keyword
https://read.qxmd.com/read/38498596/concurrent-validity-of-dynamic-bedside-quantitative-sensory-testing-paradigms-in-breast-cancer-survivors-with-persistent-pain
#21
JOURNAL ARTICLE
Vincent Haenen, Mira Meeus, Nele Devoogdt, Bart Morlion, Lore Dams, Amber De Groote, Anthe Foubert, An De Groef
BACKGROUND: Studies on the concurrent validity of clinically applicable testing protocols for conditioned pain modulation (CPM) and temporal summation of pain (TSP) in breast cancer survivors (BCS) with persistent pain are lacking. OBJECTIVES: This study investigated the concurrent validity of two bedside protocols for CPM and TSP in comparison to a respective reference protocol. The participants' preferences for bedside CPM and TSP protocols were assessed. METHODS: Thirty BCS experiencing persistent pain were included in this study...
January 1, 2024: Scandinavian Journal of Pain
https://read.qxmd.com/read/38498321/online-exercise-programs-for-chronic-nonspecific-neck-pain-a-randomized-controlled-trial-reveals-comparable-effects-of-global-local-and-combined-approaches
#22
JOURNAL ARTICLE
Jente Bontinck, Mira Meeus, Lennard Voogt, Marjolein Chys, Iris Coppieters, Barbara Cagnie, Kayleigh De Meulemeester
OBJECTIVE: Specific neck exercises are recommended in the rehabilitation of chronic nonspecific neck pain. They are unfortunately often accompanied by acute pain flare-ups. Global exercises might be a beneficial addition, as they activate endogenous analgesia without overloading painful structures. However, it is still unclear which type of exercise is most effective. This randomized controlled trial was done to evaluate the effect of an online blended program of global and specific neck exercises, compared to programs including only 1 of both types of exercise...
March 18, 2024: Physical Therapy
https://read.qxmd.com/read/38493609/predictive-models-for-sensory-score-and-physicochemical-composition-of-yuezhou-longjing-tea-using-near-infrared-spectroscopy-and-data-fusion
#23
JOURNAL ARTICLE
Yong Chen, Mengqi Guo, Kai Chen, Xinfeng Jiang, Zezhong Ding, Haowen Zhang, Min Lu, Dandan Qi, Chunwang Dong
In this study, NIR quantitative prediction model was established for sensory score and physicochemical components of different varieties and quality grades of Yuezhou Longjing tea. Firstly, L, a, b color factors and diffuse reflection spectral data are collected for each sample. Subsequently, the original spectrum is preprocessed. Three techniques for selecting variables, CARS, BOSS, and SPA, were utilized to extract optimal feature bands. Finally, the spectral data extracted from feature bands were fused with L, a and b color factors to build SVR and PLSR prediction models...
March 14, 2024: Talanta
https://read.qxmd.com/read/38492631/quantitative-sensory-testing-in-canine-musculoskeletal-pain-findings-from-a-systematic-review-meta-analysis-feasibility-assessment-and-limitations
#24
JOURNAL ARTICLE
B P Monteiro, C Otis, R Nitulescu, E Troncy
Quantitative sensory testing (QST) allows the study of pain mechanisms, patient phenotyping, and response to therapy. The goals of this study were to conduct a systematic review of the use of QST in dogs with musculoskeletal disease including osteoarthritis (OA), and to assess, by means of a meta-analysis, the ability of QST to differentiate affected dogs from healthy controls. The study protocol was registered; three bibliographic databases were screened. Studies involving QST in healthy dogs and those with musculoskeletal disease were included...
March 14, 2024: Veterinary Journal
https://read.qxmd.com/read/38492568/sound-elicits-stereotyped-facial-movements-that-provide-a-sensitive-index-of-hearing-abilities-in-mice
#25
JOURNAL ARTICLE
Kameron K Clayton, Kamryn S Stecyk, Anna A Guo, Anna R Chambers, Ke Chen, Kenneth E Hancock, Daniel B Polley
Sound elicits rapid movements of muscles in the face, ears, and eyes that protect the body from injury and trigger brain-wide internal state changes. Here, we performed quantitative facial videography from mice resting atop a piezoelectric force plate and observed that broadband sounds elicited rapid and stereotyped facial twitches. Facial motion energy (FME) adjacent to the whisker array was 30 dB more sensitive than the acoustic startle reflex and offered greater inter-trial and inter-animal reliability than sound-evoked pupil dilations or movement of other facial and body regions...
