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https://www.readbyqxmd.com/read/27904615/the-effect-of-flaxseed-powder-on-insulin-resistance-indices-and-blood-pressure-in-prediabetic-individuals-a-randomized-controlled-clinical-trial
#1
Afrooz Javidi, Hassan Mozaffari-Khosravi, Azadeh Nadjarzadeh, Ali Dehghani, Mohammad Hassan Eftekhari
BACKGROUND: Designing the effective and early interventions can prevent progression of prediabetes to diabetes. Few studies have shown the effect of flaxseed on glycemic control. This study aimed to assess the effect of flaxseed powder on insulin resistance (IR) indices and blood pressure in prediabetic individuals. MATERIALS AND METHODS: In a randomized clinical trial, 99 prediabetic individuals were randomly divided into three groups: two groups received 40 g (FG40) and 20 g (FG20) flaxseed powder daily for 12 weeks and the third group was the control (CG)...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27902927/antidiabetic-activity-of-ganoderma-lucidum-polysaccharides-f31-down-regulated-hepatic-glucose-regulatory-enzymes-in-diabetic-mice
#2
Chun Xiao, Qingping Wu, Jumei Zhang, Yizhen Xie, Wen Cai, Jianbin Tan
ETHNOPHARMACOLOGICAL RELEVANCE: Ganoderma lucidum (Lin Zhi) has been used to treat diabetes in Chinese folk for centuries. Our laboratory previously demonstrated that Ganoderma lucidum polysaccharides (GLPs) had hypoglycemic effects in diabetic mice. Our aim was to identify the main bioactives in GLPs and corresponding mechanism of action. MATERIALS AND METHODS: Four polysaccharide-enriched fraction were isolated from GLPs and the antidiabetic activities were evaluated by type 2 diabetic mice...
November 27, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27842826/pectin-and-enzyme-complex-modified-fish-scales-gelatin-rheological-behavior-gel-properties-and-nanostructure
#3
Tao Huang, Zong-Cai Tu, Hui Wang, Xinchen Shangguan, Lu Zhang, Nan-Hai Zhang, Nidhi Bansal
The rheological behavior, gel properties and nanostructure of complex modified fish scales gelatin (FSG) by pectin and microbial transglutaminase (MTGase) were investigated. The findings suggested that MTGase and pectin have positive effect on the gelation point, melting point, apparent viscosity and gel properties of FSG. The highest values of gel strength and melting temperature could be observed at 0.8% (w/v) pectin. Nevertheless, at highest pectin concentration (1.6% w/v), the gel strength and melting temperature of complex modified gelatin gels decreased...
January 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27757369/human-health-risks-from-heavy-metals-in-fish-of-buriganga-river-bangladesh
#4
Md Kawser Ahmed, Mohammad Abdul Baki, Goutam Kumar Kundu, Md Saiful Islam, Md Monirul Islam, Md Muzammel Hossain
Heavy metals are known to cause deleterious effects on human health through food chain. Human health risks were evaluated from consumption of heavy metal contaminated fish from Buriganga River in Bangladesh. Whole body of five fish species (Puntius ticto, Puntius sophore, Puntius chola, Labeo rohita and Glossogobius giuris) were analyzed which contained various concentrations of Cd, As, Pb, Cr, Ni, Zn, Se, Cu, Mo, Mn, Sb, Ba, V and Ag. Concentrations of Mn, Zn, Se and Pb in all fish species were above the Food Safety Guideline (FSG) by WHO/FAO...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27756478/effect-on-fasting-serum-glucose-levels-of-adding-ezetimibe-to-statins-in-patients-with-nondiabetic-hypercholesterolemia
#5
Peter P Toth, Alberico L Catapano, Michel Farnier, Joanne Foody, Joanne E Tomassini, Erin Jensen, Adam B Polis, Mary E Hanson, Thomas A Musliner, Andrew M Tershakovec
Statin therapy is associated with a slightly increased risk of developing diabetes mellitus and insulin resistance in patients without diabetes. Ezetimibe combined with statins may be considered for high-risk patients who do not achieve optimal low-density lipoprotein cholesterol lowering on statin monotherapy or who are statin intolerant. Changes in fasting serum glucose (FSG) levels during ezetimibe, ezetimibe/statin, and statin treatments were assessed using data pooled from clinical trials in hypercholesterolemic and heterozygous familial hypercholesterolemic patients, who were or were not receiving statin therapy...
