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"metabolic syndrome", "shift work"

Debora Rosa, Stefano Terzoni, Rosalba Lembo, Anne Destrebecq
AIM: To investigate the prevalence of metabolic syndrome (MS) among nurses, as well as the organizational impact of work-related stress as a consequence of MS among nurses in Italy. To study the organizational models, turnover rates, and job satisfaction among nurses, in a sample of Italian healthcare facilities. BACKGROUND: MS is considered an important metabolic disorder in the modern world, responsible for diseases with economic effects on hospitals. Shift work (SW) seems to be a risk factor for MS, while the Mediterranean diet appears to be protective...
February 2018: Recenti Progressi in Medicina
Nanfu Deng, Taylor P Kohn, Larry I Lipshultz, Alexander W Pastuszak
BACKGROUND: More than 21 million Americans and nearly 20% of the U.S. workforce are shift workers. Non-standard shift work, defined as work that falls outside of 6 am-6 pm, can lead to poor diet, exercise, and sleep habits that lead to decreased productivity, increased workplace accidents, and a variety of negative health outcomes. AIM: To investigate the associations between shift work exposure and chronic medical conditions such as metabolic syndromes, cardiovascular disease, gastrointestinal disturbances, and depression as well as urologic complications including hypogonadism, male infertility, lower urinary tract symptoms, and prostate cancer with a focus on the effects of shift work sleep disorder (SWSD) on the severity of these negative health outcomes...
January 19, 2018: Sexual Medicine Reviews
Roberto Paganelli, Claudia Petrarca, Mario Di Gioacchino
The 2017 Nobel Prize for Physiology or Medicine, awarded for the discoveries made in the past 15 years on the genetic and molecular mechanisms regulating many physiological functions, has renewed the attention to the importance of circadian rhythms. These originate from a central pacemaker in the suprachiasmatic nucleus in the brain, photoentrained via direct connection with melanopsin containing, intrinsically light-sensitive retinal ganglion cells, and it projects to periphery, thus creating an inner circadian rhythm...
2018: Clinical and Molecular Allergy: CMA
Osamu Itani, Yoshitaka Kaneita, Mikiko Tokiya, Maki Jike, Atsushi Murata, Sachi Nakagome, Yuichiro Otsuka, Takashi Ohida
BACKGROUND: This longitudinal study investigated the effects of various lifestyle-related factors - including sleep duration, shift work, and actual days taken off work - on new-onset metabolic syndrome (MetS). METHODS AND RESULTS: A total of 39,182 male employees (mean age 42.4 ± 9.8 years) of a local government organization in Japan were followed up for a maximum of seven years, between 1999 and 2006. Multivariate analysis (Cox proportional hazard method) identified seven high-risk lifestyle factors that were significantly associated with new-onset MetS or a range of metabolic factors (obesity, hypertension, hyperglycemia, dyslipidemia): (1) short sleep duration (<5 h/day), (2) shift work, (3) insufficient number of days off work, (4) always eating until satiety, (5) not trying to take every opportunity to walk, (6) alcohol intake ≥60 g/day, and (7) smoking...
November 2017: Sleep Medicine
Yung-Chuan Lu, Chao-Ping Wang, Teng-Hung Yu, I-Ting Tsai, Wei-Chin Hung, I-Cheng Lu, Chia-Chang Hsu, Wei-Hua Tang, Jer-Yiing Houng, Fu-Mei Chung, Mei-Chu Yen Jean
AIMS: There is increasing evidence linking a shift work schedule with various adverse health effects. The present study aimed to examine the relationship between shift work and the metabolic syndrome (MetS) in male steel workers, and also the possible mechanism of shift work-related metabolic derangements. METHODS: A total of 1732 men aged 42 ± 8 years were enrolled in this cross-sectional study, including 862 day workers and 870 shift workers. Circulating levels of resistin were measured by ELISA using monoclonal specific antibodies...
2017: Diabetology & Metabolic Syndrome
Stephen M James, Kimberly A Honn, Shobhan Gaddameedhi, Hans P A Van Dongen
PURPOSE OF REVIEW: Our 24/7 society is dependent on shift work, despite mounting evidence for negative health outcomes from sleep displacement due to shift work. This paper reviews short- and long-term health consequences of sleep displacement and circadian misalignment due to shift work. RECENT FINDINGS: We focus on four broad health domains: metabolic health; risk of cancer; cardiovascular health; and mental health. Circadian misalignment affects these domains by inducing sleep deficiency, sympathovagal and hormonal imbalance, inflammation, impaired glucose metabolism, and dysregulated cell cycles...
