keyword
https://read.qxmd.com/read/38537140/first-report-of-soybean-root-rot-caused-by-fusarium-proliferatum-in-the-republic-of-korea
#1
JOURNAL ARTICLE
In-Jeong Kang, Mirang Lee, Sang Yun Han, Yul-Ho Kim, Sungwoo Lee
Fusarium species are widespread soilborne pathogens that can cause damping-off, root rot, and wilting in soybean [ Glycine max (L.) Merrill], subsequently leading to significant yield suppression. Several Fusarium spp. have already been documented for their pathogenicity on soybean plants in the Republic of Korea. The nationwide monitoring of soybean diseases continues to identify new pathogenic Fusarium spp. In 2016, five plant samples at R3-R4 growth stages, showing symptoms of wilting in the upper parts and root rot, were collected in Suwon, Gyeonggi, Republic of Korea...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38533429/harmonising-iv-oxycodone-with-paediatric-perioperative-medications-a-compatibility-study-through-y-type-connectors
#2
JOURNAL ARTICLE
Souha H Youssef, Alka Garg, Yunmei Song, Nicole E Wylie, Sanjay Garg
PURPOSE: Co-administering multiple intravenous (IV) agents via Y-connectors is a common practice in hospitalised and fasting surgical patients. However, there is a lack of reliable data confirming the physical compatibility of some combinations including IV oxycodone, a drug that is gaining increasing popularity in the perioperative period. Concern regarding physical drug incompatibilities precludes concurrent coadministration with other common drugs through a single lumen. This can result in the cessation of infusions to allow the administration of other medications, resulting in exacerbation of acute pain...
2024: Drug Design, Development and Therapy
https://read.qxmd.com/read/38531816/simultaneous-determination-of-ibrutinib-dihydroxydiol-ibrutinib-and-zanubrutinib-in-human-plasma-by-liquid-chromatography-mass-spectrometry-mass-spectrometry
#3
JOURNAL ARTICLE
Yu-Jiao Guo, Tian-Tian Du, Yan-Ling Yang, Yang Zhao, Xiang-Long Chen, Hong Ma, Lu-Ning Sun, Yong-Qing Wang
BACKGROUND: Ibrutinib and zanubrutinib are Bruton tyrosine kinase inhibitors used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. Dihydroxydiol ibrutinib (DHI) is an active metabolite of the drug. A liquid chromatography-tandem mass spectrometry method was developed to detect ibrutinib, DHI, and zanubrutinib in human plasma. METHODS: The method involved a protein precipitation step, followed by chromatographic separation using a gradient of 10 mM ammonium acetate (containing 0...
March 21, 2024: Therapeutic Drug Monitoring
https://read.qxmd.com/read/38526778/donkey-like-kirkovirus-is-associated-with-diarrhea-in-piglets
#4
JOURNAL ARTICLE
Panpan Tong, Zunbao Wang, Yueyi Dang, Lei Zhang, Guangwei Song, Xiaozhen Song, Juanjuan Pan, Ling Kuang, Junhui Li, Gang Lu, Jinxin Xie
Kirkovirus (kirV), a seemingly novel virus family, has been found in horses and donkeys. The study's objectives are to investigate the presence of the virus in swine. In this study, donkey-like kirV was detected in rectal swabs of piglets with diarrhea, and the positive rate was found to be 100% (149/149). However, this virus was detected in only one of 261 clinically healthy piglets, which suggested a strong relationship between the kirV and the diarrheic disease. We obtained the whole-genome sequences of three kirVs (Cj-D5, Cj-D32, and Cj-D43), with a length of 3750 nucleotides (nt) and sharing 99...
