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https://www.readbyqxmd.com/read/29028813/evaluation-of-shedding-tissue-burdens-and-humoral-immune-response-in-goats-after-experimental-challenge-with-the-virulent-brucella-melitensis-strain-16m-and-the-reduced-virulence-vaccine-strain-rev-1
#1
Jennifer L Higgins, Mercedes Gonzalez-Juarrero, Richard A Bowen
Brucella melitensis is the causative agent of brucellosis in small ruminants and is of considerable economic and public health importance in many countries worldwide. The control of disease in humans depends on the control of disease in livestock; however, few counties with endemic B. melitensis infection have been able to successfully eradicate this pathogen. This underscores the need for further research on the pathogenesis of both virulent and vaccine strains of B. melitensis in the small ruminant host. The aim of the present study was to characterize clinical effects, tissue colonization, shedding, and humoral immune response following B...
2017: PloS One
https://www.readbyqxmd.com/read/29028681/polybrominated-diphenyl-ether-concentrations-in-human-breast-milk-specimens-worldwide
#2
Jiyan Zhang, Lu Chen, Lin Xiao, Fengxiu Ouyang, Qing-Ying Zhang, Zhong-Cheng Luo
BACKGROUND: Polybrominated diphenyl ethers (PBDEs) are a class of flame retardants of ubiquitous presence in numerous consumer products. PBDEs may impair neurodevelopment in infants. There is a lack of meta-analysis on PBDE concentrations in human breast milk worldwide. We aimed to summarize global research data on PBDE concentrations in human breast milk specimens in recent years. METHODS: We conducted a systematic review through PubMed search of original studies on PBDE concentrations in human individual breast milk specimens collected in the general population over the recent 15-year period (2000-2015) worldwide...
October 2017: Epidemiology
https://www.readbyqxmd.com/read/29027680/determination-of-thiocyanate-as-a-biomarker-of-tobacco-smoke-constituents-in-selected-biological-materials-of-human-origin
#3
Sylwia Narkowicz, Ewa Jaszczak, Żaneta Polkowska, Bogumiła Kiełbratowska, Alicja Kotłowska, Jacek Namieśnik
In order to protect human health, it is necessary to biomonitor toxic substances originating from tobacco smoke in biological materials sampled from the persons with different exposures to tobacco smoke constituents. Thiocyanate anion is a biomarker of exposure to tobacco smoke components which is characterized by a relatively long half-life in the human body, i.e. 6 days. In this work, we present the results of thiocyanate determinations performed on the samples of placenta, meconium, saliva, breast milk, sweat and blood...
October 13, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29026730/important-role-of-medical-training-curriculum-to-promote-the-rate-of-human-milk-feeding
#4
REVIEW
Yong Joo Kim
The rate of human milk feeding has been decreasing despite the diverse efforts of many physicians and nurses, as well as numerous professional organizations and various international health institutions. The number of physicians and nurses who can provide proper guidance for human milk feeding and offer appropriate knowledge and techniques to allow the most beneficial and convenient manner of breastfeeding is quite deficient. It is suggested that physicians and nurses be trained to teach and educate about the medical importance of human milk feeding to lactating mothers...
September 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/29026408/camel-milk-has-beneficial-effects-on-diabetes-mellitus-a-systematic-review
#5
REVIEW
Parvin Mirmiran, Hanieh-Sadat Ejtahed, Pooneh Angoorani, Fariba Eslami, Fereidoun Azizi
CONTEXT: Controlling diabetes, a worldwide metabolic disease, by effective alternative treatments is currently a topic of great interest. Camel milk is believed to be a suitable hypoglycemic agent in experimental animals and patients with diabetes. The current systematic review aimed at evaluating the effect of camel milk on diabetes. EVIDENCE ACQUISITION: A comprehensive search was dine in PubMed and Scopus for all clinical trials and animal studies documented up to 2015, which focused on the effect of camel milk on diabetes markers...
