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https://www.readbyqxmd.com/read/28646783/heart-rate-variability-in-patients-with-major-depression-disorder-during-a-clinical-autonomic-test
#1
Xiuwen Chen, Rongqian Yang, Danni Kuang, Lei Zhang, Ruixue Lv, Xiong Huang, Fengchun Wu, Guohui Lao, Shanxing Ou
Major depression disorder (MDD) patients express dysfunction autonomic nervous system (ANS) and reduced heart rate variability (HRV). However, previous researches mainly focused on examining resting state without considering a series of stimulation tests of ANS between MDD patients and healthy people. For this purpose, 40 healthy people and 40 MDD patients participated and finished 10min clinical autonomic test-Ewing test. Parameters of HRV such as time domain, frequency domain, and nonlinear dynamical parameters were calculated...
June 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28642732/autonomic-function-impairment-and-brain-perfusion-deficit-in-parkinson-s-disease
#2
Wei-Che Lin, Pei-Chin Chen, Chih-Cheng Huang, Nai-Wen Tsai, Hsiu-Ling Chen, Hung-Chen Wang, Kun-Hsien Chou, Meng-Hsiang Chen, Yi-Wen Chen, Cheng-Hsien Lu
INTRODUCTION: Autonomic disorders have been recognized as important Parkinson's disease (PD) components. Some vulnerable structures are related to the central autonomic network and have also been linked to autonomic function alterations. The aims of the study are to evaluate the severity of the autonomic dysfunction and the cortical hypoperfusion using arterial spin labeling (ASL) MRI. And then, possible relationships of significant between-group differences in perfusion pattern to clinical variables and autonomic functions were examined to determine the pharmaceutical effects of dopaminergic treatment on cerebral blood flow (CBF) in patients with PD...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28642099/developmental-cardiovascular-physiology-of-the-olive-ridley-sea-turtle-lepidochelys-olivacea
#3
Dane Alan Crossley, Janna Lee Crossley, Camilla Smith, Martha Harfush, Hermilo Sánchez-Sánchez, Mónica Vanessa Garduño-Paz, José Fernando Méndez-Sánchez
Our understanding of reptilian cardiovascular development and regulation has increased substantially for two species the American alligator (Alligator mississippiensis) and the common snapping turtle (Chelydra serpentina) during the past two decades. However, what we know about cardiovascular maturation in many other species remains poorly understood or unknown. Embryonic sea turtles have been studied to understand the maturation of metabolic function, but these studies have not addressed the cardiovascular system...
June 19, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28641963/modulation-of-the-heart-s-electrical-properties-by-the-anticonvulsant-drug-retigabine
#4
Lena Rubi, Michael Kovar, Eva Zebedin-Brandl, Xaver Koenig, Manuel Dominguez-Rodriguez, Hannes Todt, Helmut Kubista, Stefan Boehm, Karlheinz Hilber
Retigabine, currently used as antiepileptic drug, has a wide range of potential medical uses. Administration of the drug in patients can lead to QT interval prolongation in the electrocardiogram and to cardiac arrhythmias in rare cases. This suggests that the drug may perturb the electrical properties of the heart, and the underlying mechanisms were investigated here. Effects of retigabine on currents through human cardiac ion channels, heterologously expressed in tsA-201 cells, were studied in whole-cell patch-clamp experiments...
June 19, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28640758/consecutive-ultra-short-term-heart-rate-variability-to-track-dynamic-changes-in-autonomic-nervous-system-during-and-after-exercise
#5
Xiang Chen, Ruijie Yao, Gezhen Yin, Jin Li
OBJECTIVE: Quantitative measurement of the dynamic changes in autonomic nervous system (ANS) during and after exercise has great significance in clinical, sports training and other fields. A consecutive ultra-short-term (30 s, UST) heart rate variability (HRV) method was proposed to track the exercise-induced autonomic control of heart rate (HR). APPROACH: Twenty-three healthy young men participated in the study. The first four stages of the Modified Bruce Protocol (S0-S3) were performed...
