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https://www.readbyqxmd.com/read/28334939/association-between-tau-deposition-and-antecedent-amyloid-%C3%AE-accumulation-rates-in-normal-and-early-symptomatic-individuals
#1
Duygu Tosun, Susan Landau, Paul S Aisen, Ronald C Petersen, Mark Mintun, William Jagust, Michael W Weiner
A long-term goal of our field is to determine the sequence of pathological events, which ultimately lead to cognitive decline and dementia. In this study, we first assessed the patterns of brain tau tangle accumulation (measured with the positron emission tomography tracer 18F-AV-1451) associated with well-established Alzheimer's disease factors in a cohort including cognitively healthy elderly individuals and individuals at early symptomatic stages of Alzheimer's disease. We then explored highly associated patterns of greater 18F-AV-1451 binding and increased annualized change in cortical amyloid-β plaques measured as florbetapir positron emission tomography binding antecedent to 18F-AV-1451 positron emission tomography scans, and to what extent these multimodal pattern associations explained the variance in cognitive performance and clinical outcome measures, independently and jointly...
March 17, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28334548/waist-circumference-is-associated-with-liver-fat-in-black-and-white-adolescents
#2
SoJung Lee, Jennifer L Kuk, Chris Boesch, Silva Arslanian
We examined whether waist circumference (WC) is associated with liver fat in black and white adolescents. Liver fat was measured using a 3T proton magnetic resonance spectroscopy (1H-MRS) in 152 overweight/obese adolescents (94 black and 58 white, BMI >85th percentile, 12-18 yrs) without liver diseases or diabetes. WC was measured at the last rib. Total and visceral adipose tissue (VAT) were measured by DXA and MRI, respectively. The proportion of fatty liver (defined as liver fat >5.0% by 1H-MRS) was lower (P<0...
March 23, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28324871/herd-specific-random-regression-carcass-profiles-for-beef-cattle-after-adjustment-for-animal-genetic-merit
#3
Tanya M Englishby, Kirsty L Moore, Donagh P Berry, Mike P Coffey, Georgios Banos
Abattoir data are an important source of information for the genetic evaluation of carcass traits, but also for on-farm management purposes. The present study aimed to quantify the contribution of herd environment to beef carcass characteristics (weight, conformation score and fat score) with particular emphasis on generating finishing herd-specific profiles for these traits across different ages at slaughter. Abattoir records from 46,115 heifers and 78,790 steers aged between 360 and 900days, and from 22,971 young bulls aged between 360 and 720days, were analysed...
March 7, 2017: Meat Science
https://www.readbyqxmd.com/read/28323829/potentially-modifiable-lifestyle-factors-cognitive-reserve-and-cognitive-function-in-later-life-a-cross-sectional-study
#4
Linda Clare, Yu-Tzu Wu, Julia C Teale, Catherine MacLeod, Fiona Matthews, Carol Brayne, Bob Woods
BACKGROUND: Potentially modifiable lifestyle factors may influence cognitive health in later life and offer potential to reduce the risk of cognitive decline and dementia. The concept of cognitive reserve has been proposed as a mechanism to explain individual differences in rates of cognitive decline, but its potential role as a mediating pathway has seldom been explored using data from large epidemiological studies. We explored the mediating effect of cognitive reserve on the cross-sectional association between lifestyle factors and cognitive function in later life using data from a population-based cohort of healthy older people...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28322653/underlying-beliefs-associated-with-college-student-consumption-of-energy-beverages
#5
Janet Thorlton, William B Collins
College students are heavy consumers of energy beverages, yet further study is needed to better understand determinants of use. The purpose of this cross-sectional study ( N = 283) was to identify beliefs explaining unsafe consumption practices. A principal components analysis revealed three eigenvalues >1 explaining approximately 55% of the variance (health and appearance, performance and fatigue, and recreation and alcohol). Multiple regression analysis explained 75% of the variance for intent to consume...