April 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29026146/multiple-approaches-detect-the-presence-of-fungi-in-human-breastmilk-samples-from-healthy-mothers
#6
Alba Boix-Amorós, Cecilia Martinez-Costa, Amparo Querol, Maria Carmen Collado, Alex Mira
Human breastmilk contains a variety of bacteria that are transmitted to the infant and have been suggested to contribute to gut microbiota development and immune maturation. However, the characterization of fungal organisms in milk from healthy mothers is currently unknown although their presence has been reported in the infant gut and also in milk from other mammals. Breastmilk samples from healthy lactating mothers (n = 65) within 1 month after birth were analyzed. Fungal presence was assessed by different techniques, including microscopy, growth and identification of cultured isolates, fungal load estimation by qPCR, and fungal composition using 28S rRNA gene high-throughput sequencing...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29026055/childhood-lead-poisoning-an-overview
#7
REVIEW
K L Hon, C K Fung, A Kc Leung
Childhood lead poisoning is a major public health concern in many countries. In 2015, the Hong Kong SAR Government and its citizens faced a major public health crisis due to the presence of lead in the drinking water of a number of public housing estates. Fortunately, no child was diagnosed with lead poisoning that required treatment with chelation. Lead is a ubiquitous, naturally occurring material that exists in air, dust, soil, and water. It is also widely present in industrial products including petrol, paints, ceramics, food cans, candies, cosmetics, traditional remedies, batteries, solder, stained glass, crystal vessels, ammunition, ceramic glazes, jewelry, and toys...
October 13, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/29026007/milk-fat-components-with-potential-anticancer-activity-a-review
#8
Luis M Rodríguez-Alcalá, M Pilar Castro-Gómez, Lígia L Pimentel, Javier Fontecha
During many years, the milk fat has been unfairly undervalued due to its association with higher levels of cardiovascular diseases, dyslipidaemia or obesity, among others. However, currently, this relationship is being re-evaluated because some of the dairy lipid components have been attributed potential health benefits. Due to this, and based on the increasing incidence of cancer in our society, this review work aims to discuss the state of the art concerning scientific evidences of milk lipid components and reported anticancer properties...
October 12, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/29023054/genetic-characterization-antimicrobial-resistance-patterns-and-virulence-determinants-of-staphylococcus-aureus-isolated-form-bovine-mastitis
#9
Amal Awad, Hazem Ramadan, Sherif Nasr, Ahmed Ateya, Samar Atwa
BACKGROUND AND OBJECTIVE: Staphylococcus aureus is commonly associated with mastitis in dairy herds with potential public health implications. This study was conducted to investigate the existence of S. aureus in mastitic milk and to determine the antimicrobial resistance profiles of the isolated strains as well as the resistance and virulence associated genes. MATERIALS AND METHODS: Two hundred quarter milk samples were collected from 3 dairy farms at Dakahliya (n = 2) and Damietta (n = 1) Governorates, Egypt from September to December 2016...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/29020460/toxoplasma-gondii-infection-and-food-consumption-a-systematic-review-and-meta-analysis-of-case-controlled-studies
#10
Simone Belluco, Giulia Simonato, Marzia Mancin, Mario Pietrobelli, Antonia Ricci
BACKGROUND: Toxoplasmosis is a zoonotic disease causing severe symptoms in pregnant women and immunocompromised individuals. On average, worldwide, around 30% of people are seropositive. The oral transmission route is of great significance and food, particularly meat, is an important transmission vehicle for T. gondii. However, the role of different food matrices is debated. OBJECTIVES: The aim of this review was to assess the risk of humans developing acute T. gondii infection via the foodborne route...
October 11, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29019855/bovine-colostrum-for-preterm-infants-in-the-first-days-of-life-a-randomized-controlled-pilot-trial
#11
Sandra Meinich Juhl, Xuqiang Ye, Ping Zhou, Yanqi Li, Elisabeth Omolabake Iyore, Lixia Zhang, Pingping Jiang, Johannes B van Goudoever, Gorm Greisen, Per Torp Sangild
OBJECTIVES: Mother's own milk (MM) is the best nutrition for newborn preterm infants, but is often limited in supply just after birth. Pasteurized human donor milk (DM), and especially preterm infant formula (IF) are less optimal diets than MM. We hypothesized that it is feasible to use bovine colostrum (BC), the first milk from cows, as a supplement to MM, during the first weeks after preterm birth. METHODS: In an open-label, randomized, controlled pilot safety trial, supplementation of MM with BC was compared with DM supplementation (Danish unit) or IF supplementation (Chinese unit)...
