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Drug eluting balloon

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https://www.readbyqxmd.com/read/29792404/culotte-stenting-for-coronary-bifurcation-lesions-with-2nd-and-3rd-generation-everolimus-eluting-stents-the-celtic-bifurcation-study
#1
Simon J Walsh, Colm G Hanratty, Stuart Watkins, Keith G Oldroyd, Niall T Mulvihill, Mark Hensey, Alex Chase, Dave Smith, Nick Cruden, James C Spratt, Darren Mylotte, Tom Johnson, Jonathan Hill, Hafiz M Hussein, Kris Bogaerts, Marie-Claude Morice, David P Foley
AIMS: The aim of this study was to provide contemporary outcome data for patients with de novo coronary disease and Medina 1,1,1 lesions who were treated with a culotte two-stent technique, and to compare the performance of two modern-generation drug-eluting stent (DES) platforms, the 3-connector XIENCE and the 2-connector SYNERGY. METHODS AND RESULTS: Patients with Medina 1,1,1 bifurcation lesions who had disease that was amenable to culotte stenting were randomised 1:1 to treatment with XIENCE or SYNERGY DES...
May 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29786412/the-use-of-scoring-balloons-in-the-superficial-femoral-artery
#2
Simon Bays
Percutaneous transluminal angioplasty and stenting is becoming increasingly the first line treatment for patients with both claudication and critical limb ischaemia instead of surgery, with the aim of returning the patient's quality of life in the former and preventing amputation. Drug eluting technologies have seen a large surge in popularity in recent years, and significant patient benefits have been seen with the use of drug eluting stents and balloons over the use of plain balloon angioplasty. Unfortunately in many patients with arterial disease there is significant vessel wall calcification - this can theoretically be a barrier to drug delivery, and can also be a contributing factor to flow limiting dissection and the subsequent need for bail out stenting...
May 22, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29785307/a-review-of-percutaneous-transluminal-angioplasty-in-hemodialysis-fistula
#3
REVIEW
Ioannis Bountouris, Georgia Kritikou, Nikolaos Degermetzoglou, Konstantinos Ioannis Avgerinos
The number of patients in dialysis increases every year. In this review, we will evaluate the role of percutaneous transluminal angioplasty (PTA) according to patency of arteriovenous fistula and grafts. The main indication of PΤΑ is stenosis > 50% or obstruction of the vascular lumen of an arteriovenous fistula and graft. It is usually performed under local anesthesia. The infection rate is as low as the number of complications. Fistula can be used in dialysis in the same day without the need for a central venous catheter...
2018: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/29764968/how-to-prevent-and-manage-radiation-induced-coronary-artery-disease
#4
REVIEW
Jason R Cuomo, Sean P Javaheri, Gyanendra K Sharma, Deepak Kapoor, Adam E Berman, Neal L Weintraub
Radiation-induced coronary heart disease (RICHD) is the second most common cause of morbidity and mortality in patients treated with radiotherapy for breast cancer, Hodgkin's lymphoma and other prevalent mediastinal malignancies. The risk of RICHD increases with radiation dose. Exposed patients may present decades after treatment with manifestations ranging from asymptomatic myocardial perfusion defects to ostial, triple-vessel disease and sudden cardiac death. RICHD is insidious, with a long latency and a tendency to remain silent late into the disease course...
May 15, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29754850/biologic-drug-effect-and-particulate-embolization-of-drug-eluting-stents-versus-drug-coated-balloons-in-healthy-swine-femoropopliteal-arteries
#5
Sho Torii, Kazuyuki Yahagi, Hiroyoshi Mori, Emanuel Harari, Maria E Romero, Frank D Kolodgie, Brandt Young, Anthony Ragheb, Renu Virmani, Aloke V Finn
PURPOSE: To compare the drug effect in treated vessels and downstream effects in distal skeletal muscle of drug-coated balloons (DCBs) and drug-eluting stents (DESs) in a healthy preclinical swine model. MATERIALS AND METHODS: Four groups of treated iliofemoral arteries (percutaneous transluminal angioplasty [PTA]+DES, DCB+DES, DCB+bare metal stent [BMS], and DCB alone) of 12 healthy swine were assessed, with euthanasia at 30 days. Biological drug effect was evaluated using smooth muscle cell (SMC) loss score according to both depth and circumference as well a neointimal fibrin and medial proteoglycan scores which were compared between the 4 groups...