March 6, 2024: Current Biology: CB
https://read.qxmd.com/read/38492300/effects-of-post-fermentation-addition-of-green-tea-extract-for-sulfur-dioxide-replacement-on-sauvignon-blanc-wine-phenolic-composition-antioxidant-capacity-colour-and-mouthfeel-attributes
#26
JOURNAL ARTICLE
Yi Yang, Zhijing Ye, Yunxuan Qin, Sreeni Pathirana, Leandro Dias Araujo, Neill J Culley, Paul A Kilmartin
This study examines the feasibility of replacing SO2 in a New Zealand Sauvignon Blanc wine with a green tea extract. The treatments included the control with no preservatives (C), the addition of green tea extract at 0.1 and 0.2 g/L (T1 and T2), and an SO2 treatment at 50 mg/L (T3). Five monomeric phenolic compounds were detected in the green tea extract used for the experiment, and their concentrations ranged in the order (-)-epigallocatechin gallate > (-)-epigallocatechin > (-)-epicatechin > (-)-epicatechin gallate > gallic acid...
March 11, 2024: Food Chemistry
https://read.qxmd.com/read/38486872/beyond-numbers-integrating-qualitative-analysis-into-quantitative-sensory-testing-for-neuropathic-pain
#27
JOURNAL ARTICLE
Martine Bordeleau, Matthieu Vincenot, Miroslav Bačkonja, Yenisel Cruz-Almeida, Julia Forstenpointner, Lynn Gauthier, Serge Marchand, Catherine Mercier, Don Daniel Ocay, Michel PrudHomme, Hélène Ruel, Jan Vollert, Guillaume Léonard
This article investigates the benefits of adopting qualitative and quantitative sensory testing (QQST) in sensory assessment, with a focus on understanding neuropathic pain. The innovative QQST method combines participant qualitative experiences with quantitative psychophysical measurements, offering a more varied interpretation of sensory abnormalities and normal sensory function. This article also explores the steps for the optimization of the method by identifying qualitative signs of sensory abnormalities and standardizing data collection...
2024: Front Pain Res (Lausanne)
https://read.qxmd.com/read/38485630/neurofeedback-and-epilepsy-renaissance-of-an-old-self-regulation-method
#28
REVIEW
A Marchi, R Guex, M Denis, N El Youssef, F Pizzo, C-G Bénar, F Bartolomei
Neurofeedback is a brain-computer interface tool enabling the user to self-regulate their neuronal activity, and ultimately, induce long-term brain plasticity, making it an interesting instrument to cure brain disorders. Although this method has been used successfully in the past as an adjunctive therapy in drug-resistant epilepsy, this approach remains under-explored and deserves more rigorous scientific inquiry. In this review, we present early neurofeedback protocols employed in epilepsy and provide a critical overview of the main clinical studies...
March 13, 2024: Revue Neurologique
https://read.qxmd.com/read/38483556/complex-alterations-in-inflammatory-pain-and-analgesic-sensitivity-in-young-and-ageing-female-rats-involvement-of-asic3-and-nav1-8-in-primary-sensory-neurons
#29
JOURNAL ARTICLE
Diego N Messina, Emanuel D Peralta, Cristian G Acosta
OBJECTIVE AND DESIGN: Our aim was to determine an age-dependent role of Nav1.8 and ASIC3 in dorsal root ganglion (DRG) neurons in a rat pre-clinical model of long-term inflammatory pain. METHODS: We compared 6 and 24 months-old female Wistar rats after cutaneous inflammation. We used behavioral pain assessments over time, qPCR, quantitative immunohistochemistry, selective pharmacological manipulation, ELISA and in vitro treatment with cytokines. RESULTS: Older rats exhibited delayed recovery from mechanical allodynia and earlier onset of spontaneous pain than younger rats after inflammation...
March 14, 2024: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://read.qxmd.com/read/38483469/testing-biological-and-psychological-pathways-of-emotion-regulation-as-a-primary-mechanism-of-action-in-yoga-interventions-for-chronic-low-back-pain-protocol-for-a-randomized-controlled-trial
#30
JOURNAL ARTICLE
Angela R Starkweather, Wanli Xu, Katherine E Gnall, Mariel Emrich, Camille L Garnsey, Zachary E Magin, Weizi Wu, Joseph Fetta, Erik J Groessl, Crystal Park
BACKGROUND: Interventions that promote adaptive emotion regulation (ER) skills reduce pain in patients with chronic pain; however, whether the effects of yoga practice on chronic low back pain (CLBP) are due to improvements in ER remains to be examined. OBJECTIVE: This study will test whether the effects of yoga on CLBP (improved pain severity and interference) are mediated by improved ER, the extent to which effects are related to specific aspects of ER, and the role of pain sensitization as a mediator or moderator of effects...
