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ABR bone conduction

Rensa Chen, Martin Schwander, Mary F Barbe, Marion M Chan
Globally, a body of comparative case-control studies suggests that rheumatoid arthritis (RA) patients are more prone to developing hearing loss (HL). However, experimental evidence that supports this hypothesis is still lacking because the human auditory organ is not readily accessible. The aim of this study was to determine the association between bone damage to the ossicles of the middle ear and HL, using a widely accepted murine model of collagen-induced arthritis (RA mice). Diarthrodial joints in the middle ear were examined with microcomputer tomography (microCT), and hearing function was assessed by auditory brainstem response (ABR)...
2016: PloS One
Kensi M Cobb, Andrew Stuart
OBJECTIVES: The purpose of the study was to generate normative auditory brainstem response (ABR) wave component peak latency and amplitude values for neonates with air- and bone-conducted CE-Chirps and air-conducted CE-Chirp octave band stimuli (i.e., 500, 1000, 2000, and 4000 Hz). A second objective was to compare neonate ABRs to CE-Chirp stimuli with ABR responses to traditional click and tone burst stimuli with the same stimulus parameters. DESIGN: Participants were 168 healthy neonates...
August 22, 2016: Ear and Hearing
Kensi M Cobb, Andrew Stuart
OBJECTIVES: The purpose of the study was to examine the differences in auditory brainstem response (ABR) latency and amplitude indices to the CE-Chirp stimuli in neonates versus young adults as a function of stimulus level, rate, polarity, frequency and gender. DESIGN: Participants were 168 healthy neonates and 20 normal-hearing young adults. ABRs were obtained to air- and bone-conducted CE-Chirps and air-conducted CE-Chirp octave band stimuli. The effects of stimulus level, rate, and polarity were examined with air-conducted CE-Chirps...
August 22, 2016: Ear and Hearing
Kensi M Cobb, Andrew Stuart
PURPOSE: The purpose of this study was to compare auditory brainstem response (ABR) thresholds to air- and bone-conducted CE-Chirps in neonates and adults. METHOD: Thirty-two neonates with no physical or neurologic challenges and 20 adults with normal hearing participated. ABRs were acquired with a starting intensity of 30 dB normal hearing level (nHL). The lowest stimulus intensity level at which a wave V was identifiable and replicable was considered the ABR threshold...
August 1, 2016: Journal of Speech, Language, and Hearing Research: JSLHR
Elisa Biamino, Andrea Canale, Michelangelo Lacilla, Annalisa Marinosci, Federico Dagna, Lorenzo Genitori, Paola Peretta, Margherita Silengo, Roberto Albera, Giovanni Battista Ferrero
OBJECTIVE: To assess the audiological profile in a cohort of children affected by syndromic craniosynostosis. METHODS: Eleven children with Apert syndrome (n=4), Saethre-Chotzen syndrome (n=3), Muenke syndrome (n=2), Crouzon syndrome (n=1) and Pfeiffer syndrome type 1 (n=1) were submitted to a complete audiologic evaluation including otoscopy, pure-tone audiometry, tympanometry and acoustic reflex testing, ABR, otoacustic emissions, temporal bone High Resolution CT (HRCT) scan...
June 2016: International Journal of Pediatric Otorhinolaryngology
Ronen Perez, Cahtia Adelman, Haim Sohmer
Conclusion Cochlea can be directly excited by fluid (soft-tissue) stimulation. Objective To determine whether there is no difference in auditory-nerve-brainstem evoked response (ABR) thresholds to fluid stimulation between normal and animal models of post radical-mastoidectomy, as seen in a previous human study. Background It has been shown in humans that hearing can be elicited with stimulation to fluid in the external auditory meatus (EAM), and radical-mastoidectomy cavity. These groups differed in age, initial hearing, and drilling exposure...
2016: Acta Oto-laryngologica
M J Bergin, P A Bird, S M Vlajkovic, P R Thorne
Permanent high frequency (>4 kHz) sensorineural hearing loss following middle ear surgery occurs in up to 25% of patients. The aetiology of this loss is poorly understood and may involve transmission of supra-physiological forces down the ossicular chain to the cochlea. Investigating the mechanisms of this injury using animal models is challenging, as evaluating cochlear function with evoked potentials is confounded when ossicular manipulation disrupts the normal air conduction (AC) pathway. Bone conduction (BC) using clinical bone vibrators in small animals is limited by poor transducer output at high frequencies sensitive to trauma...