January 1, 2017: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28321189/plasma-tau-levels-in-cognitively-normal-middle-aged-and-older-adults
#6
Ming-Jang Chiu, Ling-Yun Fan, Ta-Fu Chen, Ya-Fang Chen, Jen-Jei Chieh, Herng-Er Horng
Using an ultra-sensitive technique, an immunomagnetic reduction assay, the plasma tau level can be measured to a limit of quantification of pg/ml. In total 126 cognitively normal middle-aged and older adults (45-95 years old) were recruited. The plasma tau levels were significantly higher in the older group (aged 65-95 years) 18.14 ± 7.33 pg/ml than those in the middle-aged group (aged 45-64 years) 14.35 ± 6.49 pg/ml when controlled gender and ApoEε4 carrier status (F = 3.102, P = 0.029). The ApoEε4 carriers had higher plasma tau levels than the non-carriers when controlled age and gender (F = 6...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28320030/changes-in-regulatory-t-cell-levels-in-acute-cerebral-ischemia
#7
Xuerui Pang, Weidong Qian
Background Acute stroke causes intense and significant changes in the immune system as well as in the number and the ratio of various immune cells. Material and Methods Several large-scale studies have shown that ischemic stroke leaves the human body in a state of immunodepression. The regulatory T (Treg) cells may be strongly associated with a change of immune status. In this trial, we collected venous blood from a cohort of patients who were diagnosed with acute ischemic stroke within the last 24 hours (n = 139)...
March 20, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28318919/the-current-preferred-female-lip-ratio
#8
Paul I Heidekrueger, Sabrina Juran, Caroline Szpalski, Lorenz Larcher, Reuben Ng, P Niclas Broer
BACKGROUND: Perception of beauty is influenced by the individual's demographic background and characteristics. However, objective measurements and ratios remain the foundation for aesthetic evaluations. This study aimed to elucidate if there exists a universally applicable ideal upper to lower lip ratio. METHODS: An interactive online survey was designed. Modifiable ranges of lip ratios were achieved via digital alteration, enabling participants to change the ratio of a single female model's lips...
February 12, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28318754/differences-between-men-and-women-in-substance-use-the-role-of-educational-level-and-employment-status
#9
Ester Teixidó-Compañó, Albert Espelt, Luis Sordo, María J Bravo, Ana Sarasa-Renedo, B Iciar Indave, Marina Bosque-Prous, M Teresa Brugal
OBJECTIVE: To determine differences between men and women in hazardous drinking, heavy cannabis use and hypnosedative use according to educational level and employment status in the economically active population in Spain. METHOD: Cross-sectional study with data from 2013 Spanish Household Survey on Alcohol and Drugs on individuals aged 25-64 [n=14,113 (women=6,171; men=7,942)]. Dependent variables were hazardous drinking, heavy cannabis use and hypnosedative consumption; the main independent variables were educational level and employment situation...
March 15, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28318319/medical-student-perceptions-of-the-learning-environment-in-medical-school-change-as-students-transition-to-clinical-training-in-undergraduate-medical-school
#10
Lisette Dunham, Michael Dekhtyar, Gregory Gruener, Eileen CichoskiKelly, Jennifer Deitz, Donna Elliott, Margaret L Stuber, Susan E Skochelak
Phenomenon: The learning environment is the physical, social, and psychological context in which a student learns. A supportive learning environment contributes to student well-being and enhances student empathy, professionalism, and academic success, whereas an unsupportive learning environment may lead to burnout, exhaustion, and cynicism. Student perceptions of the medical school learning environment may change over time and be associated with students' year of training and may differ significantly depending on the student's gender or race/ethnicity...
