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Quantitative sensorial

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https://www.readbyqxmd.com/read/28340251/thermal-qst-phenotypes-associated-with-response-to-lumbar-epidural-steroid-injections-a-pilot-study
#1
Dermot P Maher, Weihua Ding, Sarabdeep Singh, Arissa Opalacz, Claire Fishman, Mary Houghton, Shihab Ahmed, Lucy Chen, Jianren Mao, Yi Zhang
Objective.:  Response to lumbar epidural steroid injection in lumbar radicular pain varies. The purpose of this study is to characterize the changes in quantitative sensory testing (QST) phenotypes of subjects and compare the QST characteristics in patients who do respond to treatment of radicular pain with a lumbar epidural steroid injection (ESI). Design.:  Prospective, observational pilot study. Setting.:  Outpatient pain center. Methods...
March 13, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28335745/ipsilateral-and-contralateral-sensory-changes-in-healthy-subjects-after-experimentally-induced-concomitant-sensitization-and-hypoesthesia
#2
Elena K Enax-Krumova, Stephanie Pohl, Andrea Westermann, Christoph Maier
BACKGROUND: In unilateral neuropathic pain. e.g. after peripheral nerve injury, both positive and negative sensory signs occur often, accompanied by minor but equally directed contralateral sensory changes. To mimic this feature, we experimentally aimed to induce concomitant c-fibre sensitization and block in healthy subjects and analyzed the bilateral sensory changes by quantitative sensory testing (QST) using the protocol of the German Research Network on Neuropathic Pain. METHODS: Twenty eight healthy subjects were firstly randomized in 2 groups to receive either topical capsaicin (0...
March 23, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28333580/air-quality-measurements-from-rubber-bands-to-tapping-the-rainbow
#3
George M Hidy, Peter K Mueller, Samuel L Altshuler, Judith C Chow, John G Watson
It is axiomatic that good measurements are integral to good public policy for environmental protection. The generalized term for "measurements" includes sampling and quantitation, data integrity, documentation, network design, sponsorship and operations, and archiving and accessing for applications. Each of these components has evolved and advanced over the last 200 years as knowledge of atmospheric chemistry and physics has matured. Air quality was first detected by what people could see smoke and smell contaminated air...
March 23, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28330489/profiling-intraoral-neuropathic-disturbances-following-lingual-nerve-injury-and-in-burning-mouth-syndrome
#4
Amely Hartmann, Robin Seeberger, Malte Bittner, Roman Rolke, Claudia Welte-Jzyk, Monika Daubländer
BACKGROUND: The aim of the study was to analyse intraoral neurophysiological changes in patients with unilateral lingual nerve lesions as well as patients with Burning Mouth Syndrome (BMS) by applying a standardized Quantitative Sensory Testing (QST) protocol. METHODS: The study included patients suffering from a peripheral lesion of the lingual nerve (n = 4), from BMS (n = 5) and healthy controls (n = 8). Neurophysiological tests were performed in the innervation areas of the tongue bilaterally...
March 23, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28328653/somatosensory-functions-in-survivors-of-critical-illness
#5
Philipp Baumbach, Theresa Götz, Albrecht Günther, Thomas Weiss, Winfried Meissner
OBJECTIVES: There is growing evidence for increased levels of pain and reduced health-related quality of life in survivors of critical illness. Recent studies showed marked small nerve fiber pathology in critically ill patients, which may contribute to chronic pain states and reduced physical recovery after ICU discharge. Primary objective of this study was the comparison of somatosensory functions between survivors of critical illness 6 months after ICU discharge and controls. In post hoc analyses, we aimed to identify associations between small fiber deficits, pain, health-related quality of life, and clinical data...
March 21, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28328646/sensory-characterization-of-odors-in-used-disposable-absorbent-incontinence-products
#6
Heléne Widén, Susanne Alenljung, Ulla Forsgren-Brusk, Gunnar Hall
PURPOSE: The objectives of this study were to characterize the odors of used incontinence products by descriptive analysis and to define attributes to be used in the analysis. A further objective was to investigate to what extent the odor profiles of used incontinence products differed from each other and, if possible, to group these profiles into classes. SUBJECTS AND SETTING: Used incontinence products were collected from 14 residents with urinary incontinence living in geriatric nursing homes in the Gothenburg area, Sweden...
March 21, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28328632/use-of-processed-nerve-allografts-to-repair-nerve-injuries-greater-than-25-mm-in-the-hand
#7
Brian Rinker, Jozef Zoldos, Renata V Weber, Jason Ko, Wesley Thayer, Jeffrey Greenberg, Fraser J Leversedge, Bauback Safa, Gregory Buncke
Processed nerve allografts (PNAs) have been demonstrated to have improved clinical results compared with hollow conduits for reconstruction of digital nerve gaps less than 25 mm; however, the use of PNAs for longer gaps warrants further clinical investigation. Long nerve gaps have been traditionally hard to study because of low incidence. The advent of the RANGER registry, a large, institutional review board-approved, active database for PNA (Avance Nerve Graft; AxoGen, Inc, Alachua, FL) has allowed evaluation of lower incidence subsets...
