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https://www.readbyqxmd.com/read/29326870/lyme-carditis-with-isolated-left-bundle-branch-block-and-myocarditis-successfully-treated-with-oral-doxycycline
#1
Burke A Cunha, Maekal Elyasi, Prince Singh, Ismail Jimada
Lyme disease may present with a variety of cardiac manifestations ranging from first degree to third degree heart block. Cardiac involvement with Lyme disease may be asymptomatic, or symptomatic. Atrioventrical conduction abnormalities are the most common manifestation of Lyme carditis. Less common, are alternating right bundle branch block (RBBB) and left bundle branch block (LBBB). We present an interesting case of a young male whose main manifestation of Lyme carditis was isolated LBBB. He also had mild Lyme myocarditis...
2018: IDCases
https://www.readbyqxmd.com/read/29315453/a-partial-posterior-bundle-ulnar-collateral-ligament-tear-in-a-10-year-old-boy
#2
Todd P Pierce, Jennifer Kurowicki, Kimona Issa, Anthony Festa, Vincent K McInerney, Anthony J Scillia
Medial-sided elbow pain is becoming more common among pediatric overhead sport athletes. One potential cause of this is a partial or complete tear of the ulnar collateral ligament (UCL). Because the growth plate remains open in many of these athletes, the most common injury experienced is an avulsion at the medial epicondyle. However, although rare, there is a potential to tear the UCL, with the most common tears occurring at the anterior bundle. However, tears to the posterior bundle are quite rare in pediatric patients...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29282193/plantar-fibromatosis-in-a-mentally-challenged-man-treated-with-intralesional-corticosteroids
#3
Ayse Serap Karadag, Emin Ozlu, Ayse Bahar Ceyran, Mehmet Simsek, Tugba Kevser Uzuncakmak, Ilkin Zindancı, Necmettin Akdeniz
A 21-year-old mentally challenged man presented with a fixed plaque lesion on the right foot, which had been present for 10 years. Dermatologic examination revealed an erythematous, painful, firm, fixed plaque-nodular lesion on the plantar aspect of the right foot (Figure 1A). Nothing of distinction was noted from his family history or his laboratory tests. An incisional biopsy revealed parallel, regular bundles composed of uniform, plump spindle cells. Thin collagen fibers were seen in contact with and located between the spindle cells...
2017: Skinmed
https://www.readbyqxmd.com/read/29277686/accurate-localization-and-catheter-ablation-of-superoparaseptal-accessory-pathways
#4
Qiang Liu, Michael Shehata, David Z Lan, Ashkan Ehdaie, Eugenio Cingolani, Sumeet S Chugh, Guosheng Fu, Chenyang Jiang, Xunzhang Wang
BACKGROUND: There remains some confusion delineating the accurate location and the detailed anatomic relationship between atrioventricular accessory pathways (APs) located in the superoparaseptal region. OBJECTIVE: To detail the anatomic relationship and accurate location of APs located in the superoparaseptal region. METHODS: Between 2009 and 2016, 11 patients with superoparaseptal accessory pathways (SPS-APs) were identified in 129 consecutive patients who underwent catheter ablation for APs in our center...
December 22, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29277685/cardiac-rhythm-and-pacemaking-abnormalities-in-patients-affected-by-endemic-pemphigus-in-colombia-may-be-a-result-of-deposition-of-autoantibodies-complement-fibrinogen-and-other-molecules
#5
Ana Maria Abreu Velez, Michael S Howard, Jorge Enrique Velazquez-Velez
BACKGROUND: We showed that one third of the patients affected by endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre-EPF) display autoreactivity to the heart. OBJECTIVE: We aim to investigate rhythm disturbances with presence of autoantibodies and correlate them with electrocardiographic changes in these patients. METHODS: We performed a study comparing 30 patients and 30 controls from the endemic area, matched by demographics including age, sex and weight; work activities, comorbidities, among other variables...
