Xi Wang, Li Ma, Sheng Jiang, Junping Wen, Zhaoli Yan, Long Tian, Shan Deng, Boxian Huang, Ilia Stambler, Calogero Caruso, Kyung-Jin Min, Huanxing Su, Kunlin Jin, Jiangfeng Mao, Xueyan Wu, Qin Han, Robert Chunhua Zhao
Aging-related hypogonadism involves complex mechanisms in humans, predominantly relating to the decline of multiple hormones and senile gonads. Late-onset hypogonadism (LOH) and erectile dysfunction (ED) are the main manifestations in men, while premature ovarian insufficiency (POI) and menopause are the main forms in women. Anti-aging measures include lifestyle modification and resistance training, hormonal supplementation, stem cell therapy, metformin, and rapamycin. In this expert consensus, the mechanisms, efficacy, and side effects of stem cell therapy on aging gonadal function are reviewed...
May 9, 2024: Aging and Disease