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https://www.readbyqxmd.com/read/29298186/evaluation-of-the-relative-abuse-of-an-oros%C3%A2-extended-release-hydromorphone-hci-product-results-from-three-post-market-surveillance-studies
#1
Stephen F Butler, Emily C McNaughton, Ryan A Black, Theresa A Cassidy
OBJECTIVE: Formulating prescription opioids to limit abuse remains a priority. OROS® extended-release (ER) hydromorphone HCl (EXALGO®) may have low abuse potential. Three post-marketing studies of the relative abuse liability of OROS hydromorphone ER were conducted. METHODS: Estimates of abuse, unadjusted and adjusted for prescription volume, were generated for OROS hydromorphone ER and comparators from Q2 2010 through Q2 2014 for a high-risk, substance abuse treatment population and the general population using poison control center data...
January 2, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/22795050/safety-and-tolerability-of-once-daily-oros-%C3%A2-hydromorphone-extended-release-in-opioid-tolerant-adults-with-moderate-to-severe-chronic-cancer-and-noncancer-pain-pooled-analysis-of-11-clinical-studies
#2
Srinivas R Nalamachu, Michael Kutch, Martin E Hale
CONTEXT: The efficacy and tolerability of once-daily hydromorphone extended release (ER) (OROS(®) hydromorphone ER, Exalgo(®), Mallinckrodt Brand Pharmaceuticals, Inc., Hazelwood, MO) in patients with chronic cancer and noncancer pain have been reported in previous studies. OBJECTIVES: The objective of this analysis was to assess the pooled safety data of OROS hydromorphone ER in opioid-tolerant patients with chronic cancer and noncancer pain. METHODS: Safety results were pooled from 11 clinical studies in opioid-tolerant patients: one 12-week, double-blind, placebo-controlled study; three active-controlled studies; and seven uncontrolled studies (durations of three to 52 weeks)...
December 2012: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/21836545/extended-release-hydromorphone-exalgo-for-pain
#3
REVIEW
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No abstract text is available yet for this article.
August 25, 2011: Medical Letter on Drugs and Therapeutics
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