March 25, 2024: Virus Genes
https://read.qxmd.com/read/38525397/the-effect-of-dextrose-hypotonic-vs-saline-hydration-on-methotrexate-induced-nephrotoxicity-in-male-and-female-rats
#5
JOURNAL ARTICLE
Zahra Hasanpour, Samira Choopani, Farzaneh Ashrafi, Ardeshir Talebi, Mehdi Nematbaksh
BACKGROUND: High-dose methotrexate (HDMTX) as a cytotoxic agent might cause various side effects. Hyperhydration has been implemented as the major strategy to decrease the potential risk of toxicities induced by HDMTX. This study aims to assess the renoprotective effect of hydration with dextrose water (DW) 5% versus normal saline (N/S) 0.9% against methotrexate (MTX) induced nephrotoxicity. MATERIALS AND METHODS: This experimental animal study has been conducted on 36 Wistar rats (200-250 g) categorized into six groups, including male ( n = 6) and female ( n = 6) rats receiving sodium chloride 0...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525147/grain-yield-and-interspecific-competition-in-an-oat-common-vetch-intercropping-system-at-varying-sowing-density
#6
JOURNAL ARTICLE
Ying Wang, Xue Han, Xingyao Zhao, Yanli Zhang, Bingjie Qi, Lijun Li
INTRODUCTION: Oat ( Avena nuda L.) and common vetch ( Vicia sativa L.) intercropping in the northern regions of China has resulted in substantial production capabilities. However, there is currently a dearth of comprehensive research on whether this intercropping system can enhance productivity through increased sowing densities and underlying interspecies interaction mechanisms. METHODS: A two-year field experiment was conducted in 2022 and 2023 to investigate the yield, biological efficiency, economic efficiency, and competition indicators of oats and common vetch in a high-density intercropping system...
2024: Frontiers in Plant Science
https://read.qxmd.com/read/38525021/visible-light-driven-mentha-spicata-l-mediated-ag-doped-bi-2-zr-2-o-7-nanocomposite-for-enhanced-degradation-of-organic-pollutants-electrochemical-sensing-and-antibacterial-applications
#7
JOURNAL ARTICLE
Kurlla Pompapathi, Kurupalya Shivram Anantharaju, Periyakaruppan Karuppasamy, Meena Subramaniam, Bogegowda Uma, Surendra Boppanahalli Siddegowda, Arpita Paul Chowdhury, H C Ananda Murthy
Novel visible-light-driven Ag ( X )-doped Bi2 Zr2 O7 (BZO) nanocomposites in pudina (P) extract ( Mentha spicata L.), X -1, 3, 5, 7, and 9 mol %, were synthesized by the one-pot greener solution combustion method. The as-synthesized nanocomposite materials were characterized by using various spectral [X-ray diffraction (XRD), Fourier transform infrared, UV-visible, UV- diffuse reflectance spectra, X-ray photoelectron spectroscopy], electrochemical (cyclic voltammetry, electrochemical impedance spectroscopy), and analytical (scanning electron microscopy-energy-dispersive X-ray spectroscopy, transmission electron microscopy, Brunauer-Emmett-Teller) techniques...
March 20, 2024: ACS Environ Au
https://read.qxmd.com/read/38503580/effects-of-different-dietary-fiber-supplement-strategies-on-incidence-of-acute-gastrointestinal-injury-in-icu-patients-a-prospective-observational-study
#8
JOURNAL ARTICLE
Ting Liu, Bin Liu, Yi-Qing Jiang, Omorogieva Ojo, Xiao-Song Jiang, Yu-Yu Wang, Can Wang, Xiao-Hua Wang
OBJECTIVE: This study aimed to explore the effects of dietary fiber (DF) supplement strategies on the incidence of acute gastrointestinal injury (AGI) in critically ill patients. DESIGN: A prospective observational study. SETTING: The study was conducted in the First Affiliated Hospital of Soochow University from April 2021 to March 2023. METHODS: Using a five-day dietary log counted the amount of DF supplement. The best fitting trajectories of DF supplement were determined based on the latent class trajectory modelling (LCTM)...
