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https://www.readbyqxmd.com/read/29145613/commentary-on-do-not-fear-an-implant-s-shape-a-single-surgeon-s-experience-of-over-1200-round-and-shaped-textured-implants-in-primary-breast-augmentation
#1
Jamil Ahmad, Frank Lista
No abstract text is available yet for this article.
November 14, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29137219/functional-characterization-of-lysine-specific-demethylase-2-lsd2-kdm1b-in-breast-cancer-progression
#2
Lin Chen, Shauna N Vasilatos, Ye Qin, Tiffany A Katz, Chunyu Cao, Hao Wu, Nilgun Tasdemir, Kevin M Levine, Steffi Oesterreich, Nancy E Davidson, Yi Huang
Flavin-dependent histone demethylases govern histone H3K4 methylation and act as important chromatin modulators that are extensively involved in regulation of DNA replication, gene transcription, DNA repair, and heterochromatin gene silencing. While the activities of lysine-specific demethylase 1 (LSD1/KDM1A) in facilitating breast cancer progression have been well characterized, the roles of its homolog LSD2 (KDM1B) in breast oncogenesis are relatively less understood. In this study, we showed that LSD2 protein level was significantly elevated in malignant breast cell lines compared with normal breast epithelial cell line...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29131778/adventures-and-misadventures-in-plastic-surgery-and-soft-tissue-implants
#3
Dana J Lin, Tony T Wong, Gina A Ciavarra, Jonathan K Kazam
Soft-tissue augmentation and implants are increasingly seen by the radiologist as more techniques emerge for a variety of indications and locations. Some surgical and implant procedures are performed for purely cosmetic reasons in otherwise healthy patients seeking to improve their body image, and some are performed for reconstruction after cancer or other chronic illnesses. Abdominoplasty, liposuction, and autologous fat grafting can be performed for abdominal and gluteal contouring. Injection of liquid injectable silicone has historically been fraught with legal issues, although it continues to be used for augmentation in a variety of anatomic locations...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29124375/reductive-augmentation-of-the-breast
#4
Paul E Chasan
AIM: Although breast reduction surgery plays an invaluable role in the correction of macromastia, it almost always results in a breast lacking in upper pole fullness and/or roundness. We present a technique of breast reduction combined with augmentation termed "reductive augmentation" to solve this problem. The technique is also extremely useful for correcting breast asymmetry, as well as revising significant pseudoptosis in the patient who has previously undergone breast augmentation with or without mastopexy...
November 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29124374/complications-and-treatment-strategy-after-breast-augmentation-by-polyacrylamide-hydrogel-injection-summary-of-10-year-clinical-experience
#5
Rui Jin, Xusong Luo, Xiaoke Wang, Jie Ma, Fei Liu, Qun Yang, Jun Yang, Xi Wang
From 1997 to 2006, polyacrylamide hydrogel (PAAG) was approved for use in China as a permanent filler for breast augmentation, and it is estimated that 200,000 women have undergone PAAG injection since then. After injection, complications such as pain, mass, hematoma, asymmetry, migration, infection, and even cancer continue to emerge. Because of the potential toxicity and unstable nature of the material and the nonstandardized injection layers, complications after PAAG injection breast augmentation are often complex and difficult to treat...
November 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29124373/-the-chignon-mastopexy-a-double-glandular-suspended-flaps-for-an-auto-augmentation-effect
#6
Bouraoui Kotti
BACKGROUND: Many mastopexy techniques have been described in the literature focusing on the new nipple areolar complex position and the breast deflation treatment, but only few of them detailed the glandular volume redistribution to avoid the use of implants. We describe a mastopexy procedure that brings the maximum of the volume to the central part of the breast. We compare the procedure to a "chignon" hair style way to vulgarize the technique and simplify its comprehension. METHODS: Breast volume is reshaped by the use of a vertical mastopexy and two deepithelized glandular flaps sutured for the first one to the pectoralis major fascia and for the second one to the contralateral flap...
November 9, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29106482/do-not-fear-an-implant-s-shape-a-single-surgeon-s-experience-of-over-1200-round-and-shaped-textured-implants-in-primary-breast-augmentation
#7
Paolo Montemurro, Mubashir Cheema, Per Hedén, Mouchammed Agko, Alessandro Quattrini Li, Stefano Avvedimento
Background: Breast implants can be characterized by their fill material, surface texture, or shape. Whereas long-term good quality studies have provided evidence for the fill material and texture, there is still little consensus for choosing the shape of an implant. Surveys indicate that many surgeons choose only one implant shape, for reasons that may not always agree with outcomes from long-term studies. Objectives: We reviewed the first author's experience over the last six years with both round and anatomical implants, compared the rate of complications with either implant shape, and discussed the importance of keeping an open mind about using both implant shapes for primary breast augmentation...
