keyword
https://read.qxmd.com/read/37221069/-analysis-of-on-demand-adherence-and-related-factors-in-men-who-have-sex-with-men-who-access-hiv-pre-exposure-prophylaxis-services-via-the-internet
#1
JOURNAL ARTICLE
Q Z Liu, X Yang, H Xue, H L Tang
Objective: To understand the compliancy to on-demand HIV pre-exposure prophylaxis (PrEP) and related factors in men who have sex with men (MSM) accessing to PrEP service through an Internet platform. Methods: A cross-sectional study method was used to recruit survey respondents through the Heer Health platform from July 6 to August 30, 2022, and a questionnaire survey on the current status of medication use was conducted in MSM who use PrEP through the platform and take medication on demand. The MSM's information collected in the survey mainly included socio-demographic characteristics, behavioral characteristics, risk perception characteristics, PrEP awareness and the status of dose taking...
May 10, 2023: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://read.qxmd.com/read/36716726/long-term-clinical-course-after-successful-initial-treatment-in-patients-with-mild-erosive-esophagitis-a-prospective-follow-up-study
#2
JOURNAL ARTICLE
Hideharu Okanobu, Tomohiko Kohno, Kazuki Boda, Hidenori Ochi, Yoshinari Furukawa
INTRODUCTION: This study aimed to investigate the clinical course of patients with healed mild erosive esophagitis and clarify the predictive factors for continuous treatment. METHOD: Fifty-one patients with mild erosive esophagitis who confirmed mucosal healing by endoscopy after initial treatment with vonoprazan (VPZ) were enrolled. The patients continued subsequent treatment of their choice: maintenance therapy with VPZ 10 mg (n = 15), on-demand therapy with VPZ 20 mg (n = 19), or no medication (n = 17)...
January 30, 2023: Digestion
https://read.qxmd.com/read/33807390/production-of-reproducible-filament-batches-for-the-fabrication-of-3d-printed-oral-forms
#3
JOURNAL ARTICLE
Stéphane Roulon, Ian Soulairol, Valérie Lavastre, Nicolas Payre, Maxime Cazes, Laurent Delbreilh, Jean Alié
Patients need medications at a dosage suited to their physiological characteristics. Three-dimensional printing (3DP) technology by fused-filament fabrication (FFF) is a solution for manufacturing medication on demand. The aim of this work was to identify important parameters for the production of reproducible filament batches used by 3DP for oral formulations. Amiodarone hydrochloride, an antiarrhythmic and insoluble drug, was chosen as a model drug because of dosage adaptation need in children. Polyethylene oxide (PEO) filaments containing amiodarone hydrochloride were produced by hot-melt extrusion (HME)...
March 31, 2021: Pharmaceutics
https://read.qxmd.com/read/33705475/providing-open-label-placebos-remotely-a-randomized-controlled-trial-in-allergic-rhinitis
#4
JOURNAL ARTICLE
Tobias Kube, Verena E Hofmann, Julia A Glombiewski, Irving Kirsch
BACKGROUND: Placebos can reduce physical symptoms even when provided with full honesty and disclosure. Yet, the precise mechanisms underlying the effects of "open-label placebos" (OLPs) have remained subject of debate. Furthermore, it is unclear whether OLPs are similarly effective when provided remotely, as is sometimes required e.g. in the current COVID-19 pandemic. METHODS: In a randomized-controlled trial, we examined the effects of OLP plus treatment as usual (TAU) compared to TAU alone on symptom reduction in people with allergic rhinitis (N = 54) over the course of two weeks...
2021: PloS One
https://read.qxmd.com/read/30737102/design-and-testing-of-medivate-a-mobile-app-to-achieve-medication-list-portability-via-fast-healthcare-interoperability-resources
#5
JOURNAL ARTICLE
James C Coons, Ravi Patel, Kim C Coley, Philip E Empey
OBJECTIVES: To describe the architecture, design, and testing of an innovative mobile application (Medivate) that facilities accurate sharing of medication lists with linked education. SETTING: The deployment and testing of this app occurred in both the community and hospital settings in Pittsburgh, PA. PRACTICE INNOVATION: Medivate is an iOS smartphone application and cloud architecture for patients and providers to keep medication and vaccine lists accurate by providing a method and tool to easily exchange these data...
