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https://www.readbyqxmd.com/read/27920838/successful-resynchronization-by-permanent-his-bundle-pacing-in-a-patient-with-pacing-induced-cardiomyopathy
#1
Yoji Iida, Tomoaki Izawa, Chikara Kobari, Toru Yatsuhashi, Nobuyuki Makishima
Right ventricular (RV) pacing has been reported to result in ventricular dyssynchrony, heart failure, and increased mortality. Pacing associated deterioration of left ventricular (LV) systolic function has been termed pacing-induced cardiomyopathy (PICM). While upgrading to biventricular pacing (BiVP) is an effective therapy for PICM, permanent His-bundle pacing (HBP) can be a physiological alternative to BiVP. We present a patient with PICM who responded dramatically to permanent HBP.
December 2016: Journal of Arrhythmia
https://www.readbyqxmd.com/read/27911256/a-residue-located-at-the-junction-of-the-head-and-stalk-regions-of-measles-virus-fusion-protein-regulates-membrane-fusion-by-controlling-conformational-stability
#2
Yuto Satoh, Saeka Yonemori, Mitsuhiro Hirose, Hiroko Shogaki, Hiroshi Wakimoto, Yoshinori Kitagawa, Bin Gotoh, Tsuyoshi Shirai, Ken-Ichi Takahashi, Masae Itoh
The fusion (F) protein of measles virus (MV) performs refolding from the thermodynamically metastable prefusion form to the highly stable postfusion form via an activated unstable intermediate stage, to induce membrane fusion. Some amino acids involved in the fusion regulation cluster in the heptad repeat B (HR-B) domain of the stalk region, among which substitution of residue 465 by various amino acids revealed that fusion activity correlates well with its side chain length from the Cα (p<0.01) and van der Waals volume (p<0...
December 1, 2016: Journal of General Virology
https://www.readbyqxmd.com/read/27909532/ajmaline-challenge-to-unmask-infrahisian-disease-in-patients-with-recurrent-and-unexplained-syncope-preserved-ejection-fraction-with-or-without-conduction-abnormalities-on-surface-ecg
#3
Francesco Pentimalli, Luca Bacino, Matteo Ghione, Giambattista Siri, Massimo Gazzarata, Paolo Bellotti
Background: Pharmacological challenge with class I antiarrhythmic drug is a recommended diagnostic test in patients with unexplained syncope only in the presence of bundle branch block, when non-invasive tests have failed to make the diagnosis. Its role in patients with minor or no conduction disturbances on 12-leads ECG has not been evaluated yet. It is also not clear which are the values of His-Ventricular interval to be considered diagnostic. We sought to evaluate the role of ajmaline challenge in unmasking the presence of an infrahisian disease in patients with recurrent and unexplained syncope, regardless of the existence of conduction disturbances on surface ECG...
August 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27906656/his-bundle-refractoriness
#4
Samuel J Asirvatham, William G Stevenson
No abstract text is available yet for this article.
November 2016: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/27890282/selective-versus-non-selective-his-bundle-pacing-for-cardiac-resynchronization-therapy
#5
REVIEW
Gaurav A Upadhyay, Roderick Tung
Cardiac resynchronization therapy (CRT) has an established role in the device-based therapy for patients with systolic dysfunction and intraventricular conduction delay, particularly left bundle branch block (LBBB). Recently, His bundle pacing (HBP) has emerged as a viable alternative for resynchronization which can successfully narrow surface QRS and improve mechanical dyssynchrony. The role of selective (i.e., an isoelectric His-paced to QRS interval similar to native HV interval) versus non-selective capture (i...
October 18, 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27867531/steroid-pulse-therapy-was-effective-for-cardiac-sarcoidosis-with-ventricular-tachycardia-and-systolic-dysfunction
#6
Toshitaka Okabe, Tadayuki Yakushiji, Michiaki Hiroe, Yuji Oyama, Wataru Igawa, Morio Ono, Takehiko Kido, Seitaro Ebara, Kennosuke Yamashita, Myong Hwa Yamamoto, Shigeo Saito, Koichi Hoshimoto, Amemiya Kisaki, Naoei Isomura, Hiroshi Araki, Masahiko Ochiai
A 32-year-old man presented with palpitation. He was diagnosed with pulmonary sarcoidosis by lung biopsy. The electrocardiogram showed first-degree atrioventricular block and complete right bundle branch block (CRBBB). We planned to examine laboratory data, echocardiography, Holter monitoring, and gallium-67 scintigraphy. Before he went through all these exams, he developed ventricular tachycardia. After defibrillation was performed, his electrocardiogram revealed complete atrioventricular block. We observed elevation of serum angiotensin-converting enzyme levels...