August 9, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29106472/commentary-on-current-trends-in-breast-augmentation-an-international-analysis
#8
Mitchell H Brown
No abstract text is available yet for this article.
July 4, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29101436/anaplastic-large-cell-lymphoma-associated-with-breast-implants-a-case-report-of-a-transgender-female
#9
Matej Patzelt, Lucie Zarubova, Pavel Klener, Josef Barta, Kamila Benkova, Adrianna Brandejsova, Marek Trneny, Robert Gürlich, Andrej Sukop
Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a rare peripheral T cell lymphoma. BIA-ALCL is a disease of the fibrous capsule surrounding the implant and occurs in patients after both breast reconstruction and augmentation. More than 300 cases have been reported so far, including two in a transgender patient. Here we describe BIA-ALCL presented with a mass in a transgender patient and the first case of BIA-ALCL in the Czech Republic. In 2007, a 33-year-old transgender male to female underwent bilateral breast augmentation as a part of his transformation to female...
November 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29095048/equol-enhances-apoptosis-inducing-activity-of-genistein-by-increasing-bax-bcl-xl-expression-ratio-in-mcf-7-human-breast-cancer-cells
#10
Misaki Ono, Kaoru Ejima, Takako Higuchi, Mikako Takeshima, Rei Wakimoto, Shuji Nakano
Anticancer activities of soy isoflavones, such as genistein and equol, a bioactive metabolite of daidzein, have been extensively studied because of possible involvement in the prevention of breast cancer. However, their interactions still remain unclear. We investigated here whether cytotoxic activity of genistein was enhanced by equol, using estrogen receptor positive MCF-7, HER2-positive SK-BR-3, and triple-negative MDA-MB-468 cell lines. Although cytotoxicity of genistein did not significantly differ between three subtypes of breast cancer cells, cytotoxic activities of genistein were significantly enhanced in combination with 50 μM equol in MCF-7 cells, but not in SK-BR-3 and MDA-MB-468 cells...
November 2, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/29089892/is-there-an-opportunity-for-current-chemotherapeutics-to-up-regulate-mic-a-b-ligands
#11
Kendel Quirk, Shanmugasundaram Ganapathy-Kanniappan
Natural killer (NK) cells are critical effectors of the immune system. NK cells recognize unhealthy cells by specific ligands [e.g., MHC- class I chain related protein A or B (MIC-A/B)] for further elimination by cytotoxicity. Paradoxically, cancer cells down-regulate MIC-A/B and evade NK cell's anticancer activity. Recent data indicate that cellular-stress induces MIC-A/B, leading to enhanced sensitivity of cancer cells to NK cell-mediated cytotoxicity. In this Perspective article, we hypothesize that current chemotherapeutics at sub-lethal, non-toxic dose may promote cellular-stress and up-regulate the expression of MIC-A/B ligands to augment cancer's sensitivity to NK cell-mediated cytotoxicity...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29083930/convolutional-neural-network-for-histopathological-analysis-of-osteosarcoma
#12
Rashika Mishra, Ovidiu Daescu, Patrick Leavey, Dinesh Rakheja, Anita Sengupta
Pathologists often deal with high complexity and sometimes disagreement over osteosarcoma tumor classification due to cellular heterogeneity in the dataset. Segmentation and classification of histology tissue in H&E stained tumor image datasets is a challenging task because of intra-class variations, inter-class similarity, crowded context, and noisy data. In recent years, deep learning approaches have led to encouraging results in breast cancer and prostate cancer analysis. In this article, we propose convolutional neural network (CNN) as a tool to improve efficiency and accuracy of osteosarcoma tumor classification into tumor classes (viable tumor, necrosis) versus nontumor...
October 30, 2017: Journal of Computational Biology: a Journal of Computational Molecular Cell Biology
https://www.readbyqxmd.com/read/29080556/a-new-mutation-independent-approach-to-cancer-therapy-inhibiting-oncogenic-ras-and-myc-by-targeting-mitochondrial-biogenesis
#13
Bela Ozsvari, Federica Sotgia, Michael P Lisanti
Here, we used MCF7 cells as a model system to interrogate how MYC/RAS co-operativity contributes to metabolic flux and stemness in breast cancer cells. We compared the behavior of isogenic MCF7 cell lines transduced with c-Myc or H-Ras (G12V), either individually or in combination. Cancer stem cell (CSC) activity was measured using the mammosphere assay. c-Myc augmented both mammosphere formation and mitochondrial respiration, without any effects on glycolytic flux. In contrast, H-Ras (G12V) synergistically augmented both mammosphere formation and glycolysis, but only in combination with c-Myc, directly demonstrating MYC/RAS co-operativity...