December 22, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29274474/permanent-his-bundle-pacing-long-term-lead-performance-and-clinical-outcomes
#6
Pugazhendhi Vijayaraman, Angela Naperkowski, Faiz A Subzposh, Mohamed Abdelrahman, Parikshit S Sharma, Jess W Oren, Gopi Dandamudi, Kenneth A Ellenbogen
BACKGROUND: Right ventricular pacing (RVP) is associated with heart failure and increased mortality. His bundle pacing (HBP) is a physiological alternative to RVP. OBJECTIVE: The aim of our study is to report long-term performance and compare the clinical outcomes of permanent HBP to RVP. METHODS: All patients requiring pacemaker implantation underwent attempt at permanent HBP in 2011 at one hospital and RV pacing at the sister hospital. Patients were followed from implantation, 2 weeks, 2 months and yearly for 5 years...
December 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29258620/refractory-ventricular-fibrillations-after-surgical-repair-of-atrial-septal-defects-in-a-patient-with-cacna1c-gene-mutation-case-report
#7
Ai Kojima, Fumiaki Shikata, Toru Okamura, Takashi Higaki, Seiko Ohno, Minoru Horie, Shunji Uchita, Yujiro Kawanishi, Kenji Namiguchi, Takumi Yasugi, Hironori Izutani
BACKGROUND: Congenital long QT syndrome (LQTS) can cause ventricular arrhythmic events with syncope and sudden death resulting from malignant torsades de pointes (TdP) followed by ventricular fibrillations (VFs). However, the syndrome is often overlooked prior to the development of arrhythmic events in patients with congenital heart diseases demonstrating right bundle branch block on electrocardiogram (ECG). We present a case of an adult patient with congenital heart disease who developed VFs postoperatively, potentially due to his mutation in a LQTS related gene, which was not identified on preoperative assessment due to incomplete evaluation of his family history...
December 19, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29249157/de-novo-design-of-tetranuclear-transition-metal-clusters-stabilized-by-hydrogen-bonded-networks-in-helical-bundles
#8
Shao-Qing Zhang, Marco Chino, Lijun Liu, Youzhi Tang, Xiaozhen Hu, William F DeGrado, Angela Lombardi
De novo design provides an attractive approach to test the mechanism by which metalloproteins define the geometry and reactivity of their metal ion cofactors. While there has been considerable progress in designing proteins that bind transition metal ions including iron-sulphur clusters, the design of tetranuclear clusters with oxygen-rich environments has not been accomplished. Here, we describe the design of tetranuclear clusters, consisting of four Zn2+ and four carboxylate oxygens situated at the vertices of a distorted cube-like structure...
December 18, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29237553/the-snp-rs4252548-r112h-which-is-associated-with-reduced-human-height-compromises-the-stability-of-il-11
#9
Juliane Lokau, Sascha Göttert, Philipp Arnold, Stefan Düsterhöft, David Massa López, Joachim Grötzinger, Christoph Garbers
Height is a complex human phenotype that is influenced by variations in a high number of genes. Recently, a single nucleotide polymorphism (SNP) within IL11 (rs4252548) has been described to be associated with height in adults of European ancestry. This coding SNP leads to the exchange of Arg-112 to His-112 within the cytokine Interleukin-11 (IL-11), which has a well-established role in osteoclast development and bone turnover. The functional consequences of the R112H mutation are unknown so far. In this study, we show by molecular replacement that Arg-112 does not participate in binding of IL-11 to its receptors IL-11R and glycoprotein 130 (gp130)...
December 10, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29226896/recovery-of-cardiomyopathy-induced-by-ventricular-premature-beats-of-parahisian-origin-after-successful-radiofrequency-catheter-ablation
#10
Gökhan Aksan, Ali Elitok, Mehmet Tezcan, Ahmet Kaya Bilge, Kamil Adalet
A 51-year-old male patient presented with frequent and symptomatic premature ventricular complexes (PVCs) that had induced cardiomyopathy. Radiofrequency (RF) catheter ablation of the origin of the PVCs was planned and the patient underwent electrophysiological study. During activation mapping, the earliest ventricular activation was identified at the His bundle region. Small His bundle electrogram recording by the distal ablation electrode during sinus rhythm revealed that the earliest ventricular activation during PVC preceded the QRS onset by 58 milliseconds...