March 18, 2024: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://read.qxmd.com/read/38502269/5-dextrose-in-ringer-s-lactate-versus-5-dextrose-normal-saline-as-maintenance-intravenous-fluid-therapy-in-children-a-randomised-controlled-trial
#9
JOURNAL ARTICLE
Hemanth Kaviti, Joseph John, Krishna Mohan Gulla, Suchanda Sahu
OBJECTIVES: To estimate the difference in serum chloride levels between children receiving 5% Dextrose in Ringer's Lactate (RLD5) vs. 5% Dextrose Normal Saline (DNS) and to estimate the incidence of dyselectrolytemia, hyperchloremic metabolic acidosis (HCMA), acute kidney injury (AKI) and all-cause mortality in both groups. METHODS: A randomised controlled trial was conducted in non-critically ill children aged 6 mo to 14 y, admitted between August 2021 and July 2022, requiring intravenous fluids...
March 19, 2024: Indian Journal of Pediatrics
https://read.qxmd.com/read/38500964/prison-as-a-driver-of-recent-transmissions-of-multidrug-resistant-tuberculosis-in-callao-peru-a-cross-sectional-study
#10
JOURNAL ARTICLE
Christian Utpatel, Milagros Zavaleta, Daniel Rojas-Bolivar, Andreas Mühlbach, Janet Picoy, Walter Portugal, Ana Esteve-Solé, Laia Alsina, Paolo Miotto, Daniella C Bartholomeu, Jorge Sanchez, Diego F Cuadros, Jorge O Alarcon, Stefan Niemann, Moises A Huaman
BACKGROUND: We sought to identify resistance patterns and key drivers of recent multidrug-resistant tuberculosis (MDR-TB) transmission in a TB-prevalent area in Peru. METHODS: Cross-sectional study including MDR Mycobacterium tuberculosis complex (Mtbc) strains identified in Callao-Peru between April 2017 and February 2019. Mtbc DNA was extracted for whole genome sequencing which was used for phylogenetic inference, clustering, and resistance mutation analyses. Clusters indicative of recent transmission were defined based on a strain-to-strain distance of ≤5 (D5) single nucleotide polymorphisms (SNPs)...
March 2024: Lancet Reg Health Am
https://read.qxmd.com/read/38477224/the-futility-of-post-haemodialysis-blood-glucose-levels-a-retrospective-cohort-study
#11
JOURNAL ARTICLE
Jing Zhang, Richard K Le Leu, Qunyan Xu, Paul Bennett
BACKGROUND: Frequent blood glucose tests are performed for people with diabetes receiving haemodialysis. OBJECTIVES: To determine the rate of out-of-range post-haemodialysis blood glucose levels that are clinically acted upon, the intervention and outcome of each intervention, and the associations between post-haemodialysis blood glucose levels and relevant clinical predictors. DESIGN: 12-month retrospective cohort medical record review in one Australian haemodialysis centre...
March 13, 2024: Journal of Renal Care
https://read.qxmd.com/read/38469102/real-world-evidence-study-finds-no-new-onset-diabetes-or-drug-related-hyperglycemia-in-pompe-disease-patients-treated-with-avalglucosidase-alfa
#12
JOURNAL ARTICLE
Alexandra Dumitriu, Ann Lucas, Raffaella Colzani
Avalglucosidase alfa therapy for Pompe disease is diluted in dextrose 5% solution in water (D5W) for infusion, which raises questions about the potential for hyperglycemia or worsening diabetes. Using United States insurance claims data, we assessed the impact of biweekly infusions on hyperglycemia, new-onset diabetes mellitus, insulin resistance, and prediabetes in patients with Pompe disease. After starting avalglucosidase alfa treatment, 1 of 26 patients had one claim for hyperglycemia, which was attributed to acute pancreatitis...
