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"Cognitive activity" aging

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https://www.readbyqxmd.com/read/28322422/use-it-or-lose-it-cognitive-activity-as-a-protec-tive-factor-for-cognitive-decline-associated-with-alzheimer-s-disease
#1
Panagiota Mistridis, Jutta Mata, Stefan Neuner-Jehle, Jean-Marie Annoni, Andreas Biedermann, Irene Bopp-Kistler, Dominique Brand, Andrea Brioschi Guevara, Hedi Decrey-Wick, Jean-François Démonet, Ulrich Hemmeter, Reto W Kressig, Brian Martin, Luca Rampa, Egemen Savaskan, Andreas Stuck, Philipp Tschopp, Dina Zekry, Andreas Monsch
Because of the worldwide aging of populations, Alzheimer's disease and other dementias constitute a devastating experience for patients and families as well as a major social and economic burden for both healthcare systems and society. Multiple potentially modifiable cardiovascular and lifestyle risk factors have been associated with this disease. Thus, modifying these risk factors and identifying protective factors represent important strategies to prevent and delay disease onset and to decrease the social burden...
March 21, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28282912/predictors-of-nightly-subjective-objective-sleep-discrepancy-in-poor-sleepers-over-a-seven-day-period
#2
Vanessa Herbert, Daniel Pratt, Richard Emsley, Simon D Kyle
This study sought to examine predictors of subjective/objective sleep discrepancy in poor sleepers. Forty-two individuals with insomnia symptoms (mean age = 36.2 years, 81% female) were recruited to take part in a prospective study which combined seven days of actigraphy with daily assessment of sleep perceptions, self-reported arousal, sleep effort, and mood upon awakening. A high level of intra-individual variability in measures of sleep discrepancy was observed. Multilevel modelling revealed that higher levels of pre-sleep cognitive activity and lower mood upon awakening were significantly and independently predictive of the underestimation of total sleep time...
March 9, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28282326/effects-of-mental-fatigue-on-endurance-performance-in-the-heat
#3
Jeroen Van Cutsem, Kevin De Pauw, Luk Buyse, Samuele Marcora, Romain Meeusen, Bart Roelands
PURPOSE: Mental fatigue is a psychobiological state caused by prolonged periods of demanding cognitive activity and has been observed to decrease time-trial (TT) endurance performance by ~3,5% in normal ambient temperatures. Recently it has been suggested that heat may augment the negative effect of mental fatigue on cognitive performance, raising the question whether it may also amplify the effect of mental fatigue on TT-performance. METHODS: In 30 °C and 30% relative humidity, ten endurance-trained male athletes (Age: 22 ± 3 y; Wmax: 332 ± 41 W) completed two experimental conditions: intervention (I; 45-min Stroop task) and control (C; 45-min documentary)...
March 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28263928/the-spatiotemporal-substrates-of-autobiographical-recollection-using-event-related-ica-to-study-cognitive-networks-in-action
#4
Chris Tailby, Genevieve Rayner, Sarah Wilson, Graeme Jackson
Higher cognitive functions depend upon dynamically unfolding brain network interactions. Autobiographical recollection - the autonoetic re-experiencing of context rich, emotionally laden, personally experienced episodes - is an excellent example of such a process. Autobiographical recollection unfolds over time, with different cognitive processes engaged at different times throughout. In this paper we apply a recently developed analysis technique - event related independent components analysis (eICA) - to study the spatiotemporal dynamics of neural activity supporting autobiographical recollection...
March 2, 2017: NeuroImage
https://www.readbyqxmd.com/read/28151002/lack-of-associations-between-modifiable-risk-factors-and-dementia-in-the-very-old-findings-from-the-cambridge-city-over-75s-cohort-study
#5
Kay Deckers, Sebastian Köhler, Martin van Boxtel, Frans Verhey, Carol Brayne, Jane Fleming
OBJECTIVES: To investigate the association between modifiable risk and protective factors and severe cognitive impairment and dementia in the very old. Additionally, the present study tests the predictive validity of the 'LIfestyle for BRAin health' (LIBRA) score, an index developed to assess an individual's dementia prevention potential. METHOD: Two hundred seventy-eight individuals aged 85 years or older from the Cambridge City over-75s cohort study were followed-up until death...