March 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28328574/the-long-term-reliability-of-static-and-dynamic-quantitative-sensory-testing-in-healthy-individuals
#8
Anna Marcuzzi, Paul J Wrigley, Catherine M Dean, Roger Adams, Julia M Hush
Quantitative sensory tests (QST) have been increasingly used to investigate alterations in somatosensory function in a wide range of painful conditions. The interpretation of these findings is based on the assumption that the measures are stable and reproducible. To date, reliability of QST has been investigated for short test-retest intervals. The aim of this study was to investigate the long-term reliability of a multimodal QST assessment in healthy people, with testing conducted on three occasions over 4-months...
March 21, 2017: Pain
https://www.readbyqxmd.com/read/28324985/a-novel-thermal-tactile-stimulator-device-for-quantitative-sensory-testing
#9
Umit Kursun, Olcay Kursun, Oleg V Favorov
This paper outlines the design and preliminary experimental results of a novel thermal stimulator device designed to measure, from some perspectives, brain health. The device delivers some thermal stimuli and asks the subject about his perception about them, thus checking the correctness of the perception and even the existence of certain perceptual illusions that would normally be present in healthy cortex and nervous system. This noninvasive sensory technology is cheap and easy to use, it has the potential to be used in telemonitoring systems and in empowering the individual to track his/her progression over time on the provided neuropathy tests...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323720/neuroprognostication-after-cardiac-arrest-in-the-light-of-targeted-temperature-management
#10
Mauro Oddo, Hans Friberg
PURPOSE OF REVIEW: Delayed awakening after targeted temperature management (TTM) and sedation is frequent among cardiac arrest patients. Differentiating between prolonged coma and irreversible cerebral damage can be challenging, therefore the utilization of a multimodal approach is recommended by international guidelines. Here, we discuss indications and advantages/disadvantages of available modalities for coma prognostication and describe new tools to improve our accuracy for outcome prediction...
March 20, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/28322188/a-molecular-mechanism-for-the-topographic-alignment-of-convergent-neural-maps
#11
Elise Savier, Stephen J Eglen, Amélie Bathélémy, Martine Perraut, Frank W Pfrieger, Greg Lemke, Michael Reber
Sensory processing requires proper alignment of neural maps throughout the brain. In the superficial layers of the superior colliculus of the midbrain, converging projections from retinal ganglion cells and neurons in visual cortex must be aligned to form a visuotopic map, but the basic mechanisms mediating this alignment remain elusive. In a new mouse model, ectopic expression of ephrin-A3 (Efna3) in a subset of retinal ganglion cells, quantitatively altering the retinal EFNAs gradient, disrupts cortico-collicular map alignment onto the retino-collicular map, creating a visuotopic mismatch...
March 14, 2017: ELife
https://www.readbyqxmd.com/read/28302148/thermal-quantitative-sensory-testing-in-healthy-dutch-children-and-adolescents-standardized-test-paradigm-and-dutch-reference-values
#12
Gerbrich E van den Bosch, Monique van Dijk, Dick Tibboel, Abraham J Valkenburg
BACKGROUND: Quantitative sensory testing (QST) is often used to measure children's and adults' detection- and pain thresholds in a quantitative manner. In children especially the Thermal Sensory Analyzer (TSA-II) is often applied to determine thermal detection and pain thresholds. As comparisons between studies are hampered by the different testing protocols used, we aimed to present a standard protocol and reference values for thermal detection- and pain thresholds in children. METHODS: Our standard testing protocol includes reaction time dependent and independent tests and takes about 14-18 min to complete...
March 16, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28296936/spatial-analysis-improves-the-detection-of-early-corneal-nerve-fiber-loss-in-patients-with-recently-diagnosed-type-2-diabetes
#13
Dan Ziegler, Karsten Winter, Alexander Strom, Andrey Zhivov, Stephan Allgeier, Nikolaos Papanas, Iris Ziegler, Jutta Brüggemann, Bernd Ringel, Sabine Peschel, Bernd Köhler, Oliver Stachs, Rudolf F Guthoff, Michael Roden
Corneal confocal microscopy (CCM) has revealed reduced corneal nerve fiber (CNF) length and density (CNFL, CNFD) in patients with diabetes, but the spatial pattern of CNF loss has not been studied. We aimed to determine whether spatial analysis of the distribution of corneal nerve branching points (CNBPs) may contribute to improving the detection of early CNF loss. We hypothesized that early CNF decline follows a clustered rather than random distribution pattern of CNBPs. CCM, nerve conduction studies (NCS), and quantitative sensory testing (QST) were performed in a cross-sectional study including 86 patients recently diagnosed with type 2 diabetes and 47 control subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28290294/behavior-of-yeast-inoculated-during-semi-dry-coffee-fermentation-and-the-effect-on-chemical-and-sensorial-properties-of-the-final-beverage
#14
Luciana Silva Ribeiro, Maria Gabriela da Cruz Pedrozo Miguel, Suzana Reis Evangelista, Pamela Mynsen Machado Martins, Joshua van Mullem, Maisa Honorio Belizario, Rosane Freitas Schwan
Pulped Mundo Novo and Ouro Amarelo coffee beans were inoculated with Saccharomyces cerevisiae (CCMA 0200 and CCMA 0543) during semi-dry coffee fermentation and compared with a non-inoculated control. Samples were collected throughout the fermentation process (12days) to evaluate the persistence of the inoculum by Real-Time quantitative PCR (qPCR). Also, the chemical composition of the beans was determined by HPLC and GC-MS and the roasted beans were sensorial evaluated using the cupping test. S. cerevisiae CCMA 0543 had an average population of 5...
