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Cognition AND Depression

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https://www.readbyqxmd.com/read/29166674/unpredictable-chronic-mild-stress-differentially-impairs-social-and-contextual-discrimination-learning-in-two-inbred-mouse-strains
#1
Michiel van Boxelaere, Jason Clements, Patrick Callaerts, Rudi D'Hooge, Zsuzsanna Callaerts-Vegh
Alterations in the social and cognitive domain are considered important indicators for increased disability in many stress-related disorders. Similar impairments have been observed in rodents chronically exposed to stress, mimicking potential endophenotypes of stress-related psychopathologies such as major depression disorder (MDD), anxiety, conduct disorder, and posttraumatic stress disorder (PTSD). Data from numerous studies suggest that deficient plasticity mechanisms in hippocampus (HC) and prefrontal cortex (PFC) might underlie these social and cognitive deficits...
2017: PloS One
https://www.readbyqxmd.com/read/29166356/factors-related-to-different-objects-of-awareness-in-alzheimer-disease
#2
Isabel B Lacerda, Raquel L Santos, José Pedro Simões Neto, Marcia C N Dourado
Awareness of deficits is a multidimensional phenomenon described as the ability to acknowledge difficulties and impairments. We investigated whether unawareness affects distinct domains to different degrees and identified the factors related to the awareness impairment in Alzheimer Disease (AD). Using a cross-sectional design, we assessed 89 people with AD (PwAD) and their caregivers. Awareness was evaluated by scoring discrepant responses between PwAD and their caregivers across domains including cognitive functioning and health condition, functional activity impairments, emotional state, social functioning, and interpersonal relationships...
October 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/29166250/differences-by-sex-in-association-of-mental-health-with-video-gaming-or-other-nonacademic-computer-use-among-us-adolescents
#3
Hogan H Lee, Jung Hye Sung, Ji-Young Lee, Jae Eun Lee
INTRODUCTION: Although numerous studies have examined the association between playing video games and cognitive skills, aggression, and depression, few studies have examined how these associations differ by sex. The objective of our study was to determine differences by sex in association between video gaming or other nonacademic computer use and depressive symptoms, suicidal behavior, and being bullied among adolescents in the United States. METHODS: We used data from the 2015 Youth Risk Behavior Survey on 15,624 US high school students...
November 22, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29165720/-relationship-strain-parkinson-s-disease-gender-specific-distress-of-partners-of-patients-with-parkinson-s-disease
#4
Christoph Braukhaus, Uwe Jahnke, Tanja Zimmermann
A Parkinson's disease is attended by high strain for the patients and an obvious loss of relationship functioning. Partners of patients (N=110) were evaluated via self-assessment in terms of own depression (PHQ-9), own fear of progression (PA-F-P-KF), relationship quality (PFB) as well as perceived deficits in everyday life and nonverbal communication. 26% of women and 11% of men showed depression scores, 51% of women and 41% of men dysfunctional fear of progression and about 60% were unsatisfied with their relationship...
November 17, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29165083/subjective-spatial-navigation-complaints-a-frequent-symptom-reported-by-patients-with-subjective-cognitive-decline-mild-cognitive-impairment-and-alzheimer-s-disease
#5
Cerman Jiri, Andel Ross, Laczo Jan, Vyhnalek Martin, Nedelska Zuzana, Mokrisova Ivana, Sheardova Katerina, Hort Jakub
BACKGROUND: Great effort has been put into developing simple and feasible tools capable to detect Alzheimer's disease (AD) in its early clinical stage. Spatial navigation impairment occurs very early in AD and is detectable even in the stage of mild cognitive impairment (MCI). OBJECTIVE: The aim was to describe the frequency of self-reported spatial navigation complaints in patients with subjective cognitive decline (SCD), amnestic and non-amnestic MCI (aMCI, naMCI) and AD dementia and to assess whether a simple questionnaire based on these complaints may be used to detect early AD...