June 2017: Current Sleep Medicine Reports
Jae-Il Oh, Hyeon Woo Yim
This study aimed to analyze the association between the shift work schedule and metabolic syndrome (MetS). This is a retrospective longitudinal study based on the 2015 health checkup data of 2,090 workers evaluated for MetS in 2010 at a general hospital in Korea. The participants were divided according to their shift work schedule into daytime, three-shift (8-h rotation), and two-shift (12-h rotation) workers. The index that indicates the association between the shift work schedule and MetS is the odds ratio (OR) calculated using multivariate logistic regression...
February 7, 2018: Industrial Health
Deepa Burman
Shift work sleep disorder is a common problem in industrialized countries because of the need for occupations and services to continue to function 24 hours/day. Approximately 20% of employed adults in the United States are engaged in shift work. Shift work sleep disorder is diagnosed if there is a report of insomnia or excessive sleepiness for at least 3 months associated with a recurring work schedule that overlaps the usual time for sleep. Shift work is associated with an increased occurrence of metabolic disorders, such as insulin resistance, diabetes, dyslipidemia, and metabolic syndrome, and it has been implicated in weight gain and cognitive impairment...
September 2017: FP Essentials
Jill Korsiak, Joan Tranmer, Andrew Day, Kristan J Aronson
OBJECTIVES: The main objective was to determine whether sleep duration on work shifts mediates the relationship between a current alternating day and night shift work schedule and metabolic syndrome among female hospital employees. The secondary objective was to assess whether cumulative lifetime shift work exposure was associated with metabolic syndrome. METHODS: In this cross-sectional study of 294 female hospital employees, sleep duration was measured with the ActiGraph GT3X+...
February 2018: Occupational and Environmental Medicine
Motahareh Kheradmand, Zhila Maghbooli, Sedigheh Salemi, Mahnaz Sanjari
BACKGROUND: The insulin resistance syndrome is one of the major contributors of metabolic syndrome, diabetes Type 2 and atherosclerotic cardiovascular disease. A common mutation (677C to T; Ala to Val) in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with decreased specific MTHFR activity and elevation of the homocysteine. The aim of this study is investigation of association between MTHFR 677C > T polymorphism with insulin resistance by using HOMA (Homeostasis Model Assessment) index in nurses who are potentially prone to develop insulin resistance because of unfavorable effects of shift work...
2017: Journal of Diabetes and Metabolic Disorders
David Rabinerson, Lizy Markovitch, Rinnat Gabbay-Ben-Ziv
Work in repeated changing shifts, in general, and night-shifts, in particular, is considered a necessity, encompassing many professions, among them physicians and nurses. This type of work has been shown to adversely affect the normal function of the human body circadian rhythm. This negative influence in turn, is considered to increase characteristic types of morbidity such as metabolic syndrome, type 2 diabetes and increased rate of cardiovascular morbidity. Women working in night-shifts in particular, have been found to face increased rates of breast cancer, as well as menstrual disturbances and decreased fertility...
July 2016: Harefuah
Kyoung Hwa Yu, Yu Hyeon Yi, Yun Jin Kim, Byung Mann Cho, Sang Yeoup Lee, Jeong Gyu Lee, Dong Wook Jeong, So Yeon Ji
BACKGROUND: Shift work is associated with health problems, including metabolic syndrome. This study investigated the association between shift work and metabolic syndrome in young workers. METHODS: A total of 3,317 subjects aged 20-40 years enrolled in the 2011-2012 Korean National Health and Nutrition Examination Survey were divided into shift and day workers. We conducted a cross-sectional study and calculated odds ratios using multivariate logistic regression analysis in order to examine the association between shift work and metabolic syndrome...
March 2017: Korean Journal of Family Medicine
W W Tigbe, M H Granat, N Sattar, M E J Lean
BACKGROUND: The relationship between metabolic risk and time spent sitting, standing and stepping has not been well established. The present study aimed to determine associations of objectively measured time spent siting, standing and stepping, with coronary heart disease (CHD) risk. METHODS: A cross-sectional study of healthy non-smoking Glasgow postal workers, n=111 (55 office workers, 5 women, and 56 walking/delivery workers, 10 women), who wore activPAL physical activity monitors for 7 days...