October 27, 2017: Aging
https://www.readbyqxmd.com/read/29075821/mastopexy-on-reconstructed-breast-following-massive-weight-loss-an-innovative-technique-using-dermo-capsular-flaps
#14
A Cogliandro, M Barone, G Cassotta, R Salzillo, P Persichetti
BACKGROUND: We have developed a dermo-capsular flap mastopexy technique for patients who have experienced massive weight loss after breast reconstruction. The aim of this technique is to lift the inframammary fold, adequately cover the implant, and remove excess skin, elevating the breast and obtaining symmetry with the contralateral breast. METHODS: Between January 2014 and February 2017, we performed this technique on 20 women who were candidates for second-stage breast reconstruction following nipple-sparing mastectomy...
October 26, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29075819/augmentation-mastopexy-with-a-dermal-encapsulated-round-or-anatomic-autoprosthesis
#15
Safvet Ors
INTRODUCTION: Several factors, such as aging, pregnancy, and weight loss, reduce the elasticity of the breast tissue, and ptosis occurs. Due to aging and gravity, it is not possible to completely prevent breast ptosis. The goal is to delay the recurrence of ptosis as much as possible. PATIENTS AND METHODS: This study included 20 female patients aged 25-55 years. The patients who underwent surgery had different levels of ptosis. Although the patients wanted their breasts to be lifted and an increase in projection, they did not want implants to be used...
October 26, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29075815/recent-advances-on-the-application-of-negative-pressure-external-volume-expansion-in-breast-plastic-surgery
#16
REVIEW
Wenyue Liu, Jie Luan
BACKGROUND: External volume expansion (EVE) has been effectively applied as an assistance to fat transplantation on breast plastic surgery. Many indicators and refinements have been made in clinical practice; meanwhile, the related mechanism and more optimized preclinical model also have been explored in experimental studies. METHODS: A literature search was conducted using PubMed with the keywords: EVE, negative pressure, breast enlargement, breast augmentation, breast reconstruction, breast plastic surgery and breast aesthetic surgery...
October 26, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29068969/positive-effect-of-incubated-adipose-derived-mesenchymal-stem-cells-on-microfat-graft-survival
#17
Jong Woo Choi, Sung-Chan Kim, Eun-Jung Park, Ju-A Lee, Woo Shik Jeong
Autologous fat grafting is commonly used for soft tissue augmentation, but its unpredictably high resorption rate remains a major limitation. Although adipose-derived mesenchymal stem cells (ASCs) are an attractive candidate for enhancing graft retention, their poor posttransplantation viability limits their application. The authors aimed to evaluate the effect of incubated ASCs on microfat graft survival in an immunocompromised mouse model. Lipoaspirates for microfat injection were collected from the wasted lower abdominal adipose tissues of 5 patients who had undergone breast reconstructive surgery with an abdominal flap...
October 24, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29068922/breast-cleavage-remodeling-with-fat-grafting-a-safe-way-to-optimize-symmetry-and-to-reduce-intermammary-distance
#18
José Maria Serra-Mestre, Randolfo Fernandez Peñuela, Vanessa Foti, Francesco D'Andrea, José Maria Serra-Renom
BACKGROUND: In their descriptions of the ideal breast, most studies have focused primarily on the dimensions, shape, and proportions. The distance between the breasts has only very rarely been considered. The intermammary distance and the medial symmetry between the breasts are important parts of the outcome of surgery and have a strong bearing on patient satisfaction. However, the control surgeons have over these factors is only relative, and depends heavily on the underlying anatomical characteristics of the patients...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29068893/reply-subfascial-primary-breast-augmentation-with-fat-grafting-a-review-of-156-cases
#19
Nathalie Kerfant, Anne-Sophie Henry, Weiguo Hu, Alexandre Marchac, Eric Auclair
No abstract text is available yet for this article.
October 14, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29068887/subfascial-primary-breast-augmentation-with-fat-grafting-a-review-of-156-cases
#20
Javier Vera Cucchairo
No abstract text is available yet for this article.
October 14, 2017: Plastic and Reconstructive Surgery
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