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https://www.readbyqxmd.com/read/29782689/common-and-distinctive-electrocardiographic-characteristics-and-effective-catheter-ablation-of-idiopathic-ventricular-arrhythmias-originating-from-different-areas-of-ventricular-septum-adjacent-to-atrioventricular-annulus
#1
Su-Qin Zhang, Cheng Zheng, Yue-Chun Li, Kang-Ting Ji, Ri-Peng Yin, Jia-Feng Lin, Jia Li
OBJECTIVE: To investigate electrocardiographic (ECG) characteristics and radiofrequency catheter ablation (RFCA) efficacy for premature ventricular complexes (PVCs) and idiopathic ventricular tachycardias (IVTs) originating from ventricular septum areas adjacent to atrioventricular annulus (VS-AVA). METHODS: Among 1505 consecutive PVCs/IVTs cases, 106 (7.04%) were confirmed as origin of VS-AVA guided by both fluoroscopy and three-dimensional mapping system during RFCA...
May 21, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29781518/an-interesting-case-of-wide-qrs-tachycardia-with-right-bundle-branch-block-morphology-what-is-the-mechanism
#2
Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Hiren Kevadiya, Ajitkumar Valaparambil
A 30 year old gentleman with no structural heart disease has been evaluated for paroxysmal palpitation with documented regular wide QRS tachycardia that has not responded to IV adenosine. Surface electrocardiogram has not shown any pre-excitation. He has been taken for an EP study after informed consent. Diagnostic catheters were placed at coronary sinus (CS), His bundle region and right ventricle (RV). During catheter manipulation a regular wide QRS tachycardia with right bundle branch block morphology (RBBB) with a tachycardia cycle length (TCL) of 400 ms and normal QRS axis similar to the clinical tachycardia got induced (Fig:1)...
May 21, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29773160/his-bundle-pacing-the-holy-grail-of-pacing
#3
EDITORIAL
Kenneth A Ellenbogen, Santosh K Padala
No abstract text is available yet for this article.
May 22, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29759837/clinical-features-and-sites-of-ablation-for-patients-with-incessant-supraventricular-tachycardia-from-concealed-nodofascicular-and-nodoventricular-tachycardias
#4
Frederick T Han, Eric M Riles, Nitish Badhwar, Melvin M Scheinman
OBJECTIVES: This study sought to describe the clinical features and sites of successful ablation for incessant nodofascicular (NF) and nodoventricular (NV) tachycardias. BACKGROUND: Incessant supraventricular tachycardias have been associated with tachycardia-induced cardiomyopathies and have been previously attributed to permanent junctional reciprocating tachycardias, atrial tachycardias, and atrioventricular nodal re-entrant tachycardias. Incessant concealed NF and NV tachycardias have not been described previously...
December 26, 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759615/enhancing-response-in-the-cardiac-resynchronization-therapy-patient-the-3b-perspective-bench-bits-and-bedside
#5
REVIEW
Angelo Auricchio, Frits W Prinzen
Cardiac resynchronization therapy (CRT) is an established nonpharmacological treatment for patients with heart failure (HF), reduced left ventricular (LV) ejection fraction, and a wide QRS complex. Although the therapy was developed 30 years ago and approved by the Food and Drug Administration in 2001, attempts to improve it have never stopped. Such improvements have been facilitated by combining knowledge from bench (basic science), bits (computer modeling), and bedside (clinical studies); these issues are addressed in the present review...
November 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29758403/progression-of-intra-hisian-atrioventricular-block-will-this-presage-a-renaissance-of-his-bundle-studies
#6
EDITORIAL
Melvin M Scheinman
No abstract text is available yet for this article.
May 11, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29709577/endocardial-ablation-of-ventricular-ectopic-beats-arising-from-the-basal-infero-septal-process-of-the-left-ventricle
#7
Anthony Li, Zia Zuberi, Jason S Bradfield, John K Zarif, David E Ward, Robert H Anderson, Kalyanam Shivkumar, Magdi M Saba
BACKGROUND: Idiopathic VE shows predilection to sites within the left ventricular base such as the outflow tract/aortic sinuses, LV summit and adjacent to the aorto-mitral continuity. We characterize VE arising from the inferior septum of the LV base that were successfully managed by LV endocardial ablation from the infero-septal recess of the LV. OBJECTIVES: To determine the incidence, electrocardiographic, electrophysiological findings and anatomical features associated with ventricular ectopy (VE) arising from the basal infero-septal process of the left ventricle (ISP-LV) ablated using an LV endocardial approach via the infero-septal recess of the left ventricle...
