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https://www.readbyqxmd.com/read/28938532/modulation-of-gdf11-expression-and-synaptic-plasticity-by-age-and-training
#1
Emanuela De Domenico, Giovanna D'Arcangelo, Isabella Faraoni, Mattia Palmieri, Virginia Tancredi, Grazia Graziani, Paola Grimaldi, Lucio Tentori
The Growth Differentiation Factor 11 (GDF11) has been controversially involved in the aging/rejuvenation process. To clarify whether GDF11 is differently expressed during aging, we have evaluated GDF11 levels in skeletal muscles and hippocampi of young and old mice, sedentary or subjected to a 12-weeks triweekly training protocol. The results of real-time PCR and Western blot analyses indicate that skeletal muscles of sedentary old mice express higher levels of GDF11 compared to young animals (p < 0.05)...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28938473/the-role-of-episodic-postprandial-peptides-in-exercise-induced-compensatory-eating
#2
Catherine Gibbons, John E Blundell, Phillipa Caudwell, Dominic-Luc Webb, Per M Hellström, Erik Näslund, Graham Finlayson
Purpose: Prolonged physical activity gives rise to variable degrees of body weight and fat loss, and is associated with variability in appetite control (hunger and energy intake). Whether these effects are modulated by postprandial 'episodic' peptides is unclear. We examined the role of postprandial peptide response in compensatory eating during 12-weeks aerobic exercise and in response to high (HFLC) and low fat (LFHC) meals. Methods: 32 overweight/obese individuals - 16 completed 12-weeks aerobic exercise and 16 were age- and BMI-matched non-exercising controls...
August 18, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28938249/absence-of-fitness-improvement-is-associated-with-outcomes-in-heart-failure-patients
#3
Esmée A Bakker, Johan A Snoek, Esther P Meindersma, Maria T E Hopman, Louise Bellersen, André L M Verbeek, Dick H J Thijssen, Thijs M H Eijsvogels
PURPOSE: To examine the clinical impact of cardiorespiratory fitness (CRF) and improvements in CRF after cardiac rehabilitation (CR) in heart failure (HF) patients for their risk of all-cause mortality and unplanned hospitalization. Secondly, to investigate possible factors associated with the absence of improvement in CRF after rehabilitation. METHODS: We included 155 HF patients receiving CR between October 2009 and January 2015. Patients performed an incremental bicycle test to assess CRF through peak oxygen uptake (VO2-peak) before and after CR-based supervised exercise training...
September 21, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28938098/an-integrative-review-on-conflict-management-styles-among-nursing-students-implications-for-nurse-education
#4
REVIEW
Leodoro J Labrague, Denise M McEnroe-Petitte
OBJECTIVES: Nurse education plays a critical role in the achievement of conflict management skills in nursing students. However, a wider perspective on this concept has not been explored. This paper is a report of a review appraising and synthesizing existing empirical studies describing conflict management styles among nursing students. DESIGN: An integrative review method guided this review. DATA SOURCES: Five (5) bibliographic databases (CINAHL, Medline, Psych Info, Embase and SCOPUS) were searched to locate relevant articles...
September 15, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28937931/design-and-development-of-a-mobile-exercise-application-for-home-care-aides-and-older-adult-medicaid-home-and-community-based-clients
#5
Margaret Danilovich, Laura Diaz, Gustavo Saberbein, William Healey, Gail Huber, Daniel Corcos
We describe a community-engaged approach with Medicaid Home and Community-Based Services (HCBS) home care aide (HCA), client, and physical therapist stakeholders to develop a mobile application (app) exercise intervention through focus groups and interviews. Participants desired a short exercise program with modification capabilities, goal setting, and mechanisms to track progress. Concerns regarding participation were training needs and feasibility within usual care services. Technological preferences were for simple, easy-to-use, and engaging content...