December 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27716036/identification-of-large-disjoint-motifs-in-biological-networks
#6
Rasha Elhesha, Tamer Kahveci
BACKGROUND: Biological networks provide great potential to understand how cells function. Network motifs, frequent topological patterns, are key structures through which biological networks operate. Finding motifs in biological networks remains to be computationally challenging task as the size of the motif and the underlying network grow. Often, different copies of a given motif topology in a network share nodes or edges. Counting such overlapping copies introduces significant problems in motif identification...
October 6, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/27682405/facile-synthesis-of-a-luminescent-material-pan-sio2-n-having-a-simultaneous-binding-capacity-of-high-and-low-oxidation-states-homo-and-lumo-quantum-mechanical-descriptor-of-break-through-capacity
#7
Mousumi Chatterjee, Bhavya Srivastava, Milan K Barman, Bhabatosh Mandal
A time-cost effective, chemically stable mesoporous resin (FSG-PAN), simultaneous binder of two different metal centers (both high (Cd(II)) and low (Tl(I)) oxidation states), has been synthesized by immobilizing azo-dye (1-(2-pyridylazo)-2-napthol: PAN) on functionalized silica gel (FSG). Its corresponding synthesized nano material possesses good luminescent properties, and has been utilized in fluoride sensing at trace levels (1.8 × 10(-6) - 7.2 × 10(-6) M). The composition ({Si[OSi]p=4[H2O]x=0.81}12[-Si(CH3)2-NH-C6H4-N=N-PAN]4...
2016: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/27632197/alcohol-intake-and-serum-glucose-levels-from-the-perspective-of-a-mendelian-randomization-design-the-kcps-ii-biobank
#8
Yon Ho Jee, Sun Ju Lee, Keum Ji Jung, Sun Ha Jee
BACKGROUND: Previous studies have suggested that alcohol intake is associated with increased fasting serum glucose (FSG), but the nature of the relationship remains unknown. We used Mendelian randomization analysis to assess the causal effect of alcohol intake on FSG in a middle-aged Korean population. METHODS: Clinical data including FSG and alcohol intake were collected from 156,386 Koreans aged 20 years or older who took part in the Korean Cancer Prevention Study-II (KCPS-II) Biobank Cohort...
2016: PloS One
https://www.readbyqxmd.com/read/27630113/food-service-guideline-policies-on-state-government-controlled-properties
#9
Hatidza Zaganjor, Katherine Bishop Kendrick, Amy Lowry Warnock, Stephen Onufrak, Laurie P Whitsel, Julie Ralston Aoki, Joel Kimmons
PURPOSE: Food service guideline (FSG) policies can impact millions of daily meals sold or provided to government employees, patrons, and institutionalized persons. This study describes a classification tool to assess FSG policy attributes and uses it to rate FSG policies. DESIGN: Quantitative content analysis. SETTING: State government facilities in the United States. PARTICIPANTS: Participants were from 50 states and District of Columbia in the United States...
September 13, 2016: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/27475283/glucose-homeostasis-insulin-resistance-and-inflammatory-biomarkers-in-patients-with-non-alcoholic-fatty-liver-disease-beneficial-effects-of-supplementation-with-microalgae-chlorella-vulgaris-a-double-blind-placebo-controlled-randomized-clinical-trial
#10
Mehrangiz Ebrahimi-Mameghani, Zahra Sadeghi, Mahdieh Abbasalizad Farhangi, Elnaz Vaghef-Mehrabany, Soodabeh Aliashrafi
BACKGROUND: Chlorella vulgaris (C. vulgaris) is reported to improve dyslipidemia and hypertension; however, its effect on inflammatory biomarkers and insulin resistance has not been noticed thus far. Non-alcoholic fatty liver disease (NAFLD) as a hepatic symptom of metabolic syndrome is strongly associated with insulin resistance and inflammation. AIM OF THE STUDY: In the current interventional trial, we aimed to study the effects of C. vulgaris supplementation on glucose homeostasis, insulin resistance and inflammatory biomarkers in patients with NAFLD...