April 27, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29701822/permanent-his-bundle-pacing-a-systematic-literature-review-and-meta-analysis
#8
Francesco Zanon, Kenneth A Ellenbogen, Gopi Dandamudi, Parikshit S Sharma, Weijian Huang, Daniel L Lustgarten, Roderick Tung, Hiroshi Tada, Jayanthi N Koneru, Tracy Bergemann, Dedra H Fagan, John Harrison Hudnall, Pugazhendhi Vijayaraman
Aims: Permanent cardiac pacing of the His-bundle restores and retains normal electrical activation of the ventricles. Data on His-bundle pacing (HBP) are largely limited to small single-centre reports, and clinical benefits and risks have not been systematically examined. We sought to systematically examine published studies of patients undergoing permanent HBP and quantify the benefits and risks of the therapy. Methods and results: PubMed, Embase, and Cochrane Library were searched for full-text articles on permanent HBP...
April 26, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29678778/clinical-and-electrophysiologic-characteristics-of-patients-with-paroxysmal-intra-his-block-with-narrow-qrs-complexes
#9
Loheetha Ragupathi, Drew Johnson, Arnold Greenspon, Daniel Frisch, Reginald T Ho, Behzad B Pavri
BACKGROUND: Atrioventricular block (AVB) is usually due to infra-nodal disease and associated with a wide QRS complex; such patients often progress to complete AV block and pacemaker dependency. Uncommonly, infra-nodal AVB can occur within the His bundle with a narrow QRS complex. OBJECTIVE: To define clinical/echocardiographic characteristics of patients with AV block within the His bundle and report on progression to pacemaker dependency. METHODS: We retrospectively identified patients with narrow QRS complexes and documented intra-His delay or block on electrophysiologic study (Group A), or with ECG documented Mobitz II AVB/paroxysmal AVB (Group B)...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29622459/upgrade-to-his-bundle-pacing-in-pacing-dependent-patients-referred-for-pulse-generator-change-feasibility-and-intermediate-term-follow-up
#10
Yang Ye, Zuwen Zhang, Xia Sheng, Bei Wang, Shiquan Chen, Yiwen Pan, Jingliang Lan, Yaxun Sun, Yi Luan, Chenyang Jiang, Guosheng Fu
BACKGROUND: Right ventricular pacing (RVP) is associated with an increased incidence of heart failure and may impair cardiac function. Permanent His bundle pacing (HBP) has the potential to physiologically preserve and prevent cardiac dysfunction. This study was to evaluate the feasibility and intermediate follow-up results of upgrade to HBP implantation in patients referred for pulse generator change with long term RVP. METHODS: Twelve of 14 pacing dependent patients who were referred for pulse generator exchange underwent upgrade into HBP successfully in our center...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29622418/permanent-his-bundle-pacing-a-physiological-alternative-to-conventional-right-ventricular-pacing-or-just-a-futile-artifice
#11
EDITORIAL
Giuseppe Ricciardi, Luca Checchi
No abstract text is available yet for this article.
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29622376/mahaim-fiber-mediated-tachycardia
#12
Gustavo Lima da Silva, Nuno Cortez-Dias, Ana Bernardes, João Sousa
We present the case of a previously healthy 42-year-old man who attended the emergency department due to a sudden onset of rapid and regular palpitations. The ECG showed 190 bpm, wide QRS with left bundle branch block tachycardia. He was started on amiodarone with progression to 230 bpm, wide QRS tachycardia with multiple morphologies, followed by spontaneous conversion to sinus rhythm, normal PR interval and rS pattern in LIII. The echocardiogram was negative for structural heart disease. The electrophysiological study demonstrated the presence of an accessory pathway with anterograde decremental conduction and no retrograde conduction...
April 2, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29618529/de-novo-synthetic-biliprotein-design-assembly-and-excitation-energy-transfer
#13
Joshua A Mancini, Molly Sheehan, Goutham Kodali, Brian Y Chow, Donald A Bryant, P Leslie Dutton, Christopher C Moser
Bilins are linear tetrapyrrole chromophores with a wide range of visible and near-visible light absorption and emission properties. These properties are tuned upon binding to natural proteins and exploited in photosynthetic light-harvesting and non-photosynthetic light-sensitive signalling. These pigmented proteins are now being manipulated to develop fluorescent experimental tools. To engineer the optical properties of bound bilins for specific applications more flexibly, we have used first principles of protein folding to design novel, stable and highly adaptable bilin-binding four-α-helix bundle protein frames, called maquettes, and explored the minimal requirements underlying covalent bilin ligation and conformational restriction responsible for the strong and variable absorption, fluorescence and excitation energy transfer of these proteins...
April 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29608497/his-bundle-pacing-hemodynamics-and-clinical-outcomes
#14
Brijesh Patel, Jalaj Garg, Rahul Chaudhary, Naveen Sablani, Rahul Gupta, Mahek Shah, Talha Nazir, Babak Bozorgnia, Andrea Natale
From 1993 to 2009, nearly 2.9 million pacemakers were implanted in the United States; the majority of which were dual chamber pacemakers. One of the major physiologic advantages of dual chamber pacing over single chamber ventricular pacing is atrioventricular synchrony, which prevents the pacemaker syndrome. However, patients who are pacemaker dependent or use right ventricle (RV) apical pacing more than 40% of the time are at a risk of developing heart failure from electromechanical dyssynchrony. Studies have also shown that RV pacing results in non-physiological activation of the left ventricle, leading to adverse clinical outcomes...