December 2016: ESC Heart Failure
https://www.readbyqxmd.com/read/27842698/efficacy-and-safety-of-catheter-ablation-of-atrial-tachycardia-through-a-direct-approach-from-noncoronary-sinus-of-valsalva
#7
Mauro Toniolo, Luca Rebellato, Stefano Poli, Elisabetta Daleffe, Alessandro Proclemer
Noncoronary aortic cusp (NCAC) in the aorta represents a challenging location for catheter ablation of focal atrial tachycardias (ATs) arising near the His-bundle region. The purpose of this study was to provide an updated report on the methods, efficacy, and safety of catheter ablation of ATs originating from NCAC. The study population includes 23 patients (18 women [78%], mean age 65 ± 12 years) with highly symptomatic AT. The atrial mapping was performed during tachycardia to define the earliest atrial activation site...
October 20, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27815796/accessory-pathway-location-affects-brain-natriuretic-peptide-level-in-patients-with-wolff-parkinson-white-syndrome
#8
Yosuke Nakatani, Koji Kumagai, Shigeto Naito, Kohki Nakamura, Kentaro Minami, Masahiro Nakano, Takehito Sasaki, Koichiro Kinugawa, Shigeru Oshima
PURPOSE: The purpose of this study was to investigate the relationship between the accessory pathway location and brain natriuretic peptide (BNP) level in patients with Wolff-Parkinson-White (WPW) syndrome. METHODS: We divided 102 WPW syndrome patients with normal left ventricular systolic function into four groups: those with manifest right (MR, n = 14), manifest septal (MS, n = 11), manifest left (ML, n = 30), and concealed (C, n = 47) accessory pathways...
November 4, 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/27797979/prognosis-assessment-of-persistent-left-bundle-branch-block-after-tavi-by-an-electrophysiological-and-remote-monitoring-risk-adapted-algorithm-rationale-and-design-of-the-multicentre-lbbb-tavi-study
#9
Grégoire Massoullié, Pierre Bordachar, Didier Irles, Christophe Caussin, Antoine Da Costa, Pascal Defaye, Frédéric Jean, Alexis Mechulan, Pierre Mondoly, Géraud Souteyrand, Bruno Pereira, Sylvain Ploux, Romain Eschalier
INTRODUCTION: Percutaneous aortic valve replacement (transcatheter aortic valve implantation (TAVI)) notably increases the likelihood of the appearance of a complete left bundle branch block (LBBB) by direct lesion of the LBB of His. This block can lead to high-grade atrioventricular conduction disturbances responsible for a poorer prognosis. The management of this complication remains controversial. METHOD AND ANALYSIS: The screening of LBBB after TAVI persisting for more than 24 hours will be conducted by surface ECG...
October 26, 2016: BMJ Open
https://www.readbyqxmd.com/read/27790494/masquerading-bundle-branch-block-a-poor-prognostic-sign-revisited
#10
Suheil Dhanse, Hashir Kareem, Tom Devasia, Mugula Sudhakar Rao
Masquerading bundle branch block is a rare but important finding on the Electrocardiogram (ECG). It is an indication of severe and diffuse conduction system disease and usually indicates poor prognosis. The precordial leads show a Right Bundle Branch Block (RBBB) pattern while the limb leads resemble a Left Bundle Branch Block (LBBB). This finding on an ECG is almost invariably associated with severe underlying heart disease. It is extremely important to be aware of this finding as it is a marker of poor cardiac outcomes...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27789001/trade-off-between-elimination-of-premature-ventricular-complexes-and-loss-of-synchronized-left-ventricular-pacing-improved-cardiac-function-in-a-patient-with-heart-failure
#11
Hideyuki Hasebe, Masataka Iida, Naoki Hatano, Toshiro Muramatsu
Synchronized left ventricular pacing (sLVP) via adaptive cardiac resynchronization therapy (aCRT) algorithm might enhance the efficacy of CRT. A 71-year-old female was admitted with the diagnosis of heart failure. Electrocardiograms revealed left bundle branch block with QRS width of 144 ms, and frequent premature ventricular complexes (PVCs). A CRT device was implanted, and sLVP via a CRT algorithm was provided. Frequent PVCs arising from the His-bundle suppressed effective sLVP percentage. Radiofrequency application at the His-bundle successfully eliminated the PVCs, but induced complete atrioventricular (AV) block, leading to loss of sLVP...
May 2016: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/27788993/av-nodal-ablation-in-tricuspid-atresia-anatomical-challenges
#12
Jeffrey Munro, Krishnaswamy Chandrasekaran, Komandoor Srivathsan
Patients with congenital heart disease often present unique challenges, especially in the electrophysiology laboratory. Here we present a case of a patient with medically refractory symptomatic atrial tachycardia, tricuspid atresia and a history of a modified Fontan procedure. The approach of an AV node ablation for palliation in our patient was met with challenges in identification of a His-bundle recording and successful ablation after identification of the His-bundle recording from a left sided approach...
