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https://www.readbyqxmd.com/read/28364873/broadening-our-perspectives-on-complementary-and-alternative-medicine-for-menopause-a-narrative-review
#1
REVIEW
Dunia Tonob, Melissa K Melby
Complementary and alternative medicine (CAM) is widely used for menopause, although not all women disclose use to their healthcare providers. This narrative review aims to expand providers' understanding of cross-cultural approaches to treating and managing menopause by providing an overarching framework and perspective on CAM treatments. Increased provider understanding and awareness may improve not only provider-patient communication but also effectiveness of treatments. The distinction between illness (what patients suffer) and disease (what physicians treat) highlights the gap between what patients seek and doctors provide, and may help clarify why many women seek CAM at menopause...
May 2017: Maturitas
https://www.readbyqxmd.com/read/28265850/a-general-description-for-chinese-medicine-in-treating-premature-ovarian-failure
#2
REVIEW
Jing Lin, Xue-Lian Li, Hui Song, Qian Li, Ming-Yan Wang, Xue-Min Qiu, Da-Jin Li, Ling Wang
Premature ovarian failure (POF) is a kind of gynecological disease that causes amenorrhea, infertility, menopause and urogenital symptoms. Currently hormone replacement therapy (HRT) is the most popular choice for women with POF to get rid of menopausal syndrome. However, as the popularization of Chinese herbs made Chinese medicine (CM) shine new lights, physicians are able to treat POF with both meno-herbs and integrated therapy. HRT has its own indications and contraindications. For example, unexplained vaginal bleeding, acute liver damage, liver dysfunction, vascular embolization, and breast cancer are all contraindications of HRT, and CM is taken by more physicians as an adjuvant therapy...
February 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28163116/danggui-buxue-tang-astragali-radix-and-angelicae-sinensis-radix-for-menopausal-symptoms-a-review
#3
REVIEW
Huang Q Lin, Amy Gw Gong, Huai Y Wang, Ran Duan, Tina Tx Dong, Kui J Zhao, Karl Wk Tsim
BACKGROUND: Traditional Chinese medicine (TCM) has contributed greatly to human health in past several thousand years. Today, the development of TCM is facing two obstacles: (i) quality control of herbal extract; and (ii) action mechanisms not known. OBJECTIVES: Among thousands of complex TCM formulations, Danggui Buxue Tang (DBT) is the simplest one. DBT is used to treat ailments in women and contains only two herbs, Astragali Radix (Huangqi; AR) and Angelicae Sinensis Radix (Danggui; ASR)...
February 2, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28111216/rehmanniae-radix-in-osteoporosis-a-review-of-traditional-chinese-medicinal-uses-phytochemistry-pharmacokinetics-and-pharmacology
#4
REVIEW
Chenyue Liu, Rufeng Ma, Lili Wang, Ruyuan Zhu, Haixia Liu, Yubo Guo, Baosheng Zhao, Shangang Zhao, Jinfa Tang, Yu Li, Jianzhao Niu, Min Fu, Dongwei Zhang, Sihua Gao
ETHNOPHARMACOLOGICAL RELEVANCE: Emerging clinical usage and pharmacological effects have been achieved in using Rehmanniae Radix either singly or in combination with other herbs to treat skeletal diseases in traditional Chinese medicine (TCM) in the recent years. This study is aimed to provide a comprehensive review about the historical TCM interpretation of the action of Rehmanniae Radix in osteoporosis, its usage in clinical trials and osteoporotic models, its main phytochemical constituents, and its pharmacokinetics...
January 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28053654/comparison-of-chemical-profiles-and-effectiveness-between-erxian-decoction-and-mixtures-of-decoctions-of-its-individual-herbs-a-novel-approach-for-identification-of-the-standard-chemicals
#5
H P Cheung, S W Wang, T B Ng, Y B Zhang, L X Lao, Z J Zhang, Y Tong, F W S Chung, S C W Sze
BACKGROUND: Identification of bioactive standard chemicals is a major challenge in the study of the Chinese medicinal formula. In particular, the chemical components may interact differently depending on the preparative methods, therefore affecting the amounts of bioactive components and their pharmacological properties in the medicinal formula. With the use of Erxian decoction (EXD) as a study model-a  well-known Chinese medicinal formula for treating menopausal symptoms, a novel and rapid approach in seeking standard chemicals has been established by differentially comparing the HPLC profiles and the menopause-related biochemical parameters of combined decoction of EXD (EXD-C) and mixtures of the decoctions of its individual herbs (EXD-S)...