July 19, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27426415/malnutrition-risk-predicts-recovery-of-full-oral-intake-among-older-adult-stroke-patients-undergoing-enteral-nutrition-secondary-analysis-of-a-multicentre-survey-the-apple-study
#11
Shinta Nishioka, Takatsugu Okamoto, Masako Takayama, Maki Urushihara, Misuzu Watanabe, Yumiko Kiriya, Keiko Shintani, Hiromi Nakagomi, Noriko Kageyama
BACKGROUND & AIMS: Whether malnutrition risk correlates with recovery of swallowing function of convalescent stroke patients is unknown. This study was conducted to clarify whether malnutrition risks predict achievement of full oral intake in convalescent stroke patients undergoing enteral nutrition. METHODS: We conducted a secondary analysis of 466 convalescent stroke patients, aged 65 years or over, who were undergoing enteral nutrition. Patients were extracted from the "Algorithm for Post-stroke Patients to improve oral intake Level; APPLE" study database compiled at the Kaifukuki (convalescent) rehabilitation wards...
July 6, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27379242/hemodynamic-functions-of-fenestrated-stent-graft-under-resting-hypertension-and-exercise-conditions
#12
Harkamaljot Singh Kandail, Mohamad Hamady, Xiao Yun Xu
The aim of this study was to assess the hemodynamic performance of a patient-specific fenestrated stent graft (FSG) under different physiological conditions, including normal resting, hypertension, and hypertension with moderate lower limb exercise. A patient-specific FSG model was constructed from computed tomography images and was discretized into a fine unstructured mesh comprising tetrahedral and prism elements. Blood flow was simulated using Navier-Stokes equations, and physiologically realistic boundary conditions were utilized to yield clinically relevant results...
2016: Frontiers in Surgery
https://www.readbyqxmd.com/read/27339447/genetic-and-environmental-influences-on-the-associations-between-change-in-kidney-function-and-changes-in-cardiometabolic-factors-in-koreans
#13
Yun-Mi Song, Joohon Sung, Kayoung Lee
BACKGROUND: This study aimed to evaluate genetic and environmental relations between change in estimated glomerular filtration rate (eGFR) and changes in cardiometabolic factors. METHODS: In 1772 Korean adults without diabetes and chronic kidney disease at baseline, changes in eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation, blood pressure (BP), fasting serum glucose (FSG), insulin, homeostasis model assessment of insulin resistance index (HOMA-IR), hemoglobin A1c, triglycerides, high and low density lipoprotein cholesterol (HDL and LDL), uric acid, white blood cell (WBC) count, and body mass index (BMI) were calculated as follows: (value at follow-up - value at baseline) × 100/[value at baseline × follow-up interval (years)]...
June 23, 2016: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/27265893/baseline-factors-associated-with-glycaemic-response-to-treatment-with-once-weekly-dulaglutide-in-patients-with-type-2-diabetes
#14
Carol Wysham, Bruno Guerci, David D'Alessio, Nan Jia, Fady T Botros
Dulaglutide glycaemic efficacy has been demonstrated in the AWARD clinical trial program. The objective of this analysis was to determine the major baseline factors associated with the reduction in HbA1c in response to dulaglutide. Baseline covariates from dulaglutide patients in 6 phase 3 studies (n = 2806) were analysed using gradient boosting method to assess their relative influence to the change in HbA1c at 26 weeks of treatment. Influential variables (relative influence >5%) were further evaluated in univariate and multivariable modeling...
June 6, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27225213/effect-of-a-flared-renal-stent-on-the-performance-of-fenestrated-stent-grafts-at-rest-and-exercise-conditions
#15
Harkamaljot Kandail, Mohamad Hamady, Xiao Yun Xu
PURPOSE: To quantify the hemodynamic impact of a flared renal stent on the performance of fenestrated stent-grafts (FSGs) by analyzing flow patterns and wall shear stress-derived parameters in flared and nonflared FSGs in different physiologic scenarios. METHODS: Hypothetical models of FSGs were created with and without flaring of the proximal portion of the renal stent. Flared FSGs with different dilation angles and protrusion lengths were examined, as well as a nonplanar flared FSG to account for lumbar curvature...