June 22, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28639079/autonomic-nervous-system-response-to-stressors-in-newly-diagnosed-patients-with-multiple-sclerosis
#6
Miroslav Vlcek, Adela Penesova, Richard Imrich, Milada Meskova, Martina Mravcova, Lucia Grunnerova, Alexandra Garafova, Monika Sivakova, Peter Turcani, Branislav Kollar, Daniela Jezova
Autonomic dysfunction is commonly detected in patients with multiple sclerosis (MS). However, data evaluating autonomic nervous system function in early MS are limited. Present study investigates response to two different stressors in newly diagnosed MS patients, looking for the signs of autonomic dysfunction at the beginning of the disease. We examined 19 MS patients and 19 age, sex, and body mass index matched healthy controls. MS patients were newly diagnosed, untreated, and with low expanded disability status scale (EDSS) values [median 1...
June 21, 2017: Cellular and Molecular Neurobiology
https://www.readbyqxmd.com/read/28638839/broken-heart-syndrome-in-a-patient-on-maintenance-hemodialysis
#7
Sukhdeep Bhogal, Vatsal Ladia, Puja Sitwala, Kailash Bajaj, Vijay Ramu, Timir Paul
Context:Broken heart syndrome or Takotsubo cardiomyopathy (TC) is a disorder characterized by transient left ventricular apical ballooning that almost invariably precedes emotional or physical stress. Although the patients with chronic kidney disease on hemodialysis have shown to exhibit sustained activity of sympathetic nervous system, the presentation of TC in these patients is a rare entity with few case reports in the literature. Case Report: A 75-year-old female with past medical history of end-stage renal disease presented with chest pressure and heaviness that started during her maintenance hemodialysis session...
April 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28637815/the-pro-inflammatory-cytokine-tumor-necrosis-factor-alpha-excites-subfornical-organ-neurons
#8
Nick James Simpson, Alastair V Ferguson
Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine implicated in cardiovascular and autonomic regulation via actions in the central nervous system. TNFα(-/-) mice do not develop angiotensin II (ANG II)-induced hypertension, and administration of TNFα into the bloodstream of rats increases blood pressure and sympathetic tone. Recent studies have shown that lesion of the subfornical organ (SFO) attenuates the hypertensive and autonomic effects of TNFα, while direct administration of TNFα into the SFO increases blood pressure, suggesting the SFO to be a key site for the actions of TNFα...
June 21, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28637693/neuroblast-differentiation-during-development-and-in-neuroblastoma-requires-kif1b%C3%AE-mediated-transport-of-trka
#9
Stuart M Fell, Shuijie Li, Karin Wallis, Anna Kock, Olga Surova, Vilma Rraklli, Carolin S Höfig, Wenyu Li, Jens Mittag, Marie Arsenian Henriksson, Rajappa S Kenchappa, Johan Holmberg, Per Kogner, Susanne Schlisio
We recently identified pathogenic KIF1Bβ mutations in sympathetic nervous system malignancies that are defective in developmental apoptosis. Here we deleted KIF1Bβ in the mouse sympathetic nervous system and observed impaired sympathetic nervous function and misexpression of genes required for sympathoadrenal lineage differentiation. We discovered that KIF1Bβ is required for nerve growth factor (NGF)-dependent neuronal differentiation through anterograde transport of the NGF receptor TRKA. Moreover, pathogenic KIF1Bβ mutations identified in neuroblastoma impair TRKA transport...
May 15, 2017: Genes & Development
https://www.readbyqxmd.com/read/28637099/aggregation-and-phosphorylation-of-%C3%AE-synuclein-with-proteinase-k-resistance-in-focal-%C3%AE-synucleinopathy-predominantly-localized-to-the-cardiac-sympathetic-nervous-system
#10
Nei Fukasawa, Takahiro Fukuda, Masato Nagaoka, Tohru Harada, Hiroyuki Takahashi, Masahiro Ikegami
Aggregates of α-synuclein, a major component of Lewy bodies (LBs) and Lewy neurites (LNs), are distributed throughout the nervous system, including the central nervous system (CNS), sympathetic ganglia, enteric nervous system (ENS), cardiac and pelvic plexuses, submandibular gland, adrenal medulla and skin, in incidental Lewy body disease (ILBD), Parkinson's disease (PD), dementia with Lewy bodies (DLB), and pure autonomic failure (PAF) [1-3]. Here we report focal α-synucleinopathy predominantly localized to the cardiac sympathetic nervous system (SNS)...