March 2024: Molecular Genetics and Metabolism Reports
https://read.qxmd.com/read/38467323/synergistic-effects-of-combined-probiotics-bacillus-pumilis-d5-and-leuconostoc-mesenteroide-b4-on-immune-enhancement-and-disease-resistance-in-litopenaeus-vannamei
#13
JOURNAL ARTICLE
Mei-Ying Huang, Bich Ngoc Truong, Tan Phat Nguyen, Huei-Jen Ju, Po-Tsang Lee
This study investigated the effects of two distinct probiotics, Leuconostoc mesenteroides B4 (B4) and Bacillus pumilus D5 (D5), along with their combination, on the diet of white shrimp (Litopenaeus vannamei) during an eight-week feeding trial. The diets tested included B4 + dextran at 107 CFU/g feed (the B4 group), D5 alone at 107 CFU/g feed (the D5 group), and a combination of B4 + dextran and D5 at 5×106 CFU/g feed each (the B4+dextran + D5 group). Relative to the control group, those administered probiotics exhibited moderate enhancements in growth...
March 9, 2024: Developmental and Comparative Immunology
https://read.qxmd.com/read/38464435/evaluation-of-the-efficiency-of-an-ultrasound-supported-infiltration-technique-in-patients-with-tennis-elbow-applying-the-itec-medical-device-a-multicenter-study
#14
JOURNAL ARTICLE
Kathi Thiele, Annemarie Unmann, Stephanie Geyer, Sebastian Siebenlist, Markus Scheibel, Ricarda Seemann, Markus Lerchbaumer, Christian Schoch, Konrad Mader
BACKGROUND: The treatment of lateral epicondylitis remains unsatisfactory in certain cases. The aim of this study is to investigate the efficiency of an ultrasound-guided infiltration combined with fenestration of the extensor tendon postulating a 50% reduction in pain on exertion within 6 months. METHODS: In a prospective, nonrandomized, multicenter study design, 68 patients with chronic lateral epicondylitis and symptoms lasted for at least 6 weeks were included...
March 2024: JSES international
https://read.qxmd.com/read/38458420/increased-circulation-of-echovirus-11-in-the-general-population-and-hospital-patients-as-elicited-by-the-non-polio-enterovirus-laboratory-based-sentinel-surveillance-in-northern-italy-2023
#15
JOURNAL ARTICLE
Laura Pellegrinelli, Cristina Galli, Federica Giardina, Guglielmo Ferrari, Sara Colonia Uceda Renteria, Ferruccio Ceriotti, Arlinda Seiti, Sandro Binda, Antonino Maria Guglielmo Pitrolo, Roberta Schiavo, Sergio Maria Ivano Malandrin, Annalisa Cavallero, Marco Arosio, Claudio Farina, Massimo Oggioni, Pierluigi Congedo, Danilo Cereda, Francesca Rovida, Antonio Piralla, Elena Pariani, Fausto Baldanti
OBJECTIVES: Following the alert of echovirus 11 (E-11) infection in neonates in EU/EEA Member States, we conducted an investigation of E-11 circulation by gathering data from community and hospital surveillance of enterovirus (EV) in northern Italy from August 1st , 2021 to June 30th , 2023. METHODS: Virological results of EVs were obtained from the regional sentinel surveillance database for influenza-like illness (ILI) in outpatients, and from the laboratory database of ten hospitals for inpatients with either respiratory or neurological symptoms...
March 6, 2024: International Journal of Infectious Diseases: IJID
https://read.qxmd.com/read/38457634/first-report-of-panax-notoginseng-leaf-spot-disease-caused-by-boeremia-exigua-in-china
#16
JOURNAL ARTICLE
Qian Zhou, Jian Zhao, Rui Chen, Changlin Zhao
Panax notoginseng a perennial herb native to China, is widely grown in the Yunnan Province. (Yang et al. 2022). From July to August 2022, a new leaf spot disease was observed on fully expanded leaves of P. notoginseng from a planting base in the Xundian, Yunnan Province, China. Approximately 250 ha. of P. notoginseng is the cultivated area, and the incidence of leaf spot disease was around 10-15%. Round spots appeared on the infected leaves and as the disease progressed these leaves fell off the plant. A total 21 symptomatic leaves were randomly collected from the planting base to isolate the pathogens and further study in the laboratory...