September 22, 2017: Home Health Care Services Quarterly
https://www.readbyqxmd.com/read/28937309/metabolic-and-hormonal-responses-to-different-resistance-training-systems-in-elderly-men
#6
Marcos R Paunksnis, Alexandre L Evangelista, Cauê V La Scala Teixeira, Gustavo Alegretti João, Rafael M Pitta, Angelica C Alonso, Aylton Figueira, Andrey Jorge Serra, Julien S Baker, Brad Jon Schoenfeld, Danilo S Bocalini
OBJECTIVE: To compare acute and sub-acute responses in hormonal profile and metabolic parameters in elderly people who participated in two methods of strength training (ST) with equalized loads. METHODS AND MATERIALS: A total of 12 elder individuals (65 ± 3 years) were randomly assigned to two training methods: constant intensity (CI, 3 sets of 10 repetitions with 75% of 1RM) and variable intensity (VI, 1st set: 12 repetitions at 67% of 1RM > 2nd set: 10 repetitions at 75% of 1RM and 3rd set: 8 repetitions at 80% of 1RM)...
September 22, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28937244/cardiac-at1-receptor-dependent-and-igf1-receptor-independent-signaling-is-activated-by-a-single-bout-of-resistance-exercise
#7
S Fs Melo, V G Barauna, T Fernandes, E C Carmo, C Ro Carvalho, E M Oliveira
AT1 receptor (AT1R) blockade prevents physiological cardiac hypertrophy induced by resistance training. Also, our group showed that a single bout of resistance exercise (RE) activates the AKT/mTOR which was also inhibited by AT1R blocker. Here, we investigated whether IGF1-receptor (IGF1-R) and MAPKs were also activated after a single bout of RE. Wistar rats were divided into Sedentary (SED); Sedentary treated with losartan (SED+LOS); Exercise (EX); and Exercise treated with losartan (EX+LOS). Cardiac tissue was obtained 5 and 30 minutes after 4 sets of 12 repetitions of squat exercise (80%1RM)...
September 22, 2017: Physiological Research
https://www.readbyqxmd.com/read/28936936/-treatment-of-dementia
#8
K Blom, G A H van den Elsen, H L Koek, J B Sanders, H C Kruithof, J A H R Claassen
- Treatment options for patients with dementia are limited. This article provides an overview of possible interventions, both pharmaceutical and non-pharmaceutical, for Alzheimer's disease, vascular dementia and mixed dementia.- Pharmaceutical treatment options include cholinesterase inhibitors, memantine and experimental medication. Cholinesterase inhibitors are only recommended for Alzheimer's disease and mixed dementia, not for vascular dementia or mild cognitive impairment. There is no proof of effectiveness for the other pharmaceutical options...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28936887/interpretation-of-correlations-in-clinical-research
#9
Man Hung, Jerry Bounsanga, Maren Wright Voss
BACKGROUND: Critically analyzing research is a key skill in evidence-based practice and requires knowledge of research methods, results interpretation, and applications, all of which rely on a foundation based in statistics. Evidence-based practice makes high demands on trained medical professionals to interpret an ever-expanding array of research evidence. OBJECTIVE: As clinical training emphasizes medical care rather than statistics, it is useful to review the basics of statistical methods and what they mean for interpreting clinical studies...
September 22, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28936703/cross-education-of-muscular-strength-following-unilateral-resistance-training-a-meta-analysis
#10
A Manca, D Dragone, Z Dvir, Franca Deriu
PURPOSE: Cross-education (CE) of strength is a well-known phenomenon whereby exercise of one limb can induce strength gains in the contralateral untrained limb. The only available meta-analyses on CE, which date back to a decade ago, estimated a modest 7.8% increase in contralateral strength following unilateral training. However, in recent years new evidences have outlined larger contralateral gains, which deserve to be systematically evaluated. Therefore, the aim of this meta-analysis was to appraise current data on CE and determine its overall magnitude of effect...
September 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28936625/the-reproducibility-of-4-km-time-trial-tt-performance-following-individualised-sodium-bicarbonate-supplementation-a-randomised-controlled-trial-in-trained-cyclists
#11
Lewis Anthony Gough, Sanjoy Kumar Deb, Andy Sparks, Lars Robert McNaughton
BACKGROUND: Individual time to peak blood bicarbonate (HCO3(-)) has demonstrated good to excellent reproducibility following ingestion of both 0.2 g kg(-1) body mass (BM) and 0.3 g kg(-1) BM sodium bicarbonate (NaHCO3), but the consistency of the time trial (TT) performance response using such an individualised NaHCO3 ingestion strategy remains unknown. This study therefore evaluated the reproducibility of 4-km TT performance following NaHCO3 ingestion individualised to time to peak blood bicarbonate...