June 21, 2017: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/28630389/a-case-report-of-the-first-ganglioneuroblastoma-of-the-parotid-gland-of-an-the-adult
#11
Aldo Bove, Rossana Percario, Andrea De Carlo, Barbara Zappacosta
The ganglioneuroblastoma is a rare form of pediatric tumor, involving innerved tissues of the nervous sympathetic system, whose evolution is very hard to foresee. A 38 year-old patient whose histologic exam unexpectedly showed ganglioneuroblastoma, underwent a parotidectomy. Three years after surgery the patient is in optimal clinical conditions, without any radiological signs or clinical relapses. KEY WORDS: Ganglioneuroblastoma, Parotid gland, Parodidectomy.
May 26, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28628383/cardiovascular-response-of-an-acute-exergame-session-in-prepubertal-obese-children
#12
Herikson Araújo Costa, Antonio Carlos Silva-Filho, Carlos José Dias, Vicenilma Andrade Martins, Thiago Mendes, André Rabelo, Francisco Navarro, Emerson Silami-Garcia, Cristiano Mostarda, Mario Sevílio
PURPOSE: We aimed to analyze the acute autonomic response of obese and eutrophic prepubertal boys to an exergame (EXG) session. MATERIALS AND METHOD: Nine eutrophic (8.89 ± 2.71 years of age and 16.42% ± 6.30% body fat) and nine obese boys (8.70 ± 1.16 years of age and 40.76% ± 4.2% body fat) participated. Nutritional state was determined using World Health Organization guidelines. Variables were collected at rest, immediately post (IP), and 60 minutes after a 20 minutes EXG session...
June 2017: Games for Health
https://www.readbyqxmd.com/read/28627793/increased-sympathetic-outflow-induces-adaptation-to-acute-experimental-pain
#13
Lior Dayan, Uri Hochberg, Hadas Nahman-Averbuch, Silviu Brill, Jacob N Ablin, Giris Jacob
BACKGROUND: There are interrelationships between the autonomic nervous system and pain. This study aims to explore the effect of different autonomic manipulations on pain perception and modulation. METHODS: Twenty healthy subjects (10 men and 10 women, mean age 25±3) participate in this single-blinded, semi-randomized, controlled study, which included 2 study visits. Warm and heat pain thresholds, conditioned pain modulation and pain adaptation were tested before and after administration of phenylephrine, clonidine, yohimbine and saline...
June 19, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28627308/hormonal-and-neuromuscular-responses-to-breastfeeding-a-pilot-study
#14
Madalynn Neu, Zhaoxing Pan, Ashley Haight, Karen Fehringer, Katrina Maluf
OBJECTIVES: Difficult breastfeeding in the first weeks after birth may result in muscle tension in infants and activation of the maternal hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS). Our primary objective was to examine the feasibility of collecting neuroendocrine markers of maternal HPA axis and SNS activation (salivary cortisol and α-amylase [sAA]) and electromyographic (EMG) markers of infant distress during feeding in the first 2 weeks after birth...
July 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28620841/device-based-approaches-for-the-treatment-of-arterial-hypertension
#15
REVIEW
Jens Jordan
Device-based antihypertensive treatments have primarily been developed and clinically tested for patients with hypertension refractory to pharmacological treatment. Most but not all device-based treatments target the sympathetic nervous system and provided important new insight in the mechanisms of human hypertension. This review provides an overview on the scientific rational and clinical data on recent device-based antihypertensive treatment approaches. Device-based treatments targeting the sympathetic nervous system include catheter-based renal nerve ablation, electrical carotid sinus stimulation, modulation of baroreflex transduction through a dedicated carotid stent, carotid body denervation, and deep brain stimulation...