October 10, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29019853/holder-pasteurized-human-donor-milk-how-long-can-it-be-preserved
#12
Marita de Waard, Elise Mank, Karin van Dijk, Anne Schoonderwoerd, Johannes B van Goudoever
OBJECTIVE: When own mother's milk falls short, pasteurized human donor milk is recommended as alternative feeding for preterm infants. Donor milk has to meet the highest safety standards, but its processing and storage is expensive. The recommended storage time of pasteurized donor milk is three months. The objective of this study was to determine if the frozen storage time of pasteurized donor milk can be extended beyond 3 months without compromising its safety and quality. METHODS: For this prospective observational study breast-milk samples of 34 unique women, collected between November 2014 and June 2015, were provided by the Dutch Human Milk Bank...
October 10, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29016385/a-history-into-genetic-and-epigenetic-evolution-of-food-tolerance-how-humanity-rapidly-evolved-by-drinking-milk-and-eating-wheat
#13
Carine Blanchard
PURPOSE OF REVIEW: Human exposure to wheat and milk is almost global worldwide. Yet the introduction of milk and wheat is very recent (5000-10 000 years) when compared to the human evolution. The last 4 decades have seen a rise in food allergy and food intolerance to milk and wheat. Often described as plurifactorial, the cause of allergic diseases is the result from an interplay between genetic predisposition and epigenetic in the context of environmental changes. RECENT FINDINGS: Genetic and epigenetic understanding and their contribution to allergy or other antigen-driven diseases have considerably advanced in the last few years...
October 7, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28993001/absence-of-adventitial-vasa-vasorum-formation-at-the-coronary-segment-with-myocardial-bridge-an-optical-coherence-tomography-study
#14
Kensuke Nishimiya, Yasuharu Matsumoto, Hongxin Wang, Zhonglie Piao, Kazuma Ohyama, Hironori Uzuka, Kiyotaka Hao, Ryuji Tsuburaya, Jun Takahashi, Kenta Ito, Hiroaki Shimokawa
BACKGROUND: Myocardial bridge (MB) is a myocardial bundle through which coronary segment tunnels and could compress coronary arteries causing myocardial ischemia. However, the characteristic structural findings of MB remain to be fully elucidated. Recently, we demonstrated that optical coherence tomography (OCT) enables us to visualize adventitial vasa vasorum (VV) formation in humans. In this study, we examined adventitial VV formation at the coronary segment with MB in humans using OCT...
October 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28990245/effects-of-exposure-to-six-chemical-ultraviolet-filters-commonly-used-in-personal-care-products-on-motility-of-mcf-7-and-mda-mb-231-human-breast-cancer-cells-in-vitro
#15
Maha Alamer, Philippa D Darbre
Benzophenone (BP)-1, BP-2, BP-3, octylmethoxycinnamate (OMC), 4-methylbenzilidenecamphor and homosalate are added to personal care products to absorb ultraviolet light. Their presence in human milk and their oestrogenic activity suggests a potential to influence breast cancer development. As metastatic tumour spread is the main cause of breast cancer mortality, we have investigated the effects of these compounds on migration and invasion of human breast cancer cell lines. Increased motility of oestrogen-responsive MCF-7 human breast cancer cells was observed after long-term exposure (>20 weeks) to each of the six compounds at ≥10(-7)  m concentrations using three independent assay systems (scratch assay, live cell imaging, xCELLigence technology) and increased invasive activity was observed through matrigel using the xCELLigence system...