February 2, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28131014/executive-function-performance-and-change-in-aging-is-predicted-by-apolipoprotein-e-intensified-by-catechol-o-methyltransferase-and-brain-derived-neurotrophic-factor-and-moderated-by-age-and-lifestyle
#6
Shraddha Sapkota, Lars Bäckman, Roger A Dixon
Recent studies have reported several genetic, health, and aging interaction effects in predicting cognitive performance and change. We used an accelerated longitudinal design to examine interactions among genetic, lifestyle, and aging for executive function (EF) in non-demented older adults (n = 634; age range = 53-95 years). The polymorphisms were apolipoprotein E (APOE), catechol-O-methyltransferase (COMT), and brain-derived neurotrophic factor (BDNF). We tested (1) independent and additive effects of APOE, COMT, and BDNF and (2) APOE effect modification for COMT + BDNF, on EF performance and 9-year change as separated by age and lifestyle activities...
April 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28067190/leisure-activities-education-and-cognitive-impairment-in-chinese-older-adults-a-population-based-longitudinal-study
#7
Xinyi Zhu, Chengxuan Qiu, Yi Zeng, Juan Li
BACKGROUND: We examine the association between leisure-time activities and the risk of developing cognitive impairment among Chinese older people, and further investigate whether the association varies by educational level. METHODS: This follow-up study included 6,586 participants (aged 79.5 ± 9.8 years, range 65-105 years, 51.7% female) of the Chinese Longitudinal Healthy Longevity Survey who were aged ≥65 years and were free of cognitive impairment in 2002...
January 9, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28025282/memory-resilience-to-alzheimer-s-genetic-risk-sex-effects-in-predictor-profiles
#8
Kirstie L McDermott, G Peggy McFall, Shea J Andrews, Kaarin J Anstey, Roger A Dixon
OBJECTIVES: Apolipoprotein E (APOE) ɛ4 and Clusterin (CLU) C alleles are risk factors for Alzheimer's disease (AD) and episodic memory (EM) decline. Memory resilience occurs when genetically at-risk adults perform at high and sustained levels. We investigated whether (a) memory resilience to AD genetic risk is predicted by biological and other risk markers and (b) the prediction profiles vary by sex and AD risk variant. METHOD: Using a longitudinal sample of nondemented adults (n = 642, aged 53-95) we focused on memory resilience (over 9 years) to 2 AD risk variants (APOE, CLU)...
December 26, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28011290/the-effect-of-a-specialized-content-knowledge-workshop-on-teaching-and-learning-basic-life-support-in-elementary-school-a-cluster-randomized-controlled-trial
#9
Peter Iserbyt, Lieselot Theys, Phillip Ward, Nathalie Charlier
BACKGROUND: Research investigating the effect of specialised content knowledge (SCK) on teaching and learning Basic Life Support (BLS) is lacking. PURPOSE: To investigate the effect of a specialised content knowledge workshop on teaching behaviour, lesson context and student learning of BLS. Specialised content knowledge comprises knowledge of content progressions, skill analysis, and how to correct common errors. METHODS: A cluster randomized controlled trial...
December 20, 2016: Resuscitation
https://www.readbyqxmd.com/read/27996319/hypoglycemia-in-older-adults-with-type-1-diabetes
#10
Stephanie N DuBose, Ruth S Weinstock, Roy W Beck, Anne L Peters, Grazia Aleppo, Richard M Bergenstal, Henry Rodriguez, Joseph F Largay, Elaine M Massaro, Irl B Hirsch
BACKGROUND: Hypoglycemia is a major concern in older adults with type 1 diabetes (T1D) and there is limited knowledge in this population. We examined data from 199 adults, ≥60 years of age, who participated in a T1D Exchange study assessing factors associated with severe hypoglycemia (SH) in older adults with T1D: 100 with SH in the prior year and 99 with no SH in prior 3 years (mean age 68; mean diabetes duration 40 years; 47% female; 92% non-Hispanic white). Hypoglycemia was assessed with up to 14 days of blinded continuous glucose monitoring (CGM)...