March 8, 2024: Plant Disease
https://read.qxmd.com/read/38457633/biological-control-of-rapeseed-clubroot-plasmodiophora-brassicae-using-the-endophytic-fungus-didymella-macrostoma-p2
#17
JOURNAL ARTICLE
Guoqing Li, Junyun Cheng, Tao Luo, Jing Zhang, Mingde Wu, Long Yang, Weidong Chen
Didymella macrostoma P2 was isolated from rapeseed (Brassica napus), and it is an endophyte of rapeseed and an antagonist of three rapeseed pathogens, Botrytis cinerea, Leptosphaeria biglobosa and Sclerotinia sclerotiorum. However, whether or not P2 has a suppressive effect on infection of rapeseed by the clubroot pathogen Plasmodiophora brassicae remains unknown. This study was conducted to detect production of antimicrobials by P2 and to determine efficacy of the antimicrobials and P2 pycnidiospores in suppression of rapeseed clubroot...
March 8, 2024: Plant Disease
https://read.qxmd.com/read/38451349/subacute-exposure-to-gaseous-pollutants-from-diesel-engine-exhaust-attenuates-capsaicin-induced-cardio-pulmonary-reflex-responses-involving-oxidant-stress-mechanisms-in-adult-wistar-rats
#18
JOURNAL ARTICLE
Ravindran Revand, Aditya Dontham, Swarnabha Sarkar, Asmita Patil
Intravenous injection of capsaicin produces vagal-mediated protective cardio-pulmonary (CP) reflexes manifesting as tachypnea, bradycardia, and triphasic blood pressure (BP) response in anesthetized rats. Particulate matter from diesel engine exhaust has been reported to attenuate these reflexes. However, the effects of gaseous constituents of diesel exhaust are not known. Therefore, the present study was designed to investigate the effects of gaseous pollutants in diesel exhaust, on capsaicin-induced CP reflexes in rat model...
March 7, 2024: Cardiovascular Toxicology
https://read.qxmd.com/read/38450161/oral-clostridium-butyricum-on-mice-endometritis-through-uterine-microbiome-and-metabolic-alternations
#19
JOURNAL ARTICLE
Mao Hagihara, Tadashi Ariyoshi, Shuhei Eguchi, Kentaro Oka, Motomichi Takahashi, Hideo Kato, Yuichi Shibata, Takumi Umemura, Takeshi Mori, Narimi Miyazaki, Jun Hirai, Nobuhiro Asai, Nobuaki Mori, Hiroshige Mikamo
Endometritis occurs frequently in humans and animals, which can negatively affect fertility and cause preterm parturition syndrome. Orally administered Clostridium butyricum , a butyrate-producing gram-positive anaerobe, exhibits anti-inflammatory effects. However, the precise mechanism by which Clostridium butyricum attenuates endometritis remains unclear. This in vivo study evaluated the anti-inflammatory effects of orally administered Clostridium butyricum on uterine tissues. In addition, we conducted uterine microbiome and lipid metabolome analyses to determine the underlying mechanisms...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38439877/metatranscriptomics-revealed-the-molecular-characterization-of-circulating-enterovirus-strains-causing-aseptic-meningitis-in-children-in-wuxi-china
#20
JOURNAL ARTICLE
Ying Hua, Zhenyan Lv, Yineng Zhou, Hongxia Xiang, Mingxia Sun, Yan-Jun Kang
Enteroviruses are major etiological agents of aseptic meningitis globally, however information on circulating enterovirus types associated with this disease in Wuxi, China is limited. In this study, cerebrospinal fluid samples were collected from 20 pediatric aseptic meningitis cases in a Wuxi hospital in 2020 and subjected to metagenomic analysis to detect pathogens. Enterovirus B was detected in 9 cases, including 7 echovirus 18 (E18) and 2 echovirus 11 (E11) strains. The E18 strains exhibited 87.5-98.2% nucleotide identity and phylogenetically clustered with other China E18 strains, while the E11 strains showed 97...
March 15, 2024: Heliyon
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