October 9, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28990226/milk-fatty-acid-profile-from-cows-fed-with-mixed-rations-and-different-access-time-to-pastureland-during-early-lactation
#16
J Barca, M Carriquiry, L Olazabal, M Fajardo, P Chilibroste, A Meikle
Milk fatty acid (FA) profiles were determined in Holstein cows (n = 27) fed total mixed rations (TMR) ad libitum (G0) or diet composed by TMR (50% dry matter [DM] offered) plus grazing of pasture with 6 hr of access time to paddock in one session (G1) or 9 hr in two sessions (G2) at 45 days in milk (DIM). Moreover, milk FA was determined at 65 DIM when G0 cows turned out to G1 diet without adaptation period (Post-G0), G1 remained as controls. Milk FA was quantified using gas chromatography and mass spectrometry...
October 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28988880/gender-proteomics-ii-which-proteins-in-sexual-organs
#17
Elisabetta Gianazza, Ingrid Miller, Uliano Guerrini, Luca Palazzolo, Chiara Parravicini, Ivano Eberini
In continuity with the review dealing with differences by gender in non-sexual organs [1], this review collects data on the proteomes of the sexual organs as involved in human reproduction, under both physiological and pathological conditions. It also collects data on the tissue structures and biological fluids typical of pregnancy, such as placenta and amniotic fluid, as well as what may be tested on preimplantation embryos during medically assisted reproduction. The review includes as well mention to all fluids and secretions connected with sex organs and/or reproduction, including sperm and milk, to exemplify two distinctive items in male and female physiology...
October 5, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28988527/how-fucose-of-blood-group-glycotopes-programs-human-gut-microbiota
#18
REVIEW
S V Kononova
Formation of appropriate gut microbiota is essential for human health. The first two years of life is the critical period for this process. Selection of mutualistic microorganisms of the intestinal microbiota is controlled by the FUT2 and FUT3 genes that encode fucosyltransferases, enzymes responsible for the synthesis of fucosylated glycan structures of mucins and milk oligosaccharides. In this review, the mechanisms of the selection and maintenance of intestinal microorganisms that involve fucosylated oligosaccharides of breast milk and mucins of the newborn's intestine are described...
September 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/28987867/neuroprotective-effect-of-a-new-variant-of-epo-nonhematopoietic-against-oxidative-stress
#19
C Castillo, S Zaror, M Gonzalez, A Hidalgo, C F Burgos, O I Cabezas, F Hugues, S P Jiménez, E González-Horta, I González-Chavarría, J Gavilán, R Montesino, O Sánchez, Manuela G Lopez, J Fuentealba, J R Toledo
Human erythropoietin is mainly recognized for its hematopoietic function; however, by binding to its receptor (EpoR), it can activate different signaling pathways as STAT, PI3K, MAPK and RAS to increase cellular differentiation or provide neuroprotective effects, among others. A recombinant human erythropoietin variant with low glycosylation and without hematopoietic effect (EpoL) was purified from skimmed goat milk. Recombinant human erythropoietin (Epo) was obtained from CHO cell line and used as control to compare EpoL effects...
September 21, 2017: Redox Biology
https://www.readbyqxmd.com/read/28985745/mucus-and-mucins-do-they-have-a-role-in-the-inhibition-of-the-human-immunodeficiency-virus
#20
REVIEW
Anwar Suleman Mall, Habtom Habte, Yolanda Mthembu, Julia Peacocke, Corena de Beer
BACKGROUND: Mucins are large O-linked glycosylated proteins which give mucus their gel-forming properties. There are indications that mucus and mucins in saliva, breast milk and in the cervical plug inhibit the human immunodeficiency virus (HIV-1) in an in vitro assay. Crude mucus gels form continuous layers on the epithelial surfaces of the major internal tracts of the body and protect these epithelial surfaces against aggressive luminal factors such as hydrochloric acid and pepsin proteolysis in the stomach lumen, the movement of hard faecal pellets in the colon at high pressure, the effects of shear against the vaginal epithelium during intercourse and the presence of foreign substances in the respiratory airways...
October 6, 2017: Virology Journal
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