2017: Chinese Medicine
https://www.readbyqxmd.com/read/27912959/chinese-herbal-medicine-kuntai-capsule-for-treatment-of-menopausal-syndrome-a-systematic-review-of-randomized-clinical-trials
#6
REVIEW
Quan Zhou, Jing Tao, Huamei Song, Aihua Chen, Huaijie Yang, Manzhen Zuo, Hairong Li
OBJECTIVES: Kuntai capsule has been widely used for the treatment of menopausal syndrome in China for long time. We conducted this review to assess efficacy and safety of Kuntai capsule for the treatment of menopausal syndrome. METHODS: We searched studies in PubMed, ClinicalTrials, the Cochrane Library, China National Knowledge Infrastructure Database(CNKI), China Science and Technology Journal Database (VIP), Wan fang Database and Chinese Biomedical Literature Database(CBM) until November 20, 2014...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27871904/steroidogenic-effect-of-erxian-decoction-for-relieving-menopause-via-the-p-akt-pkb-pathway-in-vitro-and-in-vivo
#7
Shi Wei Wang, Ho Pan Cheung, Yao Tong, Jia Lu, Tzi Bun Ng, Yan Bo Zhang, Zhang-Jin Zhang, Kai Fai Lee, Jenny Ka Wing Lam, Stephen Cho Wing Sze
ETHNOPHARMACOLOGICAL RELEVANCE: Erxian decoction (EXD), an empirical Chinese medicine formula, is effectively used in the clinical treatment of menopause-related symptoms in China. Previous data from our group show that EXD has steroidogenic effect on natural menopausal Sprague-Dawley-rats (SD-rats) as an animal model of menopause. However, the mechanistic studies on steroidogenic effects of EXD are still inadequate. Hence, the mechanisms of steroidogenic effects of EXD were studied in vitro and in vivo in this study...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27845267/protective-effects-and-mechanisms-investigation-of-kuntai-capsule-on-the-ovarian-function-of-a-novel-model-with-accelerated-aging-ovaries
#8
Jinjin Zhang, Li Fang, Liangyan Shi, Zhiwen Lai, Zhiyong Lu, Jiaqiang Xiong, Meng Wu, Aiyue Luo, Shixuan Wang
ETHNOPHARMACOLOGICAL RELEVANCE: Kuntai capsule, a traditional Chinese medicine, has been widely used for the clinical treatment of menopausal syndrome. However, its mechanisms remain poorly understood. Considering that aging ovaries are the primary cause of menopause, this study was designed to investigate the effects and mechanisms of Kuntai capsule on ovarian function in a novel mice model with accelerated aging ovaries. MATERIALS AND METHODS: Seventy-five female C57BL/6 mice were chosen for this study...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27760084/effect-of-gua-sha-therapy-on-perimenopausal-syndrome-a-randomized-controlled-trial
#9
Fang Meng, Pei-Bei Duan, Junya Zhu, Qing-Qing Lou, Zhao-Hui Fang, Hong-Li An, Lan-Ying Liu, Yue Hu, Qian Hu
OBJECTIVE: This study aims to evaluate the effectiveness and safety of Gua sha therapy on perimenopausal symptoms, quality of life, and serum female hormones in participants with perimenopausal syndrome. METHODS: A prospective, randomized, controlled clinical trial was conducted at the First Affiliated Hospital of Nanjing University of Chinese Medicine in China. Eighty women with perimenopausal syndrome were recruited and randomized into an intervention group or a control group...
October 10, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27676631/trajectories-of-response-to-acupuncture-for-menopausal-vasomotor-symptoms-the-acupuncture-in-menopause-study
#10
Nancy E Avis, Remy R Coeytaux, Beverly Levine, Scott Isom, Timothy Morgan
OBJECTIVE: To examine the trajectories of responses to acupuncture treatment for menopausal vasomotor symptoms (VMS) and the characteristics of women in each trajectory. METHODS: Two hundred nine perimenopausal and postmenopausal women aged 45 to 60 years experiencing at least four VMS per day were recruited and randomized to receive up to 20 acupuncture treatments within 6 months or to a waitlist control group. The primary outcome was percent change from baseline in the mean daily VMS frequency...