February 5, 2019: Journal of the American Pharmacists Association: JAPhA
https://read.qxmd.com/read/29609566/pulsatile-dry-cupping-in-chronic-low-back-pain-a-randomized-three-armed-controlled-clinical-trial
#6
RANDOMIZED CONTROLLED TRIAL
M Teut, A Ullmann, M Ortiz, G Rotter, S Binting, M Cree, F Lotz, S Roll, B Brinkhaus
BACKGROUND: We aimed to investigate the effectiveness of two different forms of dry pulsatile cupping in patients with chronic low back pain (cLBP) compared to medication on demand only in a three-armed randomized trial. METHODS: 110 cLBP patients were randomized to regular pulsatile cupping with 8 treatments plus paracetamol on demand (n = 37), minimal cupping with 8 treatments plus paracetamol on demand (n = 36) or the control group with paracetamol on demand only (n = 37)...
April 2, 2018: BMC Complementary and Alternative Medicine
https://read.qxmd.com/read/29202811/high-prevalence-of-prescription-of-psychotropic-drugs-for-older-patients-in-a-general-hospital
#7
JOURNAL ARTICLE
Inken Arnold, Kati Straube, Wolfgang Himmel, Stephanie Heinemann, Vivien Weiss, Laura Heyden, Eva Hummers-Pradier, Roland Nau
BACKGROUND: Many elderly patients receive psychotropic drugs. Treatment with psychotropic agents is associated with serious side effects including an increased risk of falls and fractures. Several psychotropic drugs are considered potentially inappropriate for treatment of the elderly. METHODS: A retrospective chart review was conducted covering all patients aged ≥ 65 years who were admitted to Evangelisches Krankenhaus Göttingen-Weende between 01/01/2013 and 03/31/2013...
December 4, 2017: BMC Pharmacology & Toxicology
https://read.qxmd.com/read/28803262/topic-anaesthesia-with-a-eutectic-mixture-of-lidocaine-prilocaine-cream-after-elective-caesarean-section-a-randomised-placebo-controlled-trial
#8
RANDOMIZED CONTROLLED TRIAL
Thomas Grosse-Steffen, Malin Krämer, Benjamin Tuschy, Christel Weiss, Marc Sütterlin, Sebastian Berlit
PURPOSE: Aim of the study was to investigate the topical application of a eutectic mixture of lidocaine/prilocaine (EMLA® ) cream after caesarean section (CS) and its effect on postoperative pain, time to mobilisation, and time to discharge. MATERIALS AND METHODS: A total of 189 pregnant women were enrolled; full data sets were available for 139 of them, who were prospectively randomised to receive either placebo (control group) or EMLA® cream (study group) on the CS lesion directly as well as 24 h after surgery...
October 2017: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/27221231/allograft-augmentation-in-proximal-humerus-fractures
#9
JOURNAL ARTICLE
S A Euler, F S Kralinger, C Hengg, M Wambacher, M Blauth
OBJECTIVE: Achieve stable fixation to initially start full range of motion (ROM) and to prevent secondary displacement in unstable fracture patterns and/or weak and osteoporotic bone. INDICATIONS: (Secondarily) displaced proximal humerus fractures (PHF) with an unstable medial hinge and substantial bony deficiency, weak/osteoporotic bone, pre-existing psychiatric illnesses or patient incompliance to obey instructions. CONTRAINDICATIONS: Open/contaminated fractures, systemic immunodeficiency, prior graft-versus-host reaction...
June 2016: Operative Orthopädie und Traumatologie
https://read.qxmd.com/read/27176061/-bronchial-asthma-many-types-different-therapies
#10
REVIEW
Karl-Christian Bergmann
Around 9 % of the German population is affected by bronchial asthma. This serious problem diminishes the quality of life as well as performance of the patients. Triggers and individual courses of the illness are very diverse. Therapy for mild asthma (stage 1 and 2) can take place at the patient's general practitioner. Is the effect of the medication insufficient, the patient should be referred to a specialist. The aim of the therapy is controlled asthma without symptoms during day or night and patients who only rarely need medication on demand and who are not limited in their daily activities...