December 2016: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/27835621/interpreting-the-influence-of-race-and-cognitive-activity-on-neurocognition-in-adults-aging-with-hiv
#11
David E Vance
No abstract text is available yet for this article.
January 28, 2017: AIDS
https://www.readbyqxmd.com/read/27835616/association-of-cognitive-activity-and-neurocognitive-function-in-blacks-and-whites-with-hiv
#12
Kristin R Krueger, Oluwatoyin Adeyemi, Sue Leurgans, Raj C Shah, Antonio D Jimenez, Lawrence Ouellet, Alan L Landay, David A Bennett, Lisa L Barnes
OBJECTIVE: Older persons with HIV are at risk for impaired cognition, yet there is limited information on modifiable factors associated with neurocognitive function in this group. DESIGN: This is a cross-sectional observational study of cognitive activities and neurocognitive function. METHODS: We examined the relation between frequency of cognitive activity and current neurocognitive performance in 176 older persons with HIV [70% African American, 76% men; mean age = 58...
January 28, 2017: AIDS
https://www.readbyqxmd.com/read/27785029/impaired-social-cognition-in-anorexia-nervosa-patients
#13
Sayo Hamatani, Masahito Tomotake, Tomoya Takeda, Naomi Kameoka, Masashi Kawabata, Hiroko Kubo, Yukio Tada, Yukiko Tomioka, Shinya Watanabe, Tetsuro Ohmori
BACKGROUND: The purpose of this study was to investigate the characteristics of social cognition in patients with anorexia nervosa (AN). METHODS: Eighteen female patients with AN (mean age =35.4±8.6 years) and 18 female healthy controls (HC) (mean age =32.8±9.4 years) participated in the study. Their social cognition was assessed with the Social Cognition Screening Questionnaire (SCSQ). RESULTS: The results showed that total score of the SCSQ and scores of theory of mind and metacognition were significantly lower in AN group than those in HC group...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27757821/distinct-effects-of-late-adulthood-cognitive-and-physical-activities-on-gray-matter-volume
#14
Eider M Arenaza-Urquijo, Robin de Flores, Julie Gonneaud, Miranka Wirth, Valentin Ourry, William Callewaert, Brigitte Landeau, Stéphanie Egret, Florence Mézenge, Béatrice Desgranges, Gaël Chételat
Engagement in cognitive activity (CA) and physical activity (PA) during the lifespan may counteract brain atrophy later in life. Here, we investigated engagement in CA and PA during late adulthood in association with gray matter volume (GM) in normal older adults, with special focus on the hippocampus. Forty-five cognitively normal older individuals (mean age: 72) underwent T1-weighted MRI and self-reported CA and PA assessment. Whole brain voxel-wise multiple regression models were carried out to assess the relationships between CA, PA and GM volume adjusted by age and sex...
October 18, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27744301/influences-on-diet-quality-in-older-age-the-importance-of-social-factors
#15
Ilse Bloom, Mark Edwards, Karen A Jameson, Holly E Syddall, Elaine Dennison, Catharine R Gale, Janis Baird, Cyrus Cooper, Avan Aihie Sayer, Sian Robinson
BACKGROUND: poor diet quality is common among older people, but little is known about influences on food choice, including the role of psychosocial factors at this age. OBJECTIVE: to identify psychosocial correlates of diet quality in a community-dwelling population of men and women aged 59-73 years; to describe relationships with change in diet quality over 10 years. DESIGN: Longitudinal cohort, Hertfordshire Cohort Study (HCS). SUBJECTS: HCS participants assessed at baseline (1998-2003: 1,048 men, 862 women); 183 men and 189 women re-assessed in 2011...