March 14, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38482371/small-fibre-integrity-and-axonal-pathology-in-the-rat-model-of-experimental-autoimmune-neuritis
#31
JOURNAL ARTICLE
Pia Renk, Melissa Sgodzai, Rafael Klimas, Alina Blusch, Thomas Grüter, Jeremias Motte, Xiomara Pedreiturria, Jeannette Gebel, Philipp Gobrecht, Dietmar Fischer, Ralf Gold, Kalliopi Pitarokoili
Experimental autoimmune neuritis is a common animal model for acute human immune-mediated polyneuropathies. Although already established in 1955, a number of pathophysiological mechanisms remain unknown. In this study, we extensively characterize experimental autoimmune neuritis progression in Lewis rats, including new insights into the integrity of small nerve fibres, neuropathic pain and macrophage activation. Acute experimental autoimmune neuritis was induced with P253-78 peptide and consequently investigated using the gait analysis system CatWalk XT, electrophysiological and histopathological analyses, quantitative polymerase chain reaction (PCR), dorsal root ganglia outgrowth studies, as well as the von Frey hair and Hargreaves tests...
2024: Brain communications
https://read.qxmd.com/read/38479843/reproducible-spinal-cord-quantitative-mri-analysis-with-the-spinal-cord-toolbox
#32
JOURNAL ARTICLE
Jan Valošek, Julien Cohen-Adad
The spinal cord plays a pivotal role in the central nervous system, providing communication between the brain and the body and containing critical motor and sensory networks. Recent advancements in spinal cord MRI data acquisition and image analysis have shown a potential to improve the diagnostics, prognosis, and management of a variety of pathological conditions. In this review, we first discuss the significance of standardized spinal cord MRI acquisition protocol in multi-center and multi-manufacturer studies...
March 12, 2024: Magnetic Resonance in Medical Sciences: MRMS
https://read.qxmd.com/read/38479809/parallel-streams-of-direct-corticogeniculate-feedback-from-mid-level-extrastriate-cortex-in-the-macaque-monkey
#33
JOURNAL ARTICLE
Matthew Adusei, Edward M Callaway, W Martin Usrey, Farran Briggs
First order thalamic nuclei receive feedforward signals from peripheral receptors and relay these signals to primary sensory cortex. Primary sensory cortex, in turn, provides reciprocal feedback to first order thalamus. Because the vast majority of sensory thalamocortical inputs target primary sensory cortex, their complementary corticothalamic neurons are assumed to be similarly restricted to primary sensory cortex. We upend this assumption by characterizing morphologically diverse neurons in multiple mid-level visual cortical areas of the primate ( Macaca mulatta ) brain that provide direct feedback to the primary visual thalamus, the dorsal lateral geniculate nucleus (LGN)...
March 13, 2024: ENeuro
https://read.qxmd.com/read/38477065/longitudinal-analysis-of-serum-neurofilament-light-chain-levels-as-marker-for-neuronal-damage-in-hereditary-transthyretin-amyloidosis
#34
JOURNAL ARTICLE
Milou Berends, Anne F Brunger, Johan Bijzet, Bart-Jan Kroesen, Gea Drost, Fiete Lange, Charlotte E Teunissen, Sjors In 't Veld, Alexander Fje Vrancken, Reinold O B Gans, Bouke P C Hazenberg, Paul A van der Zwaag, Hans L A Nienhuis
OBJECTIVE: To evaluate serum neurofilament light chain (sNfL) as biomarker of disease onset, progression and treatment effect in hereditary transthyretin (ATTRv) amyloidosis patients and TTR variant ( TTR v) carriers. METHODS: sNfL levels were assessed longitudinally in persistently asymptomatic TTR v carriers ( N  = 12), persistently asymptomatic ATTRv amyloidosis patients (defined as asymptomatic patients but with amyloid detectable in subcutaneous abdominal fat tissue) ( N  = 8), in TTR v carriers who developed polyneuropathy ( N  = 7) and in ATTRv amyloidosis patients with polyneuropathy on treatment (TTR-stabiliser ( N  = 20) or TTR-silencer ( N  = 18))...
March 13, 2024: Amyloid: the International Journal of Experimental and Clinical Investigation
https://read.qxmd.com/read/38476081/factors-related-to-preoperative-anxiety-in-older-patients-with-sensory-impairment-a-cross-sectional-study
#35
JOURNAL ARTICLE
Kayeon Mo, Kisook Kim
AIM: To identify the factors related to preoperative anxiety in older adults with sensory impairment. DESIGN: Descriptive quantitative research design. METHODS: Study participants were 120 older adults admitted to a tertiary hospital in Seoul, South Korea to undergo eye or ear surgery. Data were collected from 11 February to 30 April 2023. The collected data were analysed using descriptive statistics, t-tests, ANOVA, and multiple regression analysis using SPSS 28...