February 2017: Food Research International
https://www.readbyqxmd.com/read/28290286/modelling-the-cooking-doneness-via-integrating-sensory-evaluation-and-kinetics
#15
Jingpeng Li, Li Deng, Zhengyu Jin, Yong Yan
The aim of the current work was to develop a novel method to model and quantitatively determine cooking doneness via integrating sensory evaluation and kinetics based on the maturity value (M value) which was redefined. The well-done food was first selected from a series of samples with different M values by sensory evaluation, the average termination maturity values (AMT values) were obtained in accordance with the weighted M values of the selected doneness samples. Among, the changes of M values were assumed to be accorded with the first-order reaction kinetic model and a specific zM value was set as well...
February 2017: Food Research International
https://www.readbyqxmd.com/read/28289462/the-perception-of-low-salt-bread-among-preschool-children-and-the-role-of-educational-personnel-in-creating-a-positive-attitude-towards-reformulated-food
#16
Boris Kovac, Maja Knific
INTRODUCTION: The purpose of this study was to identify the possibility of unnoticed reduction in salt content of bread as a basic food in the diet of preschool children. The response of children to less salty bread and the role of teachers and teacher assistants in the introduction of novelties into children's nutrition ware studied. METHODS: Using hedonic sensory evaluation in the case of bread, the perception of salty taste and responses of preschool children to salt reduction were observed...
March 1, 2017: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/28287532/dynamic-quantitative-sensory-testing-to-characterize-central-pain-processing
#17
Ian G Mackey, Eric A Dixon, Kevin Johnson, Jiang-Ti Kong
Central facilitation and modulation of incoming nociceptive signals play an important role in the perception of pain. Disruption in central pain processing is present in many chronic pain conditions and can influence responses to specific therapies. Thus, the ability to precisely describe the state of central pain processing has profound clinical significance in both prognosis and prediction. Because it is not practical to record neuronal firings directly in the human spinal cord, surrogate behavior tests become an important tool to assess the state of central pain processing...
February 16, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28285516/investigation-on-key-molecules-of-hlb-induced-orange-juice-off-flavor
#18
Johannes Kiefl, Birgit Kohlenberg, Anja Hartmann, Katja Obst, Susanne Paetz, Gerhard E Krammer, Stephan Trautzsch
Orange fruits from Huanglongbing (HLB) infected trees do not fully mature and show a severe off-flavor described as bitter-harsh, metallic and less juicy and fruity. The investigation of juice from HLB infected (HLBOJ) and healthy control oranges (COJ) by gas chromatography mass spectrometry showed higher concentrations of fruity esters such as ethyl butyrate and ethyl 2-methylbutyrate, and soapy-waxy alkanals such as octanal and decanal in the COJ whereas the HLBOJ showed higher concentrations of green aldehydes like hexanal and degradation compounds of limonene and linalool like α-terpineol...
March 11, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28284801/functional-connectivity-and-activity-of-white-matter-in-somatosensory-pathways-under-tactile-stimulations
#19
Xi Wu, Zhipeng Yang, Stephen K Bailey, Jiliu Zhou, Laurie E Cutting, John C Gore, Zhaohua Ding
Functional MRI has proven to be effective in detecting neural activity in brain cortices on the basis of blood oxygenation level dependent (BOLD) contrast, but has relatively poor sensitivity for detecting neural activity in white matter. To demonstrate that BOLD signals in white matter are detectable and contain information on neural activity, we stimulated the somatosensory system and examined distributions of BOLD signals in related white matter pathways. The temporal correlation profiles and frequency contents of BOLD signals were compared between stimulation and resting conditions, and between relevant white matter fibers and background regions, as well as between left and right side stimulations...
March 8, 2017: NeuroImage
https://www.readbyqxmd.com/read/28284736/contributions-of-sensory-tuning-to-auditory-vocal-interactions-in-marmoset-auditory-cortex
#20
Steven J Eliades, Xiaoqin Wang
During speech, humans continuously listen to their own vocal output to ensure accurate communication. Such self-monitoring is thought to require the integration of information about the feedback of vocal acoustics with internal motor control signals. The neural mechanism of this auditory-vocal interaction remains largely unknown at the cellular level. Previous studies in naturally vocalizing marmosets have demonstrated diverse neural activities in auditory cortex during vocalization, dominated by a vocalization-induced suppression of neural firing...
March 8, 2017: Hearing Research
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