May 2016: Deutsche Medizinische Wochenschrift
https://read.qxmd.com/read/26229456/characteristics-of-prevalent-and-new-copd-cases-in-greece-the-golden-study
#11
JOURNAL ARTICLE
Eirini Mitsiki, Eleni Bania, Christos Varounis, Konstantinos I Gourgoulianis, Evangelos C Alexopoulos
BACKGROUND: Greece has one of the highest rates of smoking and chronic obstructive pulmonary disease (COPD) in Europe. AIM: The study aimed to record both the disease characteristics among a sample of Greek COPD patients and the nationwide rates of newly diagnosed COPD cases. METHODS: In this noninterventional, epidemiological cross-sectional study, a representative nationwide sample of 45 respiratory centers provided data on the following: 1) the demographic and clinical characteristics of COPD patients and 2) newly diagnosed COPD cases monitored over a period of 6 months by each physician...
2015: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/25216962/topical-anaesthetic-patches-for-postoperative-wound-pain-in-laparoscopic-gynaecological-surgery-a-prospective-blinded-and-randomised-trial
#12
RANDOMIZED CONTROLLED TRIAL
Sebastian Berlit, Benjamin Tuschy, Joachim Brade, Franz Hüttner, Amadeus Hornemann, Marc Sütterlin
PURPOSE: Aim of this prospective study was to investigate the effectiveness of eutectic mixture of local anaesthetic (EMLA) patches on every abdominal incision for pain relief after gynaecologic laparoscopic surgery. METHODS: A total of 121 women were prospectively randomised to receive either placebo (control group) or EMLA (study group) patches on all abdominal incisions. Postoperative pain was assessed 24 and 48 h after surgery using the short form of the McGill Pain Questionnaire (SF-MPQ)...
March 2015: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/25170361/the-contribution-of-a-clinical-pharmacist-to-the-improvement-of-medication-at-a-geriatric-hospital-unit-in-norway
#13
JOURNAL ARTICLE
Turid Veggeland, Sigurd Dyb
UNLABELLED: The aim of the study was to use a clinical pharmacist in order to improve the medication of patients in a geriatric hospital unit. The hospital had no experience of using a clinical pharmacist before. METHODS: A clinical pharmacist participated in the therapeutic team for 27 days during a 4-year period. Drug-related problems were recorded prospectively and discussed before and at the ward round. The results of the physician's decisions on the current day about potential changes in medication proposed by the pharmacist were continuously recorded...
January 2008: Pharmacy Practice
https://read.qxmd.com/read/24784890/preoperative-erectile-function-is-the-only-predictor-of-the-use-of-a-high-number-of-phosphodiesterase-type-5-inhibitors-after-bilateral-nerve-sparing-radical-prostatectomy
#14
JOURNAL ARTICLE
G Gandaglia, A Gallina, N Suardi, F Abdollah, N Passoni, M Bianchi, E Zaffuto, A Nini, D Vizziello, A Salonia, F Montorsi, A Briganti
It is well known that the administration of phosphodiesterase type-5 inhibitors (PDE5-Is) may improve erectile function (EF) recovery after bilateral nerve-sparing radical prostatectomy (BNSRP). The aim of our study was to identify predictors of the use of a high number of PDE5-Is (one or more per week) after surgery among 184 patients taking proerectile medications on demand. At a mean follow-up of 22.7 months, 116 patients (63%) recovered EF. Overall, EF recovery rates at 1- and 2- year follow-up were 47...
November 2014: International Journal of Impotence Research
https://read.qxmd.com/read/23053062/can-on-demand-non-sedating-antihistamines-improve-urticaria-symptoms-a-double-blind-randomized-single-dose-study
#15
RANDOMIZED CONTROLLED TRIAL
Karsten Weller, Elena Ardelean, Elisabeth Scholz, Peter Martus, Torsten Zuberbier, Marcus Maurer
Non-sedating H1-antihistamines are the recommended first-line treatment for chronic spontaneous urticaria. While efficacy studies usually apply continuous daily treatment regimens, many patients take their medication on demand. In this randomized, double-blind trial we tested whether on-demand H1-antihistamine desloratadine in standard and higher doses is able to improve the resolution of existing wheals. Symptoms of 29 patients with chronic spontaneous urticaria were followed without treatment on one day and again on another day during the next 3 weeks after a single dose of either 5 mg or 20 mg desloratadine, using different objective measures...