September 21, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28935828/daily-resistance-type-exercise-stimulates-overall-muscle-protein-synthesis-rates-in-vivo-in-young-males
#12
Andrew M Holwerda, Kevin J M Paulussen, Maarten Overkamp, Joey S J Smeets, Annemie P Gijsen, Joy P B Goessens, Lex B Verdijk, Luc J C van Loon
BACKGROUND: Resistance-type exercise increases muscle protein synthesis rates during acute post-exercise recovery. The impact of resistance-type exercise training on (local) muscle protein synthesis rates under free living conditions on a day-to-day basis remains unclear. OBJECTIVE: To determine the impact of daily unilateral resistance-type exercise on local myofibrillar protein synthesis rates during a three-day period. METHODS: Twelve healthy young males (22±1 y) were recruited to participate in this study where they performed daily, unilateral resistance-type exercise during a three-day intervention period...
September 21, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28935825/effect-of-tapering-after-a-period-of-high-volume-sprint-interval-training-on-running-performance-and-muscular-adaptations-in-moderately-trained-runners
#13
Casper Skovgaard, Nicki Winfield Almquist, Thue Kvorning, Peter Møller Christensen, Jens Bangsbo
The effect of tapering following a period of high-volume sprint interval training (SIT) and a basic volume of aerobic training on performance and muscle adaptations in moderately trained runners was examined. Eleven (8 males, 3 females) runners (maximum oxygen uptake (VO2-max): 56.8±2.9 mL·min(-1)·kg(-1); mean±SD) conducted high-volume SIT (HV; 20 SIT sessions; 8-12 x 30-s all-out) for 40 days followed by 18 days of tapering (TAP; 4 SIT sessions; 4 x 30-s all-out). Before and after HV as well as midway through and at the end of TAP, the subjects completed a 10-km running test and a repeated running test at 90% of vVO2-max to exhaustion (RRT)...
September 21, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28935628/effect-of-exercise-induced-lactate-elevation-on-brain-lactate-levels-during-hypoglycemia-in-patients-with-type-1-diabetes-and-impaired-awareness-of-hypoglycemia
#14
Evita C Wiegers, Hanne M Rooijackers, Cees J Tack, Hans J M M Groenewoud, Arend Heerschap, Bastiaan E de Galan, Marinette van der Graaf
Since altered brain lactate handling has been implicated in the development of impaired awareness of hypoglycemia (IAH) in type 1 diabetes, the capacity to transport lactate into the brain during hypoglycemia may be relevant in its pathogenesis. High-intensity interval training (HIIT) increases plasma lactate levels. We compared the effect of HIIT-induced hyperlacticacidemia on brain lactate during hypoglycemia between 1) patients with type 1 diabetes and IAH, 2) patients with type 1 diabetes and normal awareness of hypoglycemia (NAH), and 3) healthy non-diabetic participants (n=6 per group)...
September 21, 2017: Diabetes
https://www.readbyqxmd.com/read/28935516/internet-delivered-physiotherapist-prescribed-exercise-and-pain-coping-skills-training-is-beneficial-for-people-with-chronic-knee-pain-commentary
#15
Håvard Østerås, Lennart Bentsen
No abstract text is available yet for this article.
September 18, 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/28935227/physiotherapy-education-and-training-prior-to-upper-abdominal-surgery-is-memorable-and-has-high-treatment-fidelity-a-nested-mixed-methods-randomised-controlled-study
#16
Ianthe Boden, Doa El-Ansary, Nadia Zalucki, Iain K Robertson, Laura Browning, Elizabeth H Skinner, Linda Denehy
OBJECTIVES: To (1) assess memorability and treatment fidelity of pre-operative physiotherapy education prior to elective upper abdominal surgery and, (2) to explore patient opinions on pre-operative education. DESIGN: Mixed-methods analysis of a convenience sample within a larger parallel-group, double-blinded, randomised controlled trial with concealed allocation and intention-to-treat analysis. SETTING: Tertiary Australian hospital. PARTICIPANTS: Twenty-nine patients having upper abdominal surgery attending pre-admission clinic within six-weeks of surgery...