February 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27418936/herbal-medicine-for-hot-flushes-induced-by-endocrine-therapy-in-women-with-breast-cancer-a-systematic-review-and-meta-analysis
#11
REVIEW
Yuanqing Li, Xiaoshu Zhu, Alan Bensussan, Pingping Li, Eugene Moylan, Geoff Delaney, Luke McPherson
Objective. This systematic review was conducted to evaluate the clinical effectiveness and safety of herbal medicine (HM) as an alternative management for hot flushes induced by endocrine therapy in breast cancer patients. Methods. Key English and Chinese language databases were searched from inception to July 2015. Randomized Controlled Trials (RCTs) evaluating the effects of HM on hot flushes induced by endocrine therapy in women with breast cancer were retrieved. We conducted data collection and analysis in accordance with the Cochrane Handbook for Systematic Reviews of Interventions...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27358201/the-application-of-yin-yang-concept-on-heart-rate-variability-patterns-in-menopausal-women-with-insomnia
#12
Yen-Ying Kung, Cheryl C H Yang, Jen-Hwey Chiu, Terry B J Kuo
OBJECTIVE: To develop heart rate variability (HRV) patterns for peri- and postmenopausal insomnia (PI) by the yin/yang concept of Chinese medicine (CM). METHODS: Seventy-four peri- and postmenopausal women (average age 56.6±1.0 years) with insomnia were enrolled in the study. HRV and the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI) were recorded. The Autonomic Nervous System (ANS), Sympathetic and Parasympathetic Indices were derivative from the low frequency (LF), high frequency (HF) and ratio of LF to HF (LF/HF) components of the HRV...
June 29, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27327802/use-of-plant-based-therapies-and-menopausal-symptoms-a-systematic-review-and-meta-analysis
#13
REVIEW
Oscar H Franco, Rajiv Chowdhury, Jenna Troup, Trudy Voortman, Setor Kunutsor, Maryam Kavousi, Clare Oliver-Williams, Taulant Muka
IMPORTANCE: Between 40% and 50% of women in Western countries use complementary therapies to manage menopausal symptoms. OBJECTIVE: To determine the association of plant-based therapies with menopausal symptoms, including hot flashes, night sweats, and vaginal dryness. DATA SOURCES: The electronic databases Ovid MEDLINE, EMBASE, and Cochrane Central were systematically searched to identify eligible studies published before March 27, 2016. Reference lists of the included studies were searched for further identification of relevant studies...
June 21, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27196297/the-estrogenic-properties-of-danggui-buxue-tang-a-chinese-herbal-decoction-are-triggered-predominantly-by-calycosin-in-mcf-7-cells
#14
COMPARATIVE STUDY
Amy G W Gong, Kei M Lau, Miranda L Xu, Huang Q Lin, Tina T X Dong, Ken Y Z Zheng, K J Zhao, Karl W K Tsim
BACKGROUND: Danggui Buxue Tang (DBT), a Chinese herbal decoction containing Astragali Radix (AR; roots of Astragalus memebranaceus (Fisch.) Bunge var. mongholicus (Bunge) Hsiao) and Angelicae Sinensis Radix (ASR; roots of Angelica sinensis Oliv.) at a weight ratio of 5:1, is used to improve menopausal syndromes in women. Several lines of evidence indicate that DBT has strong estrogenic property; however, the action mechanism of this herbal decoction is not known. Calycosin, a major flavonoid in AR, shares similar structure with β-estradiol, and thus which is hypothesized to be the key compound of DBT in responsible for such estrogenic properties...
August 2, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27131879/comparative-analysis-of-proteins-with-stimulating-activity-on-ovarian-estradiol-biosynthesis-from-four-different-dioscorea-species-in-vitro-using-both-phenotypic-and-target-based-approaches-implication-for-treating-menopause
#15
COMPARATIVE STUDY
J Lu, R N S Wong, L Zhang, R Y L Wong, T B Ng, K F Lee, Y B Zhang, L X Lao, J Y Liu, S C W Sze
Rhizomes of Dioscorea species are traditionally used for relieving menopausal syndromes in Chinese medicine. The estrogen-stimulating bioactive principles have been demonstrated in our previous study. In this study, the estrogen-stimulating effects of proteins isolated from four Dioscorea species [D. alata L. (DA), D. zingiberensis C.H. Wright (DH), D. collettii var. hypoglauca (Palib.) S.J. Pei & C.T. Ting (DH), and D. oppositifolia L. (DO)] have been investigated and compared. Microscopic authentication of four Dioscorea species was performed by using paraffin and powder sections of the rhizomes...