October 15, 2016: Age and Ageing
https://www.readbyqxmd.com/read/27714849/psychosocial-or-clinico-demographic-factors-related-to-neuropsychiatric-symptoms-in-patients-with-alzheimer-s-disease-needing-interventional-treatment-analysis-of-the-catie-ad-study
#16
Tomoyuki Nagata, Shinichiro Nakajima, Shunichiro Shinagawa, Eric Plitman, Ariel Graff-Guerrero, Masaru Mimura, Kazuhiko Nakayama
OBJECTIVE: This study sought to determine psychosocial and clinico-demographic factors related to each symptomatic cluster (i.e., aggressiveness, psychosis, apathy/eating problems, and emotion/disinhibition) of neuropsychiatric symptoms (NPSs) in patients with Alzheimer's disease (AD) needing interventional treatment against their agitation or psychotic symptoms. These clusters were classified from 12 Neuropsychiatric Inventory (NPI) subscores in our previous study using the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer's Disease (CATIE-AD) dataset...
October 7, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27532469/interventions-incorporating-physical-and-cognitive-elements-to-reduce-falls-risk-in-cognitively-impaired-older-adults-a-systematic-review
#17
Vicky Booth, Victoria Hood, Fiona Kearney
BACKGROUND: Cognitive impairment is a risk factor for falls. Older adults with cognitive impairment (such as dementia) have an increased risk of falling compared with age-matched individuals without a cognitive impairment. To reduce falls in this population, interventions could theoretically target and train both physical and cognitive abilities. Combining and addressing cognitive components in falls rehabilitation is a novel and emerging area of healthcare. OBJECTIVES: The objective of this review was to identify the effectiveness of combined cognitive and physical interventions on the risk of falls in cognitively impaired older adults...
May 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27524792/promoting-brain-health-through-exercise-and-diet-in-older-adults-a-physiological-perspective
#18
Philippa A Jackson, Vincent Pialoux, Dale Corbett, Lauren Drogos, Kirk I Erickson, Gail A Eskes, Marc J Poulin
The rise in incidence of age-related cognitive impairment is a global health concern. Ageing is associated with a number of changes in the brain that, collectively, contribute to the declines in cognitive function observed in older adults. Structurally, the ageing brain atrophies as white and grey matter volumes decrease. Oxidative stress and inflammation promote endothelial dysfunction thereby hampering cerebral perfusion and thus delivery of energy substrates and nutrients. Further, the development of amyloid plaques and neurofibrillary tangles contributes to neuronal loss...
August 15, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27502527/delirium-in-elderly-patients-association-with-educational-attainment
#19
Sónia Martins, José Artur Paiva, Mário R Simões, Lia Fernandes
OBJECTIVE: Among cognitive reserve markers, educational attainment is the most widely studied, with several studies establishing a strong association with risk of dementia. However, it has not yet been fully examined in delirium. This study aims to analyse the relationship between educational attainment and delirium. METHODS: The study included elderly hospitalised patients admitted (≥48 h) into an intermediate care unit (IMCU) of Intensive Care Medicine Service...
August 9, 2016: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/27426008/docosahexaenoic-acid-one-molecule-diverse-functions
#20
Michio Hashimoto, Shahdat Hossain, Abdullah Al Mamun, Kentaro Matsuzaki, Hiroyuki Arai
Docosahexaenoic acid (DHA, C22:6, ω-3) is a highly polyunsaturated omega-3 fatty acid. It is concentrated in neuronal brain membranes, for which reason it is also referred to as a "brain food". DHA is essential for brain development and function. It plays an important role in improving antioxidant and cognitive activities of the brain. DHA deficiency occurs during aging and dementia, impairs memory and learning, and promotes age-related neurodegenerative diseases, including Alzheimer's disease (AD). For about two decades, we have reported that oral administration of DHA increases spatial memory acquisition, stimulates neurogenesis, and protects against and reverses memory impairment in amyloid β peptide-infused AD rat models by decreasing amyloidogenesis and protects against age-related cognitive decline in the elderly...
July 17, 2016: Critical Reviews in Biotechnology
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