March 27, 2013: Acta Dermato-venereologica
https://read.qxmd.com/read/19284433/restraint-use-among-nursing-home-residents-cross-sectional-study-and-prospective-cohort-study
#16
JOURNAL ARTICLE
Gabriele Meyer, Sascha Köpke, Burkhard Haastert, Ingrid Mühlhauser
AIMS AND OBJECTIVES: To investigate (1) the prevalence of physical restraints and psychoactive medication, (2) newly administered physical restraints, frequency of application of the devices and frequency of psychoactive medication on demand during 12-month follow-up and (3) characteristics associated with restraint use in nursing homes. BACKGROUND: High quality data on restraint use in German nursing homes are lacking so far. Such information is the basis for interventions to achieve a restraint-free care...
April 2009: Journal of Clinical Nursing
https://read.qxmd.com/read/18415237/-postoperative-analgesia-with-buprenorphine-a-comparative-study-of-epidural-patient-controlled-intravenous-and-conventional-subcutaneous-administration
#17
JOURNAL ARTICLE
J Fähnrich, C Castelano, E Sturzenegger, B Stoll, P Uehlinger, S Geroulanos
Thirty patients who had undergone elective anterolateral thoracotomy were studied in the surgical intensive care unit to compare the analgesic effectiveness of i.v. self-administered buprenorphine (group A) with that of epidural administration (group B) and of s.c. administration by a nurse of 0.3 mg buprenorphine every 3-4 h (group C, controls). Every 2 h the patients were asked to record their subjektive pain level as a percentage on an analogue scale: zero was to be used for no pain and 100% for the most severe pain they could imagine...
December 1990: Der Schmerz
https://read.qxmd.com/read/17066860/-postoperative-pain-management-in-a-tertiary-care-hospital-initial-situation-prior-to-starting-a-quality-assurance-program
#18
JOURNAL ARTICLE
B Valentín López, J García Caballero, J M Muñoz Ramón, P Aparicio Grande, J Díez Sebastán, A Criado Jiménez
OBJECTIVE: To characterize the initial situation in postoperative pain management among the services General and Vascular surgery as the first step in developing a program to improve postoperative analgesia. METHODS: An anonymous questionnaire with 14 items covered the characteristics of postoperative pain, information received about analgesic treatments and requesting medication, and degree of satisfaction. The questionnaire was filled in during an early postoperative interview with all patients undergoing surgery in the aforementioned departments...
August 2006: Revista Española de Anestesiología y Reanimación
https://read.qxmd.com/read/16113546/on-demand-therapy-with-pantoprazole-20-mg-as-effective-long-term-management-of-reflux-disease-in-patients-with-mild-gerd-the-orion-trial
#19
RANDOMIZED CONTROLLED TRIAL
T Scholten, C P M Dekkers, K Schütze, T Körner, M Bohuschke, G Gatz
AIMS: To compare safety and efficacy of on-demand pantoprazole 20 mg/40 mg versus placebo in the long-term management of patients with mild gastroesophageal reflux disease (GERD) after heartburn relief. METHODS: A total of 634 patients with endoscopically confirmed GERD grade 0/I and heartburn were included. During the acute phase, patients were treated with pantoprazole 20 mg once daily for 4 weeks. Those patients relieved from heartburn entered the long-term phase, and were randomly assigned to either treatment group pantoprazole 20 mg, 40 mg or placebo...
2005: Digestion
https://read.qxmd.com/read/15370793/use-of-prescribed-and-non-prescribed-medication-for-dyspepsia
#20
JOURNAL ARTICLE
Nicole Krol, Jean W M Muris, Geert Schattenberg, Richard Grol, Michel Wensing
OBJECTIVE: To explore patient factors related to the use of prescribed and non-prescribed drugs for dyspepsia in The Netherlands. DESIGN: Patient survey study. SETTING AND SUBJECTS: Questionnaires sent to patients who had a prescription for dyspepsia medication from their general practitioner. MAIN OUTCOME MEASURES: Patient factors related to the on-demand use of prescribed medication and the use of non-prescribed medication for dyspepsia...
September 2004: Scandinavian Journal of Primary Health Care
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