March 13, 2024: Journal of Clinical Nursing
https://read.qxmd.com/read/38472852/characterization-of-the-effects-of-low-sodium-salt-substitution-on-sensory-quality-protein-oxidation-and-hydrolysis-of-air-dried-chicken-meat-and-its-molecular-mechanisms-based-on-tandem-mass-tagging-labeled-quantitative-proteomics
#36
JOURNAL ARTICLE
Jianhao Li, Zihang Shi, Xiankang Fan, Lihui Du, Qiang Xia, Changyu Zhou, Yangying Sun, Baocai Xu, Daodong Pan
The effects of low-sodium salt mixture substitution on the sensory quality, protein oxidation, and hydrolysis of air-dried chicken and its molecular mechanisms were investigated based on tandem mass tagging (TMT) quantitative proteomics. The composite salt formulated with 1.6% KCl, 0.8% MgCl2 , and 5.6% NaCl was found to improve the freshness and texture quality scores. Low-sodium salt mixture substitution significantly decreased the carbonyl content (1.52 nmol/mg), surface hydrophobicity (102.58 μg), and dimeric tyrosine content (2...
February 28, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38472793/comparison-of-aroma-compounds-and-sensory-characteristics-between-two-different-types-of-rice-based-baijiu
#37
JOURNAL ARTICLE
Fan Wu, Shaohui Fan, Guoliang He, Siyu Liang, Yan Xu, Ke Tang
Rice-based Baijiu has gained popularity in the Chinese market. Qingya-flavored Baijiu, a variant of Xiaoqu-fermented Baijiu, employs rice as its primary raw material, with an improved production process compared to traditional rice-flavored Baijiu. We comprehensively characterized and compared the aroma profiles of these two rice-based Baijiu types using static sensory experiments (QDA, quantitative descriptive analysis) and dynamic sensory experiments (TDS, temporal dominance of sensations). Qingya-flavored Baijiu exhibited pronounced plant, oily, and roasted aromas, while traditional rice-flavored Baijiu displayed more prominent fruity, floral, and sour notes...
February 23, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38471409/effects-of-high-frequency-strengthening-on-pain-sensitivity-and-function-in-female-runners-with-chronic-patellofemoral-pain
#38
JOURNAL ARTICLE
Brian J Eckenrode, David M Kietrys, Allison Brown, J Scott Parrott, Brian Noehren
OBJECTIVE: To investigate the effects of a high frequency strengthening program on function, pain, and pain sensitization in female runners with chronic patellofemoral pain (PFP). DESIGN: Cross-sectional study. SETTING: University laboratory. PARTICIPANTS: Thirty female runners (mean age 32 ± 8.1 years) with chronic PFP completed an 8-week home strengthening program. MAIN OUTCOME MEASURES: Variables assessed at baseline, 8-weeks, and 12 weeks included single leg step down test (SLSD), pain, Anterior Knee Pain Scale (AKPS), University of Wisconsin Running Injury and Recovery Index (UWRI), and quantitative sensory testing...
March 5, 2024: Physical Therapy in Sport
https://read.qxmd.com/read/38469882/elevated-liver-enzymes-and-fasting-glucose-levels-correlate-with-neuropathy-in-patients-diagnosed-with-alcohol-use-disorder-independently-of-the-blood-thiamine-levels
#39
JOURNAL ARTICLE
Michail Papantoniou, Thomas Zampelis, Panagiotis Kokotis, Elias Tzavellas, Thomas Paparrigopoulos, Stylianos Chatzipanagiotou, Chrysoula Nikolaou, Michail Rentzos
AIMS: Chronic alcohol consumption is well known to cause peripheral neuropathy, affecting both small and large nerve fibers. The aim of this study was to correlate biochemical and neurophysiological findings and investigate possible biomarkers and risk factors for pathogenetic mechanisms of neuropathy in patients diagnosed with alcohol use disorder (AUD). METHODS: Ninety patients diagnosed with AUD were enrolled in this prospective study over a period of 3 years...
January 17, 2024: Alcohol and Alcoholism
https://read.qxmd.com/read/38462137/the-role-of-attention-in-immersion-the-two-competitor-model
#40
JOURNAL ARTICLE
Daniel J Strauss, Alexander L Francis, Jonas Vibell, Farah I Corona-Strauss
Currently, we face an exponentially increasing interest in immersion, espe- cially sensory-driven immersion, mainly due to the rapid development of ideas and business models centered around a digital virtual universe as well as the increasing availability of affordable immersive technologies for education, com- munication, and entertainment. However, a clear definition of 'immersion', in terms of established neurocognitive concepts and measurable properties, remains elusive, slowing research on the human side of immersive interfaces...
March 8, 2024: Brain Research Bulletin
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