December 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29225866/magnetic-guided-catheter-ablation-of-twin-av-nodal-reentrant-tachycardia-in-a-patient-with-left-atrial-isomerism-interrupted-inferior-vena-cana-and-kawashima-fontan-procedure
#11
Francis Bessière, François-Pierre Mongeon, Judith Therrien, Paul Khairy
Twin AV nodal reentrant tachycardia most commonly occurs in patients with complex congenital heart disease who have two distinct AV nodes, His bundles, and non-preexcited QRS morphologies. Catheter ablation of the weaker AV node may be hindered by anatomical complexities. In such cases, remote magnetic guidance offers a potentially effective solution.
December 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29220422/atrioventricular-node-ablation-and-his-bundle-pacing
#12
Pugazhendhi Vijayaraman, Faiz A Subzposh, Angela Naperkowski
Aims: Atrioventricular node ablation (AVNA) and right ventricular pacing (RVP) are effective therapies for patients with atrial fibrillation (AF) and rapid ventricular rates. His bundle pacing (HBP) is a physiologic alternative to RVP. The aim of our study is to assess the feasibility and safety of HBP in patients undergoing AVNA and its effect on left ventricular (LV) function. Methods and results: Permanent HBP is the preferred form of ventricular pacing at our institute...
December 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29194653/electrophysiological-markers-predicting-impeding-av-block-during-ablation-of-atrioventricular-nodal-re-entry-tachycardia
#13
Nikolaos Fragakis, Lydia Krexi, Panagiota Kyriakou, Melani Sotiriadou, Charalambos Lazaridis, Athanasios Karamanolis, Panagiotis Dalampyras, Stelios Tsakiroglou, Vassilios Skeberis, Dimitrios Tsalikakis, Vassilios Vassilikos
BACKGROUND: Radiofrequency (RF) ablation of the slow pathway (SP) in atrioventricular nodal reentry tachycardia (AVNRT) is occasionally complicated with atrioventricular block (AVB) often predicted by junctional beats (JB) with loss of ventriculo-atrial (VA) conduction. METHODS: We analysed retrospectively 153 patients undergoing ablation of SP for typical AVNRT. Patients were divided into two age groups: 127 ≤70 years and 26 > 70 years. We analysed the interval between the atrial electrogram in the His-bundle position and the distal ablation catheter [A(H)-A(RFd)] and the proximal coronary sinus catheter [A(RFd)-A(CS)] before RF applications with and without JB...
November 30, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29173611/a-novel-pacing-strategy-with-low-and-stable-output-pacing-the-left-bundle-branch-immediately-beyond-the-conduction-block
#14
Weijian Huang, Lan Su, Shengjie Wu, Lei Xu, Fangyi Xiao, Xiaohong Zhou, Kenneth A Ellenbogen
This report demonstrates the feasibility of pacing the left bundle branch (LBB) immediately beyond the conduction block to functionally restore the impaired His-Purkinje conduction system in a patient with heart failure and left bundle branch block (LBBB). The pacing required only a low pacing output (0.5 volts/0.5 ms) to correct the LBBB with accompanying right BBB on the electrocardiogram. Over 1-year of follow-up, the patient had a significant improvement in clinical outcome and echocardiographic measurements...
December 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29168622/mitral-valve-pressure-gradient-after-percutaneous-mitral-valve-repair-every-beat-counts
#15
Daniel Lavall, Bruno Scheller, Christian Werner, Axel Buob, Felix Mahfoud
A patient presented with symptoms of decompensated heart failure 2 months after percutaneous mitral valve (MV) repair. Echocardiography demonstrated impaired left ventricular function with elevated MV pressure gradients and pulmonary pressures during rapid atrial fibrillation. Heart rate control was achieved by implantation of a biventricular pacemaker with subsequent His-bundle ablation because atrial fibrillation was refractory to medical treatment. During biventricular pacing at different rates (50-110 b...