July 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28617680/pulse-photoplethysmographic-amplitude-and-heart-rate-variability-during-laparoscopic-cholecystectomy-a-prospective-observational-study
#16
Riccardo Colombo, Ferdinando Raimondi, Alberto Corona, Andrea Marchi, Beatrice Borghi, Simone Pellegrin, Paola Bergomi, Tommaso Fossali, Stefano Guzzetti, Alberto Porta
BACKGROUND: Surgical stress affects the autonomic nervous system by increasing sympathetic outflow. One method of monitoring sympathetic activity is pulse photoplethysmographic analysis. From this two indices can be derived - autonomic nervous system state (ANSS) and ANSS index (ANSSi). It has recently been claimed that these indices can be used to measure sympathetic activity in anaesthetised patients, but their validity has not yet been demonstrated. OBJECTIVE: To measure changes in pulse photoplethysmographic indices and determine any agreement with autonomic nervous system modulation of the cardiovascular system in healthy study participants during surgery under general anaesthesia...
June 15, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28617378/-the-influence-of-growing-seizure-readiness-on-the-autonomic-regulation-of-the-heart
#17
M L Mamalyga, L M Mamalyga
AIM: To study the functional state of the heart in a progressive increase of seizure readiness (SR) due to pentylenetetrazole kindling. MATERIAL AND METHODS: The study was carried out on male rats of the Wistar line. Simultaneous telemetric monitoring of electrocardiogram and electroencephalogram on-line was used. Individual SR of animals in 7- and 27 day pentylenetetrazole kindling was determined. RESULTS: The decrease in the index of LF/HF after 7 days of kindling reflects a compensatory reaction of the autonomic nervous system...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28612516/autonomic-nervous-system-function-in-adolescent-migraineurs
#18
Seiji Yoshida, Hidetaka Tanaka, Midori Mizutani, Ryota Nakao, Naoyuki Okamoto, Mitsugu Kajiura, Yukiko Kanbara, Hiroshi Tamai
BACKGROUND: Migraine is a common and disabling neurological disorder. Studies attempting to determine a relationship between migraine and the autonomic nervous system (ANS) have been inconclusive. Moreover, pediatric studies are extremely limited. Therefore, the present study investigated interictal ANS function in adolescent migraineurs. METHODS: We studied 21 patients with migraine and 26 healthy controls. Beat-to-beat blood pressure (BP) and heart rate (HR) were noninvasively and continuously measured in the supine and standing positions...
June 14, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28611608/coping-style-modifies-general-and-affective-autonomic-reactions-of-domestic-pigs-in-different-behavioral-contexts
#19
Annika Krause, Birger Puppe, Jan Langbein
Based on individual adaptive strategies (coping), animals may react differently to environmental challenges in terms of behavior and physiology according to their emotional perception. Emotional valence as well as arousal may be derived by measuring vagal and sympathetic tone of the autonomic nervous system (ANS). We investigated the situation-dependent autonomic response of 16 domestic pigs with either a reactive or a proactive coping style, previously selected according to the backtest which is accepted in piglets to assess escape behavior...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28607756/heart-rate-variability-is-differentially-altered-in-multiple-sclerosis-implications-for-acute-worsening-and-progressive-disability
#20
Valeria Studer, Camilla Rocchi, Caterina Motta, Benedetta Lauretti, Jacopo Perugini, Laura Brambilla, Lorena Pareja-Gutierrez, Giorgia Camera, Francesca Romana Barbieri, Girolama A Marfia, Diego Centonze, Silvia Rossi
BACKGROUND: Sympathovagal imbalance has been associated with poor prognosis in chronic diseases, but there is conflicting evidence in multiple sclerosis. OBJECTIVES: The objective of this study was to investigate the autonomic nervous system dysfunction correlation with inflammation and progression in multiple sclerosis. METHODS: Heart rate variability was analysed in 120 multiple sclerosis patients and 60 healthy controls during supine rest and head-up tilt test; the normalised units of low frequency and high frequency power were considered to assess sympathetic and vagal components, respectively...
April 2017: Multiple Sclerosis Journal—Experimental, Translational and Clinical
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