October 2016: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/27087273/food-intake-patterns-are-associated-with-the-risk-of-impaired-glucose-and-insulin-homeostasis-a-prospective-approach-in-the-tehran-lipid-and-glucose-study
#16
Tayebeh Doostvandi, Zahra Bahadoran, Hassan Mozaffari-Khosravi, Parvin Mirmiran, Fereidoun Azizi
OBJECTIVE: To investigate the association of major dietary patterns with the risk of impaired glucose and insulin homeostasis during a 3-year follow-up. DESIGN: Fasting serum insulin (FSI), fasting (FSG) and 2 h serum glucose (2h-SG) were measured at baseline and again after 3 years. Dietary intakes were evaluated using a validated 168-item semi-quantitative FFQ and major dietary patterns were obtained using principal component analysis. Logistic regression models were used to estimate the occurrence of impaired fasting glucose (IFG), impaired glucose tolerance (IGT), pre-diabetes (IGT/IFG), β-cell dysfunction and hyperinsulinaemia across tertiles of dietary patterns, with adjustment for potential confounding variables...
September 2016: Public Health Nutrition
https://www.readbyqxmd.com/read/26942038/biological-evaluation-of-pupalia-lappacea-for-antidiabetic-antiadipogenic-and-hypolipidemic-activity-both-in-vitro-and-in-vivo
#17
Vivek Kumar, Parag Jain, Kalpana Rathore, Zabeer Ahmed
Objective. The present study assesses the effect of Pupalia lappacea (L.) Juss. (Amaranthaceae) (PL) leaves ethanolic extract on adipocytes, blood glucose level, and lipid level in streptozotocin (STZ) induced diabetic rats. Materials and Methods. Male Albino rats were rendered diabetic by a single moderately sized dose of STZ (45 mg/kg, intraperitoneally) at once before starting the treatment. Animals were divided into five groups: normoglycemic control, diabetic control, reference group (glibenclamide, 5...
2016: Scientifica
https://www.readbyqxmd.com/read/26940900/parkinsonia-aculeata-caesalpineaceae-improves-high-fat-diet-induced-insulin-resistance-in-mice-through-the-enhancement-of-insulin-signaling-and-mitochondrial-biogenesis
#18
Tiago Gomes Araújo, Alexandre Gabarra de Oliveira, Juliana Falcato Vecina, Rodrigo Miguel Marin, Eryvelton Souza Franco, Mario J Abdalla Saad, Maria Bernadete de Sousa Maia
ETHNOPHARMACOLOGICAL RELEVANCE: The search for natural agents that minimize obesity-associated disorders is receiving special attention. Parkinsonia aculeata L. (Caesalpineaceae) has long been used in Brazil as a hypoglycaemic herbal medicine, without any scientific basis. AIMS OF THE STUDY: In this context, we aimed to use molecular and physiological methods to study the effect of a hydroethanolic extract partitioned with ethyl acetate from the aerial parts of Parkinsonia aculeata (HEPa/EtOAc) on insulin resistance in a mouse model of diet-induced obesity (DIO)...
May 13, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26896921/combined-cation-exchange-and-solid-phase-extraction-for-the-selective-separation-and-preconcentration-of-zinc-copper-cadmium-mercury-and-cobalt-among-others-using-azo-dye-functionalized-resin
#19
Mousumi Chatterjee, Bhavya Srivastava, Milan K Barman, Bhabatosh Mandal
A facile synthesis of an ion exchange material (FSG-PAN) has been achieved by functionalizing silica gel with an azo-dye. Its composition and structure are well assessed by systematic analysis. Extractor possesses high BET surface area (617.794m(2)g(-1)), exchange capacity and break-through capacity (BTC) (Q0 Zn(II): 225; Cd(II): 918; Hg(II): 384, Cu(II): 269 and Co(II): 388μMg(-1)). The sorption process was endothermic (+ΔH), entropy-gaining (+ΔS) and spontaneous (-ΔG) in nature. Preconcentration factor has been optimized at 172(Zn(II)); 157...
April 1, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/26872721/the-effect-of-enriched-chicory-inulin-on-liver-enzymes-calcium-homeostasis-and-hematological-parameters-in-patients-with-type-2-diabetes-mellitus-a-randomized-placebo-controlled-trial
#20
Mahdieh Abbasalizad Farhangi, Ahmad Zare Javid, Parvin Dehghan
BACKGROUNDS AND AIMS: Type 2 diabetic mellitus (T2DM) as one of the main causes of morbidity and mortality is associated with immune system disturbances and metabolic abnormalities. In the current study we aimed to evaluate the effects of enriched chicory inulin supplementation on liver enzymes, serum calcium and phosphorous concentrations and hematological parameters in patients with T2DM. METHODS: Forty-six diabetic females patients were randomly allocated into intervention (n=27) and control (n=22) groups...
August 2016: Primary Care Diabetes
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