November 20, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/29165000/building-better-caregivers-a-pragmatic-12-month-trial-of-a-community-based-workshop-for-caregivers-of-cognitively-impaired-adults
#6
Kate Lorig, Philip L Ritter, Diana D Laurent, Veronica Yank
Building Better Caregivers (BBC), a community 6-week, peer-led intervention, targets family caregivers of those with cognitive impairments. BBC was implemented in four geographically scattered areas. Self-report data were collected at baseline, 6 months, and 1 year. Primary outcome were caregiver strain and depression. Secondary outcomes included caregiver burden, stress, fatigue, pain, sleep, self-rated health, exercise, self-efficacy, and caregiver and care partner health care utilization. Paired t tests examined 6 month and 1-year improvements...
November 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/29164970/a-feasibility-study-of-trauma-sensitive-obstetric-care-for-low-income-ethno-racial-minority-pregnant-abuse-survivors
#7
N R Stevens, T A Lillis, L Wagner, V Tirone, S E Hobfoll
PURPOSE: This study evaluated the feasibility and acceptability of an integrated (psychological and obstetric) intervention for pregnant abuse survivors with posttraumatic stress symptoms (PTS) from low-income, ethno-racial minority backgrounds. METHODS: Trauma-sensitive obstetrics to promote control, anxiety-reduction and empowerment (TO-CARE) offers cognitive-behavioral therapy (CBT) coping skills delivered over six sessions by therapists, coupled with trauma-sensitive obstetric care from specially-trained obstetric physicians...
November 22, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29164776/nutritional-screening-and-dietitian-consultation-rates-in-a-geriatric-evaluation-and-management-unit
#8
Elsa Dent, Olivia Wright, Emiel O Hoogendijk, Ruth E Hubbard
AIM: Nutritional screening may not always lead to intervention. The present study aimed to determine: (i) the rate of nutritional screening in hospitalised older adults; (ii) whether nutritional screening led to dietitian consultation and (iii) factors associated with malnutrition. METHODS: In this prospective study of patients aged ≥70 years admitted to a Geriatric Evaluation and Management Unit (GEMU), malnutrition was screened for using the Mini Nutritional Assessment Short Form (MNA-SF) and identified using the Mini Nutritional Assessment (MNA)...
November 22, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29164609/who-benefits-from-adolescent-sleep-interventions-moderators-of-treatment-efficacy-in-a-randomized-controlled-trial-of-a-cognitive-behavioral-and-mindfulness-based-group-sleep-intervention-for-at-risk-adolescents
#9
Matthew J Blake, Laura M Blake, Orli Schwartz, Monika Raniti, Joanna M Waloszek, Greg Murray, Julian G Simmons, Elizabeth Landau, Ronald E Dahl, Dana L McMakin, Paul Dudgeon, John Trinder, Nicholas B Allen
BACKGROUND: The aim of this study was to test moderators of therapeutic improvement in an adolescent cognitive-behavioral and mindfulness-based group sleep intervention. Specifically, we examined whether the effects of the program on postintervention sleep outcomes were dependent on participant gender and/or measures of sleep duration, anxiety, depression, and self-efficacy prior to the interventions. METHOD: Secondary analysis of a randomized controlled trial conducted with 123 adolescent participants (female = 59...
November 22, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29164561/study-of-prevalence-and-influencing-factors-of-depression-in-tumor-patients-and-the-therapeutic-effects-of-fluoxetine
#10
J Dai, N Liao, J Shi, J-Q Tao
OBJECTIVE: To observe the depression in patients with malignant tumor and influencing factors of the disease, as well as to investigate the effects of fluoxetine on depressive symptoms in cancer patients and the immune function. PATIENTS AND METHODS: 262 patients with malignant tumors, confirmed by pathological and radiological diagnosis as malignant tumor were randomly divided into 2 groups: the control group with chemotherapy; the treatment group with chemotherapy and 20 mg/d fluoxetine for six weeks...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29164499/cognitive-disparities-the-impact-of-the-great-depression-and-cumulative-inequality-on-later-life-cognitive-function
#11
Jo Mhairi Hale
Population aging has driven a spate of recent research on later-life cognitive function. Greater longevity increases the lifetime risk of memory diseases that compromise the cognitive abilities vital to well-being. Alzheimer's disease, thought to be the most common underlying pathology for elders' cognitive dysfunction (Willis and Hakim 2013), is already the sixth leading cause of death in the United States (Alzheimer's Association 2016). Understanding social determinants of pathological cognitive decline is key to crafting interventions, but evidence is inconclusive for how social factors interact over the life course to affect cognitive function...