March 30, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29562793/wolff-parkinson-white-syndrome-and-noncompaction-in-leber-s-hereditary-optic-neuropathy-due-to-the-variant-m-3460g-a
#15
Josef Finsterer, Claudia Stollberger, Edmund Gatterer
This report describes a 66-year-old Caucasian male who acutely developed severe, bilateral impairment of visual acuity at 24 years of age. Leber's hereditary optic neuropathy (LHON) was suspected but the diagnosis was not genetically confirmed until the age of 49 years when the primary LHON mutation m.3460G>A was detected. Since onset, visual acuity had slightly improved. The family history was positive for LHON (brother, two sisters of mother, female cousin) and genetically confirmed in his brother and one aunt...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29551122/glucose-monitoring-dermopathy
#16
Warren R Heymann
A 75-year-old man had been monitoring his glucose using a blood glucose monitoring system at the same body site for at least 20 years (>7300 needlesticks). The asymptomatic skin lesion had been present for many years. He used the same site because it hurt less than the fingers and bled well. His medical history was remarkable for diabetes mellitus, hypertension, coronary artery disease, and a pacemaker. His medications included glipizide, metformin, carvedilol, furosemide, lisinopril, amlodipine, clopidogrel, and aspirin...
2018: Skinmed
https://www.readbyqxmd.com/read/29550833/a-case-of-lown-ganong-levine-syndrome-due-to-an-accessory-pathway-of-james-fibers-or-enhanced-atrioventricular-nodal-conduction-eavnc
#17
Juanita Hunter, Emmanouil Tsounias, John Cogan, Ming-Lon Young
BACKGROUND Lown-Ganong-Levine syndrome, includes a short PR interval, normal QRS complex, and paroxysmal tachycardia. The pathophysiology of this syndrome includes an accessory pathway connecting the atria and the atrioventricular (AV) node (James fiber), or between the atria and the His bundle (Brechenmacher fiber). Similar features are seen in enhanced atrioventricular nodal conduction (EAVNC), with the underlying pathophysiology due to a fast pathway to the AV node, and with the diagnosis requiring specific electrophysiologic criteria...
March 18, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29535066/clinical-outcomes-of-his-bundle-pacing-compared-to-right-ventricular-pacing
#18
Mohamed Abdelrahman, Faiz A Subzposh, Dominik Beer, Brendan Durr, Angela Naperkowski, Haiyan Sun, Jess W Oren, Gopi Dandamudi, Pugazhendhi Vijayaraman
BACKGROUND: Right ventricular pacing (RVP) is associated with heart failure and increased mortality. His bundle pacing (HBP) is a physiological alternative to RVP. OBJECTIVES: This study sought to evaluate clinical outcomes of HBP compared to RVP. METHODS: All patients requiring initial pacemaker implantation between October 1, 2013, and December 31, 2016, were included in the study. Permanent HBP was attempted in consecutive patients at 1 hospital and RVP at a sister hospital...
May 22, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29534954/surgery-of-hypertrophic-obstructive-cardiomyopathy-in-patients-with-severe-hypertrophy-myocardial-fibrosis-and-ventricular-tachycardia
#19
Konstantin V Borisov
BACKGROUND: In patients with hypertrophic obstructive cardiomyopathy myocardial fibrosis is an independent predictor of adverse outcome. A new technique of HOCM surgical correction in patients with severe hypertrophy and septal myocardial fibrosis has been proposed. METHODS: The excision of the asymmetrical hypertrophied area of the interventricular septum causing obstruction was performed from the conal part of the right ventricle corresponding to the zone of obstruction of the left ventricle (LV)...
March 10, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29525386/cardiac-resynchronization-therapy-with-his-bundle-pacing-as-a-method-of-treatment-of-chronic-heart-failure-in-patients-with-permanent-atrial-fibrillation-and-left-bundle-branch-block
#20
Krzysztof Boczar, Agnieszka Sławuta, Andrzej Ząbek, Maciej Dębski, Jacek Gajek, Jacek Lelakowski, Barbara Małecka
CRT is a therapeutic option for patients with heart failure, sinus rhythm, prolonged QRS complex duration and reduced ejection fraction. We present a case of 71-year-old woman with dilated cardiomyopathy, NYHA functional class III and AF. We implanted CRT combined with direct His-bundle pacing. The indication for such a therapy was a left bundle branch block with a QRS complex of 178ms and a left ventricular EF of 15%, left ventricular end-diastolic diameter (LVEDD) of 75mm. After 8months of follow-up the LVEDD was 60mm with EF 35-40%...
March 2, 2018: Journal of Electrocardiology
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