxorubicin, vincristine & prednisone), the patient entered complete remission. Unfortunately, after a seven month period of remission she suffered a relapse which was refractory to a new chemotherapy cycle...
July 1992: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
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