May 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Thunyarat Anothaisintawee, Dumrongrat Lertrattananon, Sangsulee Thamakaison, Kristen L Knutson, Ammarin Thakkinstian, Sirimon Reutrakul
The circadian system is known to play a role in glucose metabolism. Chronotype reflects the interindividual variability in the phase of entrainment. Those with later chronotype typically prefer later times in the day for different activities such as sleep or meals. Later chronotype has been shown to be associated with metabolic syndrome, increased diabetes risk and poorer glycemic control in type 2 diabetes patients. In addition, "social jetlag", a form of circadian misalignment due to a mismatch between social rhythms and the circadian clock, has been shown to be associated with insulin resistance...
2017: Chronobiology International
Amy C Reynolds, Jessica L Paterson, Sally A Ferguson, Dragana Stanley, Kenneth P Wright, Drew Dawson
Prevalence and impact of metabolic disease is rising. In particular, overweight and obesity are at epidemic levels and are a leading health concern in the Western world. Shift work increases the risk of overweight and obesity, along with a number of additional metabolic diseases, including metabolic syndrome and type 2 diabetes (T2D). How shift work contributes to metabolic disease has not been fully elucidated. Short sleep duration is associated with metabolic disease and shift workers typically have shorter sleep durations...
July 11, 2016: Sleep Medicine Reviews
Tiffany Fleet, Erin Stashi, Bokai Zhu, Kimal Rajapakshe, Kathrina L Marcelo, Nicole M Kettner, Blythe K Gorman, Cristian Coarfa, Loning Fu, Bert W O'Malley, Brian York
Circadian rhythmicity is a fundamental process that synchronizes behavioral cues with metabolic homeostasis. Disruption of daily cycles due to jet lag or shift work results in severe physiological consequences including advanced aging, metabolic syndrome, and even cancer. Our understanding of the molecular clock, which is regulated by intricate positive feedforward and negative feedback loops, has expanded to include an important metabolic transcriptional coregulator, Steroid Receptor Coactivator-2 (SRC-2), that regulates both the central clock of the suprachiasmatic nucleus (SCN) and peripheral clocks including the liver...
October 2016: Journal of Biological Rhythms
Nafiseh Shokri Mashhadi, Saeed Saadat, Mohammad Reza Afsharmanesh, Saeed Shirali
AIMS: The circadian system influences on health and metabolic function that can cause raising some risk factor of metabolic syndrome. Few studies have examined data that incorporate the full complexity of daily beverage intake pattern on lipid profiles. The purpose of this study was to investigate relation between daily water and beverage intake of adults working in day or shift work and lipid profile. MATERIALS AND METHODS: Total beverages intake was estimated in shift and administrative staff of Ahvaz International Airport, Iran...
October 2016: Diabetes & Metabolic Syndrome
Anne B Hansen, Leslie Stayner, Johnni Hansen, Zorana J Andersen
OBJECTIVES: Night shift work has been associated with poor sleep, weight gain, metabolic syndrome, which are recognised risk factor for diabetes. However, only a few studies have examined the effect of shift work on diabetes risk. Here, we study the association between shift work and incidence of diabetes in Danish nurses. METHODS: We used the Danish Nurse Cohort with 28,731 participating female nurses recruited in 1993 (19,898) or 1999 (8833), when self-reported baseline information on diabetes prevalence, lifestyle and working time were collected, and followed them in the Danish Diabetes Register for incidence of diabetes until 2013...
April 2016: Occupational and Environmental Medicine
Heath G Gasier, Colin R Young, Erin Gaffney-Stomberg, Douglas C McAdams, Laura J Lutz, James P McClung
Confined space, limited exercise equipment, rotating shift work and reduced sleep may affect cardiometabolic health in submariners. To test this hypothesis, 53 male U.S. Submariners (20-39 years) were studied before and after a 3-month routine submarine patrol. Measures included anthropometrics, dietary and physical activity, biomarkers of cardiometabolic health, energy and appetite regulation, and inflammation. Before deployment, 62% of submariners had a body fat % (BF%) ≥ 25% (obesity), and of this group, 30% met the criteria for metabolic syndrome...
February 9, 2016: Nutrients
Eman Alefishat, Rana Abu Farha
OBJECTIVE: Shift work is associated with higher risk of metabolic disturbances and cardiovascular diseases. There are contradictory reports on the effect of shift work on lipid parameters in the literature. No studies have investigated any possible association between shift work and the ratio of serum triglyceride to high density lipoprotein cholesterol (TG/HDL-C ratio). This ratio can be used as a predictor for insulin resistance. The main aim of the present cross-sectional study was to investigate the association between shift work and serum TG/HDL-C ratio, TG level, and HDL-C level...
November 2015: Metabolic Syndrome and related Disorders
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