November 21, 2017: Demography
https://www.readbyqxmd.com/read/29164126/overweight-and-cognitive-performance-high-body-mass-index-is-associated-with-impairment-in-reactive-control-during-task-switching
#12
Laura Steenbergen, Lorenza S Colzato
The prevalence of weight problems is increasing worldwide. There is growing evidence that high body mass index (BMI) is associated with frontal lobe dysfunction and deficits in cognitive control. The present study aims to clarify the association between weight status and the degree of impairment in cognitive flexibility, i.e., the ability to efficiently switch from one task to another, by disentangling the preparatory and residual domains of task switching. Twenty-six normal weight (BMI < 25, five males) and twenty-six overweight (BMI ≥ 25, seven males) university students performed a task-switching paradigm that provides a relatively well-established diagnostic measure of proactive vs...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29164115/cross-sectional-associations-of-fatigue-with-cerebral-%C3%AE-amyloid-in-older-adults-at-risk-of-dementia
#13
Claudie Hooper, Philipe De Souto Barreto, Nicola Coley, Matteo Cesari, Pierre Payoux, Anne Sophie Salabert, Sandrine Andrieu, Bruno Vellas
Fatigue is a common symptom in the elderly and has also been associated with impaired cognition in older adults. Hence, we sought to explore the cross-sectional relationship between fatigue and cerebral β-amyloid (Aβ) in 269 elderly individuals reporting subjective memory complaints from the Multidomain Alzheimer Preventive Trial. Standard uptake value ratios (SUVRs) were generated by [(18)F] florbetapir positron emission tomography (PET) using the cerebellum as a reference. Cortical-to-cerebellar SUVRs (cortical-SUVRs) were obtained using the mean signal from the frontal cortex, temporal cortex, parietal cortex, precuneus, anterior cingulate, and posterior cingulate...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29164042/different-effects-of-cognitive-and-non-exercise-physical-leisure-activities-on-cognitive-function-by-age-in-elderly-korean-individuals
#14
Mi Sook Jung, Hyunli Kim, Yeji Lee, Mijung Kim, Eunyoung Chung
Objectives: We aimed to examine the effects of various leisure activities on cognitive impairment in young-old (aged 65-74 years) and old-old (aged ≥ 75 years) adults. Methods: In total, 10,279 elderly Korean individuals from the 2014 Korean National Survey on Older Adults' cohort were enrolled in our study. Cognitive impairment was assessed using the standardized score of the Mini-Mental State Examination for Dementia Screening, whereas leisure activities were recorded via self-reporting of the extent and type of leisure activity the subjects involved in over the past year...