May 2016: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/27778351/his-bundle-pacing-full-circle-and-maybe-a-bullseye
#13
John D Fisher
In the words of the legendary late John Messenger, pacemakers have evolved from the equivalent of a pirate's peg leg that simply prevents you from falling down, to a fully articulated prosthesis. Each "ultimate" step has been succeeded by ever more sophisticated devices. Very early attempts at providing atrioventricular synchrony included metal wire connections between atrium and ventricle, and His bundle pacing with large screw-in electrodes. These efforts failed, largely because of poor conductivity, excessive fibrosis and loss of capture...
October 24, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27778339/permanent-his-bundle-pacing-an-adolescent-with-promise
#14
EDITORIAL
James P Daubert
No abstract text is available yet for this article.
October 24, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27764240/feasibility-of-in-vivo-simulation-of-acute-hemodynamics-in-human-atrial-fibrillation
#15
Marek Sramko, Dan Wichterle, Josef Kautzner
This study evaluated hemodynamic feasibility and reproducibility of a new method for in vivo simulation of human atrial fibrillation (AF). The method was tested during sinus rhythm in 10 patients undergoing catheter ablation for AF. A simple electronic device was assembled that allowed triggering a cardiac stimulator by predefined series of RR intervals. Irregular RR interval sequences with a mean heart rate of 90/min and 130/min were obtained from ECG recordings of another patients with AF. Simultaneous atrioventricular pacing was delivered by catheters placed inside the coronary sinus and at the His bundle region...
2016: PloS One
https://www.readbyqxmd.com/read/27752457/hypertrophic-scar-of-the-conjunctiva-presenting-as-an-eyelid-mass-an-unusual-complication-after-surgical-treatment-of-a-chalazion
#16
Jun Hyuk Son, Joon Hyuk Choi, Su-Ho Lim
PURPOSE: To present a rare case of a conjunctival hypertrophic scar presenting as eyelid mass after surgical treatment of a chalazion. CASE PRESENTATION: A 74-year-old man visited our clinic with severe ocular discomfort and excessive lacrimation since several months in his left eye accompanied by itching of the upper eyelid. Examination of the anterior segment revealed a 6 mm (horizontal) × 8 mm (vertical) round, immobile, hard, mushroom-shaped protruding mass on the tarsal conjunctiva of his left eye...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27740897/septal-atrioventricular-junction-region-comprehensive-imaging-in-adults
#17
Farhood Saremi, Cameron Hassani, Damián Sánchez-Quintana
The septal atrioventricular junction is a centrally located region of the heart where the septal components of the atria and ventricles meet the aortic, mitral, and tricuspid valves. Important structures in this region include the membranous septum, the central fibrous body, the Koch triangle, the inferior pyramidal space, and the base of the interventricular septum. This small area is the home of the atrioventricular node and the atrioventricular conduction axis and has enormous importance to electrophysiologists owing to its prime role in the conduction system of the heart...
October 14, 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27729344/non-reentrant-fascicular-tachycardia-clinical-and-electrophysiological-characteristics-of-a-distinct-type-of-idiopathic-ventricular-tachycardia
#18
Ahmed Karim Talib, Akihiko Nogami, Itsuro Morishima, Yasushi Oginosawa, Kenji Kurosaki, Shinya Kowase, Yuki Komatsu, Kenji Kuroki, Miyako Igarashi, Yukio Sekiguchi, Kazutaka Aonuma
BACKGROUND: The most common form of idiopathic Purkinje-related ventricular tachycardia (VT) is the reentrant type. We describe the clinical and electrophysiological characteristics of focal non-reentrant fascicular tachycardia. METHODS AND RESULTS: Among 530 idiopathic VT patients who were referred for ablation, we identified 15 (2.8%) with non-reentrant fascicular tachycardia (11 men, 45±21 years). Sinus rhythm ECG showed normal conduction intervals with a His-ventricular interval of 41±4 ms...
October 2016: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/27722091/hyper-response-to-cardiac-resynchronization-with-permanent-his-bundle-pacing-is-parahisian-pacing-sufficient
#19
Olujimi A Ajijola, Jorge Romero, Gabriel Vorobiof, William M Suh, Kalyanam Shivkumar, Roderick Tung
No abstract text is available yet for this article.
November 2015: HeartRhythm Case Reports
https://www.readbyqxmd.com/read/27720211/history-of-his-bundle-pacing
#20
Gopi Dandamudi, Pugazhendhi Vijayaraman
Chronic right ventricular (RV) pacing has been shown over the years to exert detrimental physiological changes including increased risk for heart failure and atrial fibrillation. His bundle pacing offers the promise of physiological activation of the ventricular tissue, with the potential for reducing the detrimental effects of RV pacing. We describe His bundle pacing in a historical context and briefly highlight several clinical trials that have helped shape the landscape of permanent His bundle pacing.
September 24, 2016: Journal of Electrocardiology
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