November 23, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29167624/unique-ventricular-tachycardia-originating-from-the-right-bundle-branch
#16
Hongliang Yang, Daoyuan Si, Yaliang Tong, Zhe An, Ping Yang, Yuquan He
Ventricular tachycardia (VT), a common arrhythmia, frequently originates from in the right ventricular outflow tract, left ventricular outflow tract, aortic sinus, and left ventricular papillary muscle but infrequently from the His-Purkinje system, whereas the VT stemming from the right bundle branch has rarely been reported. Here we reported a case with of VT originating from the right bundle branch which was subsequently successfully treated with radiofrequency ablation and demonstrated the electrocardiac features of VT using an electrophysiological examination...
November 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29165759/transient-receptor-potential-melastatin-4-cation-channel-in-pediatric-heart-block
#17
J Tian, X-J An, M-Y Fu
Progressive cardiac conduction disease (PCCD) is a common pediatric heart conduction disorder. It is an autosomal inheritance of rare mutations, which leads to familial cases of PCCD. In these cases, the His-Purkinje system's conductive capacity is progressively deranged, involving either right or left bundle branch block. Also, QRS complexes display widening is an important characteristic that culminates in complete AV block, syncope, and sudden death. Mutations in TRPM4 gene that encodes for transient receptor potential melastatin 4 have recently been reported to cause familial cases of PCCD and heart block...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29150300/permanent-his-bundle-pacing-to-replace-biventricular-pacing-for-cardiac-resynchronization-therapy
#18
Benjamin J Scherlag, Alexa Papaila
INTRODUCTION: Cardiac resynchronization therapy (CRT) or biventricular pacing (BIVP) has become a common procedure for the treatment of ventricular dyssynchrony in patients with heart failure, particularly in those with bundle branch block patterns (QRS durations >150ms) on the electrocardiogram (ECG). However, a large group of non-responders are made up of patients with dyssynchrony and QRS duration below 130ms. Recent studies have introduced permanent His bundle pacing as another method for achieving normalization of the QRS duration even in a majority of patients with right or left bundle branch block pattern on the ECG...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29113751/cardiomyopathy-induced-by-incessant-ventricular-tachycardia-originating-in-the-vicinity-of-the-his-bundle
#19
Sana Ouali, Manel Ben Halima, Selim Boudiche, Anissa Gharbi, Khedher Nadim, Kaouthar Hakim, Fatma Ouarda, Mohamed Sami Mourali
A 04-year-old boy was referred to our institution with severe, progressive heart failure of 4-months duration associated with a persistent wide QRS tachycardia with left bundle branch block and severe left ventricular dysfunction. Because of incessant wide QRS tachycardia refractory to antiarrhythmic drugs, he was referred for electrophysiological study. The ECG was suggestive of VT arising from the right ventricle near the His area. Electrophysiological study revealed that origin of tachycardia was septum of the right ventricle, near His bundle, however the procedure was not successful and an inadvertent complete atrioventricular conduction block occurred...
November 4, 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29107697/permanent-his-bundle-pacing-recommendations-from-a-multicenter-his-bundle-pacing-collaborative-working-group-for-standardization-of-definitions-implant-measurements-and-follow-up
#20
Pugazhendhi Vijayaraman, Gopi Dandamudi, Francesco Zanon, Parikshit S Sharma, Roderick Tung, Weijian Huang, Jayanthi Koneru, Hiroshi Tada, Kenneth A Ellenbogen, Daniel L Lustgarten
His bundle pacing (HBP) prevents ventricular dyssynchrony and its long-term consequences by preserving normal electrical activation of the ventricles. Since the original description of permanent HBP in 2000, the adoption of HBP has increased over the past several years. However, the reporting of procedural and clinical outcomes to date is not uniform. This article is a collaboration between several implanters with significant experience in HBP to establish a uniform set of definitions encompassing the different forms of HBP as well as define a standardized approach to gathering data end points to ensure consistency in reported outcomes...
October 28, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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