December 2015: Hearing Research
Mick Metselaar, Gülnez Demirtas, Teun van Immerzeel, Marc van der Schroeff
OBJECTIVE: This study investigates the most appropriate audiometric criterion in deciding which patients with asymmetric hearing loss should be referred to MRI to exclude a lesion in the cerebellopontine angle (CPA). Careful selection of patients could improve resource utilization while preventing unnecessary investigations with accompanying burden and costs. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center. PATIENTS: Of all the patients who were referred to our clinic between 1997 and 2012, the records were reviewed of those who underwent pure-tone audiometry, auditory brainstem response (ABR) testing, and had a Gadolinium-enhanced MRI of the CPA...
December 2015: Otology & Neurotology
Junming Chen, Yuanxin Zhao, Xiaowei Zhou, Lingmei Tan, Zeying Ou, Youjun Yu, Yuejian Wang
OBJECTIVES/HYPOTHESIS: To investigate the hearing protective effects of methylprednisolone use during radiotherapy in patients with nasopharyngeal carcinoma. STUDY DESIGN: Prospective, controlled clinical study. METHODS: Fifty-three patients with nasopharyngeal carcinoma (106 ears). Twenty-five patients (50 ears) received radiotherapy with intravenous methylprednisolone for 14 days, and another 28 patients (56 ears) received radiotherapy alone...
January 2016: Laryngoscope
Lichun Zhang, Na Gao, Yanbo Yin, Lin Yang, Youzhou Xie, Ying Chen, Peidong Dai, Tianyu Zhang
Previous researches focusing on BC hearing mechanisms proved that the two routes, (1) EAC sound radiation and (2) inertial of ossicular chain, partially contribute to normal BC hearing. Therefore, the BC hearing for those patients with congenital aural atresia should partially decrease theoretically due to their abnormal anatomy. However, there are not many studies which mention these patients' BC hearing up till now. The objective of this study is to investigate congenital aural atresia patient's BC hearing by analysis of pre-surgical audiogram and to study their potential BC hearing mechanisms using animal modeling and their ABR measurements...
July 2016: European Archives of Oto-rhino-laryngology
Yibei Wang, Xiaowei Chen, Yue Fan, Zhen Wang
OBJECTIVE: To evaluate auditory developments and the effectiveness of children with congenital bilateral aural atresia after using softband Ponto and to compare them with children with normal hearing. METHOD: Twenty patients (age ranging from 3 months to 21 months ) with bilateral aural atresia were studied. The air and bone auditory thresholds were assessed by auditory brain stem response (ABR). The infant-todder meaning auditory integration scale (IT-MAIS) was used to evaluate the auditory development at three time levels: baseline, 3 months and 6 months...
February 2015: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Alaaeldin M Elsayed, Lisa L Hunter, Douglas H Keefe, M Patrick Feeney, David K Brown, Jareen K Meinzen-Derr, Kelly Baroch, Maureen Sullivan-Mahoney, Kara Francis, Leigh G Schaid
OBJECTIVES: To study normative thresholds and latencies for click and tone-burst auditory brainstem response (TB-ABR) for air and bone conduction in normal infants and those discharged from neonatal intensive care units, who passed newborn hearing screening and follow-up distortion product otoacoustic emission. An evoked potential system (Vivosonic Integrity) that incorporates Bluetooth electrical isolation and Kalman-weighted adaptive processing to improve signal to noise ratios was employed for this study...
July 2015: Ear and Hearing
Keiko Tsukamoto
There are many diseases specific to childhood. Therefore, there are several specific examinations which are not performed in adults. In this article, we introduce some examinations specific to the neonatal period. Newborn mass-screening using tandem mass spectrometry is conducted to diagnose congenital metabolic error before onset early after birth and minimize the influence of disturbance. Tandem mass spectrometry is performed to detect amino acid metabolism disturbance, urea cycle disorder, organic acid metabolism disturbance, and fatty acid metabolism disturbance...
August 2014: Rinsho Byori. the Japanese Journal of Clinical Pathology
Mina Park, Kyu-Hee Han, Hyunseo Jung, Mee-Hee Kim, Hyun-Kyung Chang, Shin Hye Kim, Moo Kyun Park, Jun Ho Lee
OBJECTIVE: Numerous studies have shown the superiority of a 1000-Hz frequency probe tone for evaluating the middle ear status of infants. However, most of these studies examined Caucasian populations. This study validated the 1000-Hz probe tone and evaluated the age at which it should be used in Korean infants. METHODS: Data from 83 infants (43 males, 40 females; mean age 9.2±6.2 (range 1-30) months, 165 ears) were analyzed. Tympanograms were classified according to Baldwin's modification of the method of Marchant et al...