September 2016: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/27062798/-discussion-on-strategy-of-treatment-of-perimenopausal-syndrome-with-chinese-and-western-medicine
#16
COMPARATIVE STUDY
Kun Ma, Yan-xia Chen
Perimenopausal syndrome refers to a series of physical and mental symptoms ,caused by the fluctuation of the sex hormones in the menopause, which is one of the common diseases in gynecology. With the acceleration of the aging population ir the world, it has caused the world's attention. Modern medicine has developed rapidly in the field of basic theory and clinical research, but there are still some problems in the treatment. Clinical treatment is mainly in hormone replacement therapy, but there are some potential risks, adverse reactions and many contraindications, thereby reducing patients' compliance and tolerance...
October 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/27040419/traditional-chinese-medicine-valuably-augments-therapeutic-options-in-the-treatment-of-climacteric-syndrome
#17
REVIEW
Sarah Eisenhardt, Johannes Fleckenstein
Climacteric syndrome refers to recurring symptoms such as hot flashes, chills, headache, irritability and depression. This is usually experienced by menopausal women and can be related to a hormonal reorganization in the hypothalamic-pituitary-gonadal axis. In Traditional Chinese Medicine, originating 1000s of years ago, above-mentioned symptoms can be interpreted on the basis of the philosophic diagnostic concepts, such as the imbalance of Yin and Yang, the Zang-Fu and Basic substances (e.g. Qi, Blood and Essence)...
July 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/26976671/chinese-herbal-medicine-for-menopausal-symptoms
#18
REVIEW
Xiaoshu Zhu, Yuklan Liew, Zhao Lan Liu
BACKGROUND: Chinese herbal medicine (CHM) usage is expected to increase as women suffering from menopausal symptoms are seeking alternative therapy due to concerns from the adverse effects (AEs) associated with hormone therapy (HT). Scientific evidence for their effectiveness and safety is needed. OBJECTIVES: To evaluate the effectiveness and safety of CHM in the treatment of menopausal symptoms. SEARCH METHODS: We searched the Gynaecology and Fertility Group's Specialised Register of controlled trials, Cochrane Central Register of Controlled Trials (CENTRAL; 2015, Issue 3), MEDLINE, Embase, CINAHL, AMED, and PsycINFO (from inception to March 2015)...
March 15, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26857875/herbal-medicine-danggui-shaoyao-san-for-treating-primary-dysmenorrhea-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
REVIEW
Hye Won Lee, Ji Hee Jun, Ki-Jung Kil, Byong-Seob Ko, Choong Hwan Lee, Myeong Soo Lee
Danggui Shaoyao San (DSS), a traditional herbal prescription, has long been used to treat menopause-related symptoms, including dysmenorrhea. We conducted a systematic review of randomized controlled trials to evaluate the efficacy of DSS for dysmenorrhea. We searched the following electronic databases through October 2015: PubMed; EMBASE; the Cochrane Library; AMED; five Korean databases (KoreaMed, DBPIA, OASIS, RISS, and KISS); three Chinese databases (CNKI, Wan Fang Database, and VIP), and one Japanese database (CiNii)...
March 2016: Maturitas
https://www.readbyqxmd.com/read/26820757/preclinical-studies-and-clinical-evaluation-of-compounds-from-the-genus-epimedium-for-osteoporosis-and-bone-health
#20
REVIEW
Inthrani Raja Indran, Ryan Lim Zhen Liang, Tan Ee Min, Eu-Leong Yong
The morbidity and mortality associated with fractures due to osteoporosis or "porous bone" contributes significantly to global healthcare costs and will increase exponentially with ageing populations. In menopausal women, the onset of menopause and rapid estrogen withdrawal leads to osteoporotic fractures. Healthy bone requires the coordinated remodeling function of osteoclasts, osteoblasts, and osteocytes in the basic bone multicellular unit, regulated by estrogen, RANKL/OPG, ROS, growth factors, and other kinase signaling pathways...
June 2016: Pharmacology & Therapeutics
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