May 10, 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29748151/patient-specific-3d-printing-simulation-to-guide-complex-coronary-intervention
#6
Manuel Oliveira-Santos, Eduardo Oliveira Santos, Ana Vera Marinho, Luís Leite, Jorge Guardado, Vítor Matos, Guilherme Mariano Pego, João Silva Marques
The field of three-dimensional printing applied to patient-specific simulation is evolving as a tool to enhance intervention results. We report the first case of a fully simulated percutaneous coronary intervention in a three-dimensional patient-specific model to guide treatment. An 85-year-old female presented with symptomatic in-stent restenosis in the ostial circumflex and was scheduled for percutaneous coronary intervention. Considering the complexity of the anatomy, patient setting and intervention technique, we elected to replicate the coronary anatomy using a three-dimensional model...
May 7, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29747322/-safety-and-efficacy-of-rotational-atherectomy-in-the-interventional-treatment-of-coronary-chronic-total-occlusion-lesions
#7
J Y Ma, J J Guo, L Hou, F Zhang, K Yao, D Huang, H Lu, Y X Dai, C G Li, S F Chang, Q Qin, L Ge, J Y Qian, J B Ge
Objective: To investigate the safety and efficacy of rotational atherectomy in the interventional treatment of coronary chronic total occlusion lesions. Methods: In this retrospective study,a total of 31 consecutive patients with coronary chronic total occlusion(CTO) lesions underwent rotational atherectomy in our hospital from February 2004 to December 2016 were enrolled,and the clinical features were analyzed. Coronary atherectomy was performed if balloon failed to cross the CTO lesions or balloon could not be fully dilated in the CTO lesions after wire crossing...
April 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29737639/current-management-of-in-stent-restenosis
#8
REVIEW
Ae Young Her, Eun Seok Shin
Despite the advent of the drug-eluting stents (DES) and improved stent design, in-stent restenosis (ISR) remains a challenging problem. The currently available options for treatment of ISR include angioplasty alone, repeat stenting with DES or drug-coated balloons. Several recent studies have compared the available options for treating ISR in an attempt to identify the preferred therapeutic strategy. In this review, we will discuss the currently available therapeutic strategies for the management of patients with ISR and the evidence supporting their use...
May 2018: Korean Circulation Journal
https://www.readbyqxmd.com/read/29731024/the-potential-effects-of-new-stent-platforms-for-coronary-revascularization-in-patients-with-diabetes
#9
REVIEW
Gustavo S Guandalini, Sripal Bangalore
Coronary artery disease in patients with diabetes mellitus (DM) is characterized by extensive atherosclerosis, longer lesions, and diffuse distal disease. Consequently, these patients have worse outcomes after coronary revascularization, regardless of the modality used. Traditionally, coronary artery bypass grafting (CABG) has been regarded as more effective than percutaneous coronary intervention (PCI) in patients with DM, likely because of more complete revascularization and protection against disease progression in the bypass segment...
May 2018: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29730377/adventitial-drug-delivery-of-dexamethasone-to-improve-primary-patency-in-the-treatment-of-superficial-femoral-and-popliteal-artery-disease-12-month-results-from-the-dance-clinical-trial
#10
Mahmood K Razavi, Dennis Donohoe, Ralph B D'Agostino, Michael R Jaff, George Adams
OBJECTIVES: This study was designed to evaluate outcomes of adventitial dexamethasone delivery adjunctive to standard endovascular revascularization in femoropopliteal peripheral artery disease. BACKGROUND: Drug-coated balloons and drug-eluting stents improve patency of endovascular interventions with passive diffusion of antiproliferative drugs. Adventitial dexamethasone delivery targets the initial triggers of the inflammatory reaction to injury, thus potentially providing a potent antirestenotic strategy...