September 1, 2017: Physiotherapy
https://www.readbyqxmd.com/read/28935128/quality-of-life-and-sleep-quality-are-similarly-improved-after-aquatic-or-dry-land-aerobic-training-in-patients-with-type-2-diabetes-a-randomized-clinical-trial
#17
Rodrigo S Delevatti, Felipe Barreto Schuch, Ana Carolina Kanitz, Cristine L Alberton, Elisa Corrêa Marson, Salime Chedid Lisboa, Carolina Dertzbocher Feil Pinho, Luciana Peruchena Bregagnol, Maríndia Teixeira Becker, Luiz Fernando M Kruel
OBJECTIVES: To compare the effects of two aerobic training models in water and on dry-land on quality of life, depressive symptoms and sleep quality in patients with type 2 diabetes. DESIGN: Randomized clinical trial. METHODS: Thirty-five patients with type 2 diabetes were randomly assigned to aquatic aerobic training group (n=17) or dry-land aerobic training group (n=18). Exercise training length was of 12 weeks, performed in three weekly sessions (45min/session), with intensity progressing from 85% to 100% of heart rate of anaerobic threshold during interventions...
September 6, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28934966/effectiveness-of-an-interactive-telerehabilitation-system-with-home-based-exercise-training-in-patients-after-total-hip-or-knee-replacement-study-protocol-for-a-multicenter-superiority-no-blinded-randomized-controlled-trial
#18
Sarah Eichler, Sophie Rabe, Annett Salzwedel, Steffen Müller, Josefine Stoll, Nina Tilgner, Michael John, Karl Wegscheider, Frank Mayer, Heinz Völler
BACKGROUND: Total hip or knee replacement is one of the most frequently performed surgical procedures. Physical rehabilitation following total hip or knee replacement is an essential part of the therapy to improve functional outcomes and quality of life. After discharge from inpatient rehabilitation, a subsequent postoperative exercise therapy is needed to maintain functional mobility. Telerehabilitation may be a potential innovative treatment approach. We aim to investigate the superiority of an interactive telerehabilitation intervention for patients after total hip or knee replacement, in comparison to usual care, regarding physical performance, functional mobility, quality of life and pain...
September 21, 2017: Trials
https://www.readbyqxmd.com/read/28934945/aqua-walking-as-an-alternative-exercise-modality-during-cardiac-rehabilitation-for-coronary-artery-disease-in-older-patients-with-lower-extremity-osteoarthritis
#19
Jong-Young Lee, Kee-Chan Joo, Peter H Brubaker
BACKGROUND: The purpose of this study was to examine the effects of aqua walking (AW) on coronary artery disease (CAD) and cardiorespiratory fitness in older adults with osteoarthritis in the lower extremity and compare it with that of traditional over-ground walking. METHODS: Sixty consecutive eligible patients who had undergone percutaneous coronary intervention for CAD with limited ambulation due to lower extremity osteoarthritis were recruited. They were randomly assigned to the AW program group, treadmill/track walking (TW) program group, or non-exercise control group (CON)...
September 21, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28934191/effects-of-aerobic-exercise-on-brain-metabolism-and-grey-matter-volume-in-older-adults-results-of-the-randomised-controlled-smart-trial
#20
S Matura, J Fleckenstein, R Deichmann, T Engeroff, E Füzéki, E Hattingen, R Hellweg, B Lienerth, U Pilatus, S Schwarz, V A Tesky, L Vogt, W Banzer, J Pantel
There is mounting evidence that aerobic exercise has a positive effect on cognitive functions in older adults. To date, little is known about the neurometabolic and molecular mechanisms underlying this positive effect. The present study used magnetic resonance spectroscopy and quantitative MRI to systematically explore the effects of physical activity on human brain metabolism and grey matter (GM) volume in healthy aging. This is a randomised controlled assessor-blinded two-armed trial (n=53) to explore exercise-induced neuroprotective and metabolic effects on the brain in cognitively healthy older adults...
July 18, 2017: Translational Psychiatry
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