March 20, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28316252/relationship-between-family-history-of-alcohol-addiction-parents-education-level-and-smartphone-problem-use-scale-scores
#11
Ashley Beison, David J Rademacher
Background and aims Smartphones are ubiquitous. As smartphones increased in popularity, researchers realized that people were becoming dependent on their smartphones. The purpose here was to provide a better understanding of the factors related to problematic smartphone use (PSPU). Methods The participants were 100 undergraduates (25 males, 75 females) whose ages ranged from 18 to 23 (mean age = 20 years). The participants completed questionnaires to assess gender, ethnicity, year in college, father's education level, mother's education level, family income, age, family history of alcoholism, and PSPU...
March 20, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28315576/control-of-lower-extremity-edema-in-patients-with-diabetes-double-blind-randomized-controlled-trial-assessing-the-efficacy-of-mild-compression-diabetic-socks
#12
Stephanie C Wu, Ryan T Crews, Melissa Skratsky, Julia Overstreet, Sai V Yalla, Michelle Winder, Jacquelyn Ortiz, Charles A Andersen
AIMS: Persons with diabetes frequently present with lower extremity (LE) edema; however, compression therapy is generally avoided for fear of compromising arterial circulation in a population with a high prevalence of peripheral arterial disease. This double blind randomized controlled trial (RCT) assessed whether diabetic socks with mild compression could reduce LE edema in patients with diabetes without negatively impacting vascularity. METHODS: Eighty subjects with LE edema and diabetes were randomized to receive either mild-compression knee high diabetic socks (18-25mmHg) or non-compression knee high diabetic socks...
February 27, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28314554/an-evaluation-of-the-absolute-and-relative-stability-of-alexithymia-over-11years-in-a-finnish-general-population
#13
A Hiirola, S Pirkola, M Karukivi, N Markkula, R M Bagby, M Joukamaa, A Jula, E Kronholm, S Saarijärvi, J K Salminen, J Suvisaari, G Taylor, A K Mattila
OBJECTIVE: We investigated if alexithymia, a personality construct with difficulties in emotional processing, is stable in the general population. METHODS: Altogether 3083 unselected subjects aged 30 and older in Finland completed the 20-item Toronto Alexithymia Scale (TAS-20) in the longitudinal Health 2000 and Health 2011 general population surveys (BRIF8901). The stability of alexithymia at the 11-year follow-up was assessed with t-tests, correlations, and separate linear regression models with base-line and follow-up age, gender, marital status, education, and 12-month depressive and anxiety disorders as confounders...
April 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28296926/relationship-between-decreased-lower-extremity-muscle-mass-and-knee-pain-severity-in-both-the-general-population-and-patients-with-knee-osteoarthritis-findings-from-the-knhanes-v-1-2
#14
Yun-Hong Cheon, Hyun-Ok Kim, Young Sun Suh, Min Gyo Kim, Wan-Hee Yoo, Rock Bum Kim, Hyun-Su Yang, Sang-Il Lee, Ki-Soo Park
OBJECTIVE: To identify the prevalence of and risk factors for knee pain and radiographic knee osteoarthritis (RKOA) and to investigate the relationship between decreased lower extremity muscle mass (DLEM) and knee pain severity. METHODS: Using data from the Korea National Health and Nutrition Examination Survey, 3,278 participants who were ≥50 years old and who underwent dual x-ray absorptiometry, plain knee radiographs and completed a knee pain questionnaire were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28291297/-reliability-and-validity-indicators-of-berkeley-expressivity-questionnaire-in-the-context-of-culture-and-gender
#15
Şebnem Tunay Akan, Elif Barışkın
PURPOSE: The Berkeley Expressivity Questionaire (BEQ) was a scale, developed by Gross and John (1995) to measure emotion expression. The purpose of the present study was to investigate reliability and validity indicators of the BEQ in our culture. METHOD: The sample composed of 213 (115 women) people whose average of age 35. The people were voluntered for the study and lived within the borders of Izmir. The validity indicators of the questionaire were investigated through explanatory and confirmatory factor analyses, gender differences between the scores and correlational analyses on Difficulties in Emotion Regulation Scale (DERS)...