October 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/29163868/the-effectiveness-of-psychosocial-interventions-in-war-traumatized-refugee-and-internally-displaced-minors-systematic-review-and-meta-analysis
#15
REVIEW
Agnes Nocon, Rima Eberle-Sejari, Johanna Unterhitzenberger, Rita Rosner
Background: The United Nations reported that in 2016 over 65 million people worldwide have forcibly left home. Over 50% are children and adolescents; a substantial number has been traumatized and displaced by war. Objective: To provide an overview of the effectiveness of psychosocial interventions in this group we conducted a narrative review and a meta-analysis of intervention studies providing data on posttraumatic stress symptoms (PTSS), depression, anxiety, grief, and general distress. Method: We searched PILOTS, MEDLINE, WoS, Embase, CENTRAL, LILACS, PsycINFO, ASSIA, CSA, and SA for studies on treatment outcomes for war-traumatized displaced children and adolescents...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29163863/cognitive-therapy-and-eye-movement-desensitization-and-reprocessing-for-reducing-psychopathology-among-disaster-bereaved-individuals-study-protocol-for-a-randomized-controlled-trial
#16
Lonneke I M Lenferink, Eline Piersma, Jos de Keijser, Geert E Smid, Paul A Boelen
Background: Confrontation with a traumatic (e.g. disaster-related) loss is a risk factor for the development of psychopathology, including symptoms of prolonged grief (PG), posttraumatic stress (PTS), and depression. Although interventions have been developed for reducing post-loss psychopathology, more research into the effectiveness of treatment is needed to improve care for bereaved persons. Cognitive therapy (CT) and eye movement desensitization and reprocessing (EMDR) have been shown to be effective in trauma-exposed populations...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29163737/the-mechanisms-underlying-changes-in-broad-dimensions-of-psychopathology-during-cognitive-behavioral-therapy-for-social-anxiety-disorder
#17
Sei Ogawa, Risa Imai, Masako Suzuki, Toshi A Furukawa, Tatsuo Akechi
Background: Social anxiety disorder (SAD) patients commonly have broad dimensions of psychopathology. This study investigated the relationship between a wide range of psychopathology and attention or cognitions during cognitive behavioral therapy (CBT) for SAD. Methods: We treated 96 SAD patients with group CBT. Using multiple regression analysis, we examined the associations between the changes in broad dimensions of psychopathology and the changes in self-focused attention or maladaptive cognitions in the course of CBT...
December 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29163328/parkinson-s-disease-severity-at-3%C3%A2-years-can-be-predicted-from-non-motor-symptoms-at-baseline
#18
Alba Ayala, José Matías Triviño-Juárez, Maria João Forjaz, Carmen Rodríguez-Blázquez, José-Manuel Rojo-Abuin, Pablo Martínez-Martín
Objective: The aim of this study is to present a predictive model of Parkinson's disease (PD) global severity, measured with the Clinical Impression of Severity Index for Parkinson's Disease (CISI-PD). Methods: This is an observational, longitudinal study with annual follow-up assessments over 3 years (four time points). A multilevel analysis and multiple imputation techniques were performed to generate a predictive model that estimates changes in the CISI-PD at 1, 2, and 3 years...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29163162/a-randomized-double-blinded-clinical-trial-on-effects-of-a-vitis-vinifera-extract-on-cognitive-function-in-healthy-older-adults
#19
Gioacchino Calapai, Francesco Bonina, Andrea Bonina, Luisa Rizza, Carmen Mannucci, Vincenzo Arcoraci, Germana Laganà, Angela Alibrandi, Concetta Pollicino, Santi Inferrera, Umberto Alecci
Introduction: Gradual population aging is creating a new set of needs in the general population. Memory capacity decreases with age, and memory deficits are considered an early symptom of Alzheimer's Disease (AD), one of the most prevalent cognitive disorders in older people. Numerous studies have shown that grape polyphenolic compounds (GPs) are able to attenuate cognitive impairment and reduce brain lesions in experimental AD animal models. These GP effects are associated with improvement in brain antioxidant status and prevention of free radical-induced neuronal damage...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29163137/multiple-evidences-for-association-between-cognitive-impairment-and-dysglycemia-in-parkinson-s-disease-implications-for-clinical-practice
#20
Liu Yang, Zhilin Chen, Bo Li, Meihua Wang, Lijia Yu, Ying Wan, Jing Gan, Yu Zhang, Zhenguo Liu, Xijin Wang
Background and purpose: It remains unclear about the etiopathogenesis of cognitive impairment (CI) in Parkinson's disease (PD). Since diabetes mellitus (DM) has been shown to be associated with CI in several diseases, we examined the association between CI and dysglycemia in PD. Methods: Enrolled PD patients completed a series of clinical and neuropsychological assessments. Motor symptoms were determined by Hohen-Yahr staging (H-Y staging) and Unified Parkinson's Disease Rating Scale - motor score (UPDRS-III)...
2017: Frontiers in Aging Neuroscience
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