January 2015: International Journal of Pediatric Otorhinolaryngology
Ronen Perez, Cahtia Adelman, Shai Chordekar, Marrigje A de Jong, Haim Sohmer
BACKGROUND: Active middle ear implants such as the vibrant sound bridge (VSB) have been placed on the round window (RW) in patients with conductive or mixed hearing loss, with satisfactory hearing results. Several observations show that the mechanism of RW stimulation is not completely understood. The purpose of the present study was to compare different coupling procedures between the transducer and the RW in order to contribute to an understanding of the mechanism of RW stimulation...
September 2014: Journal of Basic and Clinical Physiology and Pharmacology
Frank Rattay, Simon M Danner
Early neural responses to acoustic signals can be electrically recorded as a series of waves, termed the auditory brainstem response (ABR). The latencies of the ABR waves are important for clinical and neurophysiological evaluations. Using a biophysical model of transmembrane currents along spiral ganglion cells, we show that in human (i) the non-myelinated somatic regions of type I cells, which innervate inner hair cells, predominantly contribute to peak I, (ii) the supra-strong postsynaptic stimulating current (400 pA) and transmembrane currents of the myelinated peripheral axons of type I cells are an order smaller; such postsynaptic currents correspond to the short latencies of a small recordable ABR peak I', (iii) the ABR signal involvement of the central axon of bipolar type I cells is more effective than their peripheral counterpart as the doubled diameter causes larger transmembrane currents and a larger spike dipole-length, (iv) non-myelinated fibers of type II cells which innervate the outer hair cells generate essentially larger transmembrane currents but their ABR contribution is small because of the small ratio type II/type I cells, low firing rates and a short dipole length of spikes propagating slowly in non-myelinated fibers...
September 2014: Hearing Research
Kensi M Cobb, Andrew Stuart
OBJECTIVE: The purpose of this study was to examine the test-retest reliability of auditory brainstem responses (ABRs) to air- and bone-conducted chirp stimuli in newborns as a function of intensity. DESIGN: A repeated measures quasi-experimental design was employed. STUDY SAMPLE: Thirty healthy newborns participated. ABRs were evoked using 60, 45, and 30 dB nHL air-conducted CE-Chirps and 45, 30, and 15 dB nHL bone-conducted CE-Chirps at a rate of 57...
November 2014: International Journal of Audiology
Kyung Han Cha, Tack Geun Cho, Chang Hyun Kim, Ho Kook Lee, Jae Gon Moon
OBJECTIVE: As a conservative treatment of compression fractures, absolute bed rest (ABR) for a certain period has been recommended, but no guideline on the period has yet been established. Considering that a long ABR period may adversely affect patients, the difference in prognosis according to the ABR period was investigated in this study. METHODS: A prospective study was conducted who were diagnosed with compression fracture. Groups A and B were put on ABR (one week for group A and two weeks for group B)...
September 2013: Korean Journal of Spine
Ying Zhang, Yue Fan, Yibei Wang, Xiaowei Chen
OBJECTIVE: To retrospectively analyze the auditory and speech development of young children with bilateral congenital aural atresia after using bone-anchored hearing aid (BAHA) softband. METHODS: From August 2010 to January 2013, a total of 12 patients aged at a range of 3 months to 6 years with bilateral aural atresia using BAHA softband were divided into under 4-year-old group (n = 7, an average age of 14 months) and over 4-year-old group (n = 5, an average age of 77 months)...
February 18, 2014: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Ronen Perez, Cahtia Adelman, Shai Chordekar, Reuven Ishai, Haim Sohmer
Clinical conditions have been described in which one of the two cochlear windows is immobile (otosclerosis) or absent (round window atresia), but nevertheless bone conduction (BC) thresholds are relatively unaffected. To clarify this apparent paradox, experimental manipulations which would severely impede several of the classical osseous mechanisms of BC were induced in fat sand rats, including discontinuity or immobilization of the ossicular chain, coupled with window fixation. Effects of these manipulations were assessed by recording auditory nerve brainstem evoked response (ABR) thresholds to stimulation by air conduction (AC), by osseous BC and by non-osseous BC (also called soft tissue conduction-STC) in which the BC bone vibrator is applied to skin sites...
April 2015: European Archives of Oto-rhino-laryngology
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