2017: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/28289681/thanatophobia-death-anxiety-in-the-elderly-the-problem-of-the-child-s-inability-to-assess-their-own-parent-s-death-anxiety-state
#16
Gary Sinoff
Thanatophobia is omnipresent in our lives. Research has shown separate but connected constructs: fear of death or fear of the dying process. The influences on death anxiety are varied including religiosity, gender, psychological state, and age. It is often assumed by the children of the elderly that the fear of death is prevalent in their parents. Daily the medical staff encounters the presence of death anxiety: from family members or the staff itself. In order to understand this phenomenon, a three-tier study was conducted on non-terminal elderly inpatients in an acute geriatric care ward...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28289599/quantitative-measures-of-walking-and-strength-provide-insight-into-brain-corticospinal-tract-pathology-in-multiple-sclerosis
#17
Nora E Fritz, Jennifer Keller, Peter A Calabresi, Kathleen M Zackowski
At least 85% of individuals with multiple sclerosis report walking dysfunction as their primary complaint. Walking and strength measures are common clinical measures to mark increasing disability or improvement with rehabilitation. Previous studies have shown an association between strength or walking ability and spinal cord MRI measures, and strength measures with brainstem corticospinal tract magnetization transfer ratio. However, the relationship between walking performance and brain corticospinal tract magnetization transfer imaging measures and the contribution of clinical measurements of walking and strength to the underlying integrity of the corticospinal tract has not been explored in multiple sclerosis...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28288227/-physical-activity-patterns-of-school-adolescents-validity-reliability-and-percentiles-proposal-for-their-evaluation
#18
Marco Cossío Bolaños, Jorge Méndez Cornejo, Cristian Luarte Rocha, Rodrigo Vargas Vitoria, Bernabé Canqui Flores, Rossana Gomez Campos
Regular physical activity (PA) during childhood and adolescence is important for the prevention of non-communicable diseases and their risk factors. OBJECTIVES: To validate a questionnaire for measuring patterns of PA, verify the reliability, comparing the levels of PA aligned with chronological and biological age, and to develop percentile curves to assess PA levels depending on biological maturation. SUBJECTS AND METHOD: Descriptive cross-sectional study was performed on a sample non-probabilistic quota of 3,176 Chilean adolescents (1685 males and 1491 females), with a mean age range from 10...
February 2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28285254/the-predictive-role-of-daily-cognitive-stimulation-on-executive-functions-in-bipolar-disorder
#19
Charles Cotrena, Laura Damiani Branco, André Ponsoni, Flávio Milman Shansis, Renata Kochhann, Rochele Paz Fonseca
This study aimed to estimate the predictive role of clinical and demographic variables on the three core executive functions (EF) - working memory (WM), inhibitory control (IC) and cognitive flexibility (CF) - in bipolar disorder (BD). The sample consisted of 38 patients with BD type I, 39 with BD type II, and 106 control participants with no mood disorders. Subjects completed the Hayling Test, Trail Making Test, Digit Span Backwards, Sentence Word Span Test, and Stroop Color-Word Test. Composite scores for WM, IC and CF were calculated, and their correlations with clinical and demographic variables were analyzed...
March 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28284358/social-cognitive-determinants-of-healthy-eating%C3%A2-behaviors-in-late-adolescents-a%C3%A2-gender%C3%A2-perspective
#20
Pananda Chansukree, Nitinai Rungjindarat
OBJECTIVE: To investigate the impact of social cognitive determinants on healthy eating behaviors among adolescents, with a specific focus on gender differences. DESIGN: Cross-sectional analysis of survey data. SETTING: Bangkok, Thailand. PARTICIPANTS: A total of 1,200 undergraduates from public and private universities. MAIN OUTCOME MEASURES: Dependent variable: healthy eating behaviors measured by the total score of 11 items adapted from the Australian Dietary Guideline Index...
March 2017: Journal of Nutrition Education and Behavior
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