April 27, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29730237/drug-coated-balloon-in-peripheral-artery-disease
#11
REVIEW
Madhan Shanmugasundaram, Sangeetha Murugapandian, Huu Tam Truong, Kapildeo Lotun, Subhash Banerjee
Peripheral artery disease (PAD) is highly prevalent but is often underdiagnosed and undertreated. Lower extremity PAD can often be life style limiting. Revascularization in carefully selected lower extremity PAD patients improves symptoms and functional status. Surgical revascularization used to be the only available strategy, but in the recent years, endovascular strategies have gained popularity due to faster recovery times with low morbidity and mortality rates. Endovascular procedures have increased significantly in the United States in the past few years...
April 21, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29726622/improved-stent-expansion-with-prolonged-compared-with-short-balloon-inflation-a-meta-analysis
#12
Marwan Saad, Mahesh Bavineni, Barry F Uretsky, Srikanth Vallurupalli
BACKGROUND: Despite evidence from individual studies suggesting that prolonged inflation improves coronary stent expansion, relatively shorter inflation times are commonly employed in clinical practice. METHODS: We performed an electronic search of PubMed, Web of Science, Cochrane, and CINAHL databases to retrieve outcome studies comparing prolonged versus short inflation times during stent deployment. Outcomes studied included minimal stent diameter (MSD) and minimal stent area (MSA)...
May 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29715170/treatment-of-diffuse-right-coronary-aneurysmal-disease-with-standard-drug-eluting-stent-scaffolding-of-polytetrafluoroethylene-covered-stents
#13
Jeffrey Rossi, Terence Hill, Jaikirshan Khatri
Demonstration of a novel technique to safely exclude long aneurysmal segments that require multiple covered stents in a single segment. In addition, these images and video series demonstrate the usefulness of balloon-assisted GuideLiner tracking to pass bulky equipment to the distal segments of heavily diseased vessels.
May 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29705386/gender-is-not-a-predictor-of-mortality-or-major-adverse-cardiovascular-events-in-patients-undergoing-percutaneous-coronary-intervention-for-acute-coronary-syndromes
#14
Angeline Josiah, Ahmad Farshid
BACKGROUND: Historically, studies of percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) have reported worse outcomes for women. We sought to determine if contemporary PCI techniques eliminate gender differences in PCI outcomes. METHODS: This was a retrospective study of 4776 consecutive patients who underwent PCI for acute coronary syndromes between January 2008 and July 2015. Primary outcomes studied were major adverse cardiovascular events (MACE) and death at 1year...
April 4, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29691767/prognostic-impact-of-final-kissing-balloon-technique-after-crossover-stenting-for-the-left-main-coronary-artery-from-the-aoi-lmca-registry
#15
Koji Nishida, Mamoru Toyofuku, Takeshi Morimoto, Masanobu Ohya, Yasushi Fuku, Hirooki Higami, Kyohei Yamaji, Hiromi Muranishi, Yuhei Yamaji, Daisuke Furukawa, Tomohisa Tada, Euihong Ko, Kazushige Kadota, Kenji Ando, Hiroki Sakamoto, Takashi Tamura, Kazuya Kawai, Takeshi Kimura
It is still uncertain whether the final kissing balloon technique (FKBT) is mandatory after crossover stenting for the left main coronary artery (LMCA). Assessing Optimal Percutaneous Coronary Intervention for LMCA (AOI-LMCA) registry, a 6-center retrospective registry, enrolled 1809 consecutive patients for LMCA stenting in Japan. In the present analysis, 5-year clinical outcomes were compared between non-FKBT (n = 160) and FKBT (n = 578) groups in patients treated with crossover stenting with drug-eluting stents from the LMCA to the left anterior descending artery...
April 24, 2018: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/29687699/merging-the-properties-of-a-sirolimus-coated-balloon-with-those-of-a-bioresorbable-polymer-sirolimus-eluting-stent-to-address-the-diabetes-issue-results-from-the-en-abl-multicenter-registry
#16
Luca Testa, Sameer Dani, Devang Desai, Rashmit Pandya, Pritesh Parekh, Nirav Bhalani, Arvind Sharma, Chirag Seth, Manish Doshi, Prakash Sojitra, Poonam Chodvadiya, Gopee Dutta, Francesco Bedogni
BACKGROUND: Patients with diabetes mellitus (DM) have poorer outcomes after percutaneous coronary intervention than patients without diabetes. The Abluminus DES+TM drug-eluting stent (DES) features a novel technology of fusion coating of PLLA bioresorbable polymer on both the abluminal surface of the stent and exposed parts of the balloon. AIM: To evaluate the efficacy/safety profile of the Abluminus DES+ in an all-comers population with minimal exclusion criteria and with a specific focus on diabetic patients...
April 20, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29685691/mid-term-clinical-outcomes-after-bailout-drug-eluting-stenting-for-suboptimal-drug-coated-balloon-results-insights-from-a-milan-registry
#17
Satoru Mitomo, Richard J Jabbour, Antonio Mangieri, Marco Ancona, Damiano Regazzoli, Akihito Tanaka, Francesco Giannini, Mauro Carlino, Matteo Montorfano, Alaide Chieffo, Azeem Latib, Antonio Colombo
BACKGROUND: Drug-coated balloon (DCB) is an alternative to drug-eluting stent (DES) for the treatment of small vessel or in-stent restenosis (ISR) lesions, with bailout stenting reserved for poor results after DCB inflation (residual stenosis or dissection). Data regarding bailout stenting with DES are limited. The aim of this study was to evaluate clinical outcomes after bailout stenting with DES for suboptimal DCB results. METHODS: From June 2009 to December 2015, patients who underwent bailout DES implantation for suboptimal results after DCB (residual stenosis > 30% or type C-F dissection) in 2 high-volume centers in Italy were analyzed...
April 13, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29682422/comparison-of-clinical-outcomes-after-drug-eluting-balloon-and-drug-eluting-stent-use-for-in-stent-restenosis-related-acute-myocardial-infarction-a-retrospective-study
#18
Chih-Yuan Fang, Hsiu-Yu Fang, Chien-Jen Chen, Cheng-Hsu Yang, Chiung-Jen Wu, Wei-Chieh Lee
Background: Good results of drug-eluting balloon (DEB) use are achieved in in-stent restenosis (ISR) lesions, small vessel disease, long lesions, and bifurcations. However, few reports exist about DEB use in acute myocardial infarction (AMI) with ISR. This study's aim was to evaluate the efficacy of DEB for AMI with ISR. Methods: Between November 2011 and December 2015, 117 consecutive patients experienced AMI including ST-segment elevation MI, and non-ST-segment elevation MI due to ISR, and received percutaneous coronary intervention (PCI)...
2018: PeerJ
https://www.readbyqxmd.com/read/29671104/long-term-follow-up-in-patients-treated-by-stent-implantation-for-post-ablation-pulmonary-vein-stenosis
#19
Elisabeth Iversen, Erik J S Packer, Synne M Sandberg, Øyvind Bleie, Per Ivar Hoff, Peter Schuster
PURPOSE: Symptomatic severe pulmonary vein stenosis (PVS) after catheter ablation of atrial fibrillation (AF) is a rare but well-recognized complication. Treatment options include pulmonary vein angioplasty with or without drug eluting balloons or angioplasty with stent implantation. The treatment of choice is unclear. In our center, pulmonary vein stenting is the treatment of choice for significantly stenotic veins. We present the long-term clinical outcome of 9 patients treated with stent implantation...
April 18, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29667231/feasibility-and-clinical-outcomes-of-rotational-atherectomy-for-heavily-calcified-side-branches-of-complex-coronary-bifurcation-lesions-in-the-real-world-practice-of-the-drug-eluting-stent-era
#20
Yu-Wei Chen, Chieh-Shou Su, Wei-Chun Chang, Tsun-Jui Liu, Kae-Woei Liang, Chih-Hung Lai, Hong-Xu Liu, Wen-Lieng Lee
OBJECTIVES: To evaluate the outcomes of rotational atherectomy for heavily-calcified side branches of coronary bifurcation lesions. BACKGROUND: Side-branch (SB) preservation is clinically important but technically challenging in heavily-calcified non-left main true bifurcation lesions. SB rotational atherectomy (SB RA) is sometimes mandatory but the clinical outcomes are not well studied. METHODS: We retrospectively studied the outcomes of patients who underwent RA at our institute for heavily calcified, balloon-uncrossable or-undilatable SB lesions over an approximately 5-year period (January 2011 to September 2016)...
April 17, 